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The map label for this gene is htpX [H]

Identifier: 119945607

GI number: 119945607

Start: 2342689

End: 2343555

Strand: Reverse

Name: htpX [H]

Synonym: Ping_1916

Alternate gene names: 119945607

Gene position: 2343555-2342689 (Counterclockwise)

Preceding gene: 119945609

Following gene: 119945606

Centisome position: 51.4

GC content: 40.83

Gene sequence:

>867_bases
ATGAAACGTATCGCTTTATTTTTACTAACAAACTTAGCTGTTATGCTGGTCTTAGGTATTGTACTGAGTTTGGTTTTTAG
GTTTACGGGATTAGATTCACGCAGTCTCGGAGGTCTACTCCTATTGGCCGCTGTTTTCGGTTTTGGAGGATCATTTATCT
CTTTAGCTATGTCAAAGTGGATAGCAAAACGCAGTACTGGTGCAGTGGTCATTACACAACCCAATAATGAAACTGAAAAC
TGGCTTGTTAATACCGTTGCAGCGCAAGCTAAAAAGGCTGGAATTCGCTGTCCTGAAGTGGCCATTTATGATGCGCCGGA
TATGAATGCTTTTGCCACCGGTATGAATAAAAACAAAGCCTTAGTTGCCGTTAGCTCTGGTTTATTGCAATCTATGACAC
GCGATGAAGCAGAAGCTGTTTTAGCCCATGAAGTGAGTCATATTGCCAGCGGTGATATGGTAACAATGACGCTACTTCAA
GGCGTGGTAAATACCTTTGTTATCTTTATTGCCCGTGTTTTAGGGAATATTATTGACAGTGCGCTAAACAATAATAATTC
TGAATCTGAGGGGCGTGGGTTTTCTTATTATATTATTGTGTTTATTTTAGAAATGATCTTTGGCGTACTGGCAAGTACGA
TCGTAATGTACTACTCCCGCCAACGAGAATTTAGTGCAGATTCTGGTGCCGCTAGATTAGTAGGGAAAAACAAAATGATC
GCTGCATTACAGCGTTTACAAAAAAGTTCTGAGCCTCATTTGGAGGGTAATATGATGGCATTTGGTATTTCAGGAAAATC
CAGCGGCGGATTATTTATGTCTCACCCGCCCTTAGAAAGTCGCATTAAAGCACTACAAGAAGCATAA

Upstream 100 bases:

>100_bases
CGTTATTAGTTTGATTTTAATATTTATTTTTAATCACCTATTGAAAAACCAAATTATAGCCATATTATGTCTTTATTGAT
TTATCCATCTTGAGGTTTTT

Downstream 100 bases:

>100_bases
TGACTTATTAGTGCTATTAAATATAAAAACACCGTTATTTTTTATAACAGCGGTGTTTTTAACTGTCCTTATTGTATTTT
TCTGCCACAATCTTAAATGC

Product: heat shock protein HtpX

Products: NA

Alternate protein names: Heat shock protein HtpX [H]

Number of amino acids: Translated: 288; Mature: 288

Protein sequence:

>288_residues
MKRIALFLLTNLAVMLVLGIVLSLVFRFTGLDSRSLGGLLLLAAVFGFGGSFISLAMSKWIAKRSTGAVVITQPNNETEN
WLVNTVAAQAKKAGIRCPEVAIYDAPDMNAFATGMNKNKALVAVSSGLLQSMTRDEAEAVLAHEVSHIASGDMVTMTLLQ
GVVNTFVIFIARVLGNIIDSALNNNNSESEGRGFSYYIIVFILEMIFGVLASTIVMYYSRQREFSADSGAARLVGKNKMI
AALQRLQKSSEPHLEGNMMAFGISGKSSGGLFMSHPPLESRIKALQEA

Sequences:

>Translated_288_residues
MKRIALFLLTNLAVMLVLGIVLSLVFRFTGLDSRSLGGLLLLAAVFGFGGSFISLAMSKWIAKRSTGAVVITQPNNETEN
WLVNTVAAQAKKAGIRCPEVAIYDAPDMNAFATGMNKNKALVAVSSGLLQSMTRDEAEAVLAHEVSHIASGDMVTMTLLQ
GVVNTFVIFIARVLGNIIDSALNNNNSESEGRGFSYYIIVFILEMIFGVLASTIVMYYSRQREFSADSGAARLVGKNKMI
AALQRLQKSSEPHLEGNMMAFGISGKSSGGLFMSHPPLESRIKALQEA
>Mature_288_residues
MKRIALFLLTNLAVMLVLGIVLSLVFRFTGLDSRSLGGLLLLAAVFGFGGSFISLAMSKWIAKRSTGAVVITQPNNETEN
WLVNTVAAQAKKAGIRCPEVAIYDAPDMNAFATGMNKNKALVAVSSGLLQSMTRDEAEAVLAHEVSHIASGDMVTMTLLQ
GVVNTFVIFIARVLGNIIDSALNNNNSESEGRGFSYYIIVFILEMIFGVLASTIVMYYSRQREFSADSGAARLVGKNKMI
AALQRLQKSSEPHLEGNMMAFGISGKSSGGLFMSHPPLESRIKALQEA

Specific function: Unknown Function. Overexpression Of A Truncated Form Of The Htpx Protein Leads To An Increase In The Degradation Of Abnormal Proteins. [C]

COG id: COG0501

COG function: function code O; Zn-dependent protease with chaperone function

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M48B family [H]

Homologues:

Organism=Escherichia coli, GI1788133, Length=291, Percent_Identity=60.8247422680412, Blast_Score=353, Evalue=6e-99,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022919
- InterPro:   IPR001915 [H]

Pfam domain/function: PF01435 Peptidase_M48 [H]

EC number: 3.4.24.-

Molecular weight: Translated: 31004; Mature: 31004

Theoretical pI: Translated: 9.66; Mature: 9.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
4.9 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRIALFLLTNLAVMLVLGIVLSLVFRFTGLDSRSLGGLLLLAAVFGFGGSFISLAMSKW
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHH
IAKRSTGAVVITQPNNETENWLVNTVAAQAKKAGIRCPEVAIYDAPDMNAFATGMNKNKA
HHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCHHHCCCCCCCE
LVAVSSGLLQSMTRDEAEAVLAHEVSHIASGDMVTMTLLQGVVNTFVIFIARVLGNIIDS
EEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALNNNNSESEGRGFSYYIIVFILEMIFGVLASTIVMYYSRQREFSADSGAARLVGKNKMI
HHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCHHHH
AALQRLQKSSEPHLEGNMMAFGISGKSSGGLFMSHPPLESRIKALQEA
HHHHHHHHCCCCCCCCCEEEEEECCCCCCCEEEECCCHHHHHHHHHCC
>Mature Secondary Structure
MKRIALFLLTNLAVMLVLGIVLSLVFRFTGLDSRSLGGLLLLAAVFGFGGSFISLAMSKW
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHH
IAKRSTGAVVITQPNNETENWLVNTVAAQAKKAGIRCPEVAIYDAPDMNAFATGMNKNKA
HHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCHHHCCCCCCCE
LVAVSSGLLQSMTRDEAEAVLAHEVSHIASGDMVTMTLLQGVVNTFVIFIARVLGNIIDS
EEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALNNNNSESEGRGFSYYIIVFILEMIFGVLASTIVMYYSRQREFSADSGAARLVGKNKMI
HHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCHHHH
AALQRLQKSSEPHLEGNMMAFGISGKSSGGLFMSHPPLESRIKALQEA
HHHHHHHHCCCCCCCCCEEEEEECCCCCCCEEEECCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA