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The map label for this gene is yciR [C]

Identifier: 119899788

GI number: 119899788

Start: 3841404

End: 3843584

Strand: Direct

Name: yciR [C]

Synonym: azo3499

Alternate gene names: 119899788

Gene position: 3841404-3843584 (Clockwise)

Preceding gene: 119899787

Following gene: 119899801

Centisome position: 87.78

GC content: 68.41

Gene sequence:

>2181_bases
ATGGTTATTCCAGCAGACCAGCCGTTCCAGGTGCGCTCCGAGCAGACCTCGCCGGCACCGGAACTCGTCTGCCGCATCCT
CGTCGTGGACGACGATCCTGCGCTGCGGCAATCGCTCCCGCGGGCCCTCGCCCGCAATGGGCGCAAGTTTTCCGAAAGCG
ATACCGTGGCCGGCGCCATCGCGCTGCTCGAACGCGAGCCGTTCGACCTCGTGCTGCTGGACTATCGCCTGCCCGACGGC
ACAGGACTCGCGGTGCTCGACTGGCTCGCGCAGCATCAGCGCGAGGAAGCGGTGATCATGATCAGCGGTGAAGACGCCCT
CGACGCCGCCATCGGCGCGCTGCGCGGCGGCGCCGACGACTACCTGCGCAAGCCCTACCACGTGGCGCAGCTGCAGCGCG
CGGTGGAAAGCGCGCTGCACAAGGCGGCGCTGGAGCGCGCGAACCGCGCGATGAGCCAGCGCCTGCGCACCTCCGAGCGC
CTGCATCGCTACCTGGTCGAAAGCTCGCCCGACCTGATCTTCACGCTCGACGCCGAAGGCCGCTTCAGCTACCTCAATCC
ACGCGTCAAGGCGCTGCTCGGCTACGACCGCAACGTGCTGATGCGGCGCCCGTTCACCACGCTGGTGATGCCGGAGGATG
TCGATCGCATCGCCACGCTGCTGTACGCCCCGGTCGCCGGCCCGGGCGAGAGCTTCCACGTCGAGCTGCGGCTGCGCCGC
AACCGCGAGCTGCTCGCCGGCGACAGCCCGGAGTGGATCACCGTCGCGCTAACCGGCATCCCGATGCCGGCGCGCGAGGA
CGGGCGTCGCGGCGGCGGCCTGTACGGGGTGGCGCGCGACATCTCCGAACGCAAGCGCGCCGAGGAGATCATCTCCTTCC
AGGCCTACCACGACCAGCTCACCCGTCTGCCCAACCGGGTGCTGTTCAAGGACCGCCTCGAACTCGCGATCGCGCAGGCG
CAGCGCCGCACGGGCGCACTCGCGGTGATGTTCATCGATGTCGACCGCTTCAAGCTGGTGAACGACACCTTCGGCCACGC
CGAGGGCGACATGCTGCTGCGCGGCATCGCTGCCCGCCTCGCGGGCACGCTGCGGCGGGGCGACACGCTGGCGCGCCTGG
GCGGGGACGAATTCACCGTGCTGCTGCCCGACATCAACGGCCCGCAGGACGCCGAGGTCATCGCGCGCAAGATCCTCGAC
TCGCTGTCGGCACCGTTCCCGCTCAGCCACGGCGACTTCCGTGCCACGGCCAGCATCGGCATTGCGCTGTTCCCGCGCGA
CGGCGATGGCGCCGAGGATCTGACCCGCCATGCCGACATTGCGATGTACCAGGTCAAGCGCTCCGGCAAGAACGGTTTCC
GCTTCTTCGACATCGCACTCAACTCGCACTACCGCGAGCGCATCGTGCTGGAGAACGATCTGCGCACTGCGCTGGAGCGG
CGCGAGTTCGAGCTGCACTACCAGCCCCAGATCAGCCTGACCCAGCACCGGGTGGTCGGCATGGAAGCGCTGCTGCGCTG
GAACCACCCCAACCTCGGGCTGGTCAGCCCGGCCACCTTCATTCCGGTGGCCGAGGAGATGGGCCTGATCGGCGACATCA
GCCGCTGGGTGCTGGAAGAGGCCTGCGGCCAGCTTGCGCGCTGGCGCGAGGCCGGCCACAACGACTTGCGGATGTCGCTG
AACCTGTCGCCGCACGACTTCGACAGCCAGGACGTGGTGACGATGGTGACCGAATGTGTGGAACGCCACCGCCTGCCACC
GTCGCAGCTGGAACTGGAGATCACCGAGAGCATGATGATGCAGGACGCCGCCGGCGTTGCCGCCAAGGTGCGCGGGCTGC
GCGAGGCGGGGCTGAGCGTGGCGATCGACGATTTCGGCACCGGCTATTCGGCGCTGGCGTATCTGCAGAAGTTTCCCGTC
AGCACGCTGAAGATCGACCGCAGTTTCGTGCGTGAGCTGGAAGGGCCCAATACCAACCCGATCATCTCGGCGATCACCGG
CATCGCGCGCGGTTTCGGCCTGCAGTTGATCGCGGAAGGGGTGGAGCGTTCGGAGCAGGCGGAAACGCTGCGCACCCTGG
GCTGCGACGTGATGCAGGGTTTTCTGTATGCACGCCCGGCGCCCGCGGCCGAGGCGACCGCCTGGCTCTACGACGCACCG
GACGCCTCCGCGCTGCACTGA

Upstream 100 bases:

>100_bases
AACGAGCTTCCAGATCTTTGTTCCGCTGGAACAAAGGCCCTGATTTGTAGCAATATTCATCTCACAAGACCCATAACGCG
ACCCGACCTCCAGGGGGCTC

Downstream 100 bases:

>100_bases
ACCCGCACGGGCGCGGGTCGGGGCCCTGGCGGGTGTGCGTGTGCACGTTTCCGCCTCGAGGCGGTTTATGTTGAGGACGC
CTGAGCGCGGGCGTCCGAGG

Product: putative signaling protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 726; Mature: 726

Protein sequence:

>726_residues
MVIPADQPFQVRSEQTSPAPELVCRILVVDDDPALRQSLPRALARNGRKFSESDTVAGAIALLEREPFDLVLLDYRLPDG
TGLAVLDWLAQHQREEAVIMISGEDALDAAIGALRGGADDYLRKPYHVAQLQRAVESALHKAALERANRAMSQRLRTSER
LHRYLVESSPDLIFTLDAEGRFSYLNPRVKALLGYDRNVLMRRPFTTLVMPEDVDRIATLLYAPVAGPGESFHVELRLRR
NRELLAGDSPEWITVALTGIPMPAREDGRRGGGLYGVARDISERKRAEEIISFQAYHDQLTRLPNRVLFKDRLELAIAQA
QRRTGALAVMFIDVDRFKLVNDTFGHAEGDMLLRGIAARLAGTLRRGDTLARLGGDEFTVLLPDINGPQDAEVIARKILD
SLSAPFPLSHGDFRATASIGIALFPRDGDGAEDLTRHADIAMYQVKRSGKNGFRFFDIALNSHYRERIVLENDLRTALER
REFELHYQPQISLTQHRVVGMEALLRWNHPNLGLVSPATFIPVAEEMGLIGDISRWVLEEACGQLARWREAGHNDLRMSL
NLSPHDFDSQDVVTMVTECVERHRLPPSQLELEITESMMMQDAAGVAAKVRGLREAGLSVAIDDFGTGYSALAYLQKFPV
STLKIDRSFVRELEGPNTNPIISAITGIARGFGLQLIAEGVERSEQAETLRTLGCDVMQGFLYARPAPAAEATAWLYDAP
DASALH

Sequences:

>Translated_726_residues
MVIPADQPFQVRSEQTSPAPELVCRILVVDDDPALRQSLPRALARNGRKFSESDTVAGAIALLEREPFDLVLLDYRLPDG
TGLAVLDWLAQHQREEAVIMISGEDALDAAIGALRGGADDYLRKPYHVAQLQRAVESALHKAALERANRAMSQRLRTSER
LHRYLVESSPDLIFTLDAEGRFSYLNPRVKALLGYDRNVLMRRPFTTLVMPEDVDRIATLLYAPVAGPGESFHVELRLRR
NRELLAGDSPEWITVALTGIPMPAREDGRRGGGLYGVARDISERKRAEEIISFQAYHDQLTRLPNRVLFKDRLELAIAQA
QRRTGALAVMFIDVDRFKLVNDTFGHAEGDMLLRGIAARLAGTLRRGDTLARLGGDEFTVLLPDINGPQDAEVIARKILD
SLSAPFPLSHGDFRATASIGIALFPRDGDGAEDLTRHADIAMYQVKRSGKNGFRFFDIALNSHYRERIVLENDLRTALER
REFELHYQPQISLTQHRVVGMEALLRWNHPNLGLVSPATFIPVAEEMGLIGDISRWVLEEACGQLARWREAGHNDLRMSL
NLSPHDFDSQDVVTMVTECVERHRLPPSQLELEITESMMMQDAAGVAAKVRGLREAGLSVAIDDFGTGYSALAYLQKFPV
STLKIDRSFVRELEGPNTNPIISAITGIARGFGLQLIAEGVERSEQAETLRTLGCDVMQGFLYARPAPAAEATAWLYDAP
DASALH
>Mature_726_residues
MVIPADQPFQVRSEQTSPAPELVCRILVVDDDPALRQSLPRALARNGRKFSESDTVAGAIALLEREPFDLVLLDYRLPDG
TGLAVLDWLAQHQREEAVIMISGEDALDAAIGALRGGADDYLRKPYHVAQLQRAVESALHKAALERANRAMSQRLRTSER
LHRYLVESSPDLIFTLDAEGRFSYLNPRVKALLGYDRNVLMRRPFTTLVMPEDVDRIATLLYAPVAGPGESFHVELRLRR
NRELLAGDSPEWITVALTGIPMPAREDGRRGGGLYGVARDISERKRAEEIISFQAYHDQLTRLPNRVLFKDRLELAIAQA
QRRTGALAVMFIDVDRFKLVNDTFGHAEGDMLLRGIAARLAGTLRRGDTLARLGGDEFTVLLPDINGPQDAEVIARKILD
SLSAPFPLSHGDFRATASIGIALFPRDGDGAEDLTRHADIAMYQVKRSGKNGFRFFDIALNSHYRERIVLENDLRTALER
REFELHYQPQISLTQHRVVGMEALLRWNHPNLGLVSPATFIPVAEEMGLIGDISRWVLEEACGQLARWREAGHNDLRMSL
NLSPHDFDSQDVVTMVTECVERHRLPPSQLELEITESMMMQDAAGVAAKVRGLREAGLSVAIDDFGTGYSALAYLQKFPV
STLKIDRSFVRELEGPNTNPIISAITGIARGFGLQLIAEGVERSEQAETLRTLGCDVMQGFLYARPAPAAEATAWLYDAP
DASALH

Specific function: Unknown

COG id: COG5001

COG function: function code T; Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 MHYT domain [H]

Homologues:

Organism=Escherichia coli, GI1787541, Length=438, Percent_Identity=37.2146118721461, Blast_Score=295, Evalue=8e-81,
Organism=Escherichia coli, GI87081921, Length=434, Percent_Identity=36.6359447004608, Blast_Score=262, Evalue=5e-71,
Organism=Escherichia coli, GI226510982, Length=437, Percent_Identity=33.6384439359268, Blast_Score=225, Evalue=8e-60,
Organism=Escherichia coli, GI1790496, Length=248, Percent_Identity=36.6935483870968, Blast_Score=163, Evalue=3e-41,
Organism=Escherichia coli, GI87081743, Length=242, Percent_Identity=35.5371900826446, Blast_Score=155, Evalue=1e-38,
Organism=Escherichia coli, GI1788381, Length=606, Percent_Identity=26.4026402640264, Blast_Score=149, Evalue=6e-37,
Organism=Escherichia coli, GI1787055, Length=436, Percent_Identity=25.6880733944954, Blast_Score=148, Evalue=2e-36,
Organism=Escherichia coli, GI87081980, Length=262, Percent_Identity=33.969465648855, Blast_Score=143, Evalue=5e-35,
Organism=Escherichia coli, GI1788502, Length=251, Percent_Identity=34.2629482071713, Blast_Score=143, Evalue=5e-35,
Organism=Escherichia coli, GI1786507, Length=281, Percent_Identity=31.3167259786477, Blast_Score=140, Evalue=4e-34,
Organism=Escherichia coli, GI1788849, Length=253, Percent_Identity=33.596837944664, Blast_Score=132, Evalue=5e-32,
Organism=Escherichia coli, GI87081845, Length=273, Percent_Identity=28.9377289377289, Blast_Score=125, Evalue=1e-29,
Organism=Escherichia coli, GI87082096, Length=430, Percent_Identity=24.8837209302326, Blast_Score=111, Evalue=1e-25,
Organism=Escherichia coli, GI87081881, Length=181, Percent_Identity=35.9116022099448, Blast_Score=96, Evalue=7e-21,
Organism=Escherichia coli, GI87081977, Length=168, Percent_Identity=33.3333333333333, Blast_Score=91, Evalue=3e-19,
Organism=Escherichia coli, GI1787262, Length=160, Percent_Identity=35, Blast_Score=91, Evalue=3e-19,
Organism=Escherichia coli, GI87082007, Length=180, Percent_Identity=34.4444444444444, Blast_Score=91, Evalue=3e-19,
Organism=Escherichia coli, GI1788956, Length=157, Percent_Identity=40.1273885350318, Blast_Score=89, Evalue=8e-19,
Organism=Escherichia coli, GI145693134, Length=178, Percent_Identity=33.1460674157303, Blast_Score=87, Evalue=4e-18,
Organism=Escherichia coli, GI1787816, Length=170, Percent_Identity=31.7647058823529, Blast_Score=83, Evalue=8e-17,
Organism=Escherichia coli, GI1789650, Length=432, Percent_Identity=23.1481481481481, Blast_Score=79, Evalue=1e-15,
Organism=Escherichia coli, GI1786584, Length=181, Percent_Identity=28.1767955801105, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1787802, Length=166, Percent_Identity=30.7228915662651, Blast_Score=77, Evalue=4e-15,
Organism=Escherichia coli, GI1787410, Length=154, Percent_Identity=31.1688311688312, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI1788550, Length=146, Percent_Identity=30.8219178082192, Blast_Score=73, Evalue=5e-14,
Organism=Escherichia coli, GI87081974, Length=167, Percent_Identity=29.940119760479, Blast_Score=70, Evalue=5e-13,
Organism=Escherichia coli, GI1790299, Length=114, Percent_Identity=35.9649122807018, Blast_Score=65, Evalue=2e-11,
Organism=Escherichia coli, GI1786911, Length=120, Percent_Identity=35.8333333333333, Blast_Score=64, Evalue=3e-11,
Organism=Escherichia coli, GI1788085, Length=163, Percent_Identity=29.4478527607362, Blast_Score=63, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR005330 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF03707 MHYT [H]

EC number: NA

Molecular weight: Translated: 80697; Mature: 80697

Theoretical pI: Translated: 5.67; Mature: 5.67

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50110 RESPONSE_REGULATORY ; PS50883 EAL ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVIPADQPFQVRSEQTSPAPELVCRILVVDDDPALRQSLPRALARNGRKFSESDTVAGAI
CCCCCCCCCCCCCCCCCCCHHHEEEEEEECCCHHHHHHHHHHHHHCCCCCCCCCHHHHHH
ALLEREPFDLVLLDYRLPDGTGLAVLDWLAQHQREEAVIMISGEDALDAAIGALRGGADD
HHHCCCCCCEEEEEEECCCCCCHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHCCCCHH
YLRKPYHVAQLQRAVESALHKAALERANRAMSQRLRTSERLHRYLVESSPDLIFTLDAEG
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCC
RFSYLNPRVKALLGYDRNVLMRRPFTTLVMPEDVDRIATLLYAPVAGPGESFHVELRLRR
CEECCCHHHHHHHCCCCCEEEECCCEEEECCCHHHHHHHHHHCCCCCCCCCEEEEEEEEC
NRELLAGDSPEWITVALTGIPMPAREDGRRGGGLYGVARDISERKRAEEIISFQAYHDQL
CCCEECCCCCCEEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
TRLPNRVLFKDRLELAIAQAQRRTGALAVMFIDVDRFKLVNDTFGHAEGDMLLRGIAARL
HHCCHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCHHEECCCCCCCCCHHHHHHHHHHHH
AGTLRRGDTLARLGGDEFTVLLPDINGPQDAEVIARKILDSLSAPFPLSHGDFRATASIG
HHHHHCCCHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEE
IALFPRDGDGAEDLTRHADIAMYQVKRSGKNGFRFFDIALNSHYRERIVLENDLRTALER
EEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCHHHEEEHHHHHHHHHH
REFELHYQPQISLTQHRVVGMEALLRWNHPNLGLVSPATFIPVAEEMGLIGDISRWVLEE
HHEEEEECCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHCCCHHHCCCHHHHHHHHHHH
ACGQLARWREAGHNDLRMSLNLSPHDFDSQDVVTMVTECVERHRLPPSQLELEITESMMM
HHHHHHHHHHCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
QDAAGVAAKVRGLREAGLSVAIDDFGTGYSALAYLQKFPVSTLKIDRSFVRELEGPNTNP
HHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCH
IISAITGIARGFGLQLIAEGVERSEQAETLRTLGCDVMQGFLYARPAPAAEATAWLYDAP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECC
DASALH
CCCCCC
>Mature Secondary Structure
MVIPADQPFQVRSEQTSPAPELVCRILVVDDDPALRQSLPRALARNGRKFSESDTVAGAI
CCCCCCCCCCCCCCCCCCCHHHEEEEEEECCCHHHHHHHHHHHHHCCCCCCCCCHHHHHH
ALLEREPFDLVLLDYRLPDGTGLAVLDWLAQHQREEAVIMISGEDALDAAIGALRGGADD
HHHCCCCCCEEEEEEECCCCCCHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHCCCCHH
YLRKPYHVAQLQRAVESALHKAALERANRAMSQRLRTSERLHRYLVESSPDLIFTLDAEG
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCC
RFSYLNPRVKALLGYDRNVLMRRPFTTLVMPEDVDRIATLLYAPVAGPGESFHVELRLRR
CEECCCHHHHHHHCCCCCEEEECCCEEEECCCHHHHHHHHHHCCCCCCCCCEEEEEEEEC
NRELLAGDSPEWITVALTGIPMPAREDGRRGGGLYGVARDISERKRAEEIISFQAYHDQL
CCCEECCCCCCEEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
TRLPNRVLFKDRLELAIAQAQRRTGALAVMFIDVDRFKLVNDTFGHAEGDMLLRGIAARL
HHCCHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCHHEECCCCCCCCCHHHHHHHHHHHH
AGTLRRGDTLARLGGDEFTVLLPDINGPQDAEVIARKILDSLSAPFPLSHGDFRATASIG
HHHHHCCCHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEE
IALFPRDGDGAEDLTRHADIAMYQVKRSGKNGFRFFDIALNSHYRERIVLENDLRTALER
EEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCHHHEEEHHHHHHHHHH
REFELHYQPQISLTQHRVVGMEALLRWNHPNLGLVSPATFIPVAEEMGLIGDISRWVLEE
HHEEEEECCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHCCCHHHCCCHHHHHHHHHHH
ACGQLARWREAGHNDLRMSLNLSPHDFDSQDVVTMVTECVERHRLPPSQLELEITESMMM
HHHHHHHHHHCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
QDAAGVAAKVRGLREAGLSVAIDDFGTGYSALAYLQKFPVSTLKIDRSFVRELEGPNTNP
HHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCH
IISAITGIARGFGLQLIAEGVERSEQAETLRTLGCDVMQGFLYARPAPAAEATAWLYDAP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECC
DASALH
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]