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The map label for this gene is sdaC [H]

Identifier: 119775904

GI number: 119775904

Start: 3312408

End: 3313724

Strand: Reverse

Name: sdaC [H]

Synonym: Sama_2772

Alternate gene names: 119775904

Gene position: 3313724-3312408 (Counterclockwise)

Preceding gene: 119775905

Following gene: 119775903

Centisome position: 76.95

GC content: 55.28

Gene sequence:

>1317_bases
ATGTCCAACGAAACCATCACAGCCCCTGCCACCCAGGCAAGCATCTCTTCCACCGTTTCACAGCCCCACAAAGCCACGCC
CAACAATGCCATGCCCTGGACGGCGCAGGATACCACCTGGATGCTGAGCCTGTTTGGCACCGCCGTGGGCGCAGGCATTT
TATTTTTGCCCATTAATGCCGGTATGGGAGGCTTCTGGCCACTGGTGGTGATGGCGCTTTTGATTGGTCCCATGACGTAT
CTCGCCCACCGGGGGCTGTCGCGTTTTGTGTGCTCTTCATCCATTGCCGGAAGCGATATCACCCAGGTGGTGGAAGAGCA
TTTTGGCAAGGGCGCAGGTAAAGCCATTACTGTGCTGTATTTCTTCGCAATTTATCCCATAGTGCTCATCTATGGTGTGG
GCATTACCAATGTGGTCGACAGCTTTATGGTCAACCAGCTTGGCTTGGAGTCGCTGCCGCGCTGGCTGCTTTCGGGCGTA
CTTATCCTCGGCATGATGTCGGTGATGGTGGCCGGTGAAAAGATAATGCTCAAGGTGACCCAGTTTTTGGTGTACCCCCT
GGTGGCGATTCTTGCCTTTATGTCGCTGTACCTGATGCCTAACTGGAACCTGGCCGCCGTAAAGGAGGTCCCTGCCGTTG
GTGACTTCCTCGGCACCATCTGGCTGACTATTCCCGTGCTCATTTTTGCGTTTAACCACTCGCCCGCCATCAGTCAGTTT
GCGGTATCACTTAAGCGCGACCATGGCAGCAATGCGTCCCGCAAGGCCGATATCATCCTGCGCAACACCGCCATGATGCT
GGTGGGCTTTGTGATGCTGTTTGTGTTCTCCTGCGTGCTGTCGTTAAGCCCGGCGCAGCTGGCCGAGGCCAAGAGCCAGA
ACCTGCCGATTCTGTCGTACCTCGCCAACGTGTTCGACAGTGGTTTTGTCAGCTACTTTGGCCCCTTCATTGCCTTCGTG
GCCATAGTGTCTTCCTTCTTCGGCCACTACATGGGCGCCAGCGAAGGTATGAGCGGCATTATCAAGAAGCAGCTTGAAGG
TAAAGGTAAACCAGTGGATGAAGGCAAACTGAACCGCTTTATTCTGGGCTTTATGTTCCTGACCATCTGGGCGGTTGCCG
TGATTAATCCCAGTATCCTCGGCATGATTGAAGCCCTCGGTGGCCCCATCATTGCCGCCATCCTGTACCTGATGCCCATG
TACGCCGTGTATCGGGTGCCAGCGCTCAAAGCCTACCGTGGCCGCATCAGCAATATCTTCGTGATCATTGCCGGTTTACT
GTCGATGACAGCCATCCTCTACGGGCTGACCGCCTGA

Upstream 100 bases:

>100_bases
ACTATCCTTGCCGCGAATTTTGAGTCGCGACCCATACACCAGCGTCCATCACGACTCAGACCCCAACGTTTATCGCACCT
CTGGTGCCAAGGTTGAGCCC

Downstream 100 bases:

>100_bases
GTTGATTCAGGGGCGGCCCATGGCGTCGCCTCTGTATTTGGAGTCTTCCATGTTCAGTACCTTTGATATTTACAAGATTG
GTATCGGGCCTTCGAGCTCC

Product: amino acid transporter, transmembrane

Products: Proton [Cytoplasm]; D-serine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 438; Mature: 437

Protein sequence:

>438_residues
MSNETITAPATQASISSTVSQPHKATPNNAMPWTAQDTTWMLSLFGTAVGAGILFLPINAGMGGFWPLVVMALLIGPMTY
LAHRGLSRFVCSSSIAGSDITQVVEEHFGKGAGKAITVLYFFAIYPIVLIYGVGITNVVDSFMVNQLGLESLPRWLLSGV
LILGMMSVMVAGEKIMLKVTQFLVYPLVAILAFMSLYLMPNWNLAAVKEVPAVGDFLGTIWLTIPVLIFAFNHSPAISQF
AVSLKRDHGSNASRKADIILRNTAMMLVGFVMLFVFSCVLSLSPAQLAEAKSQNLPILSYLANVFDSGFVSYFGPFIAFV
AIVSSFFGHYMGASEGMSGIIKKQLEGKGKPVDEGKLNRFILGFMFLTIWAVAVINPSILGMIEALGGPIIAAILYLMPM
YAVYRVPALKAYRGRISNIFVIIAGLLSMTAILYGLTA

Sequences:

>Translated_438_residues
MSNETITAPATQASISSTVSQPHKATPNNAMPWTAQDTTWMLSLFGTAVGAGILFLPINAGMGGFWPLVVMALLIGPMTY
LAHRGLSRFVCSSSIAGSDITQVVEEHFGKGAGKAITVLYFFAIYPIVLIYGVGITNVVDSFMVNQLGLESLPRWLLSGV
LILGMMSVMVAGEKIMLKVTQFLVYPLVAILAFMSLYLMPNWNLAAVKEVPAVGDFLGTIWLTIPVLIFAFNHSPAISQF
AVSLKRDHGSNASRKADIILRNTAMMLVGFVMLFVFSCVLSLSPAQLAEAKSQNLPILSYLANVFDSGFVSYFGPFIAFV
AIVSSFFGHYMGASEGMSGIIKKQLEGKGKPVDEGKLNRFILGFMFLTIWAVAVINPSILGMIEALGGPIIAAILYLMPM
YAVYRVPALKAYRGRISNIFVIIAGLLSMTAILYGLTA
>Mature_437_residues
SNETITAPATQASISSTVSQPHKATPNNAMPWTAQDTTWMLSLFGTAVGAGILFLPINAGMGGFWPLVVMALLIGPMTYL
AHRGLSRFVCSSSIAGSDITQVVEEHFGKGAGKAITVLYFFAIYPIVLIYGVGITNVVDSFMVNQLGLESLPRWLLSGVL
ILGMMSVMVAGEKIMLKVTQFLVYPLVAILAFMSLYLMPNWNLAAVKEVPAVGDFLGTIWLTIPVLIFAFNHSPAISQFA
VSLKRDHGSNASRKADIILRNTAMMLVGFVMLFVFSCVLSLSPAQLAEAKSQNLPILSYLANVFDSGFVSYFGPFIAFVA
IVSSFFGHYMGASEGMSGIIKKQLEGKGKPVDEGKLNRFILGFMFLTIWAVAVINPSILGMIEALGGPIIAAILYLMPMY
AVYRVPALKAYRGRISNIFVIIAGLLSMTAILYGLTA

Specific function: Involved in the import of serine into the cell [H]

COG id: COG0814

COG function: function code E; Amino acid permeases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid/polyamine transporter 2 family. SdaC/TdcC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789160, Length=418, Percent_Identity=55.0239234449761, Blast_Score=450, Evalue=1e-127,
Organism=Escherichia coli, GI1789504, Length=426, Percent_Identity=44.6009389671362, Blast_Score=347, Evalue=9e-97,
Organism=Escherichia coli, GI1789211, Length=408, Percent_Identity=36.0294117647059, Blast_Score=252, Evalue=3e-68,
Organism=Escherichia coli, GI145693183, Length=439, Percent_Identity=26.6514806378132, Blast_Score=132, Evalue=5e-32,
Organism=Escherichia coli, GI1789961, Length=399, Percent_Identity=25.8145363408521, Blast_Score=132, Evalue=5e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004694
- InterPro:   IPR018227 [H]

Pfam domain/function: PF03222 Trp_Tyr_perm [H]

EC number: NA

Molecular weight: Translated: 47231; Mature: 47100

Theoretical pI: Translated: 9.47; Mature: 9.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
5.3 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
5.0 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNETITAPATQASISSTVSQPHKATPNNAMPWTAQDTTWMLSLFGTAVGAGILFLPINA
CCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCEEEEEECC
GMGGFWPLVVMALLIGPMTYLAHRGLSRFVCSSSIAGSDITQVVEEHFGKGAGKAITVLY
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCHHHHHHH
FFAIYPIVLIYGVGITNVVDSFMVNQLGLESLPRWLLSGVLILGMMSVMVAGEKIMLKVT
HHHHHHHHHHHHCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
QFLVYPLVAILAFMSLYLMPNWNLAAVKEVPAVGDFLGTIWLTIPVLIFAFNHSPAISQF
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
AVSLKRDHGSNASRKADIILRNTAMMLVGFVMLFVFSCVLSLSPAQLAEAKSQNLPILSY
HHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCHHHH
LANVFDSGFVSYFGPFIAFVAIVSSFFGHYMGASEGMSGIIKKQLEGKGKPVDEGKLNRF
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCHHCCHHHHHHHHHCCCCCCCCCHHHHHH
ILGFMFLTIWAVAVINPSILGMIEALGGPIIAAILYLMPMYAVYRVPALKAYRGRISNIF
HHHHHHHHHHHHHHHCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VIIAGLLSMTAILYGLTA
HHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SNETITAPATQASISSTVSQPHKATPNNAMPWTAQDTTWMLSLFGTAVGAGILFLPINA
CCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCEEEEEECC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HHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; D-serine [Periplasm] [C]

Specific reaction: Proton [Periplasm] + D-serine [Periplasm] = Proton [Cytoplasm] + D-serine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]