| Definition | Mycobacterium sp. KMS plasmid pMKMS01, complete sequence. |
|---|---|
| Accession | NC_008703 |
| Length | 302,089 |
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The map label for this gene is fabG [H]
Identifier: 119855019
GI number: 119855019
Start: 139538
End: 140365
Strand: Direct
Name: fabG [H]
Synonym: Mkms_5627
Alternate gene names: 119855019
Gene position: 139538-140365 (Clockwise)
Preceding gene: 119855018
Following gene: 119855020
Centisome position: 46.19
GC content: 67.27
Gene sequence:
>828_bases ATGCGCGAAGTGCGCCCGTTCACCAATCGGCGCCGCGTGAGTGCCGTGAAGGCGGGGGACCGCCGGGTCGCAATTGTCAC TGCCGCCGCCGCGGGAATCGGTAAGGCGATCGCCCTGCGGTGGTGCCGCGAAGGTGGGTGCTGTGTCATGGCCGACACCG ACGGCGAGGGCCTCGATGCGGCCGTGCATGAATTGGCCGAGTCCGGCGCGGCGGTTTGCGGCGTCGCCGGCGACGTTTGC CTCAGCGATGTTGCCAACAGTGTCGTCGAACGGGCGCTGACCGAGTTCGGGCGGCTCGACACACTGTTCAACGTCGTCGG CGGGAGCCTGGCTCGCAACGTGGAGGAGATCAGCGAGGAGCAGTGGCGCAGCCAGATCGACATGAACCTCGGCAGTGTCT TTCAGATGTCCAAACCCGTCATCCCACTCCTGCGCCAGGGTGGCGGCGGGTCGATCGTCAACGTCGCGTCGACGGCCGGG ATCCTCGCCGAGAACAGGTGCTCCGCCTACAGCGCAAGCAAAGGCGGGGTCGTGCTGCTCACGAAGAACATGGCCCTCGA CTTCGCCCGCGACAACATCCGCGTGAACGCGATCGCCCCCGGGGGCACCCGCACGCCGAGGATCGAACGGTTCCTGGCCG AGCACCCCGAACACGCCTCGATGATGGTGGACCTCTGCGCGATGCAGCGTTTCGCAGGACCAGACGAGATCGCGGCGCCG GCTGTGTTTCTTGCCTCGCCCGAGGCGTCCTACATCACCGGTGCCGTACTGCCGGTCGACGGAGGCATGACCGCCGGCGT CACTTTCCGGGCGTTCGAGGCGGTATGA
Upstream 100 bases:
>100_bases GCCGAGCAGAATCAGCGGCGGTTTTGGGGGAGATGGCTGGAATACATGGGTCAGCCTCCCGCATTCGGCGGGCGTGCTTG ATGAAGCTTCTGCCCAGGCT
Downstream 100 bases:
>100_bases GCATGATCCCCAACCGCTGGAATCTACACCGGACCCACGAAAGCACCGCGAGCTGAGATGGAAGCGATCGTTCTCAACGG CACCAACGACGTCGGTCTGA
Product: short-chain dehydrogenase/reductase SDR
Products: NA
Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]
Number of amino acids: Translated: 275; Mature: 275
Protein sequence:
>275_residues MREVRPFTNRRRVSAVKAGDRRVAIVTAAAAGIGKAIALRWCREGGCCVMADTDGEGLDAAVHELAESGAAVCGVAGDVC LSDVANSVVERALTEFGRLDTLFNVVGGSLARNVEEISEEQWRSQIDMNLGSVFQMSKPVIPLLRQGGGGSIVNVASTAG ILAENRCSAYSASKGGVVLLTKNMALDFARDNIRVNAIAPGGTRTPRIERFLAEHPEHASMMVDLCAMQRFAGPDEIAAP AVFLASPEASYITGAVLPVDGGMTAGVTFRAFEAV
Sequences:
>Translated_275_residues MREVRPFTNRRRVSAVKAGDRRVAIVTAAAAGIGKAIALRWCREGGCCVMADTDGEGLDAAVHELAESGAAVCGVAGDVC LSDVANSVVERALTEFGRLDTLFNVVGGSLARNVEEISEEQWRSQIDMNLGSVFQMSKPVIPLLRQGGGGSIVNVASTAG ILAENRCSAYSASKGGVVLLTKNMALDFARDNIRVNAIAPGGTRTPRIERFLAEHPEHASMMVDLCAMQRFAGPDEIAAP AVFLASPEASYITGAVLPVDGGMTAGVTFRAFEAV >Mature_275_residues MREVRPFTNRRRVSAVKAGDRRVAIVTAAAAGIGKAIALRWCREGGCCVMADTDGEGLDAAVHELAESGAAVCGVAGDVC LSDVANSVVERALTEFGRLDTLFNVVGGSLARNVEEISEEQWRSQIDMNLGSVFQMSKPVIPLLRQGGGGSIVNVASTAG ILAENRCSAYSASKGGVVLLTKNMALDFARDNIRVNAIAPGGTRTPRIERFLAEHPEHASMMVDLCAMQRFAGPDEIAAP AVFLASPEASYITGAVLPVDGGMTAGVTFRAFEAV
Specific function: Unknown
COG id: COG1028
COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI32483357, Length=242, Percent_Identity=33.8842975206612, Blast_Score=122, Evalue=4e-28, Organism=Homo sapiens, GI19923817, Length=250, Percent_Identity=33.6, Blast_Score=108, Evalue=6e-24, Organism=Homo sapiens, GI66933014, Length=252, Percent_Identity=35.3174603174603, Blast_Score=107, Evalue=8e-24, Organism=Homo sapiens, GI10190704, Length=249, Percent_Identity=31.7269076305221, Blast_Score=106, Evalue=2e-23, Organism=Homo sapiens, GI59889578, Length=235, Percent_Identity=32.3404255319149, Blast_Score=104, Evalue=9e-23, Organism=Homo sapiens, GI126723750, Length=245, Percent_Identity=31.0204081632653, Blast_Score=103, Evalue=2e-22, Organism=Homo sapiens, GI40254992, Length=247, Percent_Identity=34.8178137651822, Blast_Score=100, Evalue=2e-21, Organism=Homo sapiens, GI7705925, Length=246, Percent_Identity=31.3008130081301, Blast_Score=92, Evalue=5e-19, Organism=Homo sapiens, GI15277342, Length=250, Percent_Identity=28, Blast_Score=91, Evalue=1e-18, Organism=Homo sapiens, GI5031737, Length=244, Percent_Identity=28.6885245901639, Blast_Score=89, Evalue=3e-18, Organism=Homo sapiens, GI31542939, Length=268, Percent_Identity=27.9850746268657, Blast_Score=83, Evalue=3e-16, Organism=Homo sapiens, GI126723191, Length=178, Percent_Identity=31.4606741573034, Blast_Score=81, Evalue=8e-16, Organism=Homo sapiens, GI4504505, Length=222, Percent_Identity=29.7297297297297, Blast_Score=79, Evalue=3e-15, Organism=Homo sapiens, GI4758504, Length=259, Percent_Identity=30.1158301158301, Blast_Score=76, Evalue=3e-14, Organism=Homo sapiens, GI33667109, Length=185, Percent_Identity=29.7297297297297, Blast_Score=74, Evalue=1e-13, Organism=Homo sapiens, GI4503301, Length=220, Percent_Identity=24.0909090909091, Blast_Score=66, Evalue=3e-11, Organism=Escherichia coli, GI1789208, Length=245, Percent_Identity=32.6530612244898, Blast_Score=124, Evalue=8e-30, Organism=Escherichia coli, GI1787905, Length=246, Percent_Identity=32.1138211382114, Blast_Score=121, Evalue=4e-29, Organism=Escherichia coli, GI87082100, Length=249, Percent_Identity=33.7349397590361, Blast_Score=120, Evalue=9e-29, Organism=Escherichia coli, GI1790717, Length=243, Percent_Identity=29.6296296296296, Blast_Score=116, Evalue=1e-27, Organism=Escherichia coli, GI1787335, Length=244, Percent_Identity=33.1967213114754, Blast_Score=115, Evalue=3e-27, Organism=Escherichia coli, GI1788459, Length=257, Percent_Identity=31.5175097276265, Blast_Score=98, Evalue=5e-22, Organism=Escherichia coli, GI1789378, Length=258, Percent_Identity=29.4573643410853, Blast_Score=94, Evalue=9e-21, Organism=Escherichia coli, GI87082160, Length=244, Percent_Identity=28.2786885245902, Blast_Score=94, Evalue=1e-20, Organism=Escherichia coli, GI1786812, Length=252, Percent_Identity=31.7460317460317, Blast_Score=87, Evalue=9e-19, Organism=Escherichia coli, GI1787526, Length=254, Percent_Identity=26.3779527559055, Blast_Score=73, Evalue=2e-14, Organism=Escherichia coli, GI2367175, Length=260, Percent_Identity=30, Blast_Score=69, Evalue=3e-13, Organism=Escherichia coli, GI1789057, Length=253, Percent_Identity=25.6916996047431, Blast_Score=69, Evalue=3e-13, Organism=Escherichia coli, GI2367365, Length=245, Percent_Identity=26.9387755102041, Blast_Score=62, Evalue=6e-11, Organism=Caenorhabditis elegans, GI17561402, Length=249, Percent_Identity=35.7429718875502, Blast_Score=138, Evalue=2e-33, Organism=Caenorhabditis elegans, GI17560676, Length=247, Percent_Identity=34.412955465587, Blast_Score=137, Evalue=8e-33, Organism=Caenorhabditis elegans, GI25147288, Length=248, Percent_Identity=33.4677419354839, Blast_Score=113, Evalue=1e-25, Organism=Caenorhabditis elegans, GI17555706, Length=248, Percent_Identity=34.2741935483871, Blast_Score=112, Evalue=2e-25, Organism=Caenorhabditis elegans, GI17562910, Length=258, Percent_Identity=29.0697674418605, Blast_Score=97, Evalue=7e-21, Organism=Caenorhabditis elegans, GI17559104, Length=257, Percent_Identity=29.5719844357977, Blast_Score=97, Evalue=1e-20, Organism=Caenorhabditis elegans, GI17538480, Length=266, Percent_Identity=28.1954887218045, Blast_Score=94, Evalue=9e-20, Organism=Caenorhabditis elegans, GI17562904, Length=267, Percent_Identity=28.0898876404494, Blast_Score=93, Evalue=2e-19, Organism=Caenorhabditis elegans, GI17565030, Length=258, Percent_Identity=29.8449612403101, Blast_Score=92, Evalue=3e-19, Organism=Caenorhabditis elegans, GI71994604, Length=247, Percent_Identity=29.5546558704453, Blast_Score=91, Evalue=5e-19, Organism=Caenorhabditis elegans, GI17560332, Length=261, Percent_Identity=29.5019157088123, Blast_Score=91, Evalue=5e-19, Organism=Caenorhabditis elegans, GI115534694, Length=246, Percent_Identity=27.6422764227642, Blast_Score=87, Evalue=7e-18, Organism=Caenorhabditis elegans, GI17551412, Length=265, Percent_Identity=27.5471698113208, Blast_Score=86, Evalue=2e-17, Organism=Caenorhabditis elegans, GI71994600, Length=248, Percent_Identity=27.8225806451613, Blast_Score=84, Evalue=6e-17, Organism=Caenorhabditis elegans, GI17538182, Length=266, Percent_Identity=29.6992481203008, Blast_Score=84, Evalue=7e-17, Organism=Caenorhabditis elegans, GI72000259, Length=268, Percent_Identity=27.9850746268657, Blast_Score=83, Evalue=1e-16, Organism=Caenorhabditis elegans, GI17562908, Length=258, Percent_Identity=28.2945736434109, Blast_Score=83, Evalue=2e-16, Organism=Caenorhabditis elegans, GI193204405, Length=269, Percent_Identity=27.1375464684015, Blast_Score=81, Evalue=5e-16, Organism=Caenorhabditis elegans, GI17562990, Length=260, Percent_Identity=26.1538461538462, Blast_Score=81, Evalue=6e-16, Organism=Caenorhabditis elegans, GI17531453, Length=268, Percent_Identity=29.4776119402985, Blast_Score=81, Evalue=7e-16, Organism=Caenorhabditis elegans, GI17560150, Length=263, Percent_Identity=25.4752851711027, Blast_Score=80, Evalue=9e-16, Organism=Caenorhabditis elegans, GI17560220, Length=264, Percent_Identity=26.1363636363636, Blast_Score=80, Evalue=1e-15, Organism=Caenorhabditis elegans, GI17562906, Length=258, Percent_Identity=27.5193798449612, Blast_Score=78, Evalue=5e-15, Organism=Caenorhabditis elegans, GI17538486, Length=257, Percent_Identity=27.6264591439689, Blast_Score=76, Evalue=2e-14, Organism=Caenorhabditis elegans, GI17563726, Length=261, Percent_Identity=27.5862068965517, Blast_Score=76, Evalue=2e-14, Organism=Caenorhabditis elegans, GI17536025, Length=246, Percent_Identity=24.390243902439, Blast_Score=75, Evalue=5e-14, Organism=Caenorhabditis elegans, GI17544670, Length=261, Percent_Identity=23.3716475095785, Blast_Score=71, Evalue=7e-13, Organism=Caenorhabditis elegans, GI17568967, Length=197, Percent_Identity=27.9187817258883, Blast_Score=71, Evalue=8e-13, Organism=Caenorhabditis elegans, GI17536651, Length=248, Percent_Identity=23.7903225806452, Blast_Score=68, Evalue=5e-12, Organism=Caenorhabditis elegans, GI17508895, Length=250, Percent_Identity=20.8, Blast_Score=65, Evalue=3e-11, Organism=Saccharomyces cerevisiae, GI6322861, Length=252, Percent_Identity=28.5714285714286, Blast_Score=100, Evalue=4e-22, Organism=Saccharomyces cerevisiae, GI6324126, Length=252, Percent_Identity=29.3650793650794, Blast_Score=83, Evalue=4e-17, Organism=Saccharomyces cerevisiae, GI6323882, Length=191, Percent_Identity=28.2722513089005, Blast_Score=70, Evalue=5e-13, Organism=Drosophila melanogaster, GI21355319, Length=250, Percent_Identity=35.6, Blast_Score=129, Evalue=2e-30, Organism=Drosophila melanogaster, GI24644339, Length=255, Percent_Identity=32.156862745098, Blast_Score=109, Evalue=2e-24, Organism=Drosophila melanogaster, GI23397609, Length=249, Percent_Identity=32.5301204819277, Blast_Score=109, Evalue=2e-24, Organism=Drosophila melanogaster, GI21357041, Length=255, Percent_Identity=32.9411764705882, Blast_Score=105, Evalue=2e-23, Organism=Drosophila melanogaster, GI28571526, Length=251, Percent_Identity=33.4661354581673, Blast_Score=103, Evalue=9e-23, Organism=Drosophila melanogaster, GI24644337, Length=249, Percent_Identity=35.3413654618474, Blast_Score=94, Evalue=7e-20, Organism=Drosophila melanogaster, GI24639444, Length=246, Percent_Identity=29.2682926829268, Blast_Score=93, Evalue=2e-19, Organism=Drosophila melanogaster, GI24643142, Length=246, Percent_Identity=26.8292682926829, Blast_Score=84, Evalue=1e-16, Organism=Drosophila melanogaster, GI18859837, Length=190, Percent_Identity=31.0526315789474, Blast_Score=83, Evalue=3e-16, Organism=Drosophila melanogaster, GI17737361, Length=255, Percent_Identity=29.4117647058824, Blast_Score=80, Evalue=1e-15, Organism=Drosophila melanogaster, GI161076933, Length=203, Percent_Identity=27.5862068965517, Blast_Score=68, Evalue=7e-12, Organism=Drosophila melanogaster, GI24584748, Length=203, Percent_Identity=27.5862068965517, Blast_Score=67, Evalue=9e-12, Organism=Drosophila melanogaster, GI21357673, Length=188, Percent_Identity=26.063829787234, Blast_Score=65, Evalue=5e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR011284 - InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: =1.1.1.100 [H]
Molecular weight: Translated: 28854; Mature: 28854
Theoretical pI: Translated: 5.42; Mature: 5.42
Prosite motif: PS00061 ADH_SHORT ; PS00445 FGGY_KINASES_2
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
2.5 %Cys (Translated Protein) 3.3 %Met (Translated Protein) 5.8 %Cys+Met (Translated Protein) 2.5 %Cys (Mature Protein) 3.3 %Met (Mature Protein) 5.8 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MREVRPFTNRRRVSAVKAGDRRVAIVTAAAAGIGKAIALRWCREGGCCVMADTDGEGLDA CCCCCCCCCCHHHHHEECCCCEEEEEEECHHHHHHHHHHHHHCCCCEEEEECCCCCCHHH AVHELAESGAAVCGVAGDVCLSDVANSVVERALTEFGRLDTLFNVVGGSLARNVEEISEE HHHHHHHCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH QWRSQIDMNLGSVFQMSKPVIPLLRQGGGGSIVNVASTAGILAENRCSAYSASKGGVVLL HHHHHHCCCHHHHHHHCCCHHHHHHCCCCCCEEEHHHHHHHHHCCCCCCCCCCCCCEEEE TKNMALDFARDNIRVNAIAPGGTRTPRIERFLAEHPEHASMMVDLCAMQRFAGPDEIAAP ECCCEEEEECCCEEEEEECCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCHHCCC AVFLASPEASYITGAVLPVDGGMTAGVTFRAFEAV EEEEECCCCCHHEEEEEECCCCCCCCEEEEEEECC >Mature Secondary Structure MREVRPFTNRRRVSAVKAGDRRVAIVTAAAAGIGKAIALRWCREGGCCVMADTDGEGLDA CCCCCCCCCCHHHHHEECCCCEEEEEEECHHHHHHHHHHHHHCCCCEEEEECCCCCCHHH AVHELAESGAAVCGVAGDVCLSDVANSVVERALTEFGRLDTLFNVVGGSLARNVEEISEE HHHHHHHCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH QWRSQIDMNLGSVFQMSKPVIPLLRQGGGGSIVNVASTAGILAENRCSAYSASKGGVVLL HHHHHHCCCHHHHHHHCCCHHHHHHCCCCCCEEEHHHHHHHHHCCCCCCCCCCCCCEEEE TKNMALDFARDNIRVNAIAPGGTRTPRIERFLAEHPEHASMMVDLCAMQRFAGPDEIAAP ECCCEEEEECCCEEEEEECCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCHHCCC AVFLASPEASYITGAVLPVDGGMTAGVTFRAFEAV EEEEECCCCCHHEEEEEECCCCCCCCEEEEEEECC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 10360571 [H]