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The map label for this gene is aspS

Identifier: 119944470

GI number: 119944470

Start: 889337

End: 891115

Strand: Direct

Name: aspS

Synonym: Ping_0699

Alternate gene names: 119944470

Gene position: 889337-891115 (Clockwise)

Preceding gene: 119944465

Following gene: 119944472

Centisome position: 19.5

GC content: 44.01

Gene sequence:

>1779_bases
ATGCGCACTATGTATTGTGGCGAAGTGACTGAAGCCGTCTTAGGTCAGGAAATTCAGTTAGTAGGTTGGATCAATAAACA
GCGCGATTTAGGCGGTGTAATCTTTTTAGATATGCGCGACCGTGCCGGTATTGTACAAGTGTTTTTTGATGCAGATACAC
CCATAGCAACGGCACTTGCGACTACGGTACGTAATGAATTCTGTATCCAAATTAAAGGCTTAGTTCGCGCGCGTCCCGAA
GGTCAAGTCAACAAAGATATGACCACCGGTGGGATTGAGATTCTAGGCCTTGAACTCGAAATATTAAACCGCTCAGAGCC
ATTACCGCTTGATAGCAACCAGCAGAACAGTGAAGAGCAGCGTTTACGTTACCGTTATCTGGATTTACGTCGCCCGGAAA
TGGCCAAACGGATGCAGTTCCGCGCTAAAGTAAGCAGTTTTGTGCGTCGTTTCCTCGATGATCAGGATTTTTTAGACGTT
GAAACGCCTATTTTGACCAAAGCGACACCGGAAGGCGCGCGTGATTATTTAGTGCCAAGCCGAACCCATAAAGGGAAATT
CTTTGCCTTGCCGCAATCTCCACAGCTGTTTAAACAATTATTAATGATGTCCGGTATGGATCGTTATTACCAAATTGTTA
AATGTTTCCGAGATGAAGATTTACGTGCCGACCGCCAGCCTGAATTTACCCAAATAGATATTGAAACCTCCTTTATGAAT
GCGGATCAGGTGATGGAGATCAGCGAAGAGATGATAGTGAAGCTTTTCAAAGAGATGCTCAATGTTGATTTAGGCAACTT
TCCTAAAATGACTTATGCCGAAGCACTGCGCCGTTTTGGCAGTGATAAACCTGATCTGCGTATTGATTTTGAACTGTATG
ATGTTGCTGATTTAATGAAAGACGTTGAATTTAACGTTTTCTCCGGTCCTGCAAATGATCCGGACAGCCGTGTTGCCGTT
ATCTGTGTACCGGGTGGCGCAAAACTTTCGCGTAAAAATATTGATGAATATGGAAAATTTGTGACTATCTACGGTGCTAA
AGGACTTGCATGGATGAAAGTCAATGAAGTGGCTAAAGGTTTAGAAGGTGTACAATCACCGGTTGCTAAATTCTTAAATG
AAGAAATTGTCACAGAGTTACTCATCCGTACGGGTGCAAAAGATGGTGATATCATCTTATTTGGCGCTGACAAATCAAAT
ATTGTCAGCGAAGCTATCGGCGCATTACGTCTTAAAGTCGCGCAAGACTTAGGGTTGGTTAAAGATCAATGGAAACCGCT
TTGGGTTATCGATTTCCCGATGTTTGAACCGCTGGATGATGGCGGATTAACACCGCTGCACCATCCTTTTACCGCGCCCA
TTGGTTTAACAGTTGAAGAATTGGAAGCAAATCCTGTTGGCGCTATCTCCAATGCCTACGATATGGTCTTAAACGGTTGT
GAACTCGGTGGTGGTAGTGTGCGTATCCATAAACAAGATATGCAGGCGGCTATTTTCCGCATTCTAAAGATCAGCGATGA
AGAAGCTGAAGATAAATTTGGTTTCTTATTAGAAGCCCTTAAATACGGTGCTCCACCGCATGCAGGTTTAGCCTTTGGTT
TAGACCGTTTAGTGATGTTAATGACCGGCACAAGCTCAATTCGTGACGTCATTGCTTTCCCGAAAACGGCTTCTGCTGCC
TGTCCTTTAACCAATGCACCAAGTTTTGCTAACCCGGCGGTGCTGGCTGAGTTAAACGTTGCTGTTGTTGCCGATCCGAA
GAAAGTTATTAGTGAATAA

Upstream 100 bases:

>100_bases
AAGCAGATGGTCATTTTTTTATTTAGCTGTGTTGCTATTAACTGTTTTCTTCTATAATGCACGCATTATTTTTATATGAT
ATTTAAAACAGGAATCGATA

Downstream 100 bases:

>100_bases
GCTTAGGGGTTTAAGGCTTGGGGCTTTAGGGCTTTGGGGCTTGAGGGTTTCGAGCTGTCAGCTGTCAGCCGTCAGCTTTG
AGCTTTGAGCTTTCGGGCGT

Product: aspartyl-tRNA synthetase

Products: NA

Alternate protein names: Aspartate--tRNA ligase; AspRS

Number of amino acids: Translated: 592; Mature: 592

Protein sequence:

>592_residues
MRTMYCGEVTEAVLGQEIQLVGWINKQRDLGGVIFLDMRDRAGIVQVFFDADTPIATALATTVRNEFCIQIKGLVRARPE
GQVNKDMTTGGIEILGLELEILNRSEPLPLDSNQQNSEEQRLRYRYLDLRRPEMAKRMQFRAKVSSFVRRFLDDQDFLDV
ETPILTKATPEGARDYLVPSRTHKGKFFALPQSPQLFKQLLMMSGMDRYYQIVKCFRDEDLRADRQPEFTQIDIETSFMN
ADQVMEISEEMIVKLFKEMLNVDLGNFPKMTYAEALRRFGSDKPDLRIDFELYDVADLMKDVEFNVFSGPANDPDSRVAV
ICVPGGAKLSRKNIDEYGKFVTIYGAKGLAWMKVNEVAKGLEGVQSPVAKFLNEEIVTELLIRTGAKDGDIILFGADKSN
IVSEAIGALRLKVAQDLGLVKDQWKPLWVIDFPMFEPLDDGGLTPLHHPFTAPIGLTVEELEANPVGAISNAYDMVLNGC
ELGGGSVRIHKQDMQAAIFRILKISDEEAEDKFGFLLEALKYGAPPHAGLAFGLDRLVMLMTGTSSIRDVIAFPKTASAA
CPLTNAPSFANPAVLAELNVAVVADPKKVISE

Sequences:

>Translated_592_residues
MRTMYCGEVTEAVLGQEIQLVGWINKQRDLGGVIFLDMRDRAGIVQVFFDADTPIATALATTVRNEFCIQIKGLVRARPE
GQVNKDMTTGGIEILGLELEILNRSEPLPLDSNQQNSEEQRLRYRYLDLRRPEMAKRMQFRAKVSSFVRRFLDDQDFLDV
ETPILTKATPEGARDYLVPSRTHKGKFFALPQSPQLFKQLLMMSGMDRYYQIVKCFRDEDLRADRQPEFTQIDIETSFMN
ADQVMEISEEMIVKLFKEMLNVDLGNFPKMTYAEALRRFGSDKPDLRIDFELYDVADLMKDVEFNVFSGPANDPDSRVAV
ICVPGGAKLSRKNIDEYGKFVTIYGAKGLAWMKVNEVAKGLEGVQSPVAKFLNEEIVTELLIRTGAKDGDIILFGADKSN
IVSEAIGALRLKVAQDLGLVKDQWKPLWVIDFPMFEPLDDGGLTPLHHPFTAPIGLTVEELEANPVGAISNAYDMVLNGC
ELGGGSVRIHKQDMQAAIFRILKISDEEAEDKFGFLLEALKYGAPPHAGLAFGLDRLVMLMTGTSSIRDVIAFPKTASAA
CPLTNAPSFANPAVLAELNVAVVADPKKVISE
>Mature_592_residues
MRTMYCGEVTEAVLGQEIQLVGWINKQRDLGGVIFLDMRDRAGIVQVFFDADTPIATALATTVRNEFCIQIKGLVRARPE
GQVNKDMTTGGIEILGLELEILNRSEPLPLDSNQQNSEEQRLRYRYLDLRRPEMAKRMQFRAKVSSFVRRFLDDQDFLDV
ETPILTKATPEGARDYLVPSRTHKGKFFALPQSPQLFKQLLMMSGMDRYYQIVKCFRDEDLRADRQPEFTQIDIETSFMN
ADQVMEISEEMIVKLFKEMLNVDLGNFPKMTYAEALRRFGSDKPDLRIDFELYDVADLMKDVEFNVFSGPANDPDSRVAV
ICVPGGAKLSRKNIDEYGKFVTIYGAKGLAWMKVNEVAKGLEGVQSPVAKFLNEEIVTELLIRTGAKDGDIILFGADKSN
IVSEAIGALRLKVAQDLGLVKDQWKPLWVIDFPMFEPLDDGGLTPLHHPFTAPIGLTVEELEANPVGAISNAYDMVLNGC
ELGGGSVRIHKQDMQAAIFRILKISDEEAEDKFGFLLEALKYGAPPHAGLAFGLDRLVMLMTGTSSIRDVIAFPKTASAA
CPLTNAPSFANPAVLAELNVAVVADPKKVISE

Specific function: Unknown

COG id: COG0173

COG function: function code J; Aspartyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family

Homologues:

Organism=Homo sapiens, GI40789249, Length=596, Percent_Identity=39.9328859060403, Blast_Score=403, Evalue=1e-112,
Organism=Homo sapiens, GI5031815, Length=263, Percent_Identity=28.5171102661597, Blast_Score=86, Evalue=1e-16,
Organism=Homo sapiens, GI194272210, Length=263, Percent_Identity=28.5171102661597, Blast_Score=85, Evalue=2e-16,
Organism=Homo sapiens, GI45439306, Length=293, Percent_Identity=23.5494880546075, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI4758762, Length=290, Percent_Identity=22.4137931034483, Blast_Score=69, Evalue=1e-11,
Organism=Escherichia coli, GI1788173, Length=584, Percent_Identity=68.4931506849315, Blast_Score=845, Evalue=0.0,
Organism=Escherichia coli, GI1789256, Length=284, Percent_Identity=26.7605633802817, Blast_Score=88, Evalue=2e-18,
Organism=Escherichia coli, GI1790571, Length=298, Percent_Identity=27.1812080536913, Blast_Score=87, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI32566633, Length=603, Percent_Identity=32.5041459369818, Blast_Score=325, Evalue=4e-89,
Organism=Caenorhabditis elegans, GI71994340, Length=259, Percent_Identity=25.8687258687259, Blast_Score=89, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI17535925, Length=259, Percent_Identity=25.8687258687259, Blast_Score=88, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17535927, Length=259, Percent_Identity=25.8687258687259, Blast_Score=88, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17551876, Length=276, Percent_Identity=24.6376811594203, Blast_Score=72, Evalue=7e-13,
Organism=Saccharomyces cerevisiae, GI6325153, Length=632, Percent_Identity=34.0189873417722, Blast_Score=281, Evalue=3e-76,
Organism=Saccharomyces cerevisiae, GI6321807, Length=254, Percent_Identity=27.9527559055118, Blast_Score=81, Evalue=6e-16,
Organism=Saccharomyces cerevisiae, GI6320242, Length=156, Percent_Identity=32.0512820512821, Blast_Score=76, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6323011, Length=267, Percent_Identity=26.5917602996255, Blast_Score=73, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6324256, Length=112, Percent_Identity=30.3571428571429, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24584738, Length=591, Percent_Identity=36.2098138747885, Blast_Score=331, Evalue=9e-91,
Organism=Drosophila melanogaster, GI24640849, Length=290, Percent_Identity=27.5862068965517, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24640851, Length=290, Percent_Identity=27.5862068965517, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI17136276, Length=255, Percent_Identity=25.8823529411765, Blast_Score=73, Evalue=4e-13,

Paralogues:

None

Copy number: 1320 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): SYD_PSYIN (A1SST6)

Other databases:

- EMBL:   CP000510
- RefSeq:   YP_942150.1
- ProteinModelPortal:   A1SST6
- SMR:   A1SST6
- STRING:   A1SST6
- GeneID:   4627030
- GenomeReviews:   CP000510_GR
- KEGG:   pin:Ping_0699
- eggNOG:   COG0173
- HOGENOM:   HBG396032
- OMA:   AFPKTQQ
- PhylomeDB:   A1SST6
- BioCyc:   PING357804:PING_0699-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00044_B
- InterPro:   IPR004364
- InterPro:   IPR018150
- InterPro:   IPR006195
- InterPro:   IPR020564
- InterPro:   IPR004524
- InterPro:   IPR018153
- InterPro:   IPR002312
- InterPro:   IPR004115
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR004365
- Gene3D:   G3DSA:3.30.1360.30
- Gene3D:   G3DSA:2.40.50.140
- PANTHER:   PTHR22594
- PANTHER:   PTHR22594:SF5
- PRINTS:   PR01042
- TIGRFAMs:   TIGR00459

Pfam domain/function: PF02938 GAD; PF00152 tRNA-synt_2; PF01336 tRNA_anti; SSF50249 Nucleic_acid_OB

EC number: =6.1.1.12

Molecular weight: Translated: 65993; Mature: 65993

Theoretical pI: Translated: 4.75; Mature: 4.75

Prosite motif: PS50862 AA_TRNA_LIGASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRTMYCGEVTEAVLGQEIQLVGWINKQRDLGGVIFLDMRDRAGIVQVFFDADTPIATALA
CCCEECHHHHHHHCCCCEEEEEECCCCCCCCCEEEEEECCCCCEEEEEECCCCCHHHHHH
TTVRNEFCIQIKGLVRARPEGQVNKDMTTGGIEILGLELEILNRSEPLPLDSNQQNSEEQ
HHHCCCCEEEEEHHHHCCCCCCCCCCCCCCCEEEEEEEEEEECCCCCCCCCCCCCCCHHH
RLRYRYLDLRRPEMAKRMQFRAKVSSFVRRFLDDQDFLDVETPILTKATPEGARDYLVPS
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEECCCCEEECCCCCCCCCCCCCC
RTHKGKFFALPQSPQLFKQLLMMSGMDRYYQIVKCFRDEDLRADRQPEFTQIDIETSFMN
CCCCCEEEECCCCHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCEEEEEEEHHCC
ADQVMEISEEMIVKLFKEMLNVDLGNFPKMTYAEALRRFGSDKPDLRIDFELYDVADLMK
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCCEEEEEEHHHHHHHHH
DVEFNVFSGPANDPDSRVAVICVPGGAKLSRKNIDEYGKFVTIYGAKGLAWMKVNEVAKG
HCCCEEECCCCCCCCCCEEEEEECCCCCCCCCCHHHHCCEEEEECCCCEEEEEHHHHHHH
LEGVQSPVAKFLNEEIVTELLIRTGAKDGDIILFGADKSNIVSEAIGALRLKVAQDLGLV
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHCCCH
KDQWKPLWVIDFPMFEPLDDGGLTPLHHPFTAPIGLTVEELEANPVGAISNAYDMVLNGC
HHCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCHHHHHHHHHCCC
ELGGGSVRIHKQDMQAAIFRILKISDEEAEDKFGFLLEALKYGAPPHAGLAFGLDRLVML
CCCCCEEEEEHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
MTGTSSIRDVIAFPKTASAACPLTNAPSFANPAVLAELNVAVVADPKKVISE
HCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEEEEEEEEECCHHHHCC
>Mature Secondary Structure
MRTMYCGEVTEAVLGQEIQLVGWINKQRDLGGVIFLDMRDRAGIVQVFFDADTPIATALA
CCCEECHHHHHHHCCCCEEEEEECCCCCCCCCEEEEEECCCCCEEEEEECCCCCHHHHHH
TTVRNEFCIQIKGLVRARPEGQVNKDMTTGGIEILGLELEILNRSEPLPLDSNQQNSEEQ
HHHCCCCEEEEEHHHHCCCCCCCCCCCCCCCEEEEEEEEEEECCCCCCCCCCCCCCCHHH
RLRYRYLDLRRPEMAKRMQFRAKVSSFVRRFLDDQDFLDVETPILTKATPEGARDYLVPS
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEECCCCEEECCCCCCCCCCCCCC
RTHKGKFFALPQSPQLFKQLLMMSGMDRYYQIVKCFRDEDLRADRQPEFTQIDIETSFMN
CCCCCEEEECCCCHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCEEEEEEEHHCC
ADQVMEISEEMIVKLFKEMLNVDLGNFPKMTYAEALRRFGSDKPDLRIDFELYDVADLMK
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCCEEEEEEHHHHHHHHH
DVEFNVFSGPANDPDSRVAVICVPGGAKLSRKNIDEYGKFVTIYGAKGLAWMKVNEVAKG
HCCCEEECCCCCCCCCCEEEEEECCCCCCCCCCHHHHCCEEEEECCCCEEEEEHHHHHHH
LEGVQSPVAKFLNEEIVTELLIRTGAKDGDIILFGADKSNIVSEAIGALRLKVAQDLGLV
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHCCCH
KDQWKPLWVIDFPMFEPLDDGGLTPLHHPFTAPIGLTVEELEANPVGAISNAYDMVLNGC
HHCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCHHHHHHHHHCCC
ELGGGSVRIHKQDMQAAIFRILKISDEEAEDKFGFLLEALKYGAPPHAGLAFGLDRLVML
CCCCCEEEEEHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
MTGTSSIRDVIAFPKTASAACPLTNAPSFANPAVLAELNVAVVADPKKVISE
HCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEEEEEEEEECCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA