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The map label for this gene is htpG

Identifier: 119944716

GI number: 119944716

Start: 1200629

End: 1202533

Strand: Direct

Name: htpG

Synonym: Ping_0956

Alternate gene names: 119944716

Gene position: 1200629-1202533 (Clockwise)

Preceding gene: 119944715

Following gene: 119944717

Centisome position: 26.33

GC content: 37.85

Gene sequence:

>1905_bases
ATGGAACATCAACAAAATCATACTTTTAGCGCGGATACCGGCAAACTTCTTAAGTTAATGATTCATTCTTTATATTCCAA
TAAAGAAATATTCTTACGTGAACTTGTCTCTAATGCAGCAGATGCTGCCGATAAGTTACGTTTTAAAGCACTTTCTGACG
GTTCTTTATTTGAAAATGATGGTGACTTACGTGTTCGTTTGAGCTTTGATGCAGATCTTAAAACTATTACTATTAGTGAT
AATGGTATCGGTATGAGCCGAGATGAAGTTATCGAACACTTAGGTACTATTGCAAAATCAGGTACCAGTGATTTCTTTGA
GCAACTTTCTGGTGATCAAGTTAAAGATTCGCAACTTATAGGTCAGTTTGGTGTTGGTTTTTATTCTTCATTTATTGTTG
CAGACAAAGTCACTGTTAATACGCGTAAAGCGGGCGAGCCAGCTTCTCAAGGTACCTGCTGGATTTCTACTGGCGAGTCA
GATTACACCGTTGCTGATATAGAAAAAGCGGGTCGTGGTACTGAAATAACGCTTCACCTTCGAGATGATGAAACTGAATT
TTTAAATGACTACAAATTACGTGGTATTGTTTCTAAATATTCTGATCACATCAGTATTCCTGTTGAAATGTTCAAAGAAG
CAACTGAAGAGTCTGAAGGTTCTGATGGCGAAAAAGTTCCTGCGACAGAAGCAACTTGGGAAGCCGTCAATAAAGCGACA
GCACTTTGGAGTTGCTCTAAGAGCGAACTTAAAGATGAAGAATATAAAGAGTTTTATAAACATATTGCTAATGACTTTGA
AGATCCTCTAACATGGAGCCACAACAAAGTTGAAGGTGAGCAAGCCTATACAAGCTTACTTTATATCCCTAAACGTGCTC
CTTATGATCTTTGGAACCGTGAAAAAGCGCATGGTCTAAAACTGTATGTTCAACGTGTCTTTGTTATGGATGATGCAGAG
CAGTTCATGCCAACTTACTTACGTTTTGTAAAAGGTGTGCTTGACTCAAACGACCTACCATTAAATGTTTCTCGTGAAAT
CTTACAAGATACACGTGTTACCGCCAAGTTACGCAGCGGATGTACTAAACGTGTTCTTGATTTGCTTACCAAGCTTGCTA
AAAAAGATGATGACGCATACAACCTGTTCTGGAAAGAGTTTGGTCAAGTATTAAAAGAAGGTCCTGCTGAAGATTCATCA
AACAAAGAAAAAATCGGCAAGCTATTCCGTTTCTCTTCGACTGAAACTGATTCAACTGAACAAACTGTTTCTTTAGATGC
GTATATCAGCCGTATGACTGAAGGACAAGATAAGATTTATTACATTACTGCTGATAGTTTTAATGCGGCAAAAAATAGTC
CTCACTTAGAAGTGTTACGTGAAAAAGGTATCGAAGTATTATTACTTTCAGATCGTATTGATGAATGGTTATTAAGCCAT
TTACCTGAATATGATGGCAAAACTTTTACTTCTGTTACCCAGGGAGATCTTGATTTAGGTAAGCTTGACAGTGAAGAAAA
GAAAAAAGAACAAGAAAAACAAGAAACTGAATTTGCCAGCTTTGTTGAGCGTGTAAAAGCTGTCTTAGGTGATAAAGTTA
AAGATGTACGTTTAACGCATCGCCTAACATCAACGCCTTCTTGTATCGTAGCTGACAACGATGATATGAGCACACAAATG
GCTAAATTAATGGCTCAAATGGGACAACCAGTACCAGAGAGCAAACCCGTCTTTGAACTGAATCCTGAACATGTAATGAT
TGTTAAATTAGCTGATATGGCTGATGAAGACTTATTTGCCCAGTGGTCAGAACTATTACTTGAACAAGCAATTTTATCTG
AGAAAGGCAGTTTAGATGATCCTTCTGAATTTGTTGGCCGCATCAACAAGCTGCTACTCGCTTAA

Upstream 100 bases:

>100_bases
AACATCTTGTGGACCTTGAAATCTTATCCTATGACCCCATTTTATTTTCATCGTTTATACCAAAGTCTTGTTTAGGCTAA
ATCTGAGAGAAATAGATATT

Downstream 100 bases:

>100_bases
TCCTGCTCGTTAGTTTATTTAAAAGGCCAACTTATGTTGGTCTTTTTTTTATCTAATCGAATGCTAAAGTCAAAGAATCC
TATTTTGTATATTGAACTTA

Product: heat shock protein 90

Products: NA

Alternate protein names: Heat shock protein htpG; High temperature protein G

Number of amino acids: Translated: 634; Mature: 634

Protein sequence:

>634_residues
MEHQQNHTFSADTGKLLKLMIHSLYSNKEIFLRELVSNAADAADKLRFKALSDGSLFENDGDLRVRLSFDADLKTITISD
NGIGMSRDEVIEHLGTIAKSGTSDFFEQLSGDQVKDSQLIGQFGVGFYSSFIVADKVTVNTRKAGEPASQGTCWISTGES
DYTVADIEKAGRGTEITLHLRDDETEFLNDYKLRGIVSKYSDHISIPVEMFKEATEESEGSDGEKVPATEATWEAVNKAT
ALWSCSKSELKDEEYKEFYKHIANDFEDPLTWSHNKVEGEQAYTSLLYIPKRAPYDLWNREKAHGLKLYVQRVFVMDDAE
QFMPTYLRFVKGVLDSNDLPLNVSREILQDTRVTAKLRSGCTKRVLDLLTKLAKKDDDAYNLFWKEFGQVLKEGPAEDSS
NKEKIGKLFRFSSTETDSTEQTVSLDAYISRMTEGQDKIYYITADSFNAAKNSPHLEVLREKGIEVLLLSDRIDEWLLSH
LPEYDGKTFTSVTQGDLDLGKLDSEEKKKEQEKQETEFASFVERVKAVLGDKVKDVRLTHRLTSTPSCIVADNDDMSTQM
AKLMAQMGQPVPESKPVFELNPEHVMIVKLADMADEDLFAQWSELLLEQAILSEKGSLDDPSEFVGRINKLLLA

Sequences:

>Translated_634_residues
MEHQQNHTFSADTGKLLKLMIHSLYSNKEIFLRELVSNAADAADKLRFKALSDGSLFENDGDLRVRLSFDADLKTITISD
NGIGMSRDEVIEHLGTIAKSGTSDFFEQLSGDQVKDSQLIGQFGVGFYSSFIVADKVTVNTRKAGEPASQGTCWISTGES
DYTVADIEKAGRGTEITLHLRDDETEFLNDYKLRGIVSKYSDHISIPVEMFKEATEESEGSDGEKVPATEATWEAVNKAT
ALWSCSKSELKDEEYKEFYKHIANDFEDPLTWSHNKVEGEQAYTSLLYIPKRAPYDLWNREKAHGLKLYVQRVFVMDDAE
QFMPTYLRFVKGVLDSNDLPLNVSREILQDTRVTAKLRSGCTKRVLDLLTKLAKKDDDAYNLFWKEFGQVLKEGPAEDSS
NKEKIGKLFRFSSTETDSTEQTVSLDAYISRMTEGQDKIYYITADSFNAAKNSPHLEVLREKGIEVLLLSDRIDEWLLSH
LPEYDGKTFTSVTQGDLDLGKLDSEEKKKEQEKQETEFASFVERVKAVLGDKVKDVRLTHRLTSTPSCIVADNDDMSTQM
AKLMAQMGQPVPESKPVFELNPEHVMIVKLADMADEDLFAQWSELLLEQAILSEKGSLDDPSEFVGRINKLLLA
>Mature_634_residues
MEHQQNHTFSADTGKLLKLMIHSLYSNKEIFLRELVSNAADAADKLRFKALSDGSLFENDGDLRVRLSFDADLKTITISD
NGIGMSRDEVIEHLGTIAKSGTSDFFEQLSGDQVKDSQLIGQFGVGFYSSFIVADKVTVNTRKAGEPASQGTCWISTGES
DYTVADIEKAGRGTEITLHLRDDETEFLNDYKLRGIVSKYSDHISIPVEMFKEATEESEGSDGEKVPATEATWEAVNKAT
ALWSCSKSELKDEEYKEFYKHIANDFEDPLTWSHNKVEGEQAYTSLLYIPKRAPYDLWNREKAHGLKLYVQRVFVMDDAE
QFMPTYLRFVKGVLDSNDLPLNVSREILQDTRVTAKLRSGCTKRVLDLLTKLAKKDDDAYNLFWKEFGQVLKEGPAEDSS
NKEKIGKLFRFSSTETDSTEQTVSLDAYISRMTEGQDKIYYITADSFNAAKNSPHLEVLREKGIEVLLLSDRIDEWLLSH
LPEYDGKTFTSVTQGDLDLGKLDSEEKKKEQEKQETEFASFVERVKAVLGDKVKDVRLTHRLTSTPSCIVADNDDMSTQM
AKLMAQMGQPVPESKPVFELNPEHVMIVKLADMADEDLFAQWSELLLEQAILSEKGSLDDPSEFVGRINKLLLA

Specific function: Molecular chaperone. Has ATPase activity

COG id: COG0326

COG function: function code O; Molecular chaperone, HSP90 family

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heat shock protein 90 family

Homologues:

Organism=Homo sapiens, GI20149594, Length=680, Percent_Identity=36.1764705882353, Blast_Score=410, Evalue=1e-114,
Organism=Homo sapiens, GI4507677, Length=686, Percent_Identity=36.734693877551, Blast_Score=408, Evalue=1e-114,
Organism=Homo sapiens, GI155722983, Length=645, Percent_Identity=34.8837209302326, Blast_Score=372, Evalue=1e-103,
Organism=Homo sapiens, GI154146191, Length=412, Percent_Identity=37.621359223301, Blast_Score=268, Evalue=9e-72,
Organism=Homo sapiens, GI153792590, Length=412, Percent_Identity=38.1067961165049, Blast_Score=266, Evalue=4e-71,
Organism=Escherichia coli, GI1786679, Length=636, Percent_Identity=65.4088050314465, Blast_Score=860, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17559162, Length=673, Percent_Identity=36.1069836552749, Blast_Score=424, Evalue=1e-119,
Organism=Caenorhabditis elegans, GI17542208, Length=672, Percent_Identity=36.3095238095238, Blast_Score=400, Evalue=1e-112,
Organism=Caenorhabditis elegans, GI115535205, Length=648, Percent_Identity=32.5617283950617, Blast_Score=320, Evalue=2e-87,
Organism=Caenorhabditis elegans, GI115535167, Length=449, Percent_Identity=35.4120267260579, Blast_Score=258, Evalue=9e-69,
Organism=Saccharomyces cerevisiae, GI6323840, Length=678, Percent_Identity=36.7256637168142, Blast_Score=435, Evalue=1e-122,
Organism=Saccharomyces cerevisiae, GI6325016, Length=682, Percent_Identity=36.6568914956012, Blast_Score=434, Evalue=1e-122,
Organism=Drosophila melanogaster, GI17647529, Length=687, Percent_Identity=36.6812227074236, Blast_Score=439, Evalue=1e-123,
Organism=Drosophila melanogaster, GI21357739, Length=684, Percent_Identity=35.0877192982456, Blast_Score=391, Evalue=1e-109,
Organism=Drosophila melanogaster, GI24586016, Length=659, Percent_Identity=32.9286798179059, Blast_Score=347, Evalue=2e-95,

Paralogues:

None

Copy number: 640 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 2419 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): HTPG_PSYIN (A1STI2)

Other databases:

- EMBL:   CP000510
- RefSeq:   YP_942396.1
- ProteinModelPortal:   A1STI2
- SMR:   A1STI2
- STRING:   A1STI2
- GeneID:   4626668
- GenomeReviews:   CP000510_GR
- KEGG:   pin:Ping_0956
- eggNOG:   COG0326
- HOGENOM:   HBG631012
- OMA:   AIYYITA
- PhylomeDB:   A1STI2
- ProtClustDB:   PRK05218
- BioCyc:   PING357804:PING_0956-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00505
- InterPro:   IPR003594
- InterPro:   IPR019805
- InterPro:   IPR001404
- InterPro:   IPR020575
- InterPro:   IPR020568
- Gene3D:   G3DSA:3.30.565.10
- PANTHER:   PTHR11528
- PIRSF:   PIRSF002583
- PRINTS:   PR00775
- SMART:   SM00387

Pfam domain/function: PF02518 HATPase_c; PF00183 HSP90; SSF55874 ATP_bd_ATPase; SSF54211 Ribosomal_S5_D2-typ_fold

EC number: NA

Molecular weight: Translated: 71502; Mature: 71502

Theoretical pI: Translated: 4.60; Mature: 4.60

Prosite motif: PS00298 HSP90

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEHQQNHTFSADTGKLLKLMIHSLYSNKEIFLRELVSNAADAADKLRFKALSDGSLFEND
CCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHEECCCCCCEECC
GDLRVRLSFDADLKTITISDNGIGMSRDEVIEHLGTIAKSGTSDFFEQLSGDQVKDSQLI
CCEEEEEEECCCEEEEEEECCCCCCCHHHHHHHHHHHHCCCHHHHHHHHCCCCCHHHHHH
GQFGVGFYSSFIVADKVTVNTRKAGEPASQGTCWISTGESDYTVADIEKAGRGTEITLHL
HHHHHHHHHHHHHCCEEEECCCCCCCCCCCCEEEEECCCCCCEEHHHHHCCCCCEEEEEE
RDDETEFLNDYKLRGIVSKYSDHISIPVEMFKEATEESEGSDGEKVPATEATWEAVNKAT
CCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHH
ALWSCSKSELKDEEYKEFYKHIANDFEDPLTWSHNKVEGEQAYTSLLYIPKRAPYDLWNR
HHHCCCHHHCCHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHEEECCCCCCCCCCC
EKAHGLKLYVQRVFVMDDAEQFMPTYLRFVKGVLDSNDLPLNVSREILQDTRVTAKLRSG
CHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCC
CTKRVLDLLTKLAKKDDDAYNLFWKEFGQVLKEGPAEDSSNKEKIGKLFRFSSTETDSTE
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCCCCCH
QTVSLDAYISRMTEGQDKIYYITADSFNAAKNSPHLEVLREKGIEVLLLSDRIDEWLLSH
HHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCHHHHHHHCCCEEEEECHHHHHHHHHH
LPEYDGKTFTSVTQGDLDLGKLDSEEKKKEQEKQETEFASFVERVKAVLGDKVKDVRLTH
CCCCCCCEECEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
RLTSTPSCIVADNDDMSTQMAKLMAQMGQPVPESKPVFELNPEHVMIVKLADMADEDLFA
HHCCCCCEEEECCCCHHHHHHHHHHHHCCCCCCCCCEEEECCCEEEEEEECCCCCHHHHH
QWSELLLEQAILSEKGSLDDPSEFVGRINKLLLA
HHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MEHQQNHTFSADTGKLLKLMIHSLYSNKEIFLRELVSNAADAADKLRFKALSDGSLFEND
CCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHEECCCCCCEECC
GDLRVRLSFDADLKTITISDNGIGMSRDEVIEHLGTIAKSGTSDFFEQLSGDQVKDSQLI
CCEEEEEEECCCEEEEEEECCCCCCCHHHHHHHHHHHHCCCHHHHHHHHCCCCCHHHHHH
GQFGVGFYSSFIVADKVTVNTRKAGEPASQGTCWISTGESDYTVADIEKAGRGTEITLHL
HHHHHHHHHHHHHCCEEEECCCCCCCCCCCCEEEEECCCCCCEEHHHHHCCCCCEEEEEE
RDDETEFLNDYKLRGIVSKYSDHISIPVEMFKEATEESEGSDGEKVPATEATWEAVNKAT
CCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHH
ALWSCSKSELKDEEYKEFYKHIANDFEDPLTWSHNKVEGEQAYTSLLYIPKRAPYDLWNR
HHHCCCHHHCCHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHEEECCCCCCCCCCC
EKAHGLKLYVQRVFVMDDAEQFMPTYLRFVKGVLDSNDLPLNVSREILQDTRVTAKLRSG
CHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCC
CTKRVLDLLTKLAKKDDDAYNLFWKEFGQVLKEGPAEDSSNKEKIGKLFRFSSTETDSTE
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCCCCCH
QTVSLDAYISRMTEGQDKIYYITADSFNAAKNSPHLEVLREKGIEVLLLSDRIDEWLLSH
HHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCHHHHHHHCCCEEEEECHHHHHHHHHH
LPEYDGKTFTSVTQGDLDLGKLDSEEKKKEQEKQETEFASFVERVKAVLGDKVKDVRLTH
CCCCCCCEECEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
RLTSTPSCIVADNDDMSTQMAKLMAQMGQPVPESKPVFELNPEHVMIVKLADMADEDLFA
HHCCCCCEEEECCCCHHHHHHHHHHHHCCCCCCCCCEEEECCCEEEEEEECCCCCHHHHH
QWSELLLEQAILSEKGSLDDPSEFVGRINKLLLA
HHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA