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The map label for this gene is mtnN [H]

Identifier: 119773992

GI number: 119773992

Start: 1041113

End: 1041868

Strand: Reverse

Name: mtnN [H]

Synonym: Sama_0855

Alternate gene names: 119773992

Gene position: 1041868-1041113 (Counterclockwise)

Preceding gene: 119773993

Following gene: 119773991

Centisome position: 24.19

GC content: 53.57

Gene sequence:

>756_bases
GTGCCGGTCAGTCGACTGTGGTATATTGGCTGCCATTCTCTAAAGCAGTTCAAAGGCAAGTTTATGAAAATTGGTATTAT
CGGCGCCATGGAGCCCGAAGTTGCTCACCTTATTGCTTCTCTGGAAAACCCAGTTGTAAGCCAAATAGCCGGCATCGAAT
TCACCCAGGGTGAACTCAATGGCAAGCAGGTCATAGTGACCCGCTCCGGTATAGGCAAGGTCGCAGCAGCGCTCGCCACC
ACCCTGCTTATCGATAAGTTTGCTCCCGATTACGTGATTAATACCGGCTCAGCCGGTGGCTTTGTGGACAGCCTGACCAT
TGGTGATGTGGTGATTGGCAGTGAGGTGCGTTACCACGATGTGGACGTGACGGCTTTTGGCTATGAAATCGGCCAGATGG
CGCAGCAGCCGGCCGCCTTTGTGTGTGATGCCCACCTGGTAGAAGCCGCTAAAAATGCCGTGGCGAAACTGGGTGAGGTA
AAAACCGTAGCAGGCCTTATCTGTACCGGTGACAGCTTTATTTGCGACCCGGTCCGTACTGCAAAAATGCAGGCAGATTT
CCCCACCATGGCCGCCTGTGAAATGGAAGGTGCCGCCATCGGTCAGGTGTGCCATCAGTTCGCCACCCCATTTGTGGTGA
TCCGCTCTCTGTCGGATAATGCCAACAACGACAGCCCGGTCGACTTTGAGTCTTATCTGGTGAAAGCCGGTCATCACTCT
GCTCTGATGGTCATGGCGCTGATTGAAGGCCTGTAA

Upstream 100 bases:

>100_bases
GGAATCGGCCAAAGCCTGATCCCAACAACAAGTTGCTTGTGTCTTGCGCATCCAAAGGTTCGCCTGAGGATGCGCTTTTT
TATCTCTGCAGCTTGCCTGT

Downstream 100 bases:

>100_bases
ATGACCGAAAGCCAGTTTGTCAGCCAGCTGATTGCCCTGGATGGAGCCCTGTTTGAAGGCTTCCTTATCATCCTGTGCGC
GCTGCCACTGGCACGACTGG

Product: adenosylhomocysteine nucleosidase

Products: NA

Alternate protein names: MTA/SAH nucleosidase; MTAN; 5'-methylthioadenosine nucleosidase; MTA nucleosidase; S-adenosylhomocysteine nucleosidase; AdoHcy nucleosidase; SAH nucleosidase; SRH nucleosidase [H]

Number of amino acids: Translated: 251; Mature: 250

Protein sequence:

>251_residues
MPVSRLWYIGCHSLKQFKGKFMKIGIIGAMEPEVAHLIASLENPVVSQIAGIEFTQGELNGKQVIVTRSGIGKVAAALAT
TLLIDKFAPDYVINTGSAGGFVDSLTIGDVVIGSEVRYHDVDVTAFGYEIGQMAQQPAAFVCDAHLVEAAKNAVAKLGEV
KTVAGLICTGDSFICDPVRTAKMQADFPTMAACEMEGAAIGQVCHQFATPFVVIRSLSDNANNDSPVDFESYLVKAGHHS
ALMVMALIEGL

Sequences:

>Translated_251_residues
MPVSRLWYIGCHSLKQFKGKFMKIGIIGAMEPEVAHLIASLENPVVSQIAGIEFTQGELNGKQVIVTRSGIGKVAAALAT
TLLIDKFAPDYVINTGSAGGFVDSLTIGDVVIGSEVRYHDVDVTAFGYEIGQMAQQPAAFVCDAHLVEAAKNAVAKLGEV
KTVAGLICTGDSFICDPVRTAKMQADFPTMAACEMEGAAIGQVCHQFATPFVVIRSLSDNANNDSPVDFESYLVKAGHHS
ALMVMALIEGL
>Mature_250_residues
PVSRLWYIGCHSLKQFKGKFMKIGIIGAMEPEVAHLIASLENPVVSQIAGIEFTQGELNGKQVIVTRSGIGKVAAALATT
LLIDKFAPDYVINTGSAGGFVDSLTIGDVVIGSEVRYHDVDVTAFGYEIGQMAQQPAAFVCDAHLVEAAKNAVAKLGEVK
TVAGLICTGDSFICDPVRTAKMQADFPTMAACEMEGAAIGQVCHQFATPFVVIRSLSDNANNDSPVDFESYLVKAGHHSA
LMVMALIEGL

Specific function: Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively [H]

COG id: COG0775

COG function: function code F; Nucleoside phosphorylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PNP/UDP phosphorylase family. MtnN subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786354, Length=230, Percent_Identity=49.5652173913044, Blast_Score=191, Evalue=4e-50,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010049
- InterPro:   IPR018017
- InterPro:   IPR000845 [H]

Pfam domain/function: PF01048 PNP_UDP_1 [H]

EC number: =3.2.2.9 [H]

Molecular weight: Translated: 26593; Mature: 26462

Theoretical pI: Translated: 5.04; Mature: 5.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPVSRLWYIGCHSLKQFKGKFMKIGIIGAMEPEVAHLIASLENPVVSQIAGIEFTQGELN
CCCCCEEEHHHHHHHHHCCCEEEEEEEECCCHHHHHHHHHHCCHHHHHHCCCEEECCCCC
GKQVIVTRSGIGKVAAALATTLLIDKFAPDYVINTGSAGGFVDSLTIGDVVIGSEVRYHD
CCEEEEECCCHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCEECEEECCEEECCCEEEEE
VDVTAFGYEIGQMAQQPAAFVCDAHLVEAAKNAVAKLGEVKTVAGLICTGDSFICDPVRT
CEEEEHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCEEECCHHH
AKMQADFPTMAACEMEGAAIGQVCHQFATPFVVIRSLSDNANNDSPVDFESYLVKAGHHS
HHHCCCCCCHHHHCCCCHHHHHHHHHHCCHHEEEEECCCCCCCCCCCCHHHHHHHCCCHH
ALMVMALIEGL
HHHHHHHHHCC
>Mature Secondary Structure 
PVSRLWYIGCHSLKQFKGKFMKIGIIGAMEPEVAHLIASLENPVVSQIAGIEFTQGELN
CCCCEEEHHHHHHHHHCCCEEEEEEEECCCHHHHHHHHHHCCHHHHHHCCCEEECCCCC
GKQVIVTRSGIGKVAAALATTLLIDKFAPDYVINTGSAGGFVDSLTIGDVVIGSEVRYHD
CCEEEEECCCHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCEECEEECCEEECCCEEEEE
VDVTAFGYEIGQMAQQPAAFVCDAHLVEAAKNAVAKLGEVKTVAGLICTGDSFICDPVRT
CEEEEHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCEEECCHHH
AKMQADFPTMAACEMEGAAIGQVCHQFATPFVVIRSLSDNANNDSPVDFESYLVKAGHHS
HHHCCCCCCHHHHCCCCHHHHHHHHHHCCHHEEEEECCCCCCCCCCCCHHHHHHHCCCHH
ALMVMALIEGL
HHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA