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The map label for this gene is nudD [H]

Identifier: 119944532

GI number: 119944532

Start: 963631

End: 964101

Strand: Direct

Name: nudD [H]

Synonym: Ping_0765

Alternate gene names: 119944532

Gene position: 963631-964101 (Clockwise)

Preceding gene: 119944531

Following gene: 119944533

Centisome position: 21.13

GC content: 33.55

Gene sequence:

>471_bases
ATGCTCCCATTAGTAACATTTAAGACTGTGATTAAATCGACGCCACTTGTATCTATTGACCTTATTGTACGCAATAACAA
CGGCCAAATTTTGCTTGGTAAACGCACCAACCGTCCTGCAAAAAGAGATTGGTTTGTTCCTGGTGGGCGAATATTAAAAG
ATGAATCCTTTGAGCGTGCATTTAAACGCTTAATAAAAGCAGAATTAGATTTAACAGAAGTAGTGTCAAAATTTAAAGGG
GTTTATCAGCATTTTTATAAAGATAATTTTTCAGAAGATAAATTTACAACGCACTATGTTGTTTTAGCTTATGAAATTAC
CTTTAATGGTAAGTTATCATTGCTGCCGGTTGAACAGCACTCCTGTTATAAGTGGTTTTCTGAAACTGATTTATTGGTAG
ATGAAAAGGTTCACGCTCACAGCAAATGGTATTTTCAAAAAGATAAACAAGCAGATTTACTATTTAAATAA

Upstream 100 bases:

>100_bases
TTTGGTAAGTTTTATTCGCCTTTAAAATTACAATAAATGTCTCAGTTTAAAACGTTACGTGTTGAAATTATTGAATAAAG
TTTAATGGAAAATCAACATT

Downstream 100 bases:

>100_bases
TTAATGAGTTCTTAATGCTTTGAGCTTCATTATTGACTCGGAACTTGAAACTGAAACTGGAAAATAATTTATGATCTCTC
CTGTTATTCTGGCCGGTGGT

Product: GDP-mannose mannosyl hydrolase

Products: GDP; mannose [C]

Alternate protein names: GDPMH; Colanic acid biosynthesis protein wcaH [H]

Number of amino acids: Translated: 156; Mature: 156

Protein sequence:

>156_residues
MLPLVTFKTVIKSTPLVSIDLIVRNNNGQILLGKRTNRPAKRDWFVPGGRILKDESFERAFKRLIKAELDLTEVVSKFKG
VYQHFYKDNFSEDKFTTHYVVLAYEITFNGKLSLLPVEQHSCYKWFSETDLLVDEKVHAHSKWYFQKDKQADLLFK

Sequences:

>Translated_156_residues
MLPLVTFKTVIKSTPLVSIDLIVRNNNGQILLGKRTNRPAKRDWFVPGGRILKDESFERAFKRLIKAELDLTEVVSKFKG
VYQHFYKDNFSEDKFTTHYVVLAYEITFNGKLSLLPVEQHSCYKWFSETDLLVDEKVHAHSKWYFQKDKQADLLFK
>Mature_156_residues
MLPLVTFKTVIKSTPLVSIDLIVRNNNGQILLGKRTNRPAKRDWFVPGGRILKDESFERAFKRLIKAELDLTEVVSKFKG
VYQHFYKDNFSEDKFTTHYVVLAYEITFNGKLSLLPVEQHSCYKWFSETDLLVDEKVHAHSKWYFQKDKQADLLFK

Specific function: It could participate in the regulation of cell wall biosynthesis by influencing the concentration of GDP-mannose or GDP-glucose in the cell. May be involved in the degradation of GDP-mannose and GDP-glucose, diverting the GDP to the synthesis of GDP-fucos

COG id: COG0494

COG function: function code LR; NTP pyrophosphohydrolases including oxidative damage repair enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 nudix hydrolase domain [H]

Homologues:

Organism=Escherichia coli, GI87082031, Length=146, Percent_Identity=54.1095890410959, Blast_Score=162, Evalue=8e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR021161
- InterPro:   IPR020084
- InterPro:   IPR000086
- InterPro:   IPR015797 [H]

Pfam domain/function: PF00293 NUDIX [H]

EC number: NA

Molecular weight: Translated: 18346; Mature: 18346

Theoretical pI: Translated: 9.86; Mature: 9.86

Prosite motif: PS00893 NUDIX

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLPLVTFKTVIKSTPLVSIDLIVRNNNGQILLGKRTNRPAKRDWFVPGGRILKDESFERA
CCCCHHHHHHHCCCCCEEEEEEEECCCCEEEEECCCCCCCCCCEECCCCEEECCCHHHHH
FKRLIKAELDLTEVVSKFKGVYQHFYKDNFSEDKFTTHYVVLAYEITFNGKLSLLPVEQH
HHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEEEEEEEECCEEEEEECCCC
SCYKWFSETDLLVDEKVHAHSKWYFQKDKQADLLFK
HHHHHCCCCCCEECCCCCCCCCEEECCCCCCCCCCC
>Mature Secondary Structure
MLPLVTFKTVIKSTPLVSIDLIVRNNNGQILLGKRTNRPAKRDWFVPGGRILKDESFERA
CCCCHHHHHHHCCCCCEEEEEEEECCCCEEEEECCCCCCCCCCEECCCCEEECCCHHHHH
FKRLIKAELDLTEVVSKFKGVYQHFYKDNFSEDKFTTHYVVLAYEITFNGKLSLLPVEQH
HHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEEEEEEEECCEEEEEECCCC
SCYKWFSETDLLVDEKVHAHSKWYFQKDKQADLLFK
HHHHHCCCCCCEECCCCCCCCCEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: GDP-mannose; H2O [C]

Specific reaction: GDP-mannose + H2O = GDP + mannose [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]