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The map label for this gene is crt [H]

Identifier: 119774515

GI number: 119774515

Start: 1669826

End: 1670599

Strand: Direct

Name: crt [H]

Synonym: Sama_1378

Alternate gene names: 119774515

Gene position: 1669826-1670599 (Clockwise)

Preceding gene: 119774514

Following gene: 119774516

Centisome position: 38.78

GC content: 57.62

Gene sequence:

>774_bases
ATGGCATTTTTGATTGAACGTATCGAAGGCAATACCGCCATCCTCACCATCAGCAATCCTCCGGCCAATACCTGGACCCG
TGAGAGCCTGAATGAGCTGAAGGAAAAGGTACTCGAGCTGAATGATAACAATGAGATTTACGCGCTGGTGTTGACCGGCG
AAGGGGAGAAGTTCTTTTCCGCGGGCGCTGATTTGAAACTCTTTGCCGACGGCGACAAGGGCAATGCCGCCACCATGGCC
AAGGCCTTCGGTGAAGCCTTTGAAACCTTGAGCGCCTTCCGTGGCGTGTCCATCGCGGCCATCAATGGCTATGCCATGGG
CGGAGGCCTCGAAGTGGCGCTGGCCTGTGATATCCGTATCGCCGAAATTCAGGCAGTAATGGCACTGCCCGAAGCCACAG
TGGGCCTCTTGCCCTGCGCCGGTGGTACCCAAAACCTGACTGCCCTGGTGGGCGAGGGCTGGGCCAAACGCATGATCCTC
TGTGGTGAGCGTATCGATGCCACCAAGGCGCTGAATCTTGGGCTGGTAGAAGAGGTGGTGGAGAAGGGCGAGTCCCTGAG
TGCCGCCATCGCCCTGGCCGCCAAGGTTGCCAAGCAAAGCCCATCTGCCGTGGCCGTGTGCAAAAAGCTTATTCAGAGTG
GGCGCAATATGCCACGCACCCAGGCACTGCCGCTGGAGCGTGAACTCTTTGTTGGTCTTTTTGATACCGAAGATCAAGCC
GAAGGGGTGAATGCCTTCCTCGAGAAGCGTGCCGCCCAGTGGAAAAACCGCTGA

Upstream 100 bases:

>100_bases
TCATTTCCCGTCGTCTGCTGGACGAAAACGCCAACGACATCCTCTGATTTGCCAGTGATTTCGATTGAATAGAGACTTCG
ACAGAAAAGGAATAACAGCC

Downstream 100 bases:

>100_bases
GGCCTTGCCTTGGACATGACATTACGCAAGGAGCGAGCATGACACAGAAAGTTGTATTTCAAACCCTGGGGACCGCCTCG
GGCAAGCAGATAGGTGTGGC

Product: enoyl-CoA hydratase

Products: NA

Alternate protein names: Crotonase [H]

Number of amino acids: Translated: 257; Mature: 256

Protein sequence:

>257_residues
MAFLIERIEGNTAILTISNPPANTWTRESLNELKEKVLELNDNNEIYALVLTGEGEKFFSAGADLKLFADGDKGNAATMA
KAFGEAFETLSAFRGVSIAAINGYAMGGGLEVALACDIRIAEIQAVMALPEATVGLLPCAGGTQNLTALVGEGWAKRMIL
CGERIDATKALNLGLVEEVVEKGESLSAAIALAAKVAKQSPSAVAVCKKLIQSGRNMPRTQALPLERELFVGLFDTEDQA
EGVNAFLEKRAAQWKNR

Sequences:

>Translated_257_residues
MAFLIERIEGNTAILTISNPPANTWTRESLNELKEKVLELNDNNEIYALVLTGEGEKFFSAGADLKLFADGDKGNAATMA
KAFGEAFETLSAFRGVSIAAINGYAMGGGLEVALACDIRIAEIQAVMALPEATVGLLPCAGGTQNLTALVGEGWAKRMIL
CGERIDATKALNLGLVEEVVEKGESLSAAIALAAKVAKQSPSAVAVCKKLIQSGRNMPRTQALPLERELFVGLFDTEDQA
EGVNAFLEKRAAQWKNR
>Mature_256_residues
AFLIERIEGNTAILTISNPPANTWTRESLNELKEKVLELNDNNEIYALVLTGEGEKFFSAGADLKLFADGDKGNAATMAK
AFGEAFETLSAFRGVSIAAINGYAMGGGLEVALACDIRIAEIQAVMALPEATVGLLPCAGGTQNLTALVGEGWAKRMILC
GERIDATKALNLGLVEEVVEKGESLSAAIALAAKVAKQSPSAVAVCKKLIQSGRNMPRTQALPLERELFVGLFDTEDQAE
GVNAFLEKRAAQWKNR

Specific function: Could Possibly Oxidizes Fatty Acids Using Specific Components (By Similarity). [C]

COG id: COG1024

COG function: function code I; Enoyl-CoA hydratase/carnithine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI194097323, Length=254, Percent_Identity=36.6141732283465, Blast_Score=142, Evalue=3e-34,
Organism=Homo sapiens, GI68989263, Length=211, Percent_Identity=37.4407582938389, Blast_Score=120, Evalue=2e-27,
Organism=Homo sapiens, GI20127408, Length=179, Percent_Identity=35.7541899441341, Blast_Score=97, Evalue=1e-20,
Organism=Homo sapiens, GI213417737, Length=236, Percent_Identity=29.6610169491525, Blast_Score=95, Evalue=5e-20,
Organism=Homo sapiens, GI157694516, Length=236, Percent_Identity=29.6610169491525, Blast_Score=95, Evalue=5e-20,
Organism=Homo sapiens, GI4502327, Length=237, Percent_Identity=31.6455696202532, Blast_Score=92, Evalue=4e-19,
Organism=Homo sapiens, GI157694520, Length=208, Percent_Identity=30.7692307692308, Blast_Score=89, Evalue=4e-18,
Organism=Homo sapiens, GI261878539, Length=113, Percent_Identity=46.0176991150442, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI31542718, Length=248, Percent_Identity=29.0322580645161, Blast_Score=86, Evalue=2e-17,
Organism=Homo sapiens, GI150378541, Length=250, Percent_Identity=30.8, Blast_Score=81, Evalue=8e-16,
Organism=Homo sapiens, GI62530384, Length=240, Percent_Identity=25, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI37594469, Length=183, Percent_Identity=24.5901639344262, Blast_Score=66, Evalue=3e-11,
Organism=Homo sapiens, GI37594471, Length=183, Percent_Identity=24.5901639344262, Blast_Score=66, Evalue=3e-11,
Organism=Homo sapiens, GI295842266, Length=184, Percent_Identity=27.7173913043478, Blast_Score=65, Evalue=6e-11,
Organism=Escherichia coli, GI1787659, Length=262, Percent_Identity=39.3129770992366, Blast_Score=155, Evalue=2e-39,
Organism=Escherichia coli, GI221142681, Length=252, Percent_Identity=34.9206349206349, Blast_Score=142, Evalue=3e-35,
Organism=Escherichia coli, GI1788682, Length=242, Percent_Identity=34.297520661157, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI87082183, Length=235, Percent_Identity=25.9574468085106, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI1788597, Length=249, Percent_Identity=24.4979919678715, Blast_Score=71, Evalue=5e-14,
Organism=Escherichia coli, GI1790281, Length=210, Percent_Identity=27.6190476190476, Blast_Score=71, Evalue=7e-14,
Organism=Escherichia coli, GI1787660, Length=262, Percent_Identity=29.0076335877863, Blast_Score=71, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI25145438, Length=245, Percent_Identity=37.9591836734694, Blast_Score=151, Evalue=3e-37,
Organism=Caenorhabditis elegans, GI17554946, Length=256, Percent_Identity=32.8125, Blast_Score=138, Evalue=3e-33,
Organism=Caenorhabditis elegans, GI17540714, Length=231, Percent_Identity=33.7662337662338, Blast_Score=117, Evalue=4e-27,
Organism=Caenorhabditis elegans, GI17558304, Length=183, Percent_Identity=32.2404371584699, Blast_Score=94, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17536985, Length=256, Percent_Identity=26.171875, Blast_Score=88, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI25144276, Length=192, Percent_Identity=33.8541666666667, Blast_Score=83, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17508953, Length=192, Percent_Identity=33.8541666666667, Blast_Score=83, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17508951, Length=192, Percent_Identity=33.8541666666667, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI25144157, Length=185, Percent_Identity=29.1891891891892, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI25144160, Length=185, Percent_Identity=29.1891891891892, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17540306, Length=259, Percent_Identity=26.2548262548263, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17534483, Length=189, Percent_Identity=26.984126984127, Blast_Score=74, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17560910, Length=165, Percent_Identity=30.3030303030303, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI20129971, Length=252, Percent_Identity=35.7142857142857, Blast_Score=137, Evalue=5e-33,
Organism=Drosophila melanogaster, GI24653477, Length=252, Percent_Identity=35.7142857142857, Blast_Score=137, Evalue=5e-33,
Organism=Drosophila melanogaster, GI24653139, Length=260, Percent_Identity=30.7692307692308, Blast_Score=112, Evalue=2e-25,
Organism=Drosophila melanogaster, GI24650670, Length=168, Percent_Identity=33.9285714285714, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24583165, Length=202, Percent_Identity=28.2178217821782, Blast_Score=71, Evalue=6e-13,
Organism=Drosophila melanogaster, GI19921018, Length=197, Percent_Identity=27.4111675126904, Blast_Score=71, Evalue=7e-13,
Organism=Drosophila melanogaster, GI19922422, Length=244, Percent_Identity=22.1311475409836, Blast_Score=71, Evalue=9e-13,
Organism=Drosophila melanogaster, GI45550169, Length=201, Percent_Identity=25.3731343283582, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI21357171, Length=150, Percent_Identity=31.3333333333333, Blast_Score=68, Evalue=7e-12,
Organism=Drosophila melanogaster, GI19920382, Length=201, Percent_Identity=28.3582089552239, Blast_Score=65, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014748
- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.55 [H]

Molecular weight: Translated: 27345; Mature: 27214

Theoretical pI: Translated: 4.63; Mature: 4.63

Prosite motif: PS00166 ENOYL_COA_HYDRATASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAFLIERIEGNTAILTISNPPANTWTRESLNELKEKVLELNDNNEIYALVLTGEGEKFFS
CCEEEEECCCCEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCHHHH
AGADLKLFADGDKGNAATMAKAFGEAFETLSAFRGVSIAAINGYAMGGGLEVALACDIRI
CCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEECCEEECCCEEEEEEECEEH
AEIQAVMALPEATVGLLPCAGGTQNLTALVGEGWAKRMILCGERIDATKALNLGLVEEVV
HHHHHHHHCCCCCEEEEECCCCCCCHHHHHCCCHHHHHHHCCCCCCHHHHHCHHHHHHHH
EKGESLSAAIALAAKVAKQSPSAVAVCKKLIQSGRNMPRTQALPLERELFVGLFDTEDQA
HCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCCCCHHHEEEEECCCCHH
EGVNAFLEKRAAQWKNR
HHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
AFLIERIEGNTAILTISNPPANTWTRESLNELKEKVLELNDNNEIYALVLTGEGEKFFS
CEEEEECCCCEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCHHHH
AGADLKLFADGDKGNAATMAKAFGEAFETLSAFRGVSIAAINGYAMGGGLEVALACDIRI
CCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEECCEEECCCEEEEEEECEEH
AEIQAVMALPEATVGLLPCAGGTQNLTALVGEGWAKRMILCGERIDATKALNLGLVEEVV
HHHHHHHHCCCCCEEEEECCCCCCCHHHHHCCCHHHHHHHCCCCCCHHHHHCHHHHHHHH
EKGESLSAAIALAAKVAKQSPSAVAVCKKLIQSGRNMPRTQALPLERELFVGLFDTEDQA
HCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCCCCHHHEEEEECCCCHH
EGVNAFLEKRAAQWKNR
HHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8655474; 11466286 [H]