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The map label for this gene is ptxB [H]

Identifier: 119774680

GI number: 119774680

Start: 1879547

End: 1880401

Strand: Direct

Name: ptxB [H]

Synonym: Sama_1543

Alternate gene names: 119774680

Gene position: 1879547-1880401 (Clockwise)

Preceding gene: 119774677

Following gene: 119774681

Centisome position: 43.65

GC content: 53.33

Gene sequence:

>855_bases
ATGAAACTCCTGAGAAAATATTTAGCGCCGCTGCTGGTTGTACTTGCTCCTGCCGCTATGGCTGAAACCTTTACCTTTAC
AGCCATCCCTGACGAGGATGAAAGCCAGCTGCGTACCCGATTTGAAAAGGTTGCGGATTATCTCGAAACCAAGCTCGGTG
TTGAGGTCAAATATGTGCCGGTAAAATCCTACTCCGCAGCGGTCACAGCGTTTCGTAACAATCAGGTCCAATTGGCCTGG
TTTGGTGGTTTGTCCGGTGTGCAGGCCCGTCGTTTGGTGCCGGGCTCTGAGGCTATCGCACAGGGCTTTGAAGATCAGTT
CTTCAAGAGCTATTTTATTGCCCACCACAGCACAGGCCTTGAGCGCAGCGAAAACTTTCCGGCCATTGGTGGCTACACCT
TTACCTTCGGTTCCAAAGACTCCACCTCTGGCCGTTTGATGCCGCAGTTCTTCCTTGAGCGTAATTTGGGCAAACGTCCG
AAAGACCTGTTCAAACGTGTTGGCTTCTCGGGCGATCACAGCCGTACGGTGTCACAGGTTGAGGCTGGTGTATACCAGGT
GGGCGCAGTCAACTATAAGGTGTGGGATTCCATGGTAGAAGCCGGCAAGGTGGACACCAGCAAGGTGAAGGTGATTTGGG
AAAGCCCGGTTTACCCAGACTATCAGTGGACAGTGCGTGGCGACCTGAACAAACGTTTTGGCGACGGTTTTAAAGCCAGG
GTAACCCAGGCGCTGCTGGAGATGAAAGACCCCGATCTTCTGGCCTCCTTCCCCCGCCAGTCATTCGTCCCAGCTGACAA
TGAAGACTTCCAGCCGGTGGAAGACGTCGCCAAAGCCATTGGCCTGATTGACTGA

Upstream 100 bases:

>100_bases
ACGAATATTCTTAATCAACGCTGACCGGTAATCGCAACTGTTTTGTCTGTGCCTGCAGATACGTTACAATCTGCGCACTT
TGACTGCCCAGATACAGAAT

Downstream 100 bases:

>100_bases
TCATGCTGGTTCTTGACCGGCTTTCGCTGGACTACGGCGGCCGGGAGGTCATTAAAGACCTCTCGGTCGTTTTACATTCC
GGGCAAAAGGTTGCCCTTAT

Product: putative phosphonate ABC transporter periplasmic phosphonate-binding protein

Products: 3-phospho-serine [Cytoplasm]; phosphate [Cytoplasm]; alkylphosphonate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 284; Mature: 284

Protein sequence:

>284_residues
MKLLRKYLAPLLVVLAPAAMAETFTFTAIPDEDESQLRTRFEKVADYLETKLGVEVKYVPVKSYSAAVTAFRNNQVQLAW
FGGLSGVQARRLVPGSEAIAQGFEDQFFKSYFIAHHSTGLERSENFPAIGGYTFTFGSKDSTSGRLMPQFFLERNLGKRP
KDLFKRVGFSGDHSRTVSQVEAGVYQVGAVNYKVWDSMVEAGKVDTSKVKVIWESPVYPDYQWTVRGDLNKRFGDGFKAR
VTQALLEMKDPDLLASFPRQSFVPADNEDFQPVEDVAKAIGLID

Sequences:

>Translated_284_residues
MKLLRKYLAPLLVVLAPAAMAETFTFTAIPDEDESQLRTRFEKVADYLETKLGVEVKYVPVKSYSAAVTAFRNNQVQLAW
FGGLSGVQARRLVPGSEAIAQGFEDQFFKSYFIAHHSTGLERSENFPAIGGYTFTFGSKDSTSGRLMPQFFLERNLGKRP
KDLFKRVGFSGDHSRTVSQVEAGVYQVGAVNYKVWDSMVEAGKVDTSKVKVIWESPVYPDYQWTVRGDLNKRFGDGFKAR
VTQALLEMKDPDLLASFPRQSFVPADNEDFQPVEDVAKAIGLID
>Mature_284_residues
MKLLRKYLAPLLVVLAPAAMAETFTFTAIPDEDESQLRTRFEKVADYLETKLGVEVKYVPVKSYSAAVTAFRNNQVQLAW
FGGLSGVQARRLVPGSEAIAQGFEDQFFKSYFIAHHSTGLERSENFPAIGGYTFTFGSKDSTSGRLMPQFFLERNLGKRP
KDLFKRVGFSGDHSRTVSQVEAGVYQVGAVNYKVWDSMVEAGKVDTSKVKVIWESPVYPDYQWTVRGDLNKRFGDGFKAR
VTQALLEMKDPDLLASFPRQSFVPADNEDFQPVEDVAKAIGLID

Specific function: Probably forms part of a binding-protein-dependent phosphite transporter. Required for oxidation of phosphite to phosphate [H]

COG id: COG3221

COG function: function code P; ABC-type phosphate/phosphonate transport system, periplasmic component

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1790543, Length=215, Percent_Identity=24.6511627906977, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015168
- InterPro:   IPR005770 [H]

Pfam domain/function: PF09084 NMT1 [H]

EC number: NA

Molecular weight: Translated: 31793; Mature: 31793

Theoretical pI: Translated: 7.72; Mature: 7.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLLRKYLAPLLVVLAPAAMAETFTFTAIPDEDESQLRTRFEKVADYLETKLGVEVKYVP
CHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCEEEEEE
VKSYSAAVTAFRNNQVQLAWFGGLSGVQARRLVPGSEAIAQGFEDQFFKSYFIAHHSTGL
CCCCHHHHHEEECCEEEEEEECCCCCCCHHHCCCCHHHHHCCHHHHHHHHHHHHHCCCCC
ERSENFPAIGGYTFTFGSKDSTSGRLMPQFFLERNLGKRPKDLFKRVGFSGDHSRTVSQV
CCCCCCCCCCCEEEEECCCCCCCCCCHHHHHHHHCCCCCHHHHHHHCCCCCCCHHHHHHH
EAGVYQVGAVNYKVWDSMVEAGKVDTSKVKVIWESPVYPDYQWTVRGDLNKRFGDGFKAR
HHCHHHCCCCHHHHHHHHHHHCCCCCCEEEEEECCCCCCCEEEEEECCCCHHHCCCHHHH
VTQALLEMKDPDLLASFPRQSFVPADNEDFQPVEDVAKAIGLID
HHHHHHHCCCCHHHHHCCCCCCCCCCCCCCCHHHHHHHHHCCCC
>Mature Secondary Structure
MKLLRKYLAPLLVVLAPAAMAETFTFTAIPDEDESQLRTRFEKVADYLETKLGVEVKYVP
CHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCEEEEEE
VKSYSAAVTAFRNNQVQLAWFGGLSGVQARRLVPGSEAIAQGFEDQFFKSYFIAHHSTGL
CCCCHHHHHEEECCEEEEEEECCCCCCCHHHCCCCHHHHHCCHHHHHHHHHHHHHCCCCC
ERSENFPAIGGYTFTFGSKDSTSGRLMPQFFLERNLGKRPKDLFKRVGFSGDHSRTVSQV
CCCCCCCCCCCEEEEECCCCCCCCCCHHHHHHHHCCCCCHHHHHHHCCCCCCCHHHHHHH
EAGVYQVGAVNYKVWDSMVEAGKVDTSKVKVIWESPVYPDYQWTVRGDLNKRFGDGFKAR
HHCHHHCCCCHHHHHHHHHHHCCCCCCEEEEEECCCCCCCEEEEEECCCCHHHCCCHHHH
VTQALLEMKDPDLLASFPRQSFVPADNEDFQPVEDVAKAIGLID
HHHHHHHCCCCHHHHHCCCCCCCCCCCCCCCHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; 3-phospho-serine [Periplasm]; phosphite [Periplasm]; H2O; phosphate [Periplasm]; alkylphosphonate [Periplasm] [C]

Specific reaction: H2O + ATP + 3-phospho-serine [Periplasm] = ADP + phosphate + 3-phospho-serine [Cytoplasm] ATP + phosphite [Periplasm] + H2O = phosphite [Cytoplasm] + ADP + phosphate phosphate [Periplasm] + ATP + H2O = ADP + phosphate [Cytoplasm] + phosphate [Cytoplasm] A

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9791102 [H]