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The map label for this gene is cfa [H]

Identifier: 119944761

GI number: 119944761

Start: 1259504

End: 1260745

Strand: Direct

Name: cfa [H]

Synonym: Ping_1003

Alternate gene names: 119944761

Gene position: 1259504-1260745 (Clockwise)

Preceding gene: 119944760

Following gene: 119944762

Centisome position: 27.62

GC content: 39.53

Gene sequence:

>1242_bases
ATGGCCGTTAATACAACAAAACTAAATACAGATATTGAAGCAATGGCTTATATAGATCAGTTTGCTAAAAAGGTATTGGT
ATCGATATTAGGAAAAATGCAGCAGGCCTGTTTGATTTTAGTCGATCAGCAACAGGAAATTATTTTAGGGGATCCTAACG
CAAGCTTAAAAGGCAAAATTGTTATAAAAAACAGTAAAACCTATCGGAAAATTTTGTTGGGCGGAAGCGTTGCTGCAGGG
GAGTCTTATATTCAAGGCTGGTGGAGCAGCCCGGACTTGACTAAGGTTATTCAAGTATTAGGACGTGAACAGGGGGTACA
GGACGAAATTGAAAAACGTCTTGCAAAAGTGATGGCGATTCCCACTTGGATTTATCATAAGGCCCGCAAAAATACCCGTA
GCGGCTCAAAAAAGAATATTCTTGCACATTATGACCTTGGCAATGATCTTTATGAGCAATTTTTAGATAAAGAGATGCTT
TACTCAAGCGCAATTTATCCAACCTCAGATGCCAGTTTAGAAGAAGCCCAGCTGCATAAATTAAAAACTATTTGTGACAG
ACTTGCGTTAAAAAAAGGCGAAACATTACTGGAAATAGGAACCGGCTGGGGTGCCCTGGCCATTTATGCAGCACAGCATT
ATGGCGTAAAAGTCACTACTACTACTATTTCAGAAGAACAGTTTTTATACACACAAGCACGTGTCAAAAGCTTGGGATTA
GAAGGCAGTATTACATTATTAAAATCCGATTATCGAGATCTGACCGGACAGTACGATAAGTTAGTGTCAATCGAAATGAT
TGAAGCTGTTGGCCATGAATACCTGGCGAGTTTTTTCGAAATCTGTAATAACCACCTGAAACCGCATGGAAAAATGTTGA
TTCAAGCTATTACTATTGCGGATCAGCGTTATGACCAATACCGCTCTAGTGTGGACTTTATTCAGCGTTATATTTTTCCT
GGTGGCTGCTTGCCCTCGATCAGTGTAATGGCCAATAATATCAACAATAAAACCGATATGGTAATCACTTCATTGCATGA
CATTGGCATGGATTATGCCCAAACATTAAACCACTGGCGTGAGCAGTTTGAGATTTCTCTCCTTGAAATAAAAAAATTGG
GATATAACGATGATTTTATTCGTTTATGGCGTTTTTATTTCTGTTATTGCGAAGGTGCCTTCCTGGAAAGAAATATCAGT
GCGGTGCATCTGATTGCCGCTAAACCCGCTTTTAGAGCCTGA

Upstream 100 bases:

>100_bases
ATGACCCTAAAAACCTTGGCCGGTATTTATTGGCAAGCTTTAAAACTGTTTATTAAAGGTGTGCCTTTTATTGGTCACGC
TGTAAAAAAGGAAATTGATA

Downstream 100 bases:

>100_bases
GGTTTTTAATATGCGGTGCTTTATTAGAAAACACTTTTACTGGTTTAATTTTATTTGGTTCCAGTTAATGTGGTTTATTG
CTGTTTTTTTTACGGTCAGC

Product: cyclopropane-fatty-acyl-phospholipid synthase

Products: NA

Alternate protein names: CFA synthase; Cyclopropane fatty acid synthase [H]

Number of amino acids: Translated: 413; Mature: 412

Protein sequence:

>413_residues
MAVNTTKLNTDIEAMAYIDQFAKKVLVSILGKMQQACLILVDQQQEIILGDPNASLKGKIVIKNSKTYRKILLGGSVAAG
ESYIQGWWSSPDLTKVIQVLGREQGVQDEIEKRLAKVMAIPTWIYHKARKNTRSGSKKNILAHYDLGNDLYEQFLDKEML
YSSAIYPTSDASLEEAQLHKLKTICDRLALKKGETLLEIGTGWGALAIYAAQHYGVKVTTTTISEEQFLYTQARVKSLGL
EGSITLLKSDYRDLTGQYDKLVSIEMIEAVGHEYLASFFEICNNHLKPHGKMLIQAITIADQRYDQYRSSVDFIQRYIFP
GGCLPSISVMANNINNKTDMVITSLHDIGMDYAQTLNHWREQFEISLLEIKKLGYNDDFIRLWRFYFCYCEGAFLERNIS
AVHLIAAKPAFRA

Sequences:

>Translated_413_residues
MAVNTTKLNTDIEAMAYIDQFAKKVLVSILGKMQQACLILVDQQQEIILGDPNASLKGKIVIKNSKTYRKILLGGSVAAG
ESYIQGWWSSPDLTKVIQVLGREQGVQDEIEKRLAKVMAIPTWIYHKARKNTRSGSKKNILAHYDLGNDLYEQFLDKEML
YSSAIYPTSDASLEEAQLHKLKTICDRLALKKGETLLEIGTGWGALAIYAAQHYGVKVTTTTISEEQFLYTQARVKSLGL
EGSITLLKSDYRDLTGQYDKLVSIEMIEAVGHEYLASFFEICNNHLKPHGKMLIQAITIADQRYDQYRSSVDFIQRYIFP
GGCLPSISVMANNINNKTDMVITSLHDIGMDYAQTLNHWREQFEISLLEIKKLGYNDDFIRLWRFYFCYCEGAFLERNIS
AVHLIAAKPAFRA
>Mature_412_residues
AVNTTKLNTDIEAMAYIDQFAKKVLVSILGKMQQACLILVDQQQEIILGDPNASLKGKIVIKNSKTYRKILLGGSVAAGE
SYIQGWWSSPDLTKVIQVLGREQGVQDEIEKRLAKVMAIPTWIYHKARKNTRSGSKKNILAHYDLGNDLYEQFLDKEMLY
SSAIYPTSDASLEEAQLHKLKTICDRLALKKGETLLEIGTGWGALAIYAAQHYGVKVTTTTISEEQFLYTQARVKSLGLE
GSITLLKSDYRDLTGQYDKLVSIEMIEAVGHEYLASFFEICNNHLKPHGKMLIQAITIADQRYDQYRSSVDFIQRYIFPG
GCLPSISVMANNINNKTDMVITSLHDIGMDYAQTLNHWREQFEISLLEIKKLGYNDDFIRLWRFYFCYCEGAFLERNISA
VHLIAAKPAFRA

Specific function: Transfers a methylene group from S-adenosyl-L-methionine to the cis double bond of an unsaturated fatty acid chain resulting in the replacement of the double bond with a methylene bridge [H]

COG id: COG2230

COG function: function code M; Cyclopropane fatty acid synthase and related methyltransferases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CFA/CMAS family [H]

Homologues:

Organism=Escherichia coli, GI1787951, Length=360, Percent_Identity=36.6666666666667, Blast_Score=215, Evalue=5e-57,
Organism=Caenorhabditis elegans, GI133904226, Length=371, Percent_Identity=40.1617250673854, Blast_Score=243, Evalue=1e-64,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003333 [H]

Pfam domain/function: PF02353 CMAS [H]

EC number: =2.1.1.79 [H]

Molecular weight: Translated: 46783; Mature: 46651

Theoretical pI: Translated: 7.86; Mature: 7.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVNTTKLNTDIEAMAYIDQFAKKVLVSILGKMQQACLILVDQQQEIILGDPNASLKGKI
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCEEEEECCCCCCEEEE
VIKNSKTYRKILLGGSVAAGESYIQGWWSSPDLTKVIQVLGREQGVQDEIEKRLAKVMAI
EEECCCHHHHHEECCCCCCCHHHHHCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHH
PTWIYHKARKNTRSGSKKNILAHYDLGNDLYEQFLDKEMLYSSAIYPTSDASLEEAQLHK
HHHHHHHHHCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHH
LKTICDRLALKKGETLLEIGTGWGALAIYAAQHYGVKVTTTTISEEQFLYTQARVKSLGL
HHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHCCEEEEEEEECCHHHHHHHHHHHHCCC
EGSITLLKSDYRDLTGQYDKLVSIEMIEAVGHEYLASFFEICNNHLKPHGKMLIQAITIA
CCCEEEEHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
DQRYDQYRSSVDFIQRYIFPGGCLPSISVMANNINNKTDMVITSLHDIGMDYAQTLNHWR
HHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCHHHEEHHHHHHCCHHHHHHHHHH
EQFEISLLEIKKLGYNDDFIRLWRFYFCYCEGAFLERNISAVHLIAAKPAFRA
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCHHHHCCCCEEEEEECCCCCCC
>Mature Secondary Structure 
AVNTTKLNTDIEAMAYIDQFAKKVLVSILGKMQQACLILVDQQQEIILGDPNASLKGKI
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCEEEEECCCCCCEEEE
VIKNSKTYRKILLGGSVAAGESYIQGWWSSPDLTKVIQVLGREQGVQDEIEKRLAKVMAI
EEECCCHHHHHEECCCCCCCHHHHHCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHH
PTWIYHKARKNTRSGSKKNILAHYDLGNDLYEQFLDKEMLYSSAIYPTSDASLEEAQLHK
HHHHHHHHHCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHH
LKTICDRLALKKGETLLEIGTGWGALAIYAAQHYGVKVTTTTISEEQFLYTQARVKSLGL
HHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHCCEEEEEEEECCHHHHHHHHHHHHCCC
EGSITLLKSDYRDLTGQYDKLVSIEMIEAVGHEYLASFFEICNNHLKPHGKMLIQAITIA
CCCEEEEHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
DQRYDQYRSSVDFIQRYIFPGGCLPSISVMANNINNKTDMVITSLHDIGMDYAQTLNHWR
HHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCHHHEEHHHHHHCCHHHHHHHHHH
EQFEISLLEIKKLGYNDDFIRLWRFYFCYCEGAFLERNISAVHLIAAKPAFRA
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCHHHHCCCCEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]