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The map label for this gene is rho [H]

Identifier: 119946796

GI number: 119946796

Start: 3938155

End: 3939423

Strand: Reverse

Name: rho [H]

Synonym: Ping_3189

Alternate gene names: 119946796

Gene position: 3939423-3938155 (Counterclockwise)

Preceding gene: 119946797

Following gene: 119946795

Centisome position: 86.4

GC content: 40.58

Gene sequence:

>1269_bases
ATGAATTTAACTGAATTAAAAGATACACCGGTTTCTAACCTTGTTACGCTTGGGGAATCGATGGGGCTAGAAAATCTAGC
TCGTTTAAGAAAACAAGACATTATATTCGCAATTCTTAAGGCTCACGCCAAAAGTGGGGAAGACATTTTTGGCGCAGGTG
TGCTTGAAATATTGCAAGATGGCTTTGGTTTTTTACGAAGCTCCGAAAGTTCATATCTCGCTGGCCCTGATGATATTTAT
ATCTCGCCAAGCCAAATTCGTCGTTTTAATCTTCGAACAGGTGATAGTGTTGATGGTAAGATCCGTCCGCCTAAAGATGG
TGAGCGTTATTTTGCATTACTGAAAATTATTGAAGTTAACTTCAATAAACCAGAAAACTCTCGTAATAAAATTCTTTTTG
AAAACTTAACCCCCATTCACCCCGATGAGCGTTTTCGTTTAGAAAATGGTAATGGTAGTACAGAAGATATTACGGCACGT
ATTTTGGATTTAGTCTCGCCAATTGGTAAAGGGCAGCGTGGTTTGATCGTTGCACCGCCGAAAGCGGGTAAAACAATGTT
GCTGCAAAATATTGCTCAAAGTCTCAGTATTAATTACCCGGAAGCCGTCTTAATTGTATTATTAATTGATGAGCGTCCGG
AAGAAGTAACTGAAATGAGCCGTTTGGTGAGAGGCGAAGTGGTTGCATCAACTTTTGATGAGCCGGCAAGTCGTCACGTG
CAAGTGGCAGAAATGGTCATTGAAAAAGCGAAACGTCTGGTTGAGCATAAAAAAGATGTTGTTATTCTGCTTGATTCGAT
TACACGTTTGGCACGTGCTTATAATACGGTTGTGCCAAGTTCAGGTAAAGTACTAACAGGTGGTGTTGATGCAAACGCTT
TACAACGCCCTAAGCGCTTCTTTGGTGCAGCTCGTAATGTTGAAGAGGGTGGCAGCTTAACTATCCTAGCAACGGCTCTT
ATCGATACGGGCTCTAAAATGGATGAAGTTATTTATGAAGAGTTTAAAGGTACTGGTAACTCTGAAATTCATCTAAACCG
TAAACTGGCTGAAAAACGGGTTTATCCTGCTATTGATATCACGCGCTCAGGTACAAGGCGTGAAGAACTGCTTACCAAAT
CAGATGAACTACAAAGAATGTGGATTTTGCGTAAAATTGTTCATCCAATGGGCGAAACGGGCGCAACCGAGTTCTTGATT
GATAAGCTTGGTCTAAGCAAAAATAATGATGACTTCTTTGACGCAATGAAAAACCAAAAAGCAAAATAA

Upstream 100 bases:

>100_bases
TTGTGCTCAAAATACAAACAAACAAACAAACAAAAATAAAAATCAATTCCTGACATCACTCATTTATCACTCACTTCAAA
GCTGCATACCTAAAAAACTT

Downstream 100 bases:

>100_bases
TTAGCTTTATTGTGGAAAAAACGCTACTGAAAAGTAGCGTTTTTTTTTGTTTTTTTTCCATTATAAATTGGATCCCTTAT
GAAATTTGATGATTTACGTG

Product: transcription termination factor Rho

Products: NA

Alternate protein names: ATP-dependent helicase Rho [H]

Number of amino acids: Translated: 422; Mature: 422

Protein sequence:

>422_residues
MNLTELKDTPVSNLVTLGESMGLENLARLRKQDIIFAILKAHAKSGEDIFGAGVLEILQDGFGFLRSSESSYLAGPDDIY
ISPSQIRRFNLRTGDSVDGKIRPPKDGERYFALLKIIEVNFNKPENSRNKILFENLTPIHPDERFRLENGNGSTEDITAR
ILDLVSPIGKGQRGLIVAPPKAGKTMLLQNIAQSLSINYPEAVLIVLLIDERPEEVTEMSRLVRGEVVASTFDEPASRHV
QVAEMVIEKAKRLVEHKKDVVILLDSITRLARAYNTVVPSSGKVLTGGVDANALQRPKRFFGAARNVEEGGSLTILATAL
IDTGSKMDEVIYEEFKGTGNSEIHLNRKLAEKRVYPAIDITRSGTRREELLTKSDELQRMWILRKIVHPMGETGATEFLI
DKLGLSKNNDDFFDAMKNQKAK

Sequences:

>Translated_422_residues
MNLTELKDTPVSNLVTLGESMGLENLARLRKQDIIFAILKAHAKSGEDIFGAGVLEILQDGFGFLRSSESSYLAGPDDIY
ISPSQIRRFNLRTGDSVDGKIRPPKDGERYFALLKIIEVNFNKPENSRNKILFENLTPIHPDERFRLENGNGSTEDITAR
ILDLVSPIGKGQRGLIVAPPKAGKTMLLQNIAQSLSINYPEAVLIVLLIDERPEEVTEMSRLVRGEVVASTFDEPASRHV
QVAEMVIEKAKRLVEHKKDVVILLDSITRLARAYNTVVPSSGKVLTGGVDANALQRPKRFFGAARNVEEGGSLTILATAL
IDTGSKMDEVIYEEFKGTGNSEIHLNRKLAEKRVYPAIDITRSGTRREELLTKSDELQRMWILRKIVHPMGETGATEFLI
DKLGLSKNNDDFFDAMKNQKAK
>Mature_422_residues
MNLTELKDTPVSNLVTLGESMGLENLARLRKQDIIFAILKAHAKSGEDIFGAGVLEILQDGFGFLRSSESSYLAGPDDIY
ISPSQIRRFNLRTGDSVDGKIRPPKDGERYFALLKIIEVNFNKPENSRNKILFENLTPIHPDERFRLENGNGSTEDITAR
ILDLVSPIGKGQRGLIVAPPKAGKTMLLQNIAQSLSINYPEAVLIVLLIDERPEEVTEMSRLVRGEVVASTFDEPASRHV
QVAEMVIEKAKRLVEHKKDVVILLDSITRLARAYNTVVPSSGKVLTGGVDANALQRPKRFFGAARNVEEGGSLTILATAL
IDTGSKMDEVIYEEFKGTGNSEIHLNRKLAEKRVYPAIDITRSGTRREELLTKSDELQRMWILRKIVHPMGETGATEFLI
DKLGLSKNNDDFFDAMKNQKAK

Specific function: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template [H]

COG id: COG1158

COG function: function code K; Transcription termination factor

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Rho family [H]

Homologues:

Organism=Escherichia coli, GI1790217, Length=417, Percent_Identity=84.4124700239808, Blast_Score=742, Evalue=0.0,

Paralogues:

None

Copy number: 300 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000194
- InterPro:   IPR003593
- InterPro:   IPR011129
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR011112
- InterPro:   IPR011113
- InterPro:   IPR004665 [H]

Pfam domain/function: PF00006 ATP-synt_ab; PF07498 Rho_N; PF07497 Rho_RNA_bind [H]

EC number: NA

Molecular weight: Translated: 46952; Mature: 46952

Theoretical pI: Translated: 7.19; Mature: 7.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLTELKDTPVSNLVTLGESMGLENLARLRKQDIIFAILKAHAKSGEDIFGAGVLEILQD
CCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
GFGFLRSSESSYLAGPDDIYISPSQIRRFNLRTGDSVDGKIRPPKDGERYFALLKIIEVN
HHHHHHCCCCCCCCCCCCEEECHHHHHEEECCCCCCCCCCCCCCCCHHHHHHHHHHHEEC
FNKPENSRNKILFENLTPIHPDERFRLENGNGSTEDITARILDLVSPIGKGQRGLIVAPP
CCCCCCCCCCEEECCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHCCCCCCCEEEECC
KAGKTMLLQNIAQSLSINYPEAVLIVLLIDERPEEVTEMSRLVRGEVVASTFDEPASRHV
CCCHHHHHHHHHHHHCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCHHHHHH
QVAEMVIEKAKRLVEHKKDVVILLDSITRLARAYNTVVPSSGKVLTGGVDANALQRPKRF
HHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHCCCCCCCEEECCCCCHHHHHHHHH
FGAARNVEEGGSLTILATALIDTGSKMDEVIYEEFKGTGNSEIHLNRKLAEKRVYPAIDI
HHHHCCCCCCCCEEEEEEEHHHCCCHHHHHHHHHHCCCCCCEEEEHHHHHHHHCCCCEEE
TRSGTRREELLTKSDELQRMWILRKIVHPMGETGATEFLIDKLGLSKNNDDFFDAMKNQK
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCHHHHHHHHCCC
AK
CC
>Mature Secondary Structure
MNLTELKDTPVSNLVTLGESMGLENLARLRKQDIIFAILKAHAKSGEDIFGAGVLEILQD
CCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
GFGFLRSSESSYLAGPDDIYISPSQIRRFNLRTGDSVDGKIRPPKDGERYFALLKIIEVN
HHHHHHCCCCCCCCCCCCEEECHHHHHEEECCCCCCCCCCCCCCCCHHHHHHHHHHHEEC
FNKPENSRNKILFENLTPIHPDERFRLENGNGSTEDITARILDLVSPIGKGQRGLIVAPP
CCCCCCCCCCEEECCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHCCCCCCCEEEECC
KAGKTMLLQNIAQSLSINYPEAVLIVLLIDERPEEVTEMSRLVRGEVVASTFDEPASRHV
CCCHHHHHHHHHHHHCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCHHHHHH
QVAEMVIEKAKRLVEHKKDVVILLDSITRLARAYNTVVPSSGKVLTGGVDANALQRPKRF
HHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHCCCCCCCEEECCCCCHHHHHHHHH
FGAARNVEEGGSLTILATALIDTGSKMDEVIYEEFKGTGNSEIHLNRKLAEKRVYPAIDI
HHHHCCCCCCCCEEEEEEEHHHCCCHHHHHHHHHHCCCCCCEEEEHHHHHHHHCCCCEEE
TRSGTRREELLTKSDELQRMWILRKIVHPMGETGATEFLIDKLGLSKNNDDFFDAMKNQK
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCHHHHHHHHCCC
AK
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10993077 [H]