Click here to switch to the map view.

The map label for this gene is ilvY [H]

Identifier: 119776415

GI number: 119776415

Start: 3900776

End: 3901654

Strand: Direct

Name: ilvY [H]

Synonym: Sama_3283

Alternate gene names: 119776415

Gene position: 3900776-3901654 (Clockwise)

Preceding gene: 119776407

Following gene: 119776417

Centisome position: 90.59

GC content: 56.43

Gene sequence:

>879_bases
ATGGATATTCGTGAAATAAAGCTGTTTTTAAACCTGTGTGACACCCTGCAGTTTGCCCGCACGGCGGAGCAGATGCATGT
GAGCCCATCCACCTTAAGCCGTGCCATGCAACGACTGGAAGAAGAAGCCGGTACCCGACTGTTTGAGCGCGACAATCGCA
GCGTGAGTCTGACCTCGGCCGGCGTGGAATTTCGCCGATTTGCGCAGGATATGATGAATAGCTGGGAGCAGCTGGTAAGC
CGAATCGACCCCAATCAATTGCAACTAAAAGGCAGGCTGAATCTCTATTGCTCGGTCACTGCAGCTTACAGTCACCTCCC
CAAGCTGCTGGACAGATTTCGCCGCGAGCACCCCCTGGTAGAAATCGTGCTCAATACCGGTGATGCTGCCAACGCGGTGG
GGGAGGTTCAACAAAACCGCGCCGACATCGCCATTGCCGCCTTGCCAGAGCCTTTTCCCGATAACCTGCATTTTTCGCCG
ATTGAAACCATTCCCCTGAGTATCATTGCACCCCAGGTGGCGTGCCGCGCGCGGGAGCTGCTCGGTGAAGAGACCGTTCC
CTGGGACAAGCTGCCCTTTATCATTCCGGAGCACGGTCCCGGAAGACGCCGCGCCGATGCCTGGTTCAAAGCCATGGGGA
TCAATGCCAACATATACGCCAAGGTGTCGGGACACGAGGCCATTATCTCCATGGTGGCACTGGGCTGCGGCGTGAGTATC
ACCCCTGAAGTGGTGATTCAGCACAGTCCGGTGCGCGATCGCATTGCGCTTATTCCAAGCCCGGTGGCCATTGCACCCTT
TGAGCTGGGATGTTGTTGCAAGACCAAACGCAGGGACGACCCGCTGATTGCTGCCTTTCTCGCGTGCATTGACTATTAA

Upstream 100 bases:

>100_bases
TATAAACGAAACTTTATATTTCAATTTTTGCAACAAACTTACCCTGGAAAGGTTTTGATGTGGCGTCCGGCATAGCTATC
AGGACACCTGTGAGGTTGGC

Downstream 100 bases:

>100_bases
GTTGAACCCCAACGAAAAAGGCCGCTTAATGCGGCCTTTTTTCATGTTGGTCGTTACTGATCCTCAGCACCGGGTGGCAA
CTCCACCTTGGTCACCAGCA

Product: DNA-binding transcriptional regulator IlvY

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 292; Mature: 292

Protein sequence:

>292_residues
MDIREIKLFLNLCDTLQFARTAEQMHVSPSTLSRAMQRLEEEAGTRLFERDNRSVSLTSAGVEFRRFAQDMMNSWEQLVS
RIDPNQLQLKGRLNLYCSVTAAYSHLPKLLDRFRREHPLVEIVLNTGDAANAVGEVQQNRADIAIAALPEPFPDNLHFSP
IETIPLSIIAPQVACRARELLGEETVPWDKLPFIIPEHGPGRRRADAWFKAMGINANIYAKVSGHEAIISMVALGCGVSI
TPEVVIQHSPVRDRIALIPSPVAIAPFELGCCCKTKRRDDPLIAAFLACIDY

Sequences:

>Translated_292_residues
MDIREIKLFLNLCDTLQFARTAEQMHVSPSTLSRAMQRLEEEAGTRLFERDNRSVSLTSAGVEFRRFAQDMMNSWEQLVS
RIDPNQLQLKGRLNLYCSVTAAYSHLPKLLDRFRREHPLVEIVLNTGDAANAVGEVQQNRADIAIAALPEPFPDNLHFSP
IETIPLSIIAPQVACRARELLGEETVPWDKLPFIIPEHGPGRRRADAWFKAMGINANIYAKVSGHEAIISMVALGCGVSI
TPEVVIQHSPVRDRIALIPSPVAIAPFELGCCCKTKRRDDPLIAAFLACIDY
>Mature_292_residues
MDIREIKLFLNLCDTLQFARTAEQMHVSPSTLSRAMQRLEEEAGTRLFERDNRSVSLTSAGVEFRRFAQDMMNSWEQLVS
RIDPNQLQLKGRLNLYCSVTAAYSHLPKLLDRFRREHPLVEIVLNTGDAANAVGEVQQNRADIAIAALPEPFPDNLHFSP
IETIPLSIIAPQVACRARELLGEETVPWDKLPFIIPEHGPGRRRADAWFKAMGINANIYAKVSGHEAIISMVALGCGVSI
TPEVVIQHSPVRDRIALIPSPVAIAPFELGCCCKTKRRDDPLIAAFLACIDY

Specific function: This protein activates the transcription of the ilvC gene in the presence of acetolactate or acetohydroxybutyrate. IlvY is also a negative regulator of its own expression [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790208, Length=289, Percent_Identity=51.2110726643599, Blast_Score=279, Evalue=1e-76,
Organism=Escherichia coli, GI1788748, Length=248, Percent_Identity=25.4032258064516, Blast_Score=85, Evalue=4e-18,
Organism=Escherichia coli, GI1787806, Length=267, Percent_Identity=22.4719101123595, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI145693105, Length=266, Percent_Identity=23.3082706766917, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI2367136, Length=279, Percent_Identity=21.505376344086, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1787601, Length=162, Percent_Identity=24.6913580246914, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1790399, Length=259, Percent_Identity=22.7799227799228, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1787530, Length=259, Percent_Identity=23.5521235521236, Blast_Score=68, Evalue=6e-13,
Organism=Escherichia coli, GI1787879, Length=252, Percent_Identity=25.7936507936508, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1788887, Length=249, Percent_Identity=24.8995983935743, Blast_Score=64, Evalue=8e-12,
Organism=Escherichia coli, GI145693193, Length=129, Percent_Identity=28.6821705426357, Blast_Score=61, Evalue=1e-10,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 32595; Mature: 32595

Theoretical pI: Translated: 6.62; Mature: 6.62

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDIREIKLFLNLCDTLQFARTAEQMHVSPSTLSRAMQRLEEEAGTRLFERDNRSVSLTSA
CCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCHHHHCCCCEEEEECC
GVEFRRFAQDMMNSWEQLVSRIDPNQLQLKGRLNLYCSVTAAYSHLPKLLDRFRREHPLV
CHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECEEEEEEHHHHHHHHHHHHHHHHHCCCEE
EIVLNTGDAANAVGEVQQNRADIAIAALPEPFPDNLHFSPIETIPLSIIAPQVACRAREL
EEEEECCCHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCHHHCCHHHHHHHHHHHHHHH
LGEETVPWDKLPFIIPEHGPGRRRADAWFKAMGINANIYAKVSGHEAIISMVALGCGVSI
HCCCCCCCCCCCEEECCCCCCCCHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHCCCCC
TPEVVIQHSPVRDRIALIPSPVAIAPFELGCCCKTKRRDDPLIAAFLACIDY
CHHEEEECCCCHHHHEECCCCCEECCCCCCCCCCCCCCCCHHHHHHHHHHCC
>Mature Secondary Structure
MDIREIKLFLNLCDTLQFARTAEQMHVSPSTLSRAMQRLEEEAGTRLFERDNRSVSLTSA
CCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCHHHHCCCCEEEEECC
GVEFRRFAQDMMNSWEQLVSRIDPNQLQLKGRLNLYCSVTAAYSHLPKLLDRFRREHPLV
CHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECEEEEEEHHHHHHHHHHHHHHHHHCCCEE
EIVLNTGDAANAVGEVQQNRADIAIAALPEPFPDNLHFSPIETIPLSIIAPQVACRAREL
EEEEECCCHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCHHHCCHHHHHHHHHHHHHHH
LGEETVPWDKLPFIIPEHGPGRRRADAWFKAMGINANIYAKVSGHEAIISMVALGCGVSI
HCCCCCCCCCCCEEECCCCCCCCHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHCCCCC
TPEVVIQHSPVRDRIALIPSPVAIAPFELGCCCKTKRRDDPLIAAFLACIDY
CHHEEEECCCCHHHHEECCCCCEECCCCCCCCCCCCCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3003115; 1379743; 9278503; 3550695 [H]