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The map label for this gene is yegE [C]

Identifier: 119946695

GI number: 119946695

Start: 3776573

End: 3777886

Strand: Reverse

Name: yegE [C]

Synonym: Ping_3077

Alternate gene names: 119946695

Gene position: 3777886-3776573 (Counterclockwise)

Preceding gene: 119946697

Following gene: 119946694

Centisome position: 82.86

GC content: 33.56

Gene sequence:

>1314_bases
ATGAGCCTGCGTACTAAATTATCACTGTTACTTGTTTTTCTCTTTGTCTTCTCTATTGGTAATACTTTATTTACTTTCGT
CTTGGATAAGTTTGGAGAAGAAAAGCTTGGATGGGTAATACATACGCATGAGGTTTTAAATAGCGCACAAAAATTATTAA
GTTCGATGACCGATGCAGAAACAGGGCAAAGGGGTTTTTTACTGACGGGGAATCCTGATTACTTAGCGCCATATCTTAAG
GGCATACTTTCATCGGAACAAAGTTTCAATAATTTATCTGGTTTGACATCAGACAATCCTAAACAGACAAAACGCTTGAA
TGATATTAAAGCATTTATGGAAAAGAAGTTTATAGAATTAAAACTAACAATTGAACTTTATCAAAGTGGCAATACGGAAG
ATAAAAGAAAGGCGATTGAGATAGTAGAGCAGAATACCGGTAAAAAAATGATGGATGAGATAAGGCTTCAAATTACTTTA
TTCACGAATCATGAGCATTTATTATTAGAAAGAAGAAAGGCTGATTTCAGAGAAAGCAGAGCACAGTTGACTACTATAGT
GATTATTGAGCTTATATTATTTGTATTTTTAGGAATAATAACAATGTTTTTCATAAGGGAAAGGTTATTTTCTCCACTCA
AATTGTTGCTTTTAAATGCCGAGAAAATGGAAAGGGGAGAAAGACAAAATATTGAAGATATTTTGCCTAAAGATGAAATG
GGCTACTTACTCTCTCGTTTTTATCAAGTAAGTGAAAAAATTTATACCGATACTGAAATATTAACCTATGAAGCAACTCA
TGATGCTTTGACCGGTTTAGCCAATAGAGTAGGGATTGATATAGCAATTAGGCACTCTATTGCAGCTATAGCAGGCAGTG
ATAGAAAAATGGCTGTTCTTTTTATCGATCTCAATAAATTTAAAAAACTTAATGATACTCTGGGGCATGATGCGGGAGAT
GCCGTTCTAAAAGAGACTGCTAATCGCCTTAAAGAGGCTTTACGTTCTGATGATAAGGCGTTTCGCTTAGGAGGGGACGA
GTTTGTTATCGCTTTAAATGATCTTTCTGAGATATCACATATTAAAATTGTAGTGGATAATATATTAGATAAATTTAAAT
CACCGTTTATATTCAACAATGATCCTATTGAAATTTCTCTGAGTATAGGCATCGCGATTGCACCTGACAATTCAACAGAT
AGTGAAGCAATATTAAAATTCTCAGATATCGCAATGTACATGGCTAAACATAATAAAAATCATAATTACAGTTTCTCTGA
CAAAACCATGCTGAAACGTGAAAATGATAAATAG

Upstream 100 bases:

>100_bases
AAGCAAATATTAGTCCTATCTAGTTGGAAAGGTTAGGCAATCTGGCCTATATAATGAGAATTATTGATCTGTTGAAGTAT
CAACTTAAAGGATTGGTTTA

Downstream 100 bases:

>100_bases
TATAGCTGGAAGTATTCAGCCTGCAAGTCCCACAGCACAACGCTCCGCACAGGGTGGTTCATTTTTCTTTATTAATATTA
AATACTTACTCACACTTGCT

Product: diguanylate cyclase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 437; Mature: 436

Protein sequence:

>437_residues
MSLRTKLSLLLVFLFVFSIGNTLFTFVLDKFGEEKLGWVIHTHEVLNSAQKLLSSMTDAETGQRGFLLTGNPDYLAPYLK
GILSSEQSFNNLSGLTSDNPKQTKRLNDIKAFMEKKFIELKLTIELYQSGNTEDKRKAIEIVEQNTGKKMMDEIRLQITL
FTNHEHLLLERRKADFRESRAQLTTIVIIELILFVFLGIITMFFIRERLFSPLKLLLLNAEKMERGERQNIEDILPKDEM
GYLLSRFYQVSEKIYTDTEILTYEATHDALTGLANRVGIDIAIRHSIAAIAGSDRKMAVLFIDLNKFKKLNDTLGHDAGD
AVLKETANRLKEALRSDDKAFRLGGDEFVIALNDLSEISHIKIVVDNILDKFKSPFIFNNDPIEISLSIGIAIAPDNSTD
SEAILKFSDIAMYMAKHNKNHNYSFSDKTMLKRENDK

Sequences:

>Translated_437_residues
MSLRTKLSLLLVFLFVFSIGNTLFTFVLDKFGEEKLGWVIHTHEVLNSAQKLLSSMTDAETGQRGFLLTGNPDYLAPYLK
GILSSEQSFNNLSGLTSDNPKQTKRLNDIKAFMEKKFIELKLTIELYQSGNTEDKRKAIEIVEQNTGKKMMDEIRLQITL
FTNHEHLLLERRKADFRESRAQLTTIVIIELILFVFLGIITMFFIRERLFSPLKLLLLNAEKMERGERQNIEDILPKDEM
GYLLSRFYQVSEKIYTDTEILTYEATHDALTGLANRVGIDIAIRHSIAAIAGSDRKMAVLFIDLNKFKKLNDTLGHDAGD
AVLKETANRLKEALRSDDKAFRLGGDEFVIALNDLSEISHIKIVVDNILDKFKSPFIFNNDPIEISLSIGIAIAPDNSTD
SEAILKFSDIAMYMAKHNKNHNYSFSDKTMLKRENDK
>Mature_436_residues
SLRTKLSLLLVFLFVFSIGNTLFTFVLDKFGEEKLGWVIHTHEVLNSAQKLLSSMTDAETGQRGFLLTGNPDYLAPYLKG
ILSSEQSFNNLSGLTSDNPKQTKRLNDIKAFMEKKFIELKLTIELYQSGNTEDKRKAIEIVEQNTGKKMMDEIRLQITLF
TNHEHLLLERRKADFRESRAQLTTIVIIELILFVFLGIITMFFIRERLFSPLKLLLLNAEKMERGERQNIEDILPKDEMG
YLLSRFYQVSEKIYTDTEILTYEATHDALTGLANRVGIDIAIRHSIAAIAGSDRKMAVLFIDLNKFKKLNDTLGHDAGDA
VLKETANRLKEALRSDDKAFRLGGDEFVIALNDLSEISHIKIVVDNILDKFKSPFIFNNDPIEISLSIGIAIAPDNSTDS
EAILKFSDIAMYMAKHNKNHNYSFSDKTMLKRENDK

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788381, Length=159, Percent_Identity=35.8490566037736, Blast_Score=104, Evalue=1e-23,
Organism=Escherichia coli, GI1787541, Length=169, Percent_Identity=33.1360946745562, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1788956, Length=156, Percent_Identity=37.8205128205128, Blast_Score=99, Evalue=4e-22,
Organism=Escherichia coli, GI145693134, Length=160, Percent_Identity=35, Blast_Score=92, Evalue=7e-20,
Organism=Escherichia coli, GI1786584, Length=173, Percent_Identity=31.7919075144509, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI87082007, Length=166, Percent_Identity=31.9277108433735, Blast_Score=78, Evalue=9e-16,
Organism=Escherichia coli, GI87081974, Length=157, Percent_Identity=33.1210191082803, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI87081977, Length=211, Percent_Identity=29.3838862559242, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1787262, Length=134, Percent_Identity=29.1044776119403, Blast_Score=72, Evalue=9e-14,
Organism=Escherichia coli, GI87081881, Length=173, Percent_Identity=33.5260115606936, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1787816, Length=180, Percent_Identity=28.8888888888889, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR005330
- InterPro:   IPR000014
- InterPro:   IPR013767 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF03707 MHYT; PF00989 PAS [H]

EC number: NA

Molecular weight: Translated: 49830; Mature: 49699

Theoretical pI: Translated: 6.53; Mature: 6.53

Prosite motif: PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLRTKLSLLLVFLFVFSIGNTLFTFVLDKFGEEKLGWVIHTHEVLNSAQKLLSSMTDAE
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCEEEHHHHHHHHHHHHHHHHHCC
TGQRGFLLTGNPDYLAPYLKGILSSEQSFNNLSGLTSDNPKQTKRLNDIKAFMEKKFIEL
CCCCCEEEECCCCHHHHHHHHHHHCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHEEE
KLTIELYQSGNTEDKRKAIEIVEQNTGKKMMDEIRLQITLFTNHEHLLLERRKADFRESR
EEEEEEECCCCCHHHHHHHHHHHHCCCHHHHHHHEEEEEEEECCHHHHHHHHHHHHHHHH
AQLTTIVIIELILFVFLGIITMFFIRERLFSPLKLLLLNAEKMERGERQNIEDILPKDEM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHCCCCCCHHHCCCCCHH
GYLLSRFYQVSEKIYTDTEILTYEATHDALTGLANRVGIDIAIRHSIAAIAGSDRKMAVL
HHHHHHHHHHHHHHCCCCEEEEEECHHHHHHHHHHHHCEEEEEHHHHHHHCCCCCEEEEE
FIDLNKFKKLNDTLGHDAGDAVLKETANRLKEALRSDDKAFRLGGDEFVIALNDLSEISH
EEEHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCEEEECCCEEEEEECCCCHHHH
IKIVVDNILDKFKSPFIFNNDPIEISLSIGIAIAPDNSTDSEAILKFSDIAMYMAKHNKN
HHHHHHHHHHHHCCCCEECCCCEEEEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCC
HNYSFSDKTMLKRENDK
CCCCCCCHHHHHCCCCC
>Mature Secondary Structure 
SLRTKLSLLLVFLFVFSIGNTLFTFVLDKFGEEKLGWVIHTHEVLNSAQKLLSSMTDAE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCEEEHHHHHHHHHHHHHHHHHCC
TGQRGFLLTGNPDYLAPYLKGILSSEQSFNNLSGLTSDNPKQTKRLNDIKAFMEKKFIEL
CCCCCEEEECCCCHHHHHHHHHHHCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHEEE
KLTIELYQSGNTEDKRKAIEIVEQNTGKKMMDEIRLQITLFTNHEHLLLERRKADFRESR
EEEEEEECCCCCHHHHHHHHHHHHCCCHHHHHHHEEEEEEEECCHHHHHHHHHHHHHHHH
AQLTTIVIIELILFVFLGIITMFFIRERLFSPLKLLLLNAEKMERGERQNIEDILPKDEM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHCCCCCCHHHCCCCCHH
GYLLSRFYQVSEKIYTDTEILTYEATHDALTGLANRVGIDIAIRHSIAAIAGSDRKMAVL
HHHHHHHHHHHHHHCCCCEEEEEECHHHHHHHHHHHHCEEEEEHHHHHHHCCCCCEEEEE
FIDLNKFKKLNDTLGHDAGDAVLKETANRLKEALRSDDKAFRLGGDEFVIALNDLSEISH
EEEHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCEEEECCCEEEEEECCCCHHHH
IKIVVDNILDKFKSPFIFNNDPIEISLSIGIAIAPDNSTDSEAILKFSDIAMYMAKHNKN
HHHHHHHHHHHHCCCCEECCCCEEEEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCC
HNYSFSDKTMLKRENDK
CCCCCCCHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11259647 [H]