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The map label for this gene is hisC [H]

Identifier: 119945367

GI number: 119945367

Start: 2011902

End: 2012972

Strand: Reverse

Name: hisC [H]

Synonym: Ping_1655

Alternate gene names: 119945367

Gene position: 2012972-2011902 (Counterclockwise)

Preceding gene: 119945368

Following gene: 119945366

Centisome position: 44.15

GC content: 44.26

Gene sequence:

>1071_bases
ATGAGCAGCATCAAACACCTTGCCCGTGAAACGGTGCAAGCATTAACACCTTACCTTTCCGCACGTCGCATTGGTGGCAC
GGGAGACGTTTGGTTAAACGCGAATGAATCTCCAGACTGCAGTGAATATCAACTCGACTCGAGTAAACTCAATCGCTACC
CTGAATTTCAACCACATTCATTAATTACAGCCTATGCCGATTATGCTGCTGTTAAACACAGCCAAGTTTTAAGCACCCGC
GGCGCTGATGAAAGTATTGAAATACTGATCCGCACTTTTTGTGAGCCCAGTGCAGACAGTATTTTAATCTGCCCACCAAC
CTACGGCATGTATGCAATCAGTGCTGAAACCTGCGGTGTTGCAATTGAAGAGGTCGCCTTAGCAGATAACTTTGATGTTG
ATTATCAAGCAGTTGAAAATTCGGTAACAAAAGTCGACAGTCAGGTTAAATTAGTCTTCCTATGTGCGCCTAACAATCCC
ACTGGTAATATACTCGACCGGCAGAAACTGATCGCATTGCTGCAGGCAACAAAAGGCAAAGCGTTAATTGTCGCGGATGA
AGCCTATATTGAATTTTGTCCCAAATTAAGCCAGGCAGATTTGATTGCACAATATGAAAATCTGGTTATCACCCGAACCC
TGTCAAAGGCTTTTGCCCTGGCTGCTATCCGTTGTGGTTTTACTCTGGCACAGGAATCGGTTATTGAGATGTTATCAAAA
GTCATTGCGCCTTATCCGGTTCCAGCCCCCGTTGCACAGATCGCCACGCAGGCACTATCAAAAGACGGCTTGGCGGTTAT
GTTTGAGCGCGTAAAAATACTTAATAACAACCGCCAACTGTTACAAGATGCACTGCAGGACATTGATTGTGTCACAGAGA
TTTTTCAGGCAACCGGTAACTTTTTATTAGTGCGCTTTAAAGACTCAGTAAAAGTATTCGCAGCCTTTGCCAAAAATGGC
ATTATTATGCGCGACTTTGCCAATAAGCCACGTTTAAAAAACTGTATTCGCATTACTATCGGCACAGAAGCTGAAATGCA
GGCAACATTAACCACCTTAAACTCGCTATAG

Upstream 100 bases:

>100_bases
GTTAACTTTTAATAATTTTGGGCAAATGTTGAGTGTTATAAAACAGGCACGCTAACATTTGCCGCGGACATCAGAAATTA
TTTGCTAGGGAATAAAATAC

Downstream 100 bases:

>100_bases
GAAATAAATAATGAGCAAACAAAAATTTCTATTCATCGATCGTGATGGTACTTTAATTGATGAGCCCATCAGCGACAAAC
AGGTTGATAGTTTAGAAAAA

Product: histidinol-phosphate aminotransferase

Products: NA

Alternate protein names: Imidazole acetol-phosphate transaminase [H]

Number of amino acids: Translated: 356; Mature: 355

Protein sequence:

>356_residues
MSSIKHLARETVQALTPYLSARRIGGTGDVWLNANESPDCSEYQLDSSKLNRYPEFQPHSLITAYADYAAVKHSQVLSTR
GADESIEILIRTFCEPSADSILICPPTYGMYAISAETCGVAIEEVALADNFDVDYQAVENSVTKVDSQVKLVFLCAPNNP
TGNILDRQKLIALLQATKGKALIVADEAYIEFCPKLSQADLIAQYENLVITRTLSKAFALAAIRCGFTLAQESVIEMLSK
VIAPYPVPAPVAQIATQALSKDGLAVMFERVKILNNNRQLLQDALQDIDCVTEIFQATGNFLLVRFKDSVKVFAAFAKNG
IIMRDFANKPRLKNCIRITIGTEAEMQATLTTLNSL

Sequences:

>Translated_356_residues
MSSIKHLARETVQALTPYLSARRIGGTGDVWLNANESPDCSEYQLDSSKLNRYPEFQPHSLITAYADYAAVKHSQVLSTR
GADESIEILIRTFCEPSADSILICPPTYGMYAISAETCGVAIEEVALADNFDVDYQAVENSVTKVDSQVKLVFLCAPNNP
TGNILDRQKLIALLQATKGKALIVADEAYIEFCPKLSQADLIAQYENLVITRTLSKAFALAAIRCGFTLAQESVIEMLSK
VIAPYPVPAPVAQIATQALSKDGLAVMFERVKILNNNRQLLQDALQDIDCVTEIFQATGNFLLVRFKDSVKVFAAFAKNG
IIMRDFANKPRLKNCIRITIGTEAEMQATLTTLNSL
>Mature_355_residues
SSIKHLARETVQALTPYLSARRIGGTGDVWLNANESPDCSEYQLDSSKLNRYPEFQPHSLITAYADYAAVKHSQVLSTRG
ADESIEILIRTFCEPSADSILICPPTYGMYAISAETCGVAIEEVALADNFDVDYQAVENSVTKVDSQVKLVFLCAPNNPT
GNILDRQKLIALLQATKGKALIVADEAYIEFCPKLSQADLIAQYENLVITRTLSKAFALAAIRCGFTLAQESVIEMLSKV
IAPYPVPAPVAQIATQALSKDGLAVMFERVKILNNNRQLLQDALQDIDCVTEIFQATGNFLLVRFKDSVKVFAAFAKNGI
IMRDFANKPRLKNCIRITIGTEAEMQATLTTLNSL

Specific function: Histidine biosynthesis; seventh step. [C]

COG id: COG0079

COG function: function code E; Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788332, Length=353, Percent_Identity=54.6742209631728, Blast_Score=395, Evalue=1e-111,
Organism=Saccharomyces cerevisiae, GI6322075, Length=369, Percent_Identity=32.2493224932249, Blast_Score=168, Evalue=1e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001917
- InterPro:   IPR004839
- InterPro:   IPR005861
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.9 [H]

Molecular weight: Translated: 39068; Mature: 38937

Theoretical pI: Translated: 5.08; Mature: 5.08

Prosite motif: PS00599 AA_TRANSFER_CLASS_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSIKHLARETVQALTPYLSARRIGGTGDVWLNANESPDCSEYQLDSSKLNRYPEFQPHS
CCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCEECCHHHHCCCCCCCCCH
LITAYADYAAVKHSQVLSTRGADESIEILIRTFCEPSADSILICPPTYGMYAISAETCGV
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCEEEECCCCCCEEEEECHHHCH
AIEEVALADNFDVDYQAVENSVTKVDSQVKLVFLCAPNNPTGNILDRQKLIALLQATKGK
HHHHHHHCCCCCCHHHHHHHHHHHCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHCCCCC
ALIVADEAYIEFCPKLSQADLIAQYENLVITRTLSKAFALAAIRCGFTLAQESVIEMLSK
EEEEECHHHHHHCCCCCHHHHHHHHHHEEEEHHHHHHHHHHHHHHCHHHHHHHHHHHHHH
VIAPYPVPAPVAQIATQALSKDGLAVMFERVKILNNNRQLLQDALQDIDCVTEIFQATGN
HHCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCC
FLLVRFKDSVKVFAAFAKNGIIMRDFANKPRLKNCIRITIGTEAEMQATLTTLNSL
EEEEEECCHHHHHHHHHHCCEEEECCCCCCCCCCEEEEEECCCCHHHHHHHHHHCC
>Mature Secondary Structure 
SSIKHLARETVQALTPYLSARRIGGTGDVWLNANESPDCSEYQLDSSKLNRYPEFQPHS
CHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCEECCHHHHCCCCCCCCCH
LITAYADYAAVKHSQVLSTRGADESIEILIRTFCEPSADSILICPPTYGMYAISAETCGV
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCEEEECCCCCCEEEEECHHHCH
AIEEVALADNFDVDYQAVENSVTKVDSQVKLVFLCAPNNPTGNILDRQKLIALLQATKGK
HHHHHHHCCCCCCHHHHHHHHHHHCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHCCCCC
ALIVADEAYIEFCPKLSQADLIAQYENLVITRTLSKAFALAAIRCGFTLAQESVIEMLSK
EEEEECHHHHHHCCCCCHHHHHHHHHHEEEEHHHHHHHHHHHHHHCHHHHHHHHHHHHHH
VIAPYPVPAPVAQIATQALSKDGLAVMFERVKILNNNRQLLQDALQDIDCVTEIFQATGN
HHCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCC
FLLVRFKDSVKVFAAFAKNGIIMRDFANKPRLKNCIRITIGTEAEMQATLTTLNSL
EEEEEECCHHHHHHHHHHCCEEEECCCCCCCCCCEEEEEECCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA