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The map label for this gene is arsB [H]

Identifier: 119774615

GI number: 119774615

Start: 1789277

End: 1790353

Strand: Direct

Name: arsB [H]

Synonym: Sama_1478

Alternate gene names: 119774615

Gene position: 1789277-1790353 (Clockwise)

Preceding gene: 119774614

Following gene: 119774623

Centisome position: 41.55

GC content: 51.44

Gene sequence:

>1077_bases
ATGACGACCAATCGTTGTATTGATGTGCCTGTCAGCCAAAAGATGAGCTTTCTTGATCGCAATCTCACCCTGTGGATTTT
TGTTGCCATGGCGCTAGGGGTAGCACTCGGTTACCTGTTTCCCGGTATCGCCCAGCTCAATGAGTCGATGTCAGTGGGCT
CTACCAACGTGCCGCTGGCGATTGGCCTCATCCTGATGATGTATCCACCCTTGGCCAAGGTGAACTACGCCACCATGGGC
ACCATGGCAAGGGATCGCCGTGCCATTACCCTGTCGCTGCTGATGAACTGGTTGATTGGTCCGATACTGATGTTTGCCAT
CGCCCTGCTGTTTTTACGGGACTACCCGGGGTATATGGTCGGCCTGACCCTGATTGGCCTTGCCCGTTGCATCGCCATGG
TACTGGTATGGAATGATCTTGCCGGCGGCAGCAAGGAGTATGGCGCAGGACTGGTAGCCTTAAACAGCGCGTTTCAAATT
CTGACCTATAGCTTTATGGCGTGGCTGTTTATTACTGTCCTGCCGCCTCTGTTTGGACTGCAGGGGGTTGCTGTGGATAT
CACTATGCTGGATATTGCCAAAAGCGTGCTCATTTATCTCGGTATTCCCTTTGTCGCGGGTTTCTTAAGCCGTAAATACC
TGATTAGGGCCAAGGGCGAGCAGTGGTACACAGAACGCTTTATCCCGGCTATCTCGCCCATTACGCTGATAGCGCTATTG
GCAACCATAGTGCTGATGTTCAGCCTCAAGGGGGAAATGATAGTGCAGCTGCCAATGGATGTGCTGCGGGTCGCCCTTCC
TTTGGTGCTTTACTTTGTGCTGATGTTTTTCTCAAGCTTTTATATTGGTAAAAAGCTTGGGCTTCCCTACGATAAAAACG
CCTCTATCGCGTTTACTGCCACGGGAAATAACTTTGAGTTGGCTATAGCCGTTTCAATTGCGGTATTTGGCTTGAATTCA
GATCAGGCGTTTGCCGGTGTGATAGGTCCGCTGGTGGAGGTGCCTGTGCTTATCCTGCTGGTTAACGTGGCACTTCGCTT
CAAGCAAGGTTACACCAGGTCCTTAAGTGCGTCCTGA

Upstream 100 bases:

>100_bases
TTGGCCATATAAAGGTAAGCATTTTGGTGGTGGCCCCGATTTCAACTGGTTTACCATGTTATTGATATTATGAATTATCT
GAATTCTATGGAGTCTTTCG

Downstream 100 bases:

>100_bases
CGTCTATAGGGCTCAAGCCCAGGTTCTCAACGTCTGAGATGCAGTGACCAATATAATGTAATGGCGGAGTACCCGGGATT
TGGGTACTCCGCCAGATCGT

Product: arsenite efflux pump ACR3

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 358; Mature: 357

Protein sequence:

>358_residues
MTTNRCIDVPVSQKMSFLDRNLTLWIFVAMALGVALGYLFPGIAQLNESMSVGSTNVPLAIGLILMMYPPLAKVNYATMG
TMARDRRAITLSLLMNWLIGPILMFAIALLFLRDYPGYMVGLTLIGLARCIAMVLVWNDLAGGSKEYGAGLVALNSAFQI
LTYSFMAWLFITVLPPLFGLQGVAVDITMLDIAKSVLIYLGIPFVAGFLSRKYLIRAKGEQWYTERFIPAISPITLIALL
ATIVLMFSLKGEMIVQLPMDVLRVALPLVLYFVLMFFSSFYIGKKLGLPYDKNASIAFTATGNNFELAIAVSIAVFGLNS
DQAFAGVIGPLVEVPVLILLVNVALRFKQGYTRSLSAS

Sequences:

>Translated_358_residues
MTTNRCIDVPVSQKMSFLDRNLTLWIFVAMALGVALGYLFPGIAQLNESMSVGSTNVPLAIGLILMMYPPLAKVNYATMG
TMARDRRAITLSLLMNWLIGPILMFAIALLFLRDYPGYMVGLTLIGLARCIAMVLVWNDLAGGSKEYGAGLVALNSAFQI
LTYSFMAWLFITVLPPLFGLQGVAVDITMLDIAKSVLIYLGIPFVAGFLSRKYLIRAKGEQWYTERFIPAISPITLIALL
ATIVLMFSLKGEMIVQLPMDVLRVALPLVLYFVLMFFSSFYIGKKLGLPYDKNASIAFTATGNNFELAIAVSIAVFGLNS
DQAFAGVIGPLVEVPVLILLVNVALRFKQGYTRSLSAS
>Mature_357_residues
TTNRCIDVPVSQKMSFLDRNLTLWIFVAMALGVALGYLFPGIAQLNESMSVGSTNVPLAIGLILMMYPPLAKVNYATMGT
MARDRRAITLSLLMNWLIGPILMFAIALLFLRDYPGYMVGLTLIGLARCIAMVLVWNDLAGGSKEYGAGLVALNSAFQIL
TYSFMAWLFITVLPPLFGLQGVAVDITMLDIAKSVLIYLGIPFVAGFLSRKYLIRAKGEQWYTERFIPAISPITLIALLA
TIVLMFSLKGEMIVQLPMDVLRVALPLVLYFVLMFFSSFYIGKKLGLPYDKNASIAFTATGNNFELAIAVSIAVFGLNSD
QAFAGVIGPLVEVPVLILLVNVALRFKQGYTRSLSAS

Specific function: Seems to confer resistance to arsenite by allowing cells to extrude this compound. Could be part of an arsenite extrusion pump [H]

COG id: COG0798

COG function: function code P; Arsenite efflux pump ACR3 and related permeases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ACR3 family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6325459, Length=327, Percent_Identity=32.1100917431193, Blast_Score=155, Evalue=6e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004706
- InterPro:   IPR002657 [H]

Pfam domain/function: PF01758 SBF [H]

EC number: NA

Molecular weight: Translated: 39160; Mature: 39029

Theoretical pI: Translated: 9.63; Mature: 9.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
5.0 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTNRCIDVPVSQKMSFLDRNLTLWIFVAMALGVALGYLFPGIAQLNESMSVGSTNVPLA
CCCCCEECCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCCCHHH
IGLILMMYPPLAKVNYATMGTMARDRRAITLSLLMNWLIGPILMFAIALLFLRDYPGYMV
HHHHHHHCCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
GLTLIGLARCIAMVLVWNDLAGGSKEYGAGLVALNSAFQILTYSFMAWLFITVLPPLFGL
HHHHHHHHHHHHHHHHHHHCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
QGVAVDITMLDIAKSVLIYLGIPFVAGFLSRKYLIRAKGEQWYTERFIPAISPITLIALL
CCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCHHHHHHHCCCCCHHHHHHHH
ATIVLMFSLKGEMIVQLPMDVLRVALPLVLYFVLMFFSSFYIGKKLGLPYDKNASIAFTA
HHHHHHHHCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEE
TGNNFELAIAVSIAVFGLNSDQAFAGVIGPLVEVPVLILLVNVALRFKQGYTRSLSAS
ECCCEEEEEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
TTNRCIDVPVSQKMSFLDRNLTLWIFVAMALGVALGYLFPGIAQLNESMSVGSTNVPLA
CCCCEECCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCCCHHH
IGLILMMYPPLAKVNYATMGTMARDRRAITLSLLMNWLIGPILMFAIALLFLRDYPGYMV
HHHHHHHCCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
GLTLIGLARCIAMVLVWNDLAGGSKEYGAGLVALNSAFQILTYSFMAWLFITVLPPLFGL
HHHHHHHHHHHHHHHHHHHCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
QGVAVDITMLDIAKSVLIYLGIPFVAGFLSRKYLIRAKGEQWYTERFIPAISPITLIALL
CCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCHHHHHHHCCCCCHHHHHHHH
ATIVLMFSLKGEMIVQLPMDVLRVALPLVLYFVLMFFSSFYIGKKLGLPYDKNASIAFTA
HHHHHHHHCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEE
TGNNFELAIAVSIAVFGLNSDQAFAGVIGPLVEVPVLILLVNVALRFKQGYTRSLSAS
ECCCEEEEEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7704261; 8969508; 9384377; 7489895; 9537360 [H]