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The map label for this gene is hscB

Identifier: 119774433

GI number: 119774433

Start: 1581877

End: 1582401

Strand: Direct

Name: hscB

Synonym: Sama_1296

Alternate gene names: 119774433

Gene position: 1581877-1582401 (Clockwise)

Preceding gene: 119774432

Following gene: 119774434

Centisome position: 36.74

GC content: 52.38

Gene sequence:

>525_bases
ATGAATTACTTCGAGCTGTTTAACCTTCCGGTTGCTTTCGATGTGAATACCAGTGAGCTCGCGGACAAATACCGCGAGCT
TCAGCGTACCGTACATCCCGATAAGTTTGCCGCCGCCAGTGAGCAGGAAAAACTGCTTGCGGTCAGTCGTACAGCCATGG
TGAACGACGGTTTCCAAACCCTCAAAGACCCCATTCGCCGCGCCGAGCATATGCTTGCGCTCAAAGGGGTTGATATTCGC
CATGAAACCCAAACCGTGCGCGATACTGCATTCCTGATGCAACAAATGGAATGGCGCGAGGCATTGGAAGAGATTACCCA
CGCAGACGATCCCCACTGCCTGATTGCTGACCTGTACCAGTCTTTCGGTGACTTCCAAAAGCAGGTGACTGCCAAGCTCA
AGACGTTGCTTGTCAGCGAAGACGACAATGACTTGCAAGCTGCGGCAGATCAGGTTCGCAAACTCAAGTTTATGGCAAAA
TTGCATGTGGAACTTGAGCGGGCGGAAGACGCACTGCTGGACTGA

Upstream 100 bases:

>100_bases
TTTCGTCAAGGAAGGCCTCAATGAGGGCTTCAAATTCAATAACCCCAATGCCAAGGGAGAATGCGGCTGCGGCGAGAGCT
TCACCGTATAATCCGGTTTT

Downstream 100 bases:

>100_bases
CACATTCCTTTTTAAGCCGGCGTCGGTCGCCGGCGTAAGTTAAGTTGGACACCTATGGCCTTATTGCAAATCGCCGAGCC
CGGCCAAAGCGCCGCGCCCC

Product: co-chaperone HscB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 174; Mature: 174

Protein sequence:

>174_residues
MNYFELFNLPVAFDVNTSELADKYRELQRTVHPDKFAAASEQEKLLAVSRTAMVNDGFQTLKDPIRRAEHMLALKGVDIR
HETQTVRDTAFLMQQMEWREALEEITHADDPHCLIADLYQSFGDFQKQVTAKLKTLLVSEDDNDLQAAADQVRKLKFMAK
LHVELERAEDALLD

Sequences:

>Translated_174_residues
MNYFELFNLPVAFDVNTSELADKYRELQRTVHPDKFAAASEQEKLLAVSRTAMVNDGFQTLKDPIRRAEHMLALKGVDIR
HETQTVRDTAFLMQQMEWREALEEITHADDPHCLIADLYQSFGDFQKQVTAKLKTLLVSEDDNDLQAAADQVRKLKFMAK
LHVELERAEDALLD
>Mature_174_residues
MNYFELFNLPVAFDVNTSELADKYRELQRTVHPDKFAAASEQEKLLAVSRTAMVNDGFQTLKDPIRRAEHMLALKGVDIR
HETQTVRDTAFLMQQMEWREALEEITHADDPHCLIADLYQSFGDFQKQVTAKLKTLLVSEDDNDLQAAADQVRKLKFMAK
LHVELERAEDALLD

Specific function: Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward hscA

COG id: COG1076

COG function: function code O; DnaJ-domain-containing proteins 1

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 J domain

Homologues:

Organism=Homo sapiens, GI50301234, Length=103, Percent_Identity=37.8640776699029, Blast_Score=75, Evalue=3e-14,
Organism=Escherichia coli, GI1788876, Length=175, Percent_Identity=45.1428571428571, Blast_Score=140, Evalue=4e-35,
Organism=Drosophila melanogaster, GI161084223, Length=173, Percent_Identity=26.0115606936416, Blast_Score=77, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HSCB_SHEAM (A1S547)

Other databases:

- EMBL:   CP000507
- RefSeq:   YP_927173.1
- ProteinModelPortal:   A1S547
- SMR:   A1S547
- STRING:   A1S547
- GeneID:   4603548
- GenomeReviews:   CP000507_GR
- KEGG:   saz:Sama_1296
- NMPDR:   fig|326297.7.peg.1223
- eggNOG:   COG1076
- HOGENOM:   HBG751004
- OMA:   NFFALFE
- PhylomeDB:   A1S547
- ProtClustDB:   PRK05014
- HAMAP:   MF_00682
- InterPro:   IPR001623
- InterPro:   IPR009073
- InterPro:   IPR004640
- Gene3D:   G3DSA:1.10.287.110
- Gene3D:   G3DSA:1.20.1280.20
- SMART:   SM00271
- TIGRFAMs:   TIGR00714

Pfam domain/function: PF00226 DnaJ; PF07743 HSCB_C; SSF46565 DnaJ_N; SSF47144 HSC20_C

EC number: NA

Molecular weight: Translated: 20037; Mature: 20037

Theoretical pI: Translated: 4.73; Mature: 4.73

Prosite motif: PS00636 DNAJ_1; PS50076 DNAJ_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNYFELFNLPVAFDVNTSELADKYRELQRTVHPDKFAAASEQEKLLAVSRTAMVNDGFQT
CCHHHHCCCCEEEECCHHHHHHHHHHHHHHCCCHHHHHCCHHHHHHHHHHHHHHHCCHHH
LKDPIRRAEHMLALKGVDIRHETQTVRDTAFLMQQMEWREALEEITHADDPHCLIADLYQ
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
SFGDFQKQVTAKLKTLLVSEDDNDLQAAADQVRKLKFMAKLHVELERAEDALLD
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNYFELFNLPVAFDVNTSELADKYRELQRTVHPDKFAAASEQEKLLAVSRTAMVNDGFQT
CCHHHHCCCCEEEECCHHHHHHHHHHHHHHCCCHHHHHCCHHHHHHHHHHHHHHHCCHHH
LKDPIRRAEHMLALKGVDIRHETQTVRDTAFLMQQMEWREALEEITHADDPHCLIADLYQ
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
SFGDFQKQVTAKLKTLLVSEDDNDLQAAADQVRKLKFMAKLHVELERAEDALLD
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA