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The map label for this gene is gmhB [H]

Identifier: 119774672

GI number: 119774672

Start: 1866598

End: 1867152

Strand: Direct

Name: gmhB [H]

Synonym: Sama_1535

Alternate gene names: 119774672

Gene position: 1866598-1867152 (Clockwise)

Preceding gene: 119774670

Following gene: 119774673

Centisome position: 43.35

GC content: 48.65

Gene sequence:

>555_bases
GTGAAACGAGCAGTGTTTCTGGATAGGGATGGTGTCATCAATAAAGACCATGGTTATGTTCATACCGTGGATGACTTTGA
ATACATCGAAGGTGTATTCGAAGCCTGTCTCGCATTGAAAAACATGGGTTTTAAATTGGTGGTGGTAACCAATCAGTCAG
GCATTGCCCGTGGCATGTATACAGAAGACGATTTCCACAGCCTGACGGAATGGATGGACTGGAACTTTGCCGATAAAGGC
GTGGATCTCGACGGCATCTATTACTGCCCACACCATCCAGAAAAAGGTATTGGTGAATATAAGCAGGATTGTGATTGCCG
CAAACCCAAGCCCGGCATGCTGGAGTCAGCAGCCAAATTCCTGAAACTGGATCTGGCCAATTCGGTGATGGTGGGTGATA
AGGCTGATGATATGCGTGCGGCTGAAGCTGCAGGTATCCCGACTAAAATCCTGGTGAGAAGCGGTAAGCGGGTCGACTGC
GAAGGCGAAACGTTGGCAACAATCGTATTGGACAGTATCGCTGACGTACCGGCCTACCTGAAAGCACTCAAGTAA

Upstream 100 bases:

>100_bases
CAAAACAAGTGAAAAACATGCGTGCTGTCGCCAAGTTCGCGGTGCAATTCAAAAGCAGGAATGAAATAATAGCGCCACTT
GCAAAACCGGAGTCAAAGAA

Downstream 100 bases:

>100_bases
CAGTCGATGGTGAATCGCCCTTGCTCGGACGCAGAAGCCTGAATAGGGCTGAGTCACCATCGACATAGCCCCGCGGTTAT
ACCCCATGCCTTTTGAGACT

Product: D,D-heptose 1,7-bisphosphate phosphatase

Products: NA

Alternate protein names: D-glycero-D-manno-heptose 1,7-bisphosphate phosphatase [H]

Number of amino acids: Translated: 184; Mature: 184

Protein sequence:

>184_residues
MKRAVFLDRDGVINKDHGYVHTVDDFEYIEGVFEACLALKNMGFKLVVVTNQSGIARGMYTEDDFHSLTEWMDWNFADKG
VDLDGIYYCPHHPEKGIGEYKQDCDCRKPKPGMLESAAKFLKLDLANSVMVGDKADDMRAAEAAGIPTKILVRSGKRVDC
EGETLATIVLDSIADVPAYLKALK

Sequences:

>Translated_184_residues
MKRAVFLDRDGVINKDHGYVHTVDDFEYIEGVFEACLALKNMGFKLVVVTNQSGIARGMYTEDDFHSLTEWMDWNFADKG
VDLDGIYYCPHHPEKGIGEYKQDCDCRKPKPGMLESAAKFLKLDLANSVMVGDKADDMRAAEAAGIPTKILVRSGKRVDC
EGETLATIVLDSIADVPAYLKALK
>Mature_184_residues
MKRAVFLDRDGVINKDHGYVHTVDDFEYIEGVFEACLALKNMGFKLVVVTNQSGIARGMYTEDDFHSLTEWMDWNFADKG
VDLDGIYYCPHHPEKGIGEYKQDCDCRKPKPGMLESAAKFLKLDLANSVMVGDKADDMRAAEAAGIPTKILVRSGKRVDC
EGETLATIVLDSIADVPAYLKALK

Specific function: Converts the D-glycero-beta-D-manno-heptose 1,7- bisphosphate intermediate into D-glycero-beta-D-manno-heptose 1- phosphate by removing the phosphate group at the C-7 position [H]

COG id: COG0241

COG function: function code E; Histidinol phosphatase and related phosphatases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gmhB family [H]

Homologues:

Organism=Escherichia coli, GI1786399, Length=178, Percent_Identity=62.3595505617977, Blast_Score=241, Evalue=2e-65,
Organism=Escherichia coli, GI87082027, Length=148, Percent_Identity=34.4594594594595, Blast_Score=91, Evalue=3e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006549
- InterPro:   IPR004446
- InterPro:   IPR006543 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: 3.1.1.-

Molecular weight: Translated: 20456; Mature: 20456

Theoretical pI: Translated: 4.94; Mature: 4.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
6.5 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
6.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRAVFLDRDGVINKDHGYVHTVDDFEYIEGVFEACLALKNMGFKLVVVTNQSGIARGMY
CCCEEEECCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCC
TEDDFHSLTEWMDWNFADKGVDLDGIYYCPHHPEKGIGEYKQDCDCRKPKPGMLESAAKF
CCHHHHHHHHHHCCCCCCCCCCCCCEEECCCCCCCCCHHHHHCCCCCCCCCCHHHHHHHH
LKLDLANSVMVGDKADDMRAAEAAGIPTKILVRSGKRVDCEGETLATIVLDSIADVPAYL
HHHHHCCCEEECCCCHHHHHHHHCCCCCEEEECCCCEECCCCCHHHHHHHHHHHHHHHHH
KALK
HHCC
>Mature Secondary Structure
MKRAVFLDRDGVINKDHGYVHTVDDFEYIEGVFEACLALKNMGFKLVVVTNQSGIARGMY
CCCEEEECCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCC
TEDDFHSLTEWMDWNFADKGVDLDGIYYCPHHPEKGIGEYKQDCDCRKPKPGMLESAAKF
CCHHHHHHHHHHCCCCCCCCCCCCCEEECCCCCCCCCHHHHHCCCCCCCCCCHHHHHHHH
LKLDLANSVMVGDKADDMRAAEAAGIPTKILVRSGKRVDCEGETLATIVLDSIADVPAYL
HHHHHCCCEEECCCCHHHHHHHHCCCCCEEEECCCCEECCCCCHHHHHHHHHHHHHHHHH
KALK
HHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10952301; 12101286 [H]