Click here to switch to the map view.

The map label for this gene is engA

Identifier: 119944927

GI number: 119944927

Start: 1463082

End: 1464551

Strand: Direct

Name: engA

Synonym: Ping_1172

Alternate gene names: 119944927

Gene position: 1463082-1464551 (Clockwise)

Preceding gene: 119944926

Following gene: 119944928

Centisome position: 32.09

GC content: 42.38

Gene sequence:

>1470_bases
ATGTTACCAGTTGTCGCTTTAGTCGGCCGCCCAAATGTGGGTAAATCAACTTTGTTTAACCGCTTAACTCGTACTCGTGA
TGCATTAGTCGCGGATTTTCCAGGTTTAACGCGAGATCGTAAATACGGTCAGGCGAAAATCGATGAACACGAATTTATCG
TTATTGATACAGGCGGTATTACCGGTGATGAAGAGGGTATTGATGCTTTAATGGCAGGTCAGTCTTTACTGGCCATTGAT
GAAGCCGATGCGGTTTTGTTTTTAGTTGATGCACGTGCCGGTATGACCATTGCAGATGAAGCCATCGCAGATCACCTGCG
TAAACAAGATAAAAAAGTCTTTGTTGTTGCTAACAAAACAGATGGTGTTGATGCCGATTCTGTTTGTGCCGAGTTTTATG
CGCTTGGACTTGGCGAGGTTTATCATATCGCGGCTGCACAGGGTAAAGGTGTGCGCCAGATGATTGAGATCGCCTTAGAT
GGTTTCTTCGATGATGTCGAGCAGGAAGATGACTTTTCTGATCTGGAAACTGGTCTTGAATTTGTTGAAGAAGATGAAGC
TTTATTACTAAAAGAGCAGGAACGCCTGGCCGCTTTACCTATTAAATTGGCTCTAATAGGCCGTCCTAATGTGGGCAAGT
CTACGCTTACCAATCGAATTTTAGGCGAAGAACGTGTTCTTGTGTACGATCTGCCCGGAACAACACGTGATAGTATTTAT
ATTCCCATGAGCCGTGATGATCGGGAATATATTCTTATTGATACTGCCGGTGTGCGCAAGCGTAAAAAAGTAAACGAAAC
CGTTGAAAAATTCTCTGTTATTAAAACATTACAAGCGATTGAAGACTGTAACGTTGTGCTCTTGATTATTGATGCACGAG
ATGGTATTTCGGATCAGGATTTAAGTTTGTTAGGTTTTACCCTGAATGCGGGACGTTCATTAGTCATTGCTGTCAATAAA
TGGGATGGCATGACCGAATACGACAAAGAGCGGGTTAAAAGTGAACTGGATCGCCGTTTAGGTTTTATCGATTTTGCAAA
AATTCATTTTATCTCTGCGCTGCACGGAACGGGTGTCGGCCATTTATATGAATCTGTTGAAGAAGCCTATGACTCTTCGA
CAAAACGTATCTCTACGTCAATTTTAACGCGTATTATGACCATGGCGGCAGCTGATCACGAGCCTCCTATGGTAGGTAGT
CGTCGTGTTAAATTACGTTATGCCCATGCAGGGGGCTATAATCCGCCACTGATTGTTATTCATGGTAATCAAGTGAAAAA
ATTAGCGGATTCTTACAAACGTTATTTGATGAATTACTTCCGCCGCTCACTGGGTATTATGGGCACACCGATTCGTATTG
AATTCCGTGAAGGTACTAACCCGTTTGCAGGGCGTCGTAATAAATTGACACCAAATCAGATGTATAAACGTCAACGTCTG
GTGAAGTTTCATAAAAAAAGTAAAAAATAA

Upstream 100 bases:

>100_bases
CATCGATAAATGTAGAATAATTCCTTACATTTTTACTGTATACTTACAGCCCCTCGTATTTATTGCGGAGGGGCTTTTTT
TTGTTTGATAGGATTGAAAT

Downstream 100 bases:

>100_bases
TGGCATTAAAATGCCCTAAATGTGCTTATGAAATAGAGTCTAAGGGCATACAGAAACAACATTATTATTGTGATGCTTGC
GACAGTGACTTAAAACTTCA

Product: GTP-binding protein EngA

Products: NA

Alternate protein names: GTP-binding protein EngA

Number of amino acids: Translated: 489; Mature: 489

Protein sequence:

>489_residues
MLPVVALVGRPNVGKSTLFNRLTRTRDALVADFPGLTRDRKYGQAKIDEHEFIVIDTGGITGDEEGIDALMAGQSLLAID
EADAVLFLVDARAGMTIADEAIADHLRKQDKKVFVVANKTDGVDADSVCAEFYALGLGEVYHIAAAQGKGVRQMIEIALD
GFFDDVEQEDDFSDLETGLEFVEEDEALLLKEQERLAALPIKLALIGRPNVGKSTLTNRILGEERVLVYDLPGTTRDSIY
IPMSRDDREYILIDTAGVRKRKKVNETVEKFSVIKTLQAIEDCNVVLLIIDARDGISDQDLSLLGFTLNAGRSLVIAVNK
WDGMTEYDKERVKSELDRRLGFIDFAKIHFISALHGTGVGHLYESVEEAYDSSTKRISTSILTRIMTMAAADHEPPMVGS
RRVKLRYAHAGGYNPPLIVIHGNQVKKLADSYKRYLMNYFRRSLGIMGTPIRIEFREGTNPFAGRRNKLTPNQMYKRQRL
VKFHKKSKK

Sequences:

>Translated_489_residues
MLPVVALVGRPNVGKSTLFNRLTRTRDALVADFPGLTRDRKYGQAKIDEHEFIVIDTGGITGDEEGIDALMAGQSLLAID
EADAVLFLVDARAGMTIADEAIADHLRKQDKKVFVVANKTDGVDADSVCAEFYALGLGEVYHIAAAQGKGVRQMIEIALD
GFFDDVEQEDDFSDLETGLEFVEEDEALLLKEQERLAALPIKLALIGRPNVGKSTLTNRILGEERVLVYDLPGTTRDSIY
IPMSRDDREYILIDTAGVRKRKKVNETVEKFSVIKTLQAIEDCNVVLLIIDARDGISDQDLSLLGFTLNAGRSLVIAVNK
WDGMTEYDKERVKSELDRRLGFIDFAKIHFISALHGTGVGHLYESVEEAYDSSTKRISTSILTRIMTMAAADHEPPMVGS
RRVKLRYAHAGGYNPPLIVIHGNQVKKLADSYKRYLMNYFRRSLGIMGTPIRIEFREGTNPFAGRRNKLTPNQMYKRQRL
VKFHKKSKK
>Mature_489_residues
MLPVVALVGRPNVGKSTLFNRLTRTRDALVADFPGLTRDRKYGQAKIDEHEFIVIDTGGITGDEEGIDALMAGQSLLAID
EADAVLFLVDARAGMTIADEAIADHLRKQDKKVFVVANKTDGVDADSVCAEFYALGLGEVYHIAAAQGKGVRQMIEIALD
GFFDDVEQEDDFSDLETGLEFVEEDEALLLKEQERLAALPIKLALIGRPNVGKSTLTNRILGEERVLVYDLPGTTRDSIY
IPMSRDDREYILIDTAGVRKRKKVNETVEKFSVIKTLQAIEDCNVVLLIIDARDGISDQDLSLLGFTLNAGRSLVIAVNK
WDGMTEYDKERVKSELDRRLGFIDFAKIHFISALHGTGVGHLYESVEEAYDSSTKRISTSILTRIMTMAAADHEPPMVGS
RRVKLRYAHAGGYNPPLIVIHGNQVKKLADSYKRYLMNYFRRSLGIMGTPIRIEFREGTNPFAGRRNKLTPNQMYKRQRL
VKFHKKSKK

Specific function: GTPase that plays an essential role in the late steps of ribosome biogenesis

COG id: COG1160

COG function: function code R; Predicted GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH-like domain

Homologues:

Organism=Escherichia coli, GI87082120, Length=490, Percent_Identity=70, Blast_Score=701, Evalue=0.0,
Organism=Escherichia coli, GI2367268, Length=149, Percent_Identity=32.2147651006711, Blast_Score=65, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6323665, Length=254, Percent_Identity=26.3779527559055, Blast_Score=80, Evalue=8e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DER_PSYIN (A1SU43)

Other databases:

- EMBL:   CP000510
- RefSeq:   YP_942607.1
- ProteinModelPortal:   A1SU43
- SMR:   A1SU43
- STRING:   A1SU43
- GeneID:   4624470
- GenomeReviews:   CP000510_GR
- KEGG:   pin:Ping_1172
- eggNOG:   COG1160
- HOGENOM:   HBG592135
- OMA:   KCEKAFD
- PhylomeDB:   A1SU43
- ProtClustDB:   PRK00093
- BioCyc:   PING357804:PING_1172-MONOMER
- GO:   GO:0005622
- HAMAP:   MF_00195
- InterPro:   IPR003593
- InterPro:   IPR016484
- InterPro:   IPR006073
- InterPro:   IPR015946
- InterPro:   IPR002917
- InterPro:   IPR005225
- Gene3D:   G3DSA:3.30.300.20
- PIRSF:   PIRSF006485
- PRINTS:   PR00326
- SMART:   SM00382
- TIGRFAMs:   TIGR03594
- TIGRFAMs:   TIGR00231

Pfam domain/function: PF01926 MMR_HSR1

EC number: NA

Molecular weight: Translated: 54655; Mature: 54655

Theoretical pI: Translated: 6.69; Mature: 6.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLPVVALVGRPNVGKSTLFNRLTRTRDALVADFPGLTRDRKYGQAKIDEHEFIVIDTGGI
CCCEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEECCCC
TGDEEGIDALMAGQSLLAIDEADAVLFLVDARAGMTIADEAIADHLRKQDKKVFVVANKT
CCCHHHHHHHHCCCEEEEEECCCEEEEEEECCCCCEEHHHHHHHHHHHCCCEEEEEECCC
DGVDADSVCAEFYALGLGEVYHIAAAQGKGVRQMIEIALDGFFDDVEQEDDFSDLETGLE
CCCCHHHHHHHHHHHCCCHHEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
FVEEDEALLLKEQERLAALPIKLALIGRPNVGKSTLTNRILGEERVLVYDLPGTTRDSIY
HHCCCCHHHHHHHHHHHHCCEEEEEECCCCCCHHHHHHHHCCCCCEEEEECCCCCCCCEE
IPMSRDDREYILIDTAGVRKRKKVNETVEKFSVIKTLQAIEDCNVVLLIIDARDGISDQD
EECCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCC
LSLLGFTLNAGRSLVIAVNKWDGMTEYDKERVKSELDRRLGFIDFAKIHFISALHGTGVG
CEEEEEEECCCCEEEEEEECCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCHH
HLYESVEEAYDSSTKRISTSILTRIMTMAAADHEPPMVGSRRVKLRYAHAGGYNPPLIVI
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEECCCCCCCEEEE
HGNQVKKLADSYKRYLMNYFRRSLGIMGTPIRIEFREGTNPFAGRRNKLTPNQMYKRQRL
ECCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHH
VKFHKKSKK
HHHHHHCCC
>Mature Secondary Structure
MLPVVALVGRPNVGKSTLFNRLTRTRDALVADFPGLTRDRKYGQAKIDEHEFIVIDTGGI
CCCEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEECCCC
TGDEEGIDALMAGQSLLAIDEADAVLFLVDARAGMTIADEAIADHLRKQDKKVFVVANKT
CCCHHHHHHHHCCCEEEEEECCCEEEEEEECCCCCEEHHHHHHHHHHHCCCEEEEEECCC
DGVDADSVCAEFYALGLGEVYHIAAAQGKGVRQMIEIALDGFFDDVEQEDDFSDLETGLE
CCCCHHHHHHHHHHHCCCHHEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
FVEEDEALLLKEQERLAALPIKLALIGRPNVGKSTLTNRILGEERVLVYDLPGTTRDSIY
HHCCCCHHHHHHHHHHHHCCEEEEEECCCCCCHHHHHHHHCCCCCEEEEECCCCCCCCEE
IPMSRDDREYILIDTAGVRKRKKVNETVEKFSVIKTLQAIEDCNVVLLIIDARDGISDQD
EECCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCC
LSLLGFTLNAGRSLVIAVNKWDGMTEYDKERVKSELDRRLGFIDFAKIHFISALHGTGVG
CEEEEEEECCCCEEEEEEECCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCHH
HLYESVEEAYDSSTKRISTSILTRIMTMAAADHEPPMVGSRRVKLRYAHAGGYNPPLIVI
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEECCCCCCCEEEE
HGNQVKKLADSYKRYLMNYFRRSLGIMGTPIRIEFREGTNPFAGRRNKLTPNQMYKRQRL
ECCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHH
VKFHKKSKK
HHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA