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The map label for this gene is dhaR [H]

Identifier: 119946706

GI number: 119946706

Start: 3793223

End: 3793819

Strand: Reverse

Name: dhaR [H]

Synonym: Ping_3088

Alternate gene names: 119946706

Gene position: 3793819-3793223 (Counterclockwise)

Preceding gene: 119946708

Following gene: 119946705

Centisome position: 83.21

GC content: 48.58

Gene sequence:

>597_bases
ATGGGTATCATGAAATCAAACGATACTCGCAAAAACATTATTCAGGTTGGTGCCAGCCTGATTGCTCAAAAGGGCTTTGG
TGCAACTGGGCTGAACGCGGTGCTTACTAAGTGTGGTGTACCAAAGGGATCCTTCTACTATTATTTTAGCAGTAAGAATG
ATTTCGGCCTGGCGGTGATTGATACCTTCGCTGAAGAATACGATGCCAAGCTGGATCGGATCCTTACGGACAAAACGCGC
TCCTGTATCGAACGGTTGCAGGTCTATTTTTCTACCAGTCTGGAAACCATGACCAACTGTGAATACAAAGAGGGCTGCCT
GATTGGTAATCTAGGTCAGGAACTGGCGGGGCAGAATGAAATGTTCCGAACCCGCCTGAACACGGTATTTACAGCTTGGG
AGATGAAGTTTGCCCTATGCCTGGCTGAAGGCCAGACCGATGGGGATATCAACCCAGACCTTGACCCCCACGATGCAGCC
AGCTTTTTGTTGTCGGGTTGGGAAGGCGCTATTTTGAGGTCTAAAGTACTCAAGTCCTTCGAACCAATGGAGCGATTTAT
TCGGGTGTTTTTTGAACACTGCCTGCGGCCCAGCTAA

Upstream 100 bases:

>100_bases
TAAATTGCCTTAGTTTGAGGGAAGATTAAATACGGCTTTATATTACGTTTAGATATTCATTTCGCCATCAGTTTGACATG
GGATAGACGACCGGTCTAAT

Downstream 100 bases:

>100_bases
TTTTTTGAAAACCATTGTTAGTAAACTGGCCTAATTAATTCCAATTCATTTAAAAGGAAATAACACTATGAGTAACGAAA
ATCAGAAAGACGTATTGTTC

Product: transcriptional regulator of TetR family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 198; Mature: 197

Protein sequence:

>198_residues
MGIMKSNDTRKNIIQVGASLIAQKGFGATGLNAVLTKCGVPKGSFYYYFSSKNDFGLAVIDTFAEEYDAKLDRILTDKTR
SCIERLQVYFSTSLETMTNCEYKEGCLIGNLGQELAGQNEMFRTRLNTVFTAWEMKFALCLAEGQTDGDINPDLDPHDAA
SFLLSGWEGAILRSKVLKSFEPMERFIRVFFEHCLRPS

Sequences:

>Translated_198_residues
MGIMKSNDTRKNIIQVGASLIAQKGFGATGLNAVLTKCGVPKGSFYYYFSSKNDFGLAVIDTFAEEYDAKLDRILTDKTR
SCIERLQVYFSTSLETMTNCEYKEGCLIGNLGQELAGQNEMFRTRLNTVFTAWEMKFALCLAEGQTDGDINPDLDPHDAA
SFLLSGWEGAILRSKVLKSFEPMERFIRVFFEHCLRPS
>Mature_197_residues
GIMKSNDTRKNIIQVGASLIAQKGFGATGLNAVLTKCGVPKGSFYYYFSSKNDFGLAVIDTFAEEYDAKLDRILTDKTRS
CIERLQVYFSTSLETMTNCEYKEGCLIGNLGQELAGQNEMFRTRLNTVFTAWEMKFALCLAEGQTDGDINPDLDPHDAAS
FLLSGWEGAILRSKVLKSFEPMERFIRVFFEHCLRPS

Specific function: Transcriptional repressor for the dhaA haloalkane dehalogenase gene [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH tetR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI145693141, Length=184, Percent_Identity=29.3478260869565, Blast_Score=92, Evalue=2e-20,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR015893
- InterPro:   IPR011075
- InterPro:   IPR001647 [H]

Pfam domain/function: PF00440 TetR_N [H]

EC number: NA

Molecular weight: Translated: 22221; Mature: 22089

Theoretical pI: Translated: 5.35; Mature: 5.35

Prosite motif: PS50977 HTH_TETR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
3.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGIMKSNDTRKNIIQVGASLIAQKGFGATGLNAVLTKCGVPKGSFYYYFSSKNDFGLAVI
CCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCEEEEECCCCCCCHHHH
DTFAEEYDAKLDRILTDKTRSCIERLQVYFSTSLETMTNCEYKEGCLIGNLGQELAGQNE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEECCHHHHHCCCHH
MFRTRLNTVFTAWEMKFALCLAEGQTDGDINPDLDPHDAASFLLSGWEGAILRSKVLKSF
HHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHH
EPMERFIRVFFEHCLRPS
HHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
GIMKSNDTRKNIIQVGASLIAQKGFGATGLNAVLTKCGVPKGSFYYYFSSKNDFGLAVI
CCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCEEEEECCCCCCCHHHH
DTFAEEYDAKLDRILTDKTRSCIERLQVYFSTSLETMTNCEYKEGCLIGNLGQELAGQNE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEECCHHHHHCCCHH
MFRTRLNTVFTAWEMKFALCLAEGQTDGDINPDLDPHDAASFLLSGWEGAILRSKVLKSF
HHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHH
EPMERFIRVFFEHCLRPS
HHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10735862 [H]