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The map label for this gene is gcp

Identifier: 119944099

GI number: 119944099

Start: 414336

End: 415361

Strand: Direct

Name: gcp

Synonym: Ping_0314

Alternate gene names: 119944099

Gene position: 414336-415361 (Clockwise)

Preceding gene: 119944090

Following gene: 119944100

Centisome position: 9.09

GC content: 45.22

Gene sequence:

>1026_bases
ATGCGTATTTTAGGTATTGAAACTTCATGTGATGAAACCGGTATCGCCATTTATGATGATCAACTAGGTTTGTTATCGCA
TCAGTTATATAGTCAAGTTGAATTACATGCTGACTACGGTGGTGTGGTACCTGAGCTTGCCTCTCGAGATCATGTACGTA
AAACTATTCCGTTAATTAAAGAAGCATTAGTGGCTGCAAATTGTACCAAAGAGAGTCTTGATGGTATTGCTTATACTGCT
GGACCAGGGTTAGTAGGAGCGTTATTAGTAGGGTCATGTATTGGGCGCAGTCTGGCCTATGCGTGGAATATACCGGCTAT
TGCAGTACACCATATGGAAGGGCATCTACTGGCCCCTATGCTCGAAGAAAATCGTCCGGAATTTCCGTTTTTGGCGTTGC
TGGTATCGGGCGGCCATACGCTGATGGTTGAGGTTGAAAATATTGGTGAATACCAGGTATTAGGTGAAAGTATTGATGAT
GCTGCTGGAGAGGCCTTTGATAAGACAGCCAAATTACTTGGACTCGATTATCCGGGTGGACCGCGTTTGGCAAAATTAGC
TGAAAAGGGGGAGCCCAAACGCTTTATTTTTCCACGACCAATGACCACTAAACCTGGACTTGATTTTAGTTTTAGTGGAT
TAAAAACCTTTGCGGCTAATACCATTGCCAAGGAAGGTAAAGATCCGCAAACTCAGGCAGATATTGCCTTGGCATTTCAG
GATGCGGTCATCGATACGGTTGCTATCAAATGTAAGCGTGCTTTAAAACAAACAGGATTAAAGCGCTTAGTTGTGGCGGG
TGGCGTCAGCGCCAACCTGTCTTTGCGTAGCCAATTGGCCGTTTTAATGAAATCCCTTGGTGGTGAAGTTTTTTATCCCC
GCAATGAATTTTGTACGGATAACGGTGCAATGATCGCTTATGCGGGTATGCAGCGCTTAAAAGCCGGGCATTTTGAAGGC
TTGGGGATTCAGGCAAAACCAAGATGGCCTCTTGATCAGCTGCTTAGCGTGCGCAGCGAGCTCTGA

Upstream 100 bases:

>100_bases
TTTCTTTATAACCGGATGAAAAAAGCATTCGGGATAGTCTTTTTACGTTAAACTAGCATTTTTTATCTATCGTCACTTTT
ATCAAAGGAACATTTATCAT

Downstream 100 bases:

>100_bases
TGGATTAGTCATTTAAATTTTCATTAATTCAGTATAATATGACGAAACTTTTATTTTTATTTCAAAAAAAAAGAATACAA
CACTATGGTCGAGAAAAATA

Product: O-sialoglycoprotein endopeptidase Gcp

Products: NA

Alternate protein names: Glycoprotease

Number of amino acids: Translated: 341; Mature: 341

Protein sequence:

>341_residues
MRILGIETSCDETGIAIYDDQLGLLSHQLYSQVELHADYGGVVPELASRDHVRKTIPLIKEALVAANCTKESLDGIAYTA
GPGLVGALLVGSCIGRSLAYAWNIPAIAVHHMEGHLLAPMLEENRPEFPFLALLVSGGHTLMVEVENIGEYQVLGESIDD
AAGEAFDKTAKLLGLDYPGGPRLAKLAEKGEPKRFIFPRPMTTKPGLDFSFSGLKTFAANTIAKEGKDPQTQADIALAFQ
DAVIDTVAIKCKRALKQTGLKRLVVAGGVSANLSLRSQLAVLMKSLGGEVFYPRNEFCTDNGAMIAYAGMQRLKAGHFEG
LGIQAKPRWPLDQLLSVRSEL

Sequences:

>Translated_341_residues
MRILGIETSCDETGIAIYDDQLGLLSHQLYSQVELHADYGGVVPELASRDHVRKTIPLIKEALVAANCTKESLDGIAYTA
GPGLVGALLVGSCIGRSLAYAWNIPAIAVHHMEGHLLAPMLEENRPEFPFLALLVSGGHTLMVEVENIGEYQVLGESIDD
AAGEAFDKTAKLLGLDYPGGPRLAKLAEKGEPKRFIFPRPMTTKPGLDFSFSGLKTFAANTIAKEGKDPQTQADIALAFQ
DAVIDTVAIKCKRALKQTGLKRLVVAGGVSANLSLRSQLAVLMKSLGGEVFYPRNEFCTDNGAMIAYAGMQRLKAGHFEG
LGIQAKPRWPLDQLLSVRSEL
>Mature_341_residues
MRILGIETSCDETGIAIYDDQLGLLSHQLYSQVELHADYGGVVPELASRDHVRKTIPLIKEALVAANCTKESLDGIAYTA
GPGLVGALLVGSCIGRSLAYAWNIPAIAVHHMEGHLLAPMLEENRPEFPFLALLVSGGHTLMVEVENIGEYQVLGESIDD
AAGEAFDKTAKLLGLDYPGGPRLAKLAEKGEPKRFIFPRPMTTKPGLDFSFSGLKTFAANTIAKEGKDPQTQADIALAFQ
DAVIDTVAIKCKRALKQTGLKRLVVAGGVSANLSLRSQLAVLMKSLGGEVFYPRNEFCTDNGAMIAYAGMQRLKAGHFEG
LGIQAKPRWPLDQLLSVRSEL

Specific function: Could Be A Metalloprotease. [C]

COG id: COG0533

COG function: function code O; Metal-dependent proteases with possible chaperone activity

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M22 family

Homologues:

Organism=Homo sapiens, GI116812636, Length=355, Percent_Identity=35.4929577464789, Blast_Score=187, Evalue=8e-48,
Organism=Homo sapiens, GI8923380, Length=318, Percent_Identity=29.874213836478, Blast_Score=142, Evalue=5e-34,
Organism=Escherichia coli, GI1789445, Length=334, Percent_Identity=73.9520958083832, Blast_Score=522, Evalue=1e-149,
Organism=Caenorhabditis elegans, GI17557464, Length=327, Percent_Identity=31.4984709480122, Blast_Score=149, Evalue=2e-36,
Organism=Caenorhabditis elegans, GI71995670, Length=342, Percent_Identity=31.8713450292398, Blast_Score=140, Evalue=8e-34,
Organism=Saccharomyces cerevisiae, GI6320099, Length=375, Percent_Identity=34.1333333333333, Blast_Score=180, Evalue=2e-46,
Organism=Saccharomyces cerevisiae, GI6322891, Length=348, Percent_Identity=27.8735632183908, Blast_Score=116, Evalue=5e-27,
Organism=Drosophila melanogaster, GI20129063, Length=340, Percent_Identity=33.8235294117647, Blast_Score=175, Evalue=4e-44,
Organism=Drosophila melanogaster, GI21357207, Length=328, Percent_Identity=30.7926829268293, Blast_Score=143, Evalue=2e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GCP_PSYIN (A1SRR5)

Other databases:

- EMBL:   CP000510
- RefSeq:   YP_941779.1
- ProteinModelPortal:   A1SRR5
- SMR:   A1SRR5
- STRING:   A1SRR5
- MEROPS:   M22.001
- GeneID:   4624892
- GenomeReviews:   CP000510_GR
- KEGG:   pin:Ping_0314
- eggNOG:   COG0533
- HOGENOM:   HBG304663
- OMA:   PAVGVHH
- PhylomeDB:   A1SRR5
- BioCyc:   PING357804:PING_0314-MONOMER
- GO:   GO:0006508
- HAMAP:   MF_01445
- InterPro:   IPR022450
- InterPro:   IPR000905
- InterPro:   IPR017860
- InterPro:   IPR017861
- PANTHER:   PTHR11735
- PRINTS:   PR00789
- TIGRFAMs:   TIGR03723
- TIGRFAMs:   TIGR00329

Pfam domain/function: PF00814 Peptidase_M22

EC number: =3.4.24.57

Molecular weight: Translated: 36714; Mature: 36714

Theoretical pI: Translated: 6.32; Mature: 6.32

Prosite motif: PS01016 GLYCOPROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRILGIETSCDETGIAIYDDQLGLLSHQLYSQVELHADYGGVVPELASRDHVRKTIPLIK
CEEEEECCCCCCCCEEEECCCHHHHHHHHHHHHEEECCCCCCCHHHHCHHHHHHHHHHHH
EALVAANCTKESLDGIAYTAGPGLVGALLVGSCIGRSLAYAWNIPAIAVHHMEGHLLAPM
HHHHHHCCCHHHHCCEEEECCCHHHHHHHHHHHHHHHHHHEECCCEEEEEECCCCEECHH
LEENRPEFPFLALLVSGGHTLMVEVENIGEYQVLGESIDDAAGEAFDKTAKLLGLDYPGG
HHCCCCCCCEEEEEECCCCEEEEEECCCCCEEECCCHHHHHHHHHHHHHHHHHCCCCCCC
PRLAKLAEKGEPKRFIFPRPMTTKPGLDFSFSGLKTFAANTIAKEGKDPQTQADIALAFQ
CHHHHHHHCCCCCEEECCCCCCCCCCCCEEHHHHHHHHHHHHHHCCCCCCCHHHHHHHHH
DAVIDTVAIKCKRALKQTGLKRLVVAGGVSANLSLRSQLAVLMKSLGGEVFYPRNEFCTD
HHHHHHHHHHHHHHHHHCCHHEEEEECCCCCCHHHHHHHHHHHHHHCCCEECCCCCCCCC
NGAMIAYAGMQRLKAGHFEGLGIQAKPRWPLDQLLSVRSEL
CCCEEEEHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHCC
>Mature Secondary Structure
MRILGIETSCDETGIAIYDDQLGLLSHQLYSQVELHADYGGVVPELASRDHVRKTIPLIK
CEEEEECCCCCCCCEEEECCCHHHHHHHHHHHHEEECCCCCCCHHHHCHHHHHHHHHHHH
EALVAANCTKESLDGIAYTAGPGLVGALLVGSCIGRSLAYAWNIPAIAVHHMEGHLLAPM
HHHHHHCCCHHHHCCEEEECCCHHHHHHHHHHHHHHHHHHEECCCEEEEEECCCCEECHH
LEENRPEFPFLALLVSGGHTLMVEVENIGEYQVLGESIDDAAGEAFDKTAKLLGLDYPGG
HHCCCCCCCEEEEEECCCCEEEEEECCCCCEEECCCHHHHHHHHHHHHHHHHHCCCCCCC
PRLAKLAEKGEPKRFIFPRPMTTKPGLDFSFSGLKTFAANTIAKEGKDPQTQADIALAFQ
CHHHHHHHCCCCCEEECCCCCCCCCCCCEEHHHHHHHHHHHHHHCCCCCCCHHHHHHHHH
DAVIDTVAIKCKRALKQTGLKRLVVAGGVSANLSLRSQLAVLMKSLGGEVFYPRNEFCTD
HHHHHHHHHHHHHHHHHCCHHEEEEECCCCCCHHHHHHHHHHHHHHCCCEECCCCCCCCC
NGAMIAYAGMQRLKAGHFEGLGIQAKPRWPLDQLLSVRSEL
CCCEEEEHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA