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The map label for this gene is tkt1 [H]

Identifier: 119944124

GI number: 119944124

Start: 439294

End: 441297

Strand: Direct

Name: tkt1 [H]

Synonym: Ping_0339

Alternate gene names: 119944124

Gene position: 439294-441297 (Clockwise)

Preceding gene: 119944123

Following gene: 119944125

Centisome position: 9.63

GC content: 45.46

Gene sequence:

>2004_bases
ATGCCACCTCGTAAAGAGCTAGCTAACGCGATTCGTGCACTCAGTATGGATGCCGTACAAAAAGCCAATTCAGGTCACCC
TGGAGCTCCAATGGGGATGGCTGATATAGCCGAAGTCCTTTGGCGTGATTTCTTAAAACATAACCCAACTAACCCGCAGT
GGGCCGATCGTGACCGTTTTGTTCTGTCTAATGGCCATGGATCAATGCTGATTTACTCGCTGCTGCATTTAACCGGTTAT
GCATTGTCAATTGAGGATCTTAAATCGTTCCGTCAACTGCATTCTAAAACACCTGGACATCCTGAATACGGTTACGCACC
GGGTATCGAAACAACAACAGGTCCGTTAGGTCAAGGTCTGACTAATGCGGTGGGTATGGCGATTGCTGAAAAATCATTAG
CAGCACAATTTAACCGTCCAGCGCACGATATCGTTGATCATTTTACTTATACTTTCTTAGGTGATGGTTGTTTAATGGAA
GGGATCTCACATGAAGCTTCCTCATTAGCGGGTACTTTAGGACTCGGAAAACTGATTGCATTCTGGGATGACAACGGAAT
TTCAATCGATGGTAACGTTGATGGTTGGTTTACGGATGATACACCGGCACGTTTTAAAGCATACGGCTGGCAGGTAATTT
CTGTTGATGGCCATAACAGCGAAGAGATTAAAGCGGCGATTATCGCAGCTCAAGCTGAAACATCTAAACCAACGATGATT
TGTTGTAAAACCATTATCGGTTTTGGTGCGCCAACCAAACAGGGTACACATGGCTGTCACGGTGCGCCACTTGGTGCCGA
TGAAATAATCGCAACACGTAAAGCATTAGGCTGGAACTACGGTGATTTTGAAATTCCTGCAGATATCTATGCCGGTTGGG
ATAATAAAGAACAGGGGCAAGCCCTTGAAAATTCATGGGATGAACAGTTTGCCGCATATGCAAGCGCGTACCCTGAATTA
GCCGCTGAATATAAGCGTCGTATCAATGGCGACATGCCAAGCGACTGGGAAGTTAAATCAACGCAGTATATCGAGGAATT
ACAAGCGAGTCAGGCGAATATTGCAACCCGTAAAGCGTCACAAAACTGCATCGAAGCATTTGGCACAATGTTGCCTGAAT
TATTAGGTGGCTCTGCCGATTTAGCCCCTTCGAACCTGACTATGTGGTCTGGTACTAAAGCGATTACTGCTGATGACGCG
TCGGGCAACTATTTACACTACGGTGTACGTGAGTTTGCAATGTCAGCCATTGTTAACGGTATTGCTTTGCATAAAGGTTT
TGTGCCCTTTGGCGCAACCTTCTTAATGTTTATGGAATATGCGCGTAATGGTTTACGTATGTCGGCCTTAATGAAGCAGC
GTGCGATTCAAGTATTCACCCATGACTCAATCGGTCTGGGCGAAGATGGGCCCACTCATCAACCCGTTGAACAAATTGCC
AGCTTGCGTTTAACTCCAAATATGAACACCTGGCGCCCTTGTGACAGCGTAGAGTCTGCCGTTGCCTGGAAATCAGCCAT
TGAGCGAATCGATGGTCCAACATCACTGGTCTTCAGTCGTCAAAATCTGCAACCTCAAGCGCGTGATGCACAGCAGCTCA
GCGATGTCGCTAAAGGTGGTTATGTCTTACTTGAAAGTAAAGAGTTTGACAGTGCAAATTCAGCGTCGATTATGCTGATT
GCAACGGGTTCTGAAGTACAACTTGCTGTTGAAGCCTACAACGAATTAACAGCACAGGGTAAAGCGGTACGTGTTGTGTC
TCTTCCTTGTACAGATATTTTTGAAACTCAAAGTGCCGAGTATAAAGAGTCTGTTCTACCTGCCCTTGTGACTAAACGTC
TGGCAATAGAGGCCGGTATTGCTGATTACTGGTACAAATATGTTGGCCTAAATGGAAAAGTTATTGGTATGACCACCTTT
GGTGAGTCAGCACCCGCTGAACAGTTATTTAAAATGTTTGGTTTCACCGTAGAAAACGTTGTTGAGTCCGCTCAGACTTT
ATAA

Upstream 100 bases:

>100_bases
TTGCCAGTACCCCACAATATTTGGGATAATCGCGGCGCTCTACACCACATCACTAAATTTTCAGCAATTGAACTCAATTG
CAACCTATCAGGAGAAAGAC

Downstream 100 bases:

>100_bases
TATTAGTTAATCAACCCTGTTTATTAGGGGAATAAAAGCCGCGTTTATCGCGGCTTTTTTGTTTTAAGCGTTGATTAGAT
TAATAATAGATTCCTTTCCA

Product: transketolase

Products: NA

Alternate protein names: TK 1 [H]

Number of amino acids: Translated: 667; Mature: 666

Protein sequence:

>667_residues
MPPRKELANAIRALSMDAVQKANSGHPGAPMGMADIAEVLWRDFLKHNPTNPQWADRDRFVLSNGHGSMLIYSLLHLTGY
ALSIEDLKSFRQLHSKTPGHPEYGYAPGIETTTGPLGQGLTNAVGMAIAEKSLAAQFNRPAHDIVDHFTYTFLGDGCLME
GISHEASSLAGTLGLGKLIAFWDDNGISIDGNVDGWFTDDTPARFKAYGWQVISVDGHNSEEIKAAIIAAQAETSKPTMI
CCKTIIGFGAPTKQGTHGCHGAPLGADEIIATRKALGWNYGDFEIPADIYAGWDNKEQGQALENSWDEQFAAYASAYPEL
AAEYKRRINGDMPSDWEVKSTQYIEELQASQANIATRKASQNCIEAFGTMLPELLGGSADLAPSNLTMWSGTKAITADDA
SGNYLHYGVREFAMSAIVNGIALHKGFVPFGATFLMFMEYARNGLRMSALMKQRAIQVFTHDSIGLGEDGPTHQPVEQIA
SLRLTPNMNTWRPCDSVESAVAWKSAIERIDGPTSLVFSRQNLQPQARDAQQLSDVAKGGYVLLESKEFDSANSASIMLI
ATGSEVQLAVEAYNELTAQGKAVRVVSLPCTDIFETQSAEYKESVLPALVTKRLAIEAGIADYWYKYVGLNGKVIGMTTF
GESAPAEQLFKMFGFTVENVVESAQTL

Sequences:

>Translated_667_residues
MPPRKELANAIRALSMDAVQKANSGHPGAPMGMADIAEVLWRDFLKHNPTNPQWADRDRFVLSNGHGSMLIYSLLHLTGY
ALSIEDLKSFRQLHSKTPGHPEYGYAPGIETTTGPLGQGLTNAVGMAIAEKSLAAQFNRPAHDIVDHFTYTFLGDGCLME
GISHEASSLAGTLGLGKLIAFWDDNGISIDGNVDGWFTDDTPARFKAYGWQVISVDGHNSEEIKAAIIAAQAETSKPTMI
CCKTIIGFGAPTKQGTHGCHGAPLGADEIIATRKALGWNYGDFEIPADIYAGWDNKEQGQALENSWDEQFAAYASAYPEL
AAEYKRRINGDMPSDWEVKSTQYIEELQASQANIATRKASQNCIEAFGTMLPELLGGSADLAPSNLTMWSGTKAITADDA
SGNYLHYGVREFAMSAIVNGIALHKGFVPFGATFLMFMEYARNGLRMSALMKQRAIQVFTHDSIGLGEDGPTHQPVEQIA
SLRLTPNMNTWRPCDSVESAVAWKSAIERIDGPTSLVFSRQNLQPQARDAQQLSDVAKGGYVLLESKEFDSANSASIMLI
ATGSEVQLAVEAYNELTAQGKAVRVVSLPCTDIFETQSAEYKESVLPALVTKRLAIEAGIADYWYKYVGLNGKVIGMTTF
GESAPAEQLFKMFGFTVENVVESAQTL
>Mature_666_residues
PPRKELANAIRALSMDAVQKANSGHPGAPMGMADIAEVLWRDFLKHNPTNPQWADRDRFVLSNGHGSMLIYSLLHLTGYA
LSIEDLKSFRQLHSKTPGHPEYGYAPGIETTTGPLGQGLTNAVGMAIAEKSLAAQFNRPAHDIVDHFTYTFLGDGCLMEG
ISHEASSLAGTLGLGKLIAFWDDNGISIDGNVDGWFTDDTPARFKAYGWQVISVDGHNSEEIKAAIIAAQAETSKPTMIC
CKTIIGFGAPTKQGTHGCHGAPLGADEIIATRKALGWNYGDFEIPADIYAGWDNKEQGQALENSWDEQFAAYASAYPELA
AEYKRRINGDMPSDWEVKSTQYIEELQASQANIATRKASQNCIEAFGTMLPELLGGSADLAPSNLTMWSGTKAITADDAS
GNYLHYGVREFAMSAIVNGIALHKGFVPFGATFLMFMEYARNGLRMSALMKQRAIQVFTHDSIGLGEDGPTHQPVEQIAS
LRLTPNMNTWRPCDSVESAVAWKSAIERIDGPTSLVFSRQNLQPQARDAQQLSDVAKGGYVLLESKEFDSANSASIMLIA
TGSEVQLAVEAYNELTAQGKAVRVVSLPCTDIFETQSAEYKESVLPALVTKRLAIEAGIADYWYKYVGLNGKVIGMTTFG
ESAPAEQLFKMFGFTVENVVESAQTL

Specific function: Unknown

COG id: COG0021

COG function: function code G; Transketolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transketolase family [H]

Homologues:

Organism=Homo sapiens, GI205277463, Length=687, Percent_Identity=26.4919941775837, Blast_Score=159, Evalue=6e-39,
Organism=Homo sapiens, GI4507521, Length=687, Percent_Identity=26.4919941775837, Blast_Score=159, Evalue=6e-39,
Organism=Homo sapiens, GI133778974, Length=586, Percent_Identity=25.4266211604096, Blast_Score=136, Evalue=5e-32,
Organism=Escherichia coli, GI48994911, Length=668, Percent_Identity=71.5568862275449, Blast_Score=1021, Evalue=0.0,
Organism=Escherichia coli, GI1788808, Length=665, Percent_Identity=66.1654135338346, Blast_Score=952, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17539652, Length=679, Percent_Identity=24.4477172312224, Blast_Score=158, Evalue=7e-39,
Organism=Saccharomyces cerevisiae, GI6325331, Length=672, Percent_Identity=48.0654761904762, Blast_Score=591, Evalue=1e-169,
Organism=Saccharomyces cerevisiae, GI6319593, Length=673, Percent_Identity=44.4279346210996, Blast_Score=545, Evalue=1e-156,
Organism=Drosophila melanogaster, GI45551847, Length=706, Percent_Identity=25.7790368271955, Blast_Score=154, Evalue=2e-37,
Organism=Drosophila melanogaster, GI45550715, Length=706, Percent_Identity=25.7790368271955, Blast_Score=154, Evalue=2e-37,
Organism=Drosophila melanogaster, GI24645119, Length=672, Percent_Identity=25.1488095238095, Blast_Score=129, Evalue=6e-30,
Organism=Drosophila melanogaster, GI24666278, Length=261, Percent_Identity=31.0344827586207, Blast_Score=119, Evalue=5e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009014
- InterPro:   IPR015941
- InterPro:   IPR005475
- InterPro:   IPR005478
- InterPro:   IPR020826
- InterPro:   IPR005476
- InterPro:   IPR005474 [H]

Pfam domain/function: PF02779 Transket_pyr; PF02780 Transketolase_C; PF00456 Transketolase_N [H]

EC number: =2.2.1.1 [H]

Molecular weight: Translated: 72414; Mature: 72283

Theoretical pI: Translated: 4.88; Mature: 4.88

Prosite motif: PS00801 TRANSKETOLASE_1 ; PS00802 TRANSKETOLASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPPRKELANAIRALSMDAVQKANSGHPGAPMGMADIAEVLWRDFLKHNPTNPQWADRDRF
CCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCE
VLSNGHGSMLIYSLLHLTGYALSIEDLKSFRQLHSKTPGHPEYGYAPGIETTTGPLGQGL
EEECCCCHHHHHHHHHHHCCEEEHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHH
TNAVGMAIAEKSLAAQFNRPAHDIVDHFTYTFLGDGCLMEGISHEASSLAGTLGLGKLIA
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCHHHHHHCCHHHHHHHHHHCCCCEEE
FWDDNGISIDGNVDGWFTDDTPARFKAYGWQVISVDGHNSEEIKAAIIAAQAETSKPTMI
EECCCCEEECCCCCCEECCCCCCCEEECCEEEEEECCCCCHHHEEHEEEEECCCCCCHHH
CCKTIIGFGAPTKQGTHGCHGAPLGADEIIATRKALGWNYGDFEIPADIYAGWDNKEQGQ
HHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHCCCCCCCCCC
ALENSWDEQFAAYASAYPELAAEYKRRINGDMPSDWEVKSTQYIEELQASQANIATRKAS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
QNCIEAFGTMLPELLGGSADLAPSNLTMWSGTKAITADDASGNYLHYGVREFAMSAIVNG
HHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCEEEEECCCCCCEEEHHHHHHHHHHHHHH
IALHKGFVPFGATFLMFMEYARNGLRMSALMKQRAIQVFTHDSIGLGEDGPTHQPVEQIA
HHHHCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHEEECCCCCCCCCCCCCHHHHHHH
SLRLTPNMNTWRPCDSVESAVAWKSAIERIDGPTSLVFSRQNLQPQARDAQQLSDVAKGG
HEECCCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHEEEECCCCCCHHHHHHHHHHHHCCC
YVLLESKEFDSANSASIMLIATGSEVQLAVEAYNELTAQGKAVRVVSLPCTDIFETQSAE
EEEEECCCCCCCCCCEEEEEEECCCEEEHHHHHHHHHCCCCEEEEEECCCHHHHHCCCHH
YKESVLPALVTKRLAIEAGIADYWYKYVGLNGKVIGMTTFGESAPAEQLFKMFGFTVENV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHCCHHHHH
VESAQTL
HHHHHCC
>Mature Secondary Structure 
PPRKELANAIRALSMDAVQKANSGHPGAPMGMADIAEVLWRDFLKHNPTNPQWADRDRF
CCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCE
VLSNGHGSMLIYSLLHLTGYALSIEDLKSFRQLHSKTPGHPEYGYAPGIETTTGPLGQGL
EEECCCCHHHHHHHHHHHCCEEEHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHH
TNAVGMAIAEKSLAAQFNRPAHDIVDHFTYTFLGDGCLMEGISHEASSLAGTLGLGKLIA
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCHHHHHHCCHHHHHHHHHHCCCCEEE
FWDDNGISIDGNVDGWFTDDTPARFKAYGWQVISVDGHNSEEIKAAIIAAQAETSKPTMI
EECCCCEEECCCCCCEECCCCCCCEEECCEEEEEECCCCCHHHEEHEEEEECCCCCCHHH
CCKTIIGFGAPTKQGTHGCHGAPLGADEIIATRKALGWNYGDFEIPADIYAGWDNKEQGQ
HHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHCCCCCCCCCC
ALENSWDEQFAAYASAYPELAAEYKRRINGDMPSDWEVKSTQYIEELQASQANIATRKAS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
QNCIEAFGTMLPELLGGSADLAPSNLTMWSGTKAITADDASGNYLHYGVREFAMSAIVNG
HHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCEEEEECCCCCCEEEHHHHHHHHHHHHHH
IALHKGFVPFGATFLMFMEYARNGLRMSALMKQRAIQVFTHDSIGLGEDGPTHQPVEQIA
HHHHCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHEEECCCCCCCCCCCCCHHHHHHH
SLRLTPNMNTWRPCDSVESAVAWKSAIERIDGPTSLVFSRQNLQPQARDAQQLSDVAKGG
HEECCCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHEEEECCCCCCHHHHHHHHHHHHCCC
YVLLESKEFDSANSASIMLIATGSEVQLAVEAYNELTAQGKAVRVVSLPCTDIFETQSAE
EEEEECCCCCCCCCCEEEEEEECCCEEEHHHHHHHHHCCCCEEEEEECCCHHHHHCCCHH
YKESVLPALVTKRLAIEAGIADYWYKYVGLNGKVIGMTTFGESAPAEQLFKMFGFTVENV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHCCHHHHH
VESAQTL
HHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]