Click here to switch to the map view.

The map label for this gene is plsC [H]

Identifier: 119944624

GI number: 119944624

Start: 1079756

End: 1080451

Strand: Reverse

Name: plsC [H]

Synonym: Ping_0863

Alternate gene names: 119944624

Gene position: 1080451-1079756 (Counterclockwise)

Preceding gene: 119944625

Following gene: 119944623

Centisome position: 23.7

GC content: 40.95

Gene sequence:

>696_bases
ATGACCGTCTATTCATTATTTTATTGCTTATTCAGCCCCCGCAATCCCAAGAACACTTATCATTTTGCCATATTATTTAG
CAAATTATCTTGGTTGTTCGGGTTAAAAGTGACCCTACGTATTCCTGAAAGTGCCAAAAATAACGGCTCGGTCGTCTACC
TTGCAAATCACCAGAACAGCTATGATATGGTAACGGTGTCCGGTGCTGTTCAGCCTGGTTCAGTGACTATTGGTAAACAA
AGTTTGGTGTGGATTCCCTTTTTTGGCATTATCTACTGGCTAACGGGTAACATATTAATTAGCCGAGATAATAAAAATAA
ATCACGTAATACTATTAACGAAGTAGTGGATCAGATGCGCGCTAAAAACTTGGCTGTTTGGATATTCCCGGAAGGTACCC
GCAGCCGTGGTCGTGGTTTATTACCTTTTAAAATGGGGGCATTTCATACGGCATTACAAGCCGGTGTCAATGTTGTCCCC
ACGGTGACGTCAAATACGCATAAGCAGGTCAATCTAAACCGTTGGAATAATGGTGAAGTGATTGTTGAAATGTTAGAGCC
CATTGATATTACCCAGTATAAAAAACGTGAAATCAGGCGCTTAATGGAAGACTCTCACGCTATTATGTTAGAAAAATACC
AGCAATTAAATCAAGAAGTAAACCGCCCTGATACCAATTCAGACCGCCGCGATTAA

Upstream 100 bases:

>100_bases
AAAATCGAAATTATTGAAGCTGCGCAAATACATTCAAGAGACTCTTAATATTATGTTATTTATTATCCGCGTTATAATGC
TTTTTGTGATAGTTATATTG

Downstream 100 bases:

>100_bases
GAGGAATTAATAATGGAAAAAGCATTAAGTTTAGAAGAGTTACTGGCAGAATATCGTGAAGAAACAGAAGAAATTGTAGA
AGCCATTTTAGAAGATGGCA

Product: 1-acyl-sn-glycerol-3-phosphate acyltransferases

Products: NA

Alternate protein names: 1-AGP acyltransferase; 1-AGPAT; Lysophosphatidic acid acyltransferase; LPAAT; Phosphatidic acid synthase; PA synthase [H]

Number of amino acids: Translated: 231; Mature: 230

Protein sequence:

>231_residues
MTVYSLFYCLFSPRNPKNTYHFAILFSKLSWLFGLKVTLRIPESAKNNGSVVYLANHQNSYDMVTVSGAVQPGSVTIGKQ
SLVWIPFFGIIYWLTGNILISRDNKNKSRNTINEVVDQMRAKNLAVWIFPEGTRSRGRGLLPFKMGAFHTALQAGVNVVP
TVTSNTHKQVNLNRWNNGEVIVEMLEPIDITQYKKREIRRLMEDSHAIMLEKYQQLNQEVNRPDTNSDRRD

Sequences:

>Translated_231_residues
MTVYSLFYCLFSPRNPKNTYHFAILFSKLSWLFGLKVTLRIPESAKNNGSVVYLANHQNSYDMVTVSGAVQPGSVTIGKQ
SLVWIPFFGIIYWLTGNILISRDNKNKSRNTINEVVDQMRAKNLAVWIFPEGTRSRGRGLLPFKMGAFHTALQAGVNVVP
TVTSNTHKQVNLNRWNNGEVIVEMLEPIDITQYKKREIRRLMEDSHAIMLEKYQQLNQEVNRPDTNSDRRD
>Mature_230_residues
TVYSLFYCLFSPRNPKNTYHFAILFSKLSWLFGLKVTLRIPESAKNNGSVVYLANHQNSYDMVTVSGAVQPGSVTIGKQS
LVWIPFFGIIYWLTGNILISRDNKNKSRNTINEVVDQMRAKNLAVWIFPEGTRSRGRGLLPFKMGAFHTALQAGVNVVPT
VTSNTHKQVNLNRWNNGEVIVEMLEPIDITQYKKREIRRLMEDSHAIMLEKYQQLNQEVNRPDTNSDRRD

Specific function: Converts lysophosphatidic acid (LPA) into phosphatidic acid by incorporating an acyl moiety at the 2 position. This enzyme can utilize either acyl-CoA or acyl-ACP as the fatty acyl donor [H]

COG id: COG0204

COG function: function code I; 1-acyl-sn-glycerol-3-phosphate acyltransferase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI5453718, Length=221, Percent_Identity=27.6018099547511, Blast_Score=110, Evalue=9e-25,
Organism=Homo sapiens, GI15100175, Length=221, Percent_Identity=27.6018099547511, Blast_Score=110, Evalue=9e-25,
Organism=Homo sapiens, GI6041665, Length=190, Percent_Identity=30, Blast_Score=104, Evalue=5e-23,
Organism=Escherichia coli, GI1789395, Length=220, Percent_Identity=55, Blast_Score=271, Evalue=2e-74,
Organism=Caenorhabditis elegans, GI17564032, Length=214, Percent_Identity=28.5046728971963, Blast_Score=114, Evalue=4e-26,
Organism=Caenorhabditis elegans, GI17568319, Length=211, Percent_Identity=29.8578199052133, Blast_Score=108, Evalue=3e-24,
Organism=Saccharomyces cerevisiae, GI6320151, Length=193, Percent_Identity=31.0880829015544, Blast_Score=107, Evalue=2e-24,
Organism=Drosophila melanogaster, GI281364648, Length=221, Percent_Identity=28.9592760180996, Blast_Score=118, Evalue=3e-27,
Organism=Drosophila melanogaster, GI24582856, Length=221, Percent_Identity=28.9592760180996, Blast_Score=118, Evalue=3e-27,
Organism=Drosophila melanogaster, GI24582854, Length=221, Percent_Identity=28.9592760180996, Blast_Score=118, Evalue=3e-27,
Organism=Drosophila melanogaster, GI24641614, Length=214, Percent_Identity=29.9065420560748, Blast_Score=107, Evalue=5e-24,
Organism=Drosophila melanogaster, GI24641612, Length=214, Percent_Identity=29.9065420560748, Blast_Score=107, Evalue=5e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002123
- InterPro:   IPR004552 [H]

Pfam domain/function: PF01553 Acyltransferase [H]

EC number: =2.3.1.51 [H]

Molecular weight: Translated: 26508; Mature: 26377

Theoretical pI: Translated: 10.29; Mature: 10.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVYSLFYCLFSPRNPKNTYHFAILFSKLSWLFGLKVTLRIPESAKNNGSVVYLANHQNS
CHHHHEEHHHCCCCCCCCCEEEEHHHHHHHHHHCEEEEEECCCCCCCCCCEEEEECCCCC
YDMVTVSGAVQPGSVTIGKQSLVWIPFFGIIYWLTGNILISRDNKNKSRNTINEVVDQMR
CEEEEEECCCCCCEEEECCCEEEEHHHHHHHHHHHCCEEEEECCCCCHHHHHHHHHHHHH
AKNLAVWIFPEGTRSRGRGLLPFKMGAFHTALQAGVNVVPTVTSNTHKQVNLNRWNNGEV
HCCEEEEEEECCCCCCCCCCCCCHHHHHHHHHHCCCEEEEEECCCCCCEEEEEECCCCCE
IVEMLEPIDITQYKKREIRRLMEDSHAIMLEKYQQLNQEVNRPDTNSDRRD
EEEECCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
TVYSLFYCLFSPRNPKNTYHFAILFSKLSWLFGLKVTLRIPESAKNNGSVVYLANHQNS
HHHHEEHHHCCCCCCCCCEEEEHHHHHHHHHHCEEEEEECCCCCCCCCCEEEEECCCCC
YDMVTVSGAVQPGSVTIGKQSLVWIPFFGIIYWLTGNILISRDNKNKSRNTINEVVDQMR
CEEEEEECCCCCCEEEECCCEEEEHHHHHHHHHHHCCEEEEECCCCCHHHHHHHHHHHHH
AKNLAVWIFPEGTRSRGRGLLPFKMGAFHTALQAGVNVVPTVTSNTHKQVNLNRWNNGEV
HCCEEEEEEECCCCCCCCCCCCCHHHHHHHHHHCCCEEEEEECCCCCCEEEEEECCCCCE
IVEMLEPIDITQYKKREIRRLMEDSHAIMLEKYQQLNQEVNRPDTNSDRRD
EEEECCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1557036; 9278503 [H]