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The map label for this gene is uspA [H]

Identifier: 119944714

GI number: 119944714

Start: 1199244

End: 1199672

Strand: Direct

Name: uspA [H]

Synonym: Ping_0954

Alternate gene names: 119944714

Gene position: 1199244-1199672 (Clockwise)

Preceding gene: 119944708

Following gene: 119944715

Centisome position: 26.3

GC content: 35.66

Gene sequence:

>429_bases
ATGAGCTATAAACATATATTAGTTGCAGTTGATTTATCTAAATCAAGTGAGAAAGTGATCAGTAGGGCTGTCTTGTTGGC
TAAAGATACAAACGCTAAAGTTTCACTTATTTTTGTCGACGTAGATAACGTATCTAACATTGGACTTGTGAATTTAGAAA
TTGATAGCCTGCCTTCTATTGAGGAAAGAGAGAAAACATTACAACAAGACCTGCAGGCCTTAGCTGTTAAAGCTGATTAT
CCTATTGAAAATGCCATTATAGTAATGGGAAATTTTAACCGCAGGGTAAACGCAGCCGTTGAAAAAATAGGTGCTGACCT
ATTGGTTTGTGGGCATCACCATGATTTTTGGAGTCGATTACTATCAGCCACACGTAAAATACTTAATTCGACAACTACCG
ATCTATTAATTATTTATCTTGATAGCTAA

Upstream 100 bases:

>100_bases
TGGAGTCTTTTTTTCGATGCTAAAGTATATTTTCTTGATATTTAAGCCGTTAGATTAAAGGATTATTTTATTTATTAATA
GAGTTAATTGTGAGGATGAC

Downstream 100 bases:

>100_bases
GCAATCGAGTTTGTTATTAATACTAAAAAACTAAATATAAATAACTGTTCTTTCTTGCTCCGCTGGAATTCAGACCGTTT
TAGGTAGGAACATGAGTGAT

Product: universal stress protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 142; Mature: 141

Protein sequence:

>142_residues
MSYKHILVAVDLSKSSEKVISRAVLLAKDTNAKVSLIFVDVDNVSNIGLVNLEIDSLPSIEEREKTLQQDLQALAVKADY
PIENAIIVMGNFNRRVNAAVEKIGADLLVCGHHHDFWSRLLSATRKILNSTTTDLLIIYLDS

Sequences:

>Translated_142_residues
MSYKHILVAVDLSKSSEKVISRAVLLAKDTNAKVSLIFVDVDNVSNIGLVNLEIDSLPSIEEREKTLQQDLQALAVKADY
PIENAIIVMGNFNRRVNAAVEKIGADLLVCGHHHDFWSRLLSATRKILNSTTTDLLIIYLDS
>Mature_141_residues
SYKHILVAVDLSKSSEKVISRAVLLAKDTNAKVSLIFVDVDNVSNIGLVNLEIDSLPSIEEREKTLQQDLQALAVKADYP
IENAIIVMGNFNRRVNAAVEKIGADLLVCGHHHDFWSRLLSATRKILNSTTTDLLIIYLDS

Specific function: Required for resistance to DNA-damaging agents [H]

COG id: COG0589

COG function: function code T; Universal stress protein UspA and related nucleotide-binding proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the universal stress protein A family [H]

Homologues:

Organism=Escherichia coli, GI1789909, Length=144, Percent_Identity=42.3611111111111, Blast_Score=107, Evalue=3e-25,
Organism=Escherichia coli, GI1788205, Length=141, Percent_Identity=29.7872340425532, Blast_Score=69, Evalue=1e-13,
Organism=Escherichia coli, GI1790358, Length=144, Percent_Identity=31.25, Blast_Score=67, Evalue=4e-13,

Paralogues:

None

Copy number: 1660 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1580 Molecules/Cell In: Early Stationary Phase, Rich Media (Based on E. coli). 290 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 4003 Molecules/Cell In: Growth Phase, G

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014729
- InterPro:   IPR006016 [H]

Pfam domain/function: PF00582 Usp [H]

EC number: NA

Molecular weight: Translated: 15744; Mature: 15613

Theoretical pI: Translated: 6.10; Mature: 6.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSYKHILVAVDLSKSSEKVISRAVLLAKDTNAKVSLIFVDVDNVSNIGLVNLEIDSLPSI
CCCCEEEEEEECCCCHHHHHHHHHEEEECCCCEEEEEEEEECCCCCCEEEEEEECCCCCH
EEREKTLQQDLQALAVKADYPIENAIIVMGNFNRRVNAAVEKIGADLLVCGHHHDFWSRL
HHHHHHHHHHHHHHEEECCCCCCCEEEEEECCCCHHHHHHHHCCCCEEEECCCHHHHHHH
LSATRKILNSTTTDLLIIYLDS
HHHHHHHHCCCCCEEEEEEECC
>Mature Secondary Structure 
SYKHILVAVDLSKSSEKVISRAVLLAKDTNAKVSLIFVDVDNVSNIGLVNLEIDSLPSI
CCCEEEEEEECCCCHHHHHHHHHEEEECCCCEEEEEEEEECCCCCCEEEEEEECCCCCH
EEREKTLQQDLQALAVKADYPIENAIIVMGNFNRRVNAAVEKIGADLLVCGHHHDFWSRL
HHHHHHHHHHHHHHEEECCCCCCCEEEEEECCCCHHHHHHHHCCCCEEEECCCHHHHHHH
LSATRKILNSTTTDLLIIYLDS
HHHHHHHHCCCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 14528314 [H]