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The map label for this gene is rbsK [H]

Identifier: 119944129

GI number: 119944129

Start: 445648

End: 446574

Strand: Direct

Name: rbsK [H]

Synonym: Ping_0344

Alternate gene names: 119944129

Gene position: 445648-446574 (Clockwise)

Preceding gene: 119944128

Following gene: 119944130

Centisome position: 9.77

GC content: 48.33

Gene sequence:

>927_bases
ATGAATAAATTAGTCGTTCTGGGCAGCGTTAACGCCGATCATGTTTTACAAGTTCCCTCTTTTCCGCGTCCCGGAGAAAC
TCTGCACGGCACAGGCTATGCTGTTATTCCCGGGGGAAAGGGCGCCAACCAGGCTGTCGCAGCTGCGCGTTTGGGCGCCG
ATGTGGCATTTATTGCCTGCTTGGGTGATGATAGTTTCGGGATTAATATTCGTGACGCTTTTAAAAGCGATGGAATCAAT
GTTGATGGGGTGATGATTGAAAAAAACACCCCAACAGGGATCGCAATGATTCAAGTATCGGCCACCGGAGAGAACAGTAT
TTGCATCTCAGCCGAAGCCAATAATCACCTCACACCTGAACGTATAAAACCTTTTTCCTCTCTTATTAGCGCAGCTGAAA
TATTACTGATGCAATTGGAAACGCCTATTGAAACGATCCAGGCCGCTGCTGAAACGGCAAAACTCGCCGGGACAGTGGTT
GTCTTAAATCCGGCACCTGCGCAATCATTAAGCGATGAGTTGTTAAAACTTGTTGATATTATCACCCCCAATGAAACCGA
AGCTGAGCAGCTTACGGGTGTTCAAGTCAAGGATATGCCCTCGGCACAACAAGCCGCTGAAAAGTTACATGACAAGGGTA
TCGAAATGGTAATGATAACCCTAGGCAGTGAGGGGGTATGGCTGAGCCAGGCTGGTAAGGGTAAGCAGATAAAAGGCTTT
ACCGTGAAAGCTGTGGATACAACAGCCGCAGGAGATACTTTCAACGGTGCGCTATTGACCCGCTTGCTGGAAAAGGCAAG
CGTGGAAGAATCGATTCGTTTTGCCCATGCGGCTGCCGCGATCACGGTCACCGGTAAAGGGGCACAAACATCGATTCCAG
ATCGCCAGAGTGTAGAGAAATTTTTACAGCAGATGGACAATAAATGA

Upstream 100 bases:

>100_bases
ACTCTTAAAATCTAAAATAAATTGTTTAAGCTTGTTTAAAACAGCCTTAAACAATGTATTTTAAACAATGTGTTTTAACT
TTAATTAAAATGGTTTATTT

Downstream 100 bases:

>100_bases
TTATTTAAGGATTTGAACAAGCAAATGGCAACCATAAAAGATGTAGCAAAACATGCGGGCGTGTCTACTTCAACGGTCAG
CCATGTTTTAAATCAAACAC

Product: ribokinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 308; Mature: 308

Protein sequence:

>308_residues
MNKLVVLGSVNADHVLQVPSFPRPGETLHGTGYAVIPGGKGANQAVAAARLGADVAFIACLGDDSFGINIRDAFKSDGIN
VDGVMIEKNTPTGIAMIQVSATGENSICISAEANNHLTPERIKPFSSLISAAEILLMQLETPIETIQAAAETAKLAGTVV
VLNPAPAQSLSDELLKLVDIITPNETEAEQLTGVQVKDMPSAQQAAEKLHDKGIEMVMITLGSEGVWLSQAGKGKQIKGF
TVKAVDTTAAGDTFNGALLTRLLEKASVEESIRFAHAAAAITVTGKGAQTSIPDRQSVEKFLQQMDNK

Sequences:

>Translated_308_residues
MNKLVVLGSVNADHVLQVPSFPRPGETLHGTGYAVIPGGKGANQAVAAARLGADVAFIACLGDDSFGINIRDAFKSDGIN
VDGVMIEKNTPTGIAMIQVSATGENSICISAEANNHLTPERIKPFSSLISAAEILLMQLETPIETIQAAAETAKLAGTVV
VLNPAPAQSLSDELLKLVDIITPNETEAEQLTGVQVKDMPSAQQAAEKLHDKGIEMVMITLGSEGVWLSQAGKGKQIKGF
TVKAVDTTAAGDTFNGALLTRLLEKASVEESIRFAHAAAAITVTGKGAQTSIPDRQSVEKFLQQMDNK
>Mature_308_residues
MNKLVVLGSVNADHVLQVPSFPRPGETLHGTGYAVIPGGKGANQAVAAARLGADVAFIACLGDDSFGINIRDAFKSDGIN
VDGVMIEKNTPTGIAMIQVSATGENSICISAEANNHLTPERIKPFSSLISAAEILLMQLETPIETIQAAAETAKLAGTVV
VLNPAPAQSLSDELLKLVDIITPNETEAEQLTGVQVKDMPSAQQAAEKLHDKGIEMVMITLGSEGVWLSQAGKGKQIKGF
TVKAVDTTAAGDTFNGALLTRLLEKASVEESIRFAHAAAAITVTGKGAQTSIPDRQSVEKFLQQMDNK

Specific function: Ribose metabolism; first step. [C]

COG id: COG0524

COG function: function code G; Sugar kinases, ribokinase family

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Homo sapiens, GI11545855, Length=297, Percent_Identity=39.0572390572391, Blast_Score=167, Evalue=1e-41,
Organism=Homo sapiens, GI32484973, Length=263, Percent_Identity=26.2357414448669, Blast_Score=66, Evalue=4e-11,
Organism=Homo sapiens, GI32484975, Length=263, Percent_Identity=26.2357414448669, Blast_Score=66, Evalue=4e-11,
Organism=Escherichia coli, GI1790193, Length=301, Percent_Identity=57.1428571428571, Blast_Score=311, Evalue=5e-86,
Organism=Escherichia coli, GI87082343, Length=309, Percent_Identity=31.3915857605178, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI87081971, Length=305, Percent_Identity=26.5573770491803, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI1788491, Length=262, Percent_Identity=23.2824427480916, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1788484, Length=290, Percent_Identity=25.5172413793103, Blast_Score=70, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17532905, Length=308, Percent_Identity=39.9350649350649, Blast_Score=179, Evalue=2e-45,
Organism=Saccharomyces cerevisiae, GI6319884, Length=335, Percent_Identity=28.6567164179104, Blast_Score=112, Evalue=6e-26,
Organism=Drosophila melanogaster, GI20128807, Length=301, Percent_Identity=37.2093023255814, Blast_Score=151, Evalue=5e-37,
Organism=Drosophila melanogaster, GI24583886, Length=307, Percent_Identity=33.2247557003257, Blast_Score=134, Evalue=6e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011611
- InterPro:   IPR002173
- InterPro:   IPR011877
- InterPro:   IPR002139 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: =2.7.1.15 [H]

Molecular weight: Translated: 32268; Mature: 32268

Theoretical pI: Translated: 4.80; Mature: 4.80

Prosite motif: PS00584 PFKB_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKLVVLGSVNADHVLQVPSFPRPGETLHGTGYAVIPGGKGANQAVAAARLGADVAFIAC
CCCEEEEECCCCCCEEECCCCCCCCCCCCCCCEEEECCCCCCCHHHHHHHHCCCEEEEEE
LGDDSFGINIRDAFKSDGINVDGVMIEKNTPTGIAMIQVSATGENSICISAEANNHLTPE
ECCCCCCCEEHHHHCCCCCCCCEEEEECCCCCCEEEEEEEECCCCCEEEEECCCCCCCHH
RIKPFSSLISAAEILLMQLETPIETIQAAAETAKLAGTVVVLNPAPAQSLSDELLKLVDI
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCEEEEEECCCCCHHHHHHHHHHHHH
ITPNETEAEQLTGVQVKDMPSAQQAAEKLHDKGIEMVMITLGSEGVWLSQAGKGKQIKGF
CCCCCCCHHHHCCCEEECCCCHHHHHHHHHHCCCEEEEEEECCCCEEEECCCCCCEECCE
TVKAVDTTAAGDTFNGALLTRLLEKASVEESIRFAHAAAAITVTGKGAQTSIPDRQSVEK
EEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHEEEEEEEEECCCCCCCCCCHHHHHH
FLQQMDNK
HHHHHCCC
>Mature Secondary Structure
MNKLVVLGSVNADHVLQVPSFPRPGETLHGTGYAVIPGGKGANQAVAAARLGADVAFIAC
CCCEEEEECCCCCCEEECCCCCCCCCCCCCCCEEEECCCCCCCHHHHHHHHCCCEEEEEE
LGDDSFGINIRDAFKSDGINVDGVMIEKNTPTGIAMIQVSATGENSICISAEANNHLTPE
ECCCCCCCEEHHHHCCCCCCCCEEEEECCCCCCEEEEEEEECCCCCEEEEECCCCCCCHH
RIKPFSSLISAAEILLMQLETPIETIQAAAETAKLAGTVVVLNPAPAQSLSDELLKLVDI
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCEEEEEECCCCCHHHHHHHHHHHHH
ITPNETEAEQLTGVQVKDMPSAQQAAEKLHDKGIEMVMITLGSEGVWLSQAGKGKQIKGF
CCCCCCCHHHHCCCEEECCCCHHHHHHHHHHCCCEEEEEEECCCCEEEECCCCCCEECCE
TVKAVDTTAAGDTFNGALLTRLLEKASVEESIRFAHAAAAITVTGKGAQTSIPDRQSVEK
EEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHEEEEEEEEECCCCCCCCCCHHHHHH
FLQQMDNK
HHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]