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The map label for this gene is cysJ [H]

Identifier: 119775971

GI number: 119775971

Start: 3377153

End: 3378961

Strand: Reverse

Name: cysJ [H]

Synonym: Sama_2839

Alternate gene names: 119775971

Gene position: 3378961-3377153 (Counterclockwise)

Preceding gene: 119775979

Following gene: 119775970

Centisome position: 78.47

GC content: 54.67

Gene sequence:

>1809_bases
ATGCTGTTAAAAGAATTATCCTCCCTCGCGTCTCCGCTCAGTGCCGAGCAGGTCGACAAGCTCAAGAACCTGACCTTTGA
GCTCAACGCCGTGCAACTGGCCTGGGTCAGTGGTTATCTGGCCGCAAACGCGCAATTTGCTGCTGGGGGGGCTATTGCTG
CAGCACCCGCTGCCCAGGAAGCCGCTACCTTAACGGTGCTTTATGCATCGCAGACCGGCAATGCCAAAGGCGTGGCCAGT
AAAATCAAAGCGGCGGCAGAAAGCCGTGGCTTGGCTGTGCAGTTGCAGGACATTGCCTCGTATAAAACCAATGCGTTGGC
AAAAGAAAAATTCCTAATCATTGTTGCCTCGACCTACGGCGAGGGTGAACCACCCGAGAGCGCGGTGAGTTTCTATAAGT
TCCTGTTTGGTAAAAAAGCACCCAAGTTACCCGAGCTGCAATTTGCCGTGTTGGGCCTTGGCGATACCAGCTATGAGTTT
TTCTGCAAAACCGCCACTGACTTTGACAGCCAACTGGCGGCATTAGGTGCAAAACGCCTGCATGAACCGGCCCTGCTGGA
TGTTGATTATGGCGACGGCGCGAAAAACTGGCAGGAAGCTGCCTTGGATGTGTTTGCACCGCTGCTTAAAGCATCAGGCG
CCGGTAGCGAGAAAGTGATTGCATGGCCAGGCGCGACTGGCACCGCGGGTAGCCACAGCCAGTATGATAAGCAAAACCCA
GCCACCGCTGAGTTAAGTGTTAATCAAAAGATCACGGCGCGTAATTCCACCAAAGACGTGCGTCATATTGAGATTTCGCT
GGAAGGCACCGGCCTGACTTATCAGCCGGGTGATGCGTTAGGGGTGTATTTCCGCAACGCACCTGAGCTTGTCGCCAGCG
TGCTGGCCGCCACGGGGTTAACCGGCAGCGAGCAGGTTGAGCTGTCTGGTAAAACCTTAACGCTGCAAGCGGCGTTAACC
GACGAGCTGGAGCTCACCCAAGCCTACCCGTCGCTGGTGACCAAGTACGCAGAGGTGAGCAACAATGCCGAGCTGCAAGC
GCTTGGCGCCAACAAAGACGCGCTGCGCGCTTATCTGGCCGATAAGCAAAGCGCCGATGTGATTGTGCAAAACCCTGCCA
ACATCAGCGCACAGCAGCTGGTGGACAGCCTGCGCAAAGTGCAGCCACGCCTGTATTCCATCGCCTCAAGCCAAGCCGAA
GTGGGCGAAGAAGTGCATTTAACCGTGGGCGTGGTGCGTTACGATGCCTTTGGCAGCACCCATTTGGGTGGGGCGTCAGG
CTTTTTGGCTGAGCGCCTTGCCGAAGGTGAGGCAGTGAAAGTCTTTGTTGAACACAATGACAACTTCCGCCTGCCAAACC
ACGACACACCTGTGTTGATGATTGGCCCCGGCACAGGTATTGCGCCATTCAGGGCGTTCTTGCAAGAGCGTGATAACGCA
GGTGCGACTGGCCAAAACTGGCTGTTCTTCGGTAACCCGCATTTCACCCGTGATTTCTTATATCAGGTAGAGCTGCAAGA
CTACTTGAAGCGTGGTGTGTTAACCCACCTGGATGTGGCATTCAGCCGCGACCAGGCGCAAAAAGTGTATGTGCAGGACA
AACTGACCGCCAAAGGCGCCGAAGTCTGGTCTTGGCTGCAACAAGGTGCTCACTTGTATATTTGTGGTGACGGCAACCGG
ATGGCCAAAGATGTGCATCAGGCGTTATTACACATTGCCCAAACCCACGGTGGCTTGTCTGCCGAAGCAGCCGACGAATA
TTTTGAAGAGTTACGCGCGAACAAACGTTATCAGAAGGATGTTTATTAA

Upstream 100 bases:

>100_bases
GCATATTCCCAAAGAGAATAAAAAATTAAATTTTATTCTTTTTTGCTTGCAGCAAAGGGCACTAAGCTAGCATGCAATAA
AATGTCACTGGGTCGTCCTC

Downstream 100 bases:

>100_bases
TGAGCCAGTATCCAATTAAGCCTGAACTGCAGGTGCAGGGCCAGTTGTCTGATAACGAGCGCCTGAAAGCTGAAAGCAAC
CACTTGCGTGGCACTATCAC

Product: sulfite reductase subunit alpha

Products: NA

Alternate protein names: SiR-FP [H]

Number of amino acids: Translated: 602; Mature: 602

Protein sequence:

>602_residues
MLLKELSSLASPLSAEQVDKLKNLTFELNAVQLAWVSGYLAANAQFAAGGAIAAAPAAQEAATLTVLYASQTGNAKGVAS
KIKAAAESRGLAVQLQDIASYKTNALAKEKFLIIVASTYGEGEPPESAVSFYKFLFGKKAPKLPELQFAVLGLGDTSYEF
FCKTATDFDSQLAALGAKRLHEPALLDVDYGDGAKNWQEAALDVFAPLLKASGAGSEKVIAWPGATGTAGSHSQYDKQNP
ATAELSVNQKITARNSTKDVRHIEISLEGTGLTYQPGDALGVYFRNAPELVASVLAATGLTGSEQVELSGKTLTLQAALT
DELELTQAYPSLVTKYAEVSNNAELQALGANKDALRAYLADKQSADVIVQNPANISAQQLVDSLRKVQPRLYSIASSQAE
VGEEVHLTVGVVRYDAFGSTHLGGASGFLAERLAEGEAVKVFVEHNDNFRLPNHDTPVLMIGPGTGIAPFRAFLQERDNA
GATGQNWLFFGNPHFTRDFLYQVELQDYLKRGVLTHLDVAFSRDQAQKVYVQDKLTAKGAEVWSWLQQGAHLYICGDGNR
MAKDVHQALLHIAQTHGGLSAEAADEYFEELRANKRYQKDVY

Sequences:

>Translated_602_residues
MLLKELSSLASPLSAEQVDKLKNLTFELNAVQLAWVSGYLAANAQFAAGGAIAAAPAAQEAATLTVLYASQTGNAKGVAS
KIKAAAESRGLAVQLQDIASYKTNALAKEKFLIIVASTYGEGEPPESAVSFYKFLFGKKAPKLPELQFAVLGLGDTSYEF
FCKTATDFDSQLAALGAKRLHEPALLDVDYGDGAKNWQEAALDVFAPLLKASGAGSEKVIAWPGATGTAGSHSQYDKQNP
ATAELSVNQKITARNSTKDVRHIEISLEGTGLTYQPGDALGVYFRNAPELVASVLAATGLTGSEQVELSGKTLTLQAALT
DELELTQAYPSLVTKYAEVSNNAELQALGANKDALRAYLADKQSADVIVQNPANISAQQLVDSLRKVQPRLYSIASSQAE
VGEEVHLTVGVVRYDAFGSTHLGGASGFLAERLAEGEAVKVFVEHNDNFRLPNHDTPVLMIGPGTGIAPFRAFLQERDNA
GATGQNWLFFGNPHFTRDFLYQVELQDYLKRGVLTHLDVAFSRDQAQKVYVQDKLTAKGAEVWSWLQQGAHLYICGDGNR
MAKDVHQALLHIAQTHGGLSAEAADEYFEELRANKRYQKDVY
>Mature_602_residues
MLLKELSSLASPLSAEQVDKLKNLTFELNAVQLAWVSGYLAANAQFAAGGAIAAAPAAQEAATLTVLYASQTGNAKGVAS
KIKAAAESRGLAVQLQDIASYKTNALAKEKFLIIVASTYGEGEPPESAVSFYKFLFGKKAPKLPELQFAVLGLGDTSYEF
FCKTATDFDSQLAALGAKRLHEPALLDVDYGDGAKNWQEAALDVFAPLLKASGAGSEKVIAWPGATGTAGSHSQYDKQNP
ATAELSVNQKITARNSTKDVRHIEISLEGTGLTYQPGDALGVYFRNAPELVASVLAATGLTGSEQVELSGKTLTLQAALT
DELELTQAYPSLVTKYAEVSNNAELQALGANKDALRAYLADKQSADVIVQNPANISAQQLVDSLRKVQPRLYSIASSQAE
VGEEVHLTVGVVRYDAFGSTHLGGASGFLAERLAEGEAVKVFVEHNDNFRLPNHDTPVLMIGPGTGIAPFRAFLQERDNA
GATGQNWLFFGNPHFTRDFLYQVELQDYLKRGVLTHLDVAFSRDQAQKVYVQDKLTAKGAEVWSWLQQGAHLYICGDGNR
MAKDVHQALLHIAQTHGGLSAEAADEYFEELRANKRYQKDVY

Specific function: Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow f

COG id: COG0369

COG function: function code P; Sulfite reductase, alpha subunit (flavoprotein)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 flavodoxin-like domain [H]

Homologues:

Organism=Homo sapiens, GI7657393, Length=610, Percent_Identity=30.655737704918, Blast_Score=226, Evalue=5e-59,
Organism=Homo sapiens, GI221316709, Length=610, Percent_Identity=30.655737704918, Blast_Score=221, Evalue=1e-57,
Organism=Homo sapiens, GI127139033, Length=603, Percent_Identity=28.0265339966833, Blast_Score=221, Evalue=2e-57,
Organism=Homo sapiens, GI221316705, Length=619, Percent_Identity=30.2100161550889, Blast_Score=219, Evalue=7e-57,
Organism=Homo sapiens, GI24041029, Length=595, Percent_Identity=31.4285714285714, Blast_Score=211, Evalue=1e-54,
Organism=Homo sapiens, GI221316707, Length=533, Percent_Identity=31.5196998123827, Blast_Score=198, Evalue=1e-50,
Organism=Homo sapiens, GI10835173, Length=652, Percent_Identity=28.8343558282209, Blast_Score=181, Evalue=1e-45,
Organism=Homo sapiens, GI40254422, Length=658, Percent_Identity=29.483282674772, Blast_Score=175, Evalue=1e-43,
Organism=Homo sapiens, GI169790956, Length=420, Percent_Identity=30.952380952381, Blast_Score=169, Evalue=7e-42,
Organism=Homo sapiens, GI169790958, Length=420, Percent_Identity=30.952380952381, Blast_Score=169, Evalue=9e-42,
Organism=Escherichia coli, GI1789123, Length=597, Percent_Identity=52.0938023450586, Blast_Score=593, Evalue=1e-170,
Organism=Caenorhabditis elegans, GI17554134, Length=597, Percent_Identity=31.3232830820771, Blast_Score=250, Evalue=2e-66,
Organism=Caenorhabditis elegans, GI17566446, Length=586, Percent_Identity=26.2798634812287, Blast_Score=145, Evalue=6e-35,
Organism=Caenorhabditis elegans, GI17531441, Length=405, Percent_Identity=25.4320987654321, Blast_Score=92, Evalue=7e-19,
Organism=Caenorhabditis elegans, GI32563863, Length=125, Percent_Identity=33.6, Blast_Score=66, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6321832, Length=660, Percent_Identity=28.6363636363636, Blast_Score=190, Evalue=4e-49,
Organism=Saccharomyces cerevisiae, GI6321143, Length=385, Percent_Identity=30.6493506493506, Blast_Score=144, Evalue=3e-35,
Organism=Saccharomyces cerevisiae, GI6325305, Length=632, Percent_Identity=22.9430379746835, Blast_Score=143, Evalue=7e-35,
Organism=Saccharomyces cerevisiae, GI6322597, Length=137, Percent_Identity=33.5766423357664, Blast_Score=64, Evalue=8e-11,
Organism=Drosophila melanogaster, GI17137192, Length=613, Percent_Identity=31.1582381729201, Blast_Score=234, Evalue=1e-61,
Organism=Drosophila melanogaster, GI24582192, Length=517, Percent_Identity=31.1411992263056, Blast_Score=207, Evalue=1e-53,
Organism=Drosophila melanogaster, GI24660907, Length=596, Percent_Identity=28.5234899328859, Blast_Score=174, Evalue=1e-43,
Organism=Drosophila melanogaster, GI24660903, Length=596, Percent_Identity=28.5234899328859, Blast_Score=174, Evalue=1e-43,
Organism=Drosophila melanogaster, GI24583543, Length=671, Percent_Identity=25.9314456035768, Blast_Score=161, Evalue=1e-39,
Organism=Drosophila melanogaster, GI78706876, Length=671, Percent_Identity=25.9314456035768, Blast_Score=161, Evalue=1e-39,
Organism=Drosophila melanogaster, GI78706872, Length=671, Percent_Identity=25.9314456035768, Blast_Score=161, Evalue=1e-39,
Organism=Drosophila melanogaster, GI24647438, Length=403, Percent_Identity=23.3250620347395, Blast_Score=77, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010199
- InterPro:   IPR003097
- InterPro:   IPR017927
- InterPro:   IPR001094
- InterPro:   IPR008254
- InterPro:   IPR001709
- InterPro:   IPR023173
- InterPro:   IPR001433
- InterPro:   IPR017938 [H]

Pfam domain/function: PF00667 FAD_binding_1; PF00258 Flavodoxin_1; PF00175 NAD_binding_1 [H]

EC number: =1.8.1.2 [H]

Molecular weight: Translated: 64765; Mature: 64765

Theoretical pI: Translated: 5.37; Mature: 5.37

Prosite motif: PS50902 FLAVODOXIN_LIKE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
0.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
0.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLKELSSLASPLSAEQVDKLKNLTFELNAVQLAWVSGYLAANAQFAAGGAIAAAPAAQE
CCHHHHHHHHCCCCHHHHHHHHCCEEEEEEEEEEEEHHEHCCCCEECCCCCEEECCCCCC
AATLTVLYASQTGNAKGVASKIKAAAESRGLAVQLQDIASYKTNALAKEKFLIIVASTYG
CEEEEEEEEECCCCCCHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHCCCEEEEEEEECCC
EGEPPESAVSFYKFLFGKKAPKLPELQFAVLGLGDTSYEFFCKTATDFDSQLAALGAKRL
CCCCHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCEEEEEECCCCHHHHHHHHHHHHC
HEPALLDVDYGDGAKNWQEAALDVFAPLLKASGAGSEKVIAWPGATGTAGSHSQYDKQNP
CCCCEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCCCCCCCCC
ATAELSVNQKITARNSTKDVRHIEISLEGTGLTYQPGDALGVYFRNAPELVASVLAATGL
CEEEEEECCEEECCCCCCCEEEEEEEEECCCEEECCCCCEEEEECCCHHHHHHHHHHCCC
TGSEQVELSGKTLTLQAALTDELELTQAYPSLVTKYAEVSNNAELQALGANKDALRAYLA
CCCCEEEECCCEEEEEEECCCHHHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHC
DKQSADVIVQNPANISAQQLVDSLRKVQPRLYSIASSQAEVGEEVHLTVGVVRYDAFGST
CCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCHHHCCCEEEEEEEEEEEECCCCC
HLGGASGFLAERLAEGEAVKVFVEHNDNFRLPNHDTPVLMIGPGTGIAPFRAFLQERDNA
CCCCCHHHHHHHHCCCCEEEEEEEECCCCCCCCCCCCEEEEECCCCHHHHHHHHHHCCCC
GATGQNWLFFGNPHFTRDFLYQVELQDYLKRGVLTHLDVAFSRDQAQKVYVQDKLTAKGA
CCCCCCEEEECCCCCCHHHHEEEHHHHHHHCCCHHHHHHHHCCCCHHEEEEEHHHCCCHH
EVWSWLQQGAHLYICGDGNRMAKDVHQALLHIAQTHGGLSAEAADEYFEELRANKRYQKD
HHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCHHCC
VY
CC
>Mature Secondary Structure
MLLKELSSLASPLSAEQVDKLKNLTFELNAVQLAWVSGYLAANAQFAAGGAIAAAPAAQE
CCHHHHHHHHCCCCHHHHHHHHCCEEEEEEEEEEEEHHEHCCCCEECCCCCEEECCCCCC
AATLTVLYASQTGNAKGVASKIKAAAESRGLAVQLQDIASYKTNALAKEKFLIIVASTYG
CEEEEEEEEECCCCCCHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHCCCEEEEEEEECCC
EGEPPESAVSFYKFLFGKKAPKLPELQFAVLGLGDTSYEFFCKTATDFDSQLAALGAKRL
CCCCHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCEEEEEECCCCHHHHHHHHHHHHC
HEPALLDVDYGDGAKNWQEAALDVFAPLLKASGAGSEKVIAWPGATGTAGSHSQYDKQNP
CCCCEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCCCCCCCCC
ATAELSVNQKITARNSTKDVRHIEISLEGTGLTYQPGDALGVYFRNAPELVASVLAATGL
CEEEEEECCEEECCCCCCCEEEEEEEEECCCEEECCCCCEEEEECCCHHHHHHHHHHCCC
TGSEQVELSGKTLTLQAALTDELELTQAYPSLVTKYAEVSNNAELQALGANKDALRAYLA
CCCCEEEECCCEEEEEEECCCHHHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHC
DKQSADVIVQNPANISAQQLVDSLRKVQPRLYSIASSQAEVGEEVHLTVGVVRYDAFGST
CCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCHHHCCCEEEEEEEEEEEECCCCC
HLGGASGFLAERLAEGEAVKVFVEHNDNFRLPNHDTPVLMIGPGTGIAPFRAFLQERDNA
CCCCCHHHHHHHHCCCCEEEEEEEECCCCCCCCCCCCEEEEECCCCHHHHHHHHHHCCCC
GATGQNWLFFGNPHFTRDFLYQVELQDYLKRGVLTHLDVAFSRDQAQKVYVQDKLTAKGA
CCCCCCEEEECCCCCCHHHHEEEHHHHHHHCCCHHHHHHHHCCCCHHEEEEEHHHCCCHH
EVWSWLQQGAHLYICGDGNRMAKDVHQALLHIAQTHGGLSAEAADEYFEELRANKRYQKD
HHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCHHCC
VY
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA