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The map label for this gene is gltB [H]

Identifier: 119773994

GI number: 119773994

Start: 1043376

End: 1047827

Strand: Reverse

Name: gltB [H]

Synonym: Sama_0857

Alternate gene names: 119773994

Gene position: 1047827-1043376 (Counterclockwise)

Preceding gene: 119773998

Following gene: 119773993

Centisome position: 24.33

GC content: 57.52

Gene sequence:

>4452_bases
ATGAGCTTGTATCATCCCAGTTTTGAGCGGGACAATTGTGGATTTGGTCTGATTGCCCAGATGGACGGCGAAGCCAGTCA
CCGTATTGTGCGTACCGCCATTACCGGACTGGATCGCATGAAGCACCGCGGCGGCATTGCCGCAGATGGTCGCACGGGTG
ATGGTTGCGGCCTCCTGATGCAATTGCCCATCAAGTTTTTCGAGTCGATTGCCGCCGAAAATGACTGGCACCTGTCGCGC
AAGTTTGCCGTCGGCATGTTCTTTTTAAGTCAGGACGAAGAAAAAGTCGCTGCCGCACGCTTTGTGCTTGAGCGCGAGCT
TGAAAAAGAAACCCTCTGCATCGCCGGTTGGCGTGAGGTGCCTGTTAATCCCGATGTGCTGGGTGAAATAGGTAAGGCCA
GCCTGCCACGTATCGTTCAGGTACTGATTAATGCGCCCATTGGCTGGCGTGAAAAAGACCTCGAACGTCGCCTCTATATG
GCCCGTCGCCGCCTCGAGCAGCAAATGACTGCCGATCCCGACTTCTATGTGGCCAGTCTTTCTGGTCAGGTGATTGTTTA
TAAAGGCCTGATGATGCCAGCGGACCTGCCCGCCTTTTATCCCGATCTGGCCGATTTGCGTCTGGAAAGTGCTATCTGTT
TGTTCCACCAGCGCTTTTCAACCAATACTTCTCCCAAGTGGCCACTGGCTCAGCCTTTCCGCTATCTGGCGCACAACGGT
GAAATCAACACCATTACCGGCAACCGCCAGTGGGCCCGCGCCCGCGCGTACAAGTTCAATTCGCCGCTGTTGCCCGATTT
GCAGCAAGCCGCCCCCTTTGTAAACGAAACCGGCTCTGACTCATCCTCTTTGGATAACATGCTGGAAATGCTGCTCTCCG
GCGGAATGGACCTGTACCGTGCCATGCGTTTGCTGATTCCGCCCGCATGGCAAAGTAACCCTGAAATGGACGAAGAGCTC
AAAGCCTTCTACGACTTTAACTCCATGCATATGGAACCCTGGGATGGACCGGCGGGTATAGTCATGACCAACGGCCGCCA
CGCCGCCTGCGCGGTGGACCGTAACGGCCTGCGTCCATCCCGTTATGTGATTACCAAGGACCGCATACTGACCCTGGCCT
CTGAAGTGGGTATCTGGGATTACCAGCCCGACGAGGTGGTGGAAAAGGGGCGCGTTGGTCCGGGTGAGCTTTTGGTGCTC
GATACCCTAAACGGTCGCCTGTATCAGTCATTCGAGATTGATAACGACCTCAAACGCCGTCATCCCTATAAAGAATGGAT
GGCGAAGAACAGCCGCACCCTCAAGAGTGCGGAAGAGATGAGTAGCGAGCAGCACGGCGCCAGCGAATTCAGTCGTGATA
CCCTGCTACAGTACCAAAAGCTGTTTGGCTACAGCCGTGAAGAACTCGAACAGGTTATTTGGGTACTGGCAAGCCAGGGT
GAAGAGGCCGTGGGCTCCATGGGCGACGATACCCCCATGGCGGTGCTGTCCAACAAACAGCGCTCACTTTACGACTACTT
CCGCCAGAAATTCGCCCAGGTGACAAACCCGCCCATCGACCCACTGCGTGAAAAACACGTGATGTCGCTGGCCACCTGTG
TGGGCCGTGAGCAGAACCTCTTCAATGAAACCACAGGCCACGCCTACCGGGTGATGTTCAACTCGCCTGTTTTGCTGTTC
AGCGATTTCAATCAGTTGATGTCCCTCGATAAAGCCTATTACCGCGCCAATATCGTTGACCTCAACTACGACCCGGCAGA
AGGGCTTGAAGGCGCCATTCGCCGCATCACAGATGATGCCGAGCGTCTGGCCCGCACCGGCACTACGCTGCTGGTGCTGT
CTGACCGCGCCGTGGCCAAAAACCGTCAGGTGATCCCGGCCGCCATGGCTGTGGGCGCCGTGCAGCAGATGCTGGTATCC
AAGAGCCTGCGCTGCGACACCAACATTATCGTGGAAACCGCCTCTGCCCGCGATCCACACCACTTTGCGGTGTTGCTGGG
CTTTGGTGCCACCGCCATCTATCCCTACCTGGTGTATGAATCCATTGCCGACCTGGCCAAGCGCAATGACAGCGCCGACG
ACATGGTGGCCTTGATGCTGAACTTCCGTTACGGCATCGAGAAAGGACTGCGCAAGATCATGTCCAAGATGGGTATCAGC
ACAGTGGCTTCATACCGCTGCAGCCAGCAGTTCGAGGCCATAGGTCTGGCCCGCGATGTCATTGAACTCTGCTTTAAAGG
CGTGGTGAGTCGCATCGAAGGGGTGAGCTTTGATCACCTTGCCAAGGACCAGCATAAGCTGCATCAGGCCGCCTTCCGCC
CCCACGTTTCCTTGCAACAGGGCGGTTTGCTCAAGTACGTCGAAGGCGGTGAGTACCATGCCTTCAACCCTGATGTGGTC
AATACGCTGCAGGCTTCACTCATCAGTCGCGACTACAGCAAGTACAAGGCCTTTGCCAAGCACGTCGATGAGCGTCCGGT
GGCAATGCTCCGGGATCTGTTGGGCGTAAAAGGCACCCTCGATGCCATTCCCGCCGACACGGTAGAAGCCGCAGCCAACC
TGTATCCCCGCTTCGACAGCGCCGCCATGAGTATCGGTGCCTTAAGCCCCGAAGCCCACGAAGCGCTGGCCATTGCCATG
AACCGCCTCGGCGGCCGTTCCAACTCAGGGGAAGGCGGCGAAGACCCGCGCCGTTTCGGTACCGAGAAGAACTCCGCCAT
CAAGCAAATTGCCTCTGGCCGTTTTGGTGTCACCGCCCATTACCTTATCAATGCCGAAGTGCTGCAGATTAAAGTGGCTC
AGGGGGCTAAACCCGGCGAAGGCGGTCAGCTGCCCGGCCACAAGGTGAGCGTGGAAATTGCCGGTCTGCGTTATGCCCGT
CCGGGCGTGACCCTGATTTCGCCACCGCCGCACCACGACATCTATTCCATTGAAGATTTGGCGCAGCTGATTTTCGATTT
GAAGCAAATCAACCCCAAGGCCCTTATCAGCGTAAAACTGGTATCAGAGCCGGGCATTGGCACCATCGCCACGGGTGTTG
CCAAGGCCTATGCCGACATGATTACCGTGTCCGGCTATGACGGTGGCACCGGGGCAAGCCCCCTCACCTCGGTCAAGTAT
GCCGGCTCGCCTTGGGAGCTGGGTCTGGCAGAGGTGCATCAGGCTCTGGTGGACAACGGCCTGCGCCACAAAATCCGCCT
GCAGGTGGACGGCGGCCTCAAAACAGGTACCGACGTTATCAAGGCCGCATTGCTTGGCGCCGAGAGTTTTGGCTTCGGCA
CAGTGCCTATGATTGCGCTGGGCTGTAAATATCTGAGAATCTGCCACCTGAACAACTGCGCCACCGGCGTGGCAACCCAG
GATAAAAATCTGCGCGATAAACACTTCCACGGCTTGCCTGAGCGGGTGATGACTTACTTCGAATTTGTTGCCGAAGAAGT
CCGTGAGTGGATGGCCAGGCTGGGTGTTGCAAAGTTTGAAGATCTGGTAGGTCGCAGCGACTGGTTGTACGCACTGGCGG
GACAAACCGAGAAGCAACATGGTCTGGATCTGTCCCCCATCCTGTATCAGCCACAGGTACGCGCTGGGTCATCCAGAACC
TGGAAAGAGATAAACCCACCGACGGATACCGGTGAGCTGAACCAGCGTCTGCTGAAAGATGCCGCCGATGCCATCAGCCG
CGGCGAAGGTTTCAGCGCCGCCTACAGCATCAACAACACAGATCGCTCAGTGGGCGCCGCCCTCAGTGGCCACATCGCTG
CCTGCTGTGGTCTCAAGGGCACCAAGGCGCCGGTCAGCCTGTCATTTAACGGCACCGCCGGCCAAAGTTTTGGTGTGTGG
AACGCCCCCGGACTGGAAATGAGCCTGTGCGGTGATGCCAACGACTATGTGGGCAAGGGGATGTCCGGCGGCAAGCTGTC
CATCTACCCGCCACTTGGCAGTGCCTTCCAGAGCGAGCGCACCGCCATCGTGGGCAATACCTGCCTCTATGGCGCAACCG
GCGGCCAGTTCTTTGCTGCGGGCCAGGCGGGTGAACGCTTCGGTGTGCGCAACTCAGGCGCCGTGGCGGTGGTAGAAGGC
CTTGGCGACAACGGCTGCGAATATATGACCGGCGGCATTGTGGTGGTATTGGGTAAAACCGGGGTGAACTTTGGCGCCGG
TATGACAGGTGGCTTTGCCTACGTGTTCGACCAGTTCGGCCGCTTTGGCCGCAGGGTAAACACCGAAATGGTCGACACCC
AAAAGGTGGAGTCAGCCATTCACCAGAAACACCTCAAAGGCCTGATAGAGGCCCACGTCAAAGAGACCGGCAGCGAACAT
GCCCGGGCGATTTTGAGTGACTTTGATAACTGGCTCGACTGCTTCGTGCTGGTCAAGCCGAAGAATGTAGCGGTGGCCGA
TCTGCTCAAACTCGAGCAGCCAAGCCCTGAACTGGCAGTAAAGGCGGGGTAA

Upstream 100 bases:

>100_bases
TTCTCAGGATAATTTGGGAGATTCGGGTGCATATCTATCATTGTCATTTGCGTGATTCCCCGAGCAGTATCAGTCACAGG
TTTTCAGGTGGGGAATTAGT

Downstream 100 bases:

>100_bases
CAGCAAGATGAGTAACGACTTTCAGTTTATTCAGGTAGGCCGCAAAGATCCGACCAAGCAGCCCATTAAGCTGCGTGCAA
CACAGTTTATTGAAATTTAT

Product: glutamate synthase subunit alpha

Products: NA

Alternate protein names: Glutamate synthase subunit alpha; GLTS alpha chain; NADPH-GOGAT [H]

Number of amino acids: Translated: 1483; Mature: 1482

Protein sequence:

>1483_residues
MSLYHPSFERDNCGFGLIAQMDGEASHRIVRTAITGLDRMKHRGGIAADGRTGDGCGLLMQLPIKFFESIAAENDWHLSR
KFAVGMFFLSQDEEKVAAARFVLERELEKETLCIAGWREVPVNPDVLGEIGKASLPRIVQVLINAPIGWREKDLERRLYM
ARRRLEQQMTADPDFYVASLSGQVIVYKGLMMPADLPAFYPDLADLRLESAICLFHQRFSTNTSPKWPLAQPFRYLAHNG
EINTITGNRQWARARAYKFNSPLLPDLQQAAPFVNETGSDSSSLDNMLEMLLSGGMDLYRAMRLLIPPAWQSNPEMDEEL
KAFYDFNSMHMEPWDGPAGIVMTNGRHAACAVDRNGLRPSRYVITKDRILTLASEVGIWDYQPDEVVEKGRVGPGELLVL
DTLNGRLYQSFEIDNDLKRRHPYKEWMAKNSRTLKSAEEMSSEQHGASEFSRDTLLQYQKLFGYSREELEQVIWVLASQG
EEAVGSMGDDTPMAVLSNKQRSLYDYFRQKFAQVTNPPIDPLREKHVMSLATCVGREQNLFNETTGHAYRVMFNSPVLLF
SDFNQLMSLDKAYYRANIVDLNYDPAEGLEGAIRRITDDAERLARTGTTLLVLSDRAVAKNRQVIPAAMAVGAVQQMLVS
KSLRCDTNIIVETASARDPHHFAVLLGFGATAIYPYLVYESIADLAKRNDSADDMVALMLNFRYGIEKGLRKIMSKMGIS
TVASYRCSQQFEAIGLARDVIELCFKGVVSRIEGVSFDHLAKDQHKLHQAAFRPHVSLQQGGLLKYVEGGEYHAFNPDVV
NTLQASLISRDYSKYKAFAKHVDERPVAMLRDLLGVKGTLDAIPADTVEAAANLYPRFDSAAMSIGALSPEAHEALAIAM
NRLGGRSNSGEGGEDPRRFGTEKNSAIKQIASGRFGVTAHYLINAEVLQIKVAQGAKPGEGGQLPGHKVSVEIAGLRYAR
PGVTLISPPPHHDIYSIEDLAQLIFDLKQINPKALISVKLVSEPGIGTIATGVAKAYADMITVSGYDGGTGASPLTSVKY
AGSPWELGLAEVHQALVDNGLRHKIRLQVDGGLKTGTDVIKAALLGAESFGFGTVPMIALGCKYLRICHLNNCATGVATQ
DKNLRDKHFHGLPERVMTYFEFVAEEVREWMARLGVAKFEDLVGRSDWLYALAGQTEKQHGLDLSPILYQPQVRAGSSRT
WKEINPPTDTGELNQRLLKDAADAISRGEGFSAAYSINNTDRSVGAALSGHIAACCGLKGTKAPVSLSFNGTAGQSFGVW
NAPGLEMSLCGDANDYVGKGMSGGKLSIYPPLGSAFQSERTAIVGNTCLYGATGGQFFAAGQAGERFGVRNSGAVAVVEG
LGDNGCEYMTGGIVVVLGKTGVNFGAGMTGGFAYVFDQFGRFGRRVNTEMVDTQKVESAIHQKHLKGLIEAHVKETGSEH
ARAILSDFDNWLDCFVLVKPKNVAVADLLKLEQPSPELAVKAG

Sequences:

>Translated_1483_residues
MSLYHPSFERDNCGFGLIAQMDGEASHRIVRTAITGLDRMKHRGGIAADGRTGDGCGLLMQLPIKFFESIAAENDWHLSR
KFAVGMFFLSQDEEKVAAARFVLERELEKETLCIAGWREVPVNPDVLGEIGKASLPRIVQVLINAPIGWREKDLERRLYM
ARRRLEQQMTADPDFYVASLSGQVIVYKGLMMPADLPAFYPDLADLRLESAICLFHQRFSTNTSPKWPLAQPFRYLAHNG
EINTITGNRQWARARAYKFNSPLLPDLQQAAPFVNETGSDSSSLDNMLEMLLSGGMDLYRAMRLLIPPAWQSNPEMDEEL
KAFYDFNSMHMEPWDGPAGIVMTNGRHAACAVDRNGLRPSRYVITKDRILTLASEVGIWDYQPDEVVEKGRVGPGELLVL
DTLNGRLYQSFEIDNDLKRRHPYKEWMAKNSRTLKSAEEMSSEQHGASEFSRDTLLQYQKLFGYSREELEQVIWVLASQG
EEAVGSMGDDTPMAVLSNKQRSLYDYFRQKFAQVTNPPIDPLREKHVMSLATCVGREQNLFNETTGHAYRVMFNSPVLLF
SDFNQLMSLDKAYYRANIVDLNYDPAEGLEGAIRRITDDAERLARTGTTLLVLSDRAVAKNRQVIPAAMAVGAVQQMLVS
KSLRCDTNIIVETASARDPHHFAVLLGFGATAIYPYLVYESIADLAKRNDSADDMVALMLNFRYGIEKGLRKIMSKMGIS
TVASYRCSQQFEAIGLARDVIELCFKGVVSRIEGVSFDHLAKDQHKLHQAAFRPHVSLQQGGLLKYVEGGEYHAFNPDVV
NTLQASLISRDYSKYKAFAKHVDERPVAMLRDLLGVKGTLDAIPADTVEAAANLYPRFDSAAMSIGALSPEAHEALAIAM
NRLGGRSNSGEGGEDPRRFGTEKNSAIKQIASGRFGVTAHYLINAEVLQIKVAQGAKPGEGGQLPGHKVSVEIAGLRYAR
PGVTLISPPPHHDIYSIEDLAQLIFDLKQINPKALISVKLVSEPGIGTIATGVAKAYADMITVSGYDGGTGASPLTSVKY
AGSPWELGLAEVHQALVDNGLRHKIRLQVDGGLKTGTDVIKAALLGAESFGFGTVPMIALGCKYLRICHLNNCATGVATQ
DKNLRDKHFHGLPERVMTYFEFVAEEVREWMARLGVAKFEDLVGRSDWLYALAGQTEKQHGLDLSPILYQPQVRAGSSRT
WKEINPPTDTGELNQRLLKDAADAISRGEGFSAAYSINNTDRSVGAALSGHIAACCGLKGTKAPVSLSFNGTAGQSFGVW
NAPGLEMSLCGDANDYVGKGMSGGKLSIYPPLGSAFQSERTAIVGNTCLYGATGGQFFAAGQAGERFGVRNSGAVAVVEG
LGDNGCEYMTGGIVVVLGKTGVNFGAGMTGGFAYVFDQFGRFGRRVNTEMVDTQKVESAIHQKHLKGLIEAHVKETGSEH
ARAILSDFDNWLDCFVLVKPKNVAVADLLKLEQPSPELAVKAG
>Mature_1482_residues
SLYHPSFERDNCGFGLIAQMDGEASHRIVRTAITGLDRMKHRGGIAADGRTGDGCGLLMQLPIKFFESIAAENDWHLSRK
FAVGMFFLSQDEEKVAAARFVLERELEKETLCIAGWREVPVNPDVLGEIGKASLPRIVQVLINAPIGWREKDLERRLYMA
RRRLEQQMTADPDFYVASLSGQVIVYKGLMMPADLPAFYPDLADLRLESAICLFHQRFSTNTSPKWPLAQPFRYLAHNGE
INTITGNRQWARARAYKFNSPLLPDLQQAAPFVNETGSDSSSLDNMLEMLLSGGMDLYRAMRLLIPPAWQSNPEMDEELK
AFYDFNSMHMEPWDGPAGIVMTNGRHAACAVDRNGLRPSRYVITKDRILTLASEVGIWDYQPDEVVEKGRVGPGELLVLD
TLNGRLYQSFEIDNDLKRRHPYKEWMAKNSRTLKSAEEMSSEQHGASEFSRDTLLQYQKLFGYSREELEQVIWVLASQGE
EAVGSMGDDTPMAVLSNKQRSLYDYFRQKFAQVTNPPIDPLREKHVMSLATCVGREQNLFNETTGHAYRVMFNSPVLLFS
DFNQLMSLDKAYYRANIVDLNYDPAEGLEGAIRRITDDAERLARTGTTLLVLSDRAVAKNRQVIPAAMAVGAVQQMLVSK
SLRCDTNIIVETASARDPHHFAVLLGFGATAIYPYLVYESIADLAKRNDSADDMVALMLNFRYGIEKGLRKIMSKMGIST
VASYRCSQQFEAIGLARDVIELCFKGVVSRIEGVSFDHLAKDQHKLHQAAFRPHVSLQQGGLLKYVEGGEYHAFNPDVVN
TLQASLISRDYSKYKAFAKHVDERPVAMLRDLLGVKGTLDAIPADTVEAAANLYPRFDSAAMSIGALSPEAHEALAIAMN
RLGGRSNSGEGGEDPRRFGTEKNSAIKQIASGRFGVTAHYLINAEVLQIKVAQGAKPGEGGQLPGHKVSVEIAGLRYARP
GVTLISPPPHHDIYSIEDLAQLIFDLKQINPKALISVKLVSEPGIGTIATGVAKAYADMITVSGYDGGTGASPLTSVKYA
GSPWELGLAEVHQALVDNGLRHKIRLQVDGGLKTGTDVIKAALLGAESFGFGTVPMIALGCKYLRICHLNNCATGVATQD
KNLRDKHFHGLPERVMTYFEFVAEEVREWMARLGVAKFEDLVGRSDWLYALAGQTEKQHGLDLSPILYQPQVRAGSSRTW
KEINPPTDTGELNQRLLKDAADAISRGEGFSAAYSINNTDRSVGAALSGHIAACCGLKGTKAPVSLSFNGTAGQSFGVWN
APGLEMSLCGDANDYVGKGMSGGKLSIYPPLGSAFQSERTAIVGNTCLYGATGGQFFAAGQAGERFGVRNSGAVAVVEGL
GDNGCEYMTGGIVVVLGKTGVNFGAGMTGGFAYVFDQFGRFGRRVNTEMVDTQKVESAIHQKHLKGLIEAHVKETGSEHA
RAILSDFDNWLDCFVLVKPKNVAVADLLKLEQPSPELAVKAG

Specific function: NITROGEN METABOLISM, GLUTAMATE BIOSYNTHESIS. THE CATALYZED REACTION BRINGS TOGETHER THE NITROGEN AND CARBON METABOLISM. [C]

COG id: COG0069

COG function: function code E; Glutamate synthase domain 2

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-2 domain [H]

Homologues:

Organism=Escherichia coli, GI308199519, Length=1484, Percent_Identity=66.3746630727763, Blast_Score=2022, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17570289, Length=1537, Percent_Identity=42.615484710475, Blast_Score=1094, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6320030, Length=1519, Percent_Identity=42.4621461487821, Blast_Score=1147, Evalue=0.0,
Organism=Drosophila melanogaster, GI28574881, Length=1520, Percent_Identity=42.7631578947368, Blast_Score=1123, Evalue=0.0,
Organism=Drosophila melanogaster, GI24665539, Length=1520, Percent_Identity=42.7631578947368, Blast_Score=1123, Evalue=0.0,
Organism=Drosophila melanogaster, GI24665547, Length=392, Percent_Identity=42.3469387755102, Blast_Score=271, Evalue=3e-72,
Organism=Drosophila melanogaster, GI24665543, Length=392, Percent_Identity=42.3469387755102, Blast_Score=271, Evalue=3e-72,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR000583
- InterPro:   IPR017932
- InterPro:   IPR002932
- InterPro:   IPR006982
- InterPro:   IPR002489 [H]

Pfam domain/function: PF00310 GATase_2; PF04898 Glu_syn_central; PF01645 Glu_synthase; PF01493 GXGXG [H]

EC number: =1.4.1.13 [H]

Molecular weight: Translated: 162553; Mature: 162422

Theoretical pI: Translated: 6.70; Mature: 6.70

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLYHPSFERDNCGFGLIAQMDGEASHRIVRTAITGLDRMKHRGGIAADGRTGDGCGLLM
CCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHH
QLPIKFFESIAAENDWHLSRKFAVGMFFLSQDEEKVAAARFVLERELEKETLCIAGWREV
HHHHHHHHHHHCCCCCCHHHHHHHEEEEECCCHHHHHHHHHHHHHHHHHHHEEEECCCCC
PVNPDVLGEIGKASLPRIVQVLINAPIGWREKDLERRLYMARRRLEQQMTADPDFYVASL
CCCHHHHHHCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEC
SGQVIVYKGLMMPADLPAFYPDLADLRLESAICLFHQRFSTNTSPKWPLAQPFRYLAHNG
CCCEEEEECCCCCCCCCHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCC
EINTITGNRQWARARAYKFNSPLLPDLQQAAPFVNETGSDSSSLDNMLEMLLSGGMDLYR
CEEEEECCCHHHHHHHEECCCCCCCCHHHHCCCCCCCCCCHHHHHHHHHHHHHCCHHHHH
AMRLLIPPAWQSNPEMDEELKAFYDFNSMHMEPWDGPAGIVMTNGRHAACAVDRNGLRPS
HHHHHCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCEEEECCCEEEEEECCCCCCCC
RYVITKDRILTLASEVGIWDYQPDEVVEKGRVGPGELLVLDTLNGRLYQSFEIDNDLKRR
EEEEEHHHHHHHHHHCCCCCCCHHHHHHCCCCCCCCEEEEEECCCCEEEEECCCCHHHHC
HPYKEWMAKNSRTLKSAEEMSSEQHGASEFSRDTLLQYQKLFGYSREELEQVIWVLASQG
CCHHHHHHCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCC
EEAVGSMGDDTPMAVLSNKQRSLYDYFRQKFAQVTNPPIDPLREKHVMSLATCVGREQNL
CHHHHCCCCCCCHHHHCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCHHHH
FNETTGHAYRVMFNSPVLLFSDFNQLMSLDKAYYRANIVDLNYDPAEGLEGAIRRITDDA
HHCCCCCEEEEEECCCEEEEHHHHHHHHHHHHHHEEEEEEECCCCHHHHHHHHHHHHHHH
ERLARTGTTLLVLSDRAVAKNRQVIPAAMAVGAVQQMLVSKSLRCDTNIIVETASARDPH
HHHHHCCCEEEEEECCHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCC
HFAVLLGFGATAIYPYLVYESIADLAKRNDSADDMVALMLNFRYGIEKGLRKIMSKMGIS
EEEEEEECCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCHH
TVASYRCSQQFEAIGLARDVIELCFKGVVSRIEGVSFDHLAKDQHKLHQAAFRPHVSLQQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCC
GGLLKYVEGGEYHAFNPDVVNTLQASLISRDYSKYKAFAKHVDERPVAMLRDLLGVKGTL
CCEEEEEECCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCC
DAIPADTVEAAANLYPRFDSAAMSIGALSPEAHEALAIAMNRLGGRSNSGEGGEDPRRFG
CCCCCHHHHHHHHHCCCCCHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHCC
TEKNSAIKQIASGRFGVTAHYLINAEVLQIKVAQGAKPGEGGQLPGHKVSVEIAGLRYAR
CCHHHHHHHHHCCCCCEEEEEEEECEEEEEEEECCCCCCCCCCCCCCEEEEEEECEEECC
PGVTLISPPPHHDIYSIEDLAQLIFDLKQINPKALISVKLVSEPGIGTIATGVAKAYADM
CCCEEECCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHHHHH
ITVSGYDGGTGASPLTSVKYAGSPWELGLAEVHQALVDNGLRHKIRLQVDGGLKTGTDVI
EEEECCCCCCCCCCCCCCEECCCCCCCCHHHHHHHHHCCCCCEEEEEEECCCCCCHHHHH
KAALLGAESFGFGTVPMIALGCKYLRICHLNNCATGVATQDKNLRDKHFHGLPERVMTYF
HHHHHCCCCCCCCCHHHHHHHHHHHEEEECCCCCCCCCCCCCCCCHHHHCCCHHHHHHHH
EFVAEEVREWMARLGVAKFEDLVGRSDWLYALAGQTEKQHGLDLSPILYQPQVRAGSSRT
HHHHHHHHHHHHHHCHHHHHHHHCCCCEEEEECCCCCHHCCCCCCCEEECCCCCCCCCCC
WKEINPPTDTGELNQRLLKDAADAISRGEGFSAAYSINNTDRSVGAALSGHIAACCGLKG
CCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHCCHHHHHCCCC
TKAPVSLSFNGTAGQSFGVWNAPGLEMSLCGDANDYVGKGMSGGKLSIYPPLGSAFQSER
CCCCEEEEECCCCCCCCCCCCCCCCEEEECCCCHHHHCCCCCCCEEEEECCCCCHHHCCC
TAIVGNTCLYGATGGQFFAAGQAGERFGVRNSGAVAVVEGLGDNGCEYMTGGIVVVLGKT
EEEEECCEEECCCCCCEEECCCCCCCCCCCCCCCEEEEECCCCCCCEEECCCEEEEECCC
GVNFGAGMTGGFAYVFDQFGRFGRRVNTEMVDTQKVESAIHQKHLKGLIEAHVKETGSEH
CCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
ARAILSDFDNWLDCFVLVKPKNVAVADLLKLEQPSPELAVKAG
HHHHHHHHHHHEEEEEEECCCCCHHHHHHHCCCCCCCEEEECC
>Mature Secondary Structure 
SLYHPSFERDNCGFGLIAQMDGEASHRIVRTAITGLDRMKHRGGIAADGRTGDGCGLLM
CCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHH
QLPIKFFESIAAENDWHLSRKFAVGMFFLSQDEEKVAAARFVLERELEKETLCIAGWREV
HHHHHHHHHHHCCCCCCHHHHHHHEEEEECCCHHHHHHHHHHHHHHHHHHHEEEECCCCC
PVNPDVLGEIGKASLPRIVQVLINAPIGWREKDLERRLYMARRRLEQQMTADPDFYVASL
CCCHHHHHHCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEC
SGQVIVYKGLMMPADLPAFYPDLADLRLESAICLFHQRFSTNTSPKWPLAQPFRYLAHNG
CCCEEEEECCCCCCCCCHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCC
EINTITGNRQWARARAYKFNSPLLPDLQQAAPFVNETGSDSSSLDNMLEMLLSGGMDLYR
CEEEEECCCHHHHHHHEECCCCCCCCHHHHCCCCCCCCCCHHHHHHHHHHHHHCCHHHHH
AMRLLIPPAWQSNPEMDEELKAFYDFNSMHMEPWDGPAGIVMTNGRHAACAVDRNGLRPS
HHHHHCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCEEEECCCEEEEEECCCCCCCC
RYVITKDRILTLASEVGIWDYQPDEVVEKGRVGPGELLVLDTLNGRLYQSFEIDNDLKRR
EEEEEHHHHHHHHHHCCCCCCCHHHHHHCCCCCCCCEEEEEECCCCEEEEECCCCHHHHC
HPYKEWMAKNSRTLKSAEEMSSEQHGASEFSRDTLLQYQKLFGYSREELEQVIWVLASQG
CCHHHHHHCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCC
EEAVGSMGDDTPMAVLSNKQRSLYDYFRQKFAQVTNPPIDPLREKHVMSLATCVGREQNL
CHHHHCCCCCCCHHHHCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCHHHH
FNETTGHAYRVMFNSPVLLFSDFNQLMSLDKAYYRANIVDLNYDPAEGLEGAIRRITDDA
HHCCCCCEEEEEECCCEEEEHHHHHHHHHHHHHHEEEEEEECCCCHHHHHHHHHHHHHHH
ERLARTGTTLLVLSDRAVAKNRQVIPAAMAVGAVQQMLVSKSLRCDTNIIVETASARDPH
HHHHHCCCEEEEEECCHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCC
HFAVLLGFGATAIYPYLVYESIADLAKRNDSADDMVALMLNFRYGIEKGLRKIMSKMGIS
EEEEEEECCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCHH
TVASYRCSQQFEAIGLARDVIELCFKGVVSRIEGVSFDHLAKDQHKLHQAAFRPHVSLQQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCC
GGLLKYVEGGEYHAFNPDVVNTLQASLISRDYSKYKAFAKHVDERPVAMLRDLLGVKGTL
CCEEEEEECCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCC
DAIPADTVEAAANLYPRFDSAAMSIGALSPEAHEALAIAMNRLGGRSNSGEGGEDPRRFG
CCCCCHHHHHHHHHCCCCCHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHCC
TEKNSAIKQIASGRFGVTAHYLINAEVLQIKVAQGAKPGEGGQLPGHKVSVEIAGLRYAR
CCHHHHHHHHHCCCCCEEEEEEEECEEEEEEEECCCCCCCCCCCCCCEEEEEEECEEECC
PGVTLISPPPHHDIYSIEDLAQLIFDLKQINPKALISVKLVSEPGIGTIATGVAKAYADM
CCCEEECCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHHHHH
ITVSGYDGGTGASPLTSVKYAGSPWELGLAEVHQALVDNGLRHKIRLQVDGGLKTGTDVI
EEEECCCCCCCCCCCCCCEECCCCCCCCHHHHHHHHHCCCCCEEEEEEECCCCCCHHHHH
KAALLGAESFGFGTVPMIALGCKYLRICHLNNCATGVATQDKNLRDKHFHGLPERVMTYF
HHHHHCCCCCCCCCHHHHHHHHHHHEEEECCCCCCCCCCCCCCCCHHHHCCCHHHHHHHH
EFVAEEVREWMARLGVAKFEDLVGRSDWLYALAGQTEKQHGLDLSPILYQPQVRAGSSRT
HHHHHHHHHHHHHHCHHHHHHHHCCCCEEEEECCCCCHHCCCCCCCEEECCCCCCCCCCC
WKEINPPTDTGELNQRLLKDAADAISRGEGFSAAYSINNTDRSVGAALSGHIAACCGLKG
CCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHCCHHHHHCCCC
TKAPVSLSFNGTAGQSFGVWNAPGLEMSLCGDANDYVGKGMSGGKLSIYPPLGSAFQSER
CCCCEEEEECCCCCCCCCCCCCCCCEEEECCCCHHHHCCCCCCCEEEEECCCCCHHHCCC
TAIVGNTCLYGATGGQFFAAGQAGERFGVRNSGAVAVVEGLGDNGCEYMTGGIVVVLGKT
EEEEECCEEECCCCCCEEECCCCCCCCCCCCCCCEEEEECCCCCCCEEECCCEEEEECCC
GVNFGAGMTGGFAYVFDQFGRFGRRVNTEMVDTQKVESAIHQKHLKGLIEAHVKETGSEH
CCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
ARAILSDFDNWLDCFVLVKPKNVAVADLLKLEQPSPELAVKAG
HHHHHHHHHHHEEEEEEECCCCCHHHHHHHCCCCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3326786; 9278503; 1673677; 2643092 [H]