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The map label for this gene is fabD [H]

Identifier: 119944846

GI number: 119944846

Start: 1358934

End: 1359875

Strand: Direct

Name: fabD [H]

Synonym: Ping_1088

Alternate gene names: 119944846

Gene position: 1358934-1359875 (Clockwise)

Preceding gene: 119944845

Following gene: 119944847

Centisome position: 29.8

GC content: 42.99

Gene sequence:

>942_bases
ATGACAAACTTTACATTTGCTTTCCCCGGTCAAGGCTCTCAACATGTTGGCATGTTGGCCGAGCTTGCACAATCTTGCCC
CGTTGTGGTTGAAACGTTTAAACAAGCAAGTGATGTGCTAGGTTACGATCTTTGGGATCTTGTTCAACAAGGCCCTGCGG
AAATATTAAACCAAACAGATAAAACACAACCCGCTTTATTAACAGCTTCCGTTGCACTTTGGCGCGTTTGGGCTGAGCAG
AAGGGTCCAACACCTTCTGTTATTGCAGGACATAGTTTGGGTGAATACTCAGCATTAGTCTGTGCCGGAGTGATTGAATT
TAAAGATGCCGTTAAATTGGTTGAATTACGCGGGCAGCTAATGCAGCAAGCTGTTCCAGCAGGCACTGGGGCAATGTCTG
CCATTATTGGTTTAGATAATAATAAAATTGCCGAATGTTGTGTACAAGCTGCCGAGGGACAAATTGTGTCGCCGGTTAAC
TTTAATTCACCGGGCCAGGTGGTTATTGCGGGTAATAAAGAAGCGGTTGAGCGTGCTGGAATCCTATTAAAAGAAGCCGG
TGCAAAACGTGTATTGCCTTTACCCGTGAGTGTGCCATCACATTGTGCCTTGATGAAACCTGCTGCGGAAAAATTGGCCG
TTGCATTACAATCGATTCATTTTAATACTCCAAACATTGCTGTGATTAATAATGTTGATGTGGTTGCCGAAAGTGATGTT
GAAAAAATTAAAGATGCGCTTGTCCGCCAATTATTTTGTCCGGTGCGTTGGAGTGATATTGTTGAAAAAATGGCATCCGA
TGGCATTACAATACAAGTTGAAGCTGGCCCTGGTAAAGTATTAAGTGGTTTAGTTCGTCGTATTAATAAAAGTCTAACTG
CGCAAGTTATTAACGATAATGCGACGCTTGAAAAAGCATTAGCTGCGGTTAAAGGAGAATAA

Upstream 100 bases:

>100_bases
TTAATCTTATTAGAAGCATTTGGCGGCGGATTTACCTGGGGCTCAGCGCTAGTGCGCATGTGAATAAATAAAAATCAATC
AATATCTGGAAATATAAAAA

Downstream 100 bases:

>100_bases
AGATGAGCATGGAAGATAAAGTTGTATTAGTGACGGGCGCGAGTCGTGGTATTGGCCGCGCAATTGCAGAGCACTTTGCT
GCATTAGGTGCGACTGTTTT

Product: malonyl CoA-acyl carrier protein transacylase

Products: NA

Alternate protein names: MCT [H]

Number of amino acids: Translated: 313; Mature: 312

Protein sequence:

>313_residues
MTNFTFAFPGQGSQHVGMLAELAQSCPVVVETFKQASDVLGYDLWDLVQQGPAEILNQTDKTQPALLTASVALWRVWAEQ
KGPTPSVIAGHSLGEYSALVCAGVIEFKDAVKLVELRGQLMQQAVPAGTGAMSAIIGLDNNKIAECCVQAAEGQIVSPVN
FNSPGQVVIAGNKEAVERAGILLKEAGAKRVLPLPVSVPSHCALMKPAAEKLAVALQSIHFNTPNIAVINNVDVVAESDV
EKIKDALVRQLFCPVRWSDIVEKMASDGITIQVEAGPGKVLSGLVRRINKSLTAQVINDNATLEKALAAVKGE

Sequences:

>Translated_313_residues
MTNFTFAFPGQGSQHVGMLAELAQSCPVVVETFKQASDVLGYDLWDLVQQGPAEILNQTDKTQPALLTASVALWRVWAEQ
KGPTPSVIAGHSLGEYSALVCAGVIEFKDAVKLVELRGQLMQQAVPAGTGAMSAIIGLDNNKIAECCVQAAEGQIVSPVN
FNSPGQVVIAGNKEAVERAGILLKEAGAKRVLPLPVSVPSHCALMKPAAEKLAVALQSIHFNTPNIAVINNVDVVAESDV
EKIKDALVRQLFCPVRWSDIVEKMASDGITIQVEAGPGKVLSGLVRRINKSLTAQVINDNATLEKALAAVKGE
>Mature_312_residues
TNFTFAFPGQGSQHVGMLAELAQSCPVVVETFKQASDVLGYDLWDLVQQGPAEILNQTDKTQPALLTASVALWRVWAEQK
GPTPSVIAGHSLGEYSALVCAGVIEFKDAVKLVELRGQLMQQAVPAGTGAMSAIIGLDNNKIAECCVQAAEGQIVSPVNF
NSPGQVVIAGNKEAVERAGILLKEAGAKRVLPLPVSVPSHCALMKPAAEKLAVALQSIHFNTPNIAVINNVDVVAESDVE
KIKDALVRQLFCPVRWSDIVEKMASDGITIQVEAGPGKVLSGLVRRINKSLTAQVINDNATLEKALAAVKGE

Specific function: Fatty acid biosynthesis. [C]

COG id: COG0331

COG function: function code I; (acyl-carrier-protein) S-malonyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabD family [H]

Homologues:

Organism=Homo sapiens, GI51243059, Length=300, Percent_Identity=35, Blast_Score=146, Evalue=3e-35,
Organism=Homo sapiens, GI27477045, Length=108, Percent_Identity=45.3703703703704, Blast_Score=74, Evalue=2e-13,
Organism=Escherichia coli, GI1787334, Length=307, Percent_Identity=67.1009771986971, Blast_Score=403, Evalue=1e-114,
Organism=Caenorhabditis elegans, GI71984332, Length=293, Percent_Identity=31.0580204778157, Blast_Score=112, Evalue=3e-25,
Organism=Caenorhabditis elegans, GI17550940, Length=288, Percent_Identity=28.4722222222222, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24665753, Length=300, Percent_Identity=33, Blast_Score=137, Evalue=9e-33,

Paralogues:

None

Copy number: 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001227
- InterPro:   IPR014043
- InterPro:   IPR016035
- InterPro:   IPR004410
- InterPro:   IPR016036 [H]

Pfam domain/function: PF00698 Acyl_transf_1 [H]

EC number: =2.3.1.39 [H]

Molecular weight: Translated: 33121; Mature: 32989

Theoretical pI: Translated: 5.40; Mature: 5.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNFTFAFPGQGSQHVGMLAELAQSCPVVVETFKQASDVLGYDLWDLVQQGPAEILNQTD
CCCEEEECCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHCCHHHHHHHCCHHHHHCCCC
KTQPALLTASVALWRVWAEQKGPTPSVIAGHSLGEYSALVCAGVIEFKDAVKLVELRGQL
CCCCHHHHHHHHHHHHHHHCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
MQQAVPAGTGAMSAIIGLDNNKIAECCVQAAEGQIVSPVNFNSPGQVVIAGNKEAVERAG
HHHHCCCCCCHHHHEEECCCCHHHHHHHHHHCCCEECCCCCCCCCCEEEECCHHHHHHHH
ILLKEAGAKRVLPLPVSVPSHCALMKPAAEKLAVALQSIHFNTPNIAVINNVDVVAESDV
HHHHHCCCCCEEECCCCCCCCHHHHCHHHHHHHHHHHHHCCCCCCEEEEECCCEEECCHH
EKIKDALVRQLFCPVRWSDIVEKMASDGITIQVEAGPGKVLSGLVRRINKSLTAQVINDN
HHHHHHHHHHHHCCCCHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHCCC
ATLEKALAAVKGE
HHHHHHHHHHCCC
>Mature Secondary Structure 
TNFTFAFPGQGSQHVGMLAELAQSCPVVVETFKQASDVLGYDLWDLVQQGPAEILNQTD
CCEEEECCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHCCHHHHHHHCCHHHHHCCCC
KTQPALLTASVALWRVWAEQKGPTPSVIAGHSLGEYSALVCAGVIEFKDAVKLVELRGQL
CCCCHHHHHHHHHHHHHHHCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
MQQAVPAGTGAMSAIIGLDNNKIAECCVQAAEGQIVSPVNFNSPGQVVIAGNKEAVERAG
HHHHCCCCCCHHHHEEECCCCHHHHHHHHHHCCCEECCCCCCCCCCEEEECCHHHHHHHH
ILLKEAGAKRVLPLPVSVPSHCALMKPAAEKLAVALQSIHFNTPNIAVINNVDVVAESDV
HHHHHCCCCCEEECCCCCCCCHHHHCHHHHHHHHHHHHHCCCCCCEEEEECCCEEECCHH
EKIKDALVRQLFCPVRWSDIVEKMASDGITIQVEAGPGKVLSGLVRRINKSLTAQVINDN
HHHHHHHHHHHHCCCCHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHCCC
ATLEKALAAVKGE
HHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]