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The map label for this gene is insF1 [C]

Identifier: 119945352

GI number: 119945352

Start: 1996643

End: 1997551

Strand: Reverse

Name: insF1 [C]

Synonym: Ping_1638

Alternate gene names: 119945352

Gene position: 1997551-1996643 (Counterclockwise)

Preceding gene: 119945353

Following gene: 119945341

Centisome position: 43.81

GC content: 40.26

Gene sequence:

>909_bases
ATGTGTCGCGTCATGCAGGTAAGTTCAAGTGCGTTTTATGCTTGGGAAAATACGGCGATTAAACCTTTTGACACATTAGG
TTTTAATCTAGACTGCACCGTGAAGAATACCTTTAAAACGCACAGAATGACCTTAGGTAGTAGGCGTATGGTGACTGAAC
TGGCAAAGCAAAACATTGTTATAGGTCGTTATAAAGCACGCTCAACCATGCGTAAATTAGGGCTTGTGGCGCGATACCCC
AAGAAATATCAAACGACCACTGACAGTAACCACAATAATCGAATTGAACCGAATAAATTAAATAGGCAATTCACTGTTGA
AGAAGCTAATCACTATTGGACTACCGATATTACTTATATCGCCACGCATCAAGGGTTTATCTATTTAGCGATCGTCATGG
ACTTATATTCGCGCCGTATAGTTGGTTGGTCTATTGCAGATAATATGCGTACTGAACTATGTAGTAACGCCCTTGATATG
GCCTATTGGCAGAGAAAACCAGCATCGGGATTACTGCATCATTCCGATAGGGGGAGCCAGTATACAAGCGATGATTATAG
GAAATTACTTAGCACCATGGAAATGGATGTTAGCATGAGCGGTAAAGGGGAATGCTGGGACAATGCCCCCACAGAGCGAT
TTTTCCGTAGTTTAAAACATGAGCAATTAAACTATGAAACATTCAAAACGAAGAAAGCAGCAGAACTAAGCATTTTAGAT
TATCTTGCTTATTACAACGGTAAGCGCCCACATTCAGTTAATGGGTACTTATCTCCTATTCAATATGAGAATAAAGTCGC
TAAGAAAGTATCCAGTTTTTATTCACCATTACAGGGAGACCCCAATGATTTTGTGATTTTGGACACAACTCCTAAACAGG
TGTGCCTGCTTCAGCTTGTTTTAAAATAG

Upstream 100 bases:

>100_bases
AGCGTGATATTTTAAAAAAGGCCGCAGTCTTCTTTGCGAACGAAAAATAATAAGATTTCAATTTATTCAACAACACAAAG
AAGACTGGCCAATTAAAGTA

Downstream 100 bases:

>100_bases
CCATAATTTGGCTGTCAGAATAATGTGATTTTTTCATGCAGAATCTCCTGCGATTAGTTTACGAGAAAATTCTACTTGTG
AATTCAATTTTTTTTCGTGG

Product: integrase catalytic subunit

Products: NA

Alternate protein names: ISO-S3 31 kDa protein [H]

Number of amino acids: Translated: 302; Mature: 302

Protein sequence:

>302_residues
MCRVMQVSSSAFYAWENTAIKPFDTLGFNLDCTVKNTFKTHRMTLGSRRMVTELAKQNIVIGRYKARSTMRKLGLVARYP
KKYQTTTDSNHNNRIEPNKLNRQFTVEEANHYWTTDITYIATHQGFIYLAIVMDLYSRRIVGWSIADNMRTELCSNALDM
AYWQRKPASGLLHHSDRGSQYTSDDYRKLLSTMEMDVSMSGKGECWDNAPTERFFRSLKHEQLNYETFKTKKAAELSILD
YLAYYNGKRPHSVNGYLSPIQYENKVAKKVSSFYSPLQGDPNDFVILDTTPKQVCLLQLVLK

Sequences:

>Translated_302_residues
MCRVMQVSSSAFYAWENTAIKPFDTLGFNLDCTVKNTFKTHRMTLGSRRMVTELAKQNIVIGRYKARSTMRKLGLVARYP
KKYQTTTDSNHNNRIEPNKLNRQFTVEEANHYWTTDITYIATHQGFIYLAIVMDLYSRRIVGWSIADNMRTELCSNALDM
AYWQRKPASGLLHHSDRGSQYTSDDYRKLLSTMEMDVSMSGKGECWDNAPTERFFRSLKHEQLNYETFKTKKAAELSILD
YLAYYNGKRPHSVNGYLSPIQYENKVAKKVSSFYSPLQGDPNDFVILDTTPKQVCLLQLVLK
>Mature_302_residues
MCRVMQVSSSAFYAWENTAIKPFDTLGFNLDCTVKNTFKTHRMTLGSRRMVTELAKQNIVIGRYKARSTMRKLGLVARYP
KKYQTTTDSNHNNRIEPNKLNRQFTVEEANHYWTTDITYIATHQGFIYLAIVMDLYSRRIVGWSIADNMRTELCSNALDM
AYWQRKPASGLLHHSDRGSQYTSDDYRKLLSTMEMDVSMSGKGECWDNAPTERFFRSLKHEQLNYETFKTKKAAELSILD
YLAYYNGKRPHSVNGYLSPIQYENKVAKKVSSFYSPLQGDPNDFVILDTTPKQVCLLQLVLK

Specific function: Involved in the transposition of the insertion sequence is3 [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 integrase catalytic domain [H]

Homologues:

Organism=Homo sapiens, GI310129419, Length=230, Percent_Identity=29.5652173913043, Blast_Score=117, Evalue=1e-26,
Organism=Escherichia coli, GI1788405, Length=268, Percent_Identity=36.1940298507463, Blast_Score=179, Evalue=2e-46,
Organism=Escherichia coli, GI1787263, Length=268, Percent_Identity=36.1940298507463, Blast_Score=179, Evalue=2e-46,
Organism=Escherichia coli, GI1786753, Length=268, Percent_Identity=36.1940298507463, Blast_Score=179, Evalue=2e-46,
Organism=Escherichia coli, GI1786570, Length=268, Percent_Identity=36.1940298507463, Blast_Score=179, Evalue=2e-46,
Organism=Escherichia coli, GI1786490, Length=268, Percent_Identity=36.1940298507463, Blast_Score=179, Evalue=2e-46,
Organism=Escherichia coli, GI1789981, Length=266, Percent_Identity=28.1954887218045, Blast_Score=109, Evalue=2e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001584
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00665 rve [H]

EC number: NA

Molecular weight: Translated: 34994; Mature: 34994

Theoretical pI: Translated: 9.67; Mature: 9.67

Prosite motif: PS50994 INTEGRASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCRVMQVSSSAFYAWENTAIKPFDTLGFNLDCTVKNTFKTHRMTLGSRRMVTELAKQNIV
CCEEEEECCCEEEEECCCCCCCHHHCCCCEEEEECCCHHHHHHHCCCHHHHHHHHHCCEE
IGRYKARSTMRKLGLVARYPKKYQTTTDSNHNNRIEPNKLNRQFTVEEANHYWTTDITYI
EEEHHHHHHHHHHHHHHHCCCHHCCCCCCCCCCCCCCCCCCCEEEEECCCEEEECCEEEE
ATHQGFIYLAIVMDLYSRRIVGWSIADNMRTELCSNALDMAYWQRKPASGLLHHSDRGSQ
EECCCHHHHHHHHHHHHCCEEEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
YTSDDYRKLLSTMEMDVSMSGKGECWDNAPTERFFRSLKHEQLNYETFKTKKAAELSILD
CCCHHHHHHHHHHHCCEECCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHCCHHHHHHHHH
YLAYYNGKRPHSVNGYLSPIQYENKVAKKVSSFYSPLQGDPNDFVILDTTPKQVCLLQLV
HHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCHHHHHHHHHH
LK
HC
>Mature Secondary Structure
MCRVMQVSSSAFYAWENTAIKPFDTLGFNLDCTVKNTFKTHRMTLGSRRMVTELAKQNIV
CCEEEEECCCEEEEECCCCCCCHHHCCCCEEEEECCCHHHHHHHCCCHHHHHHHHHCCEE
IGRYKARSTMRKLGLVARYPKKYQTTTDSNHNNRIEPNKLNRQFTVEEANHYWTTDITYI
EEEHHHHHHHHHHHHHHHCCCHHCCCCCCCCCCCCCCCCCCCEEEEECCCEEEECCEEEE
ATHQGFIYLAIVMDLYSRRIVGWSIADNMRTELCSNALDMAYWQRKPASGLLHHSDRGSQ
EECCCHHHHHHHHHHHHCCEEEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
YTSDDYRKLLSTMEMDVSMSGKGECWDNAPTERFFRSLKHEQLNYETFKTKKAAELSILD
CCCHHHHHHHHHHHCCEECCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHCCHHHHHHHHH
YLAYYNGKRPHSVNGYLSPIQYENKVAKKVSSFYSPLQGDPNDFVILDTTPKQVCLLQLV
HHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCHHHHHHHHHH
LK
HC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2824781 [H]