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The map label for this gene is holC [H]

Identifier: 119773928

GI number: 119773928

Start: 975962

End: 976417

Strand: Reverse

Name: holC [H]

Synonym: Sama_0791

Alternate gene names: 119773928

Gene position: 976417-975962 (Counterclockwise)

Preceding gene: 119773929

Following gene: 119773927

Centisome position: 22.67

GC content: 57.02

Gene sequence:

>456_bases
ATGACCCAGGCACTCTTTTACGTACTTCCGCCGTCCCAAATGAGGGATGCTGCCGAGCTGCTGGCCTGCCGTCTGGCGGC
GTTTCATTACCGCCGCGGCGCCTGGGTCTATATTCACTGCAACGATGAATCCCAAAGCTTTGCCATCGACGAGCAACTTT
GGCAGTTTGACCCCAACGATTTTGTGCCCCACAACCTCAAGGGTGAAGGGCCTCTGGGGGGCGCGCCGGTGGAAATCGGT
CACGATCGCCTCGGGCCGTCAAAAAACCGCGGCATTCTGATAAATCTTGCAGAAAAAGTACCGCCTTTTGCGGTACACTT
TGGCCACTTTATCGACTTTGTCGCCGGTGACGAGGCCACCAAGGCACTGGCACGGCTGCGCTTTCGCGAGCTTCGCGGCC
TTGGCATCGAGCCATCCACTCAGGATTTGGCGACACAACCCCTTAATCTAGTTTGA

Upstream 100 bases:

>100_bases
CAGCGCGCCAATTTGTCCGCCCGGCTTTATGTCGGGCGCCCAACTAAGTTAGAATCCGGACTTATTGTTTACGCACAGGT
TGTTTACGCACAGGCCCACC

Downstream 100 bases:

>100_bases
GAAAATCTGATCCCCATGGAAAAGACATACAATCCACAGTCCATCGAACAGGCCCTCTACCGCGTTTGGGAAGAAAAGGG
TTACTTCAAGCCACACGGTG

Product: DNA polymerase III, chi subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 151; Mature: 150

Protein sequence:

>151_residues
MTQALFYVLPPSQMRDAAELLACRLAAFHYRRGAWVYIHCNDESQSFAIDEQLWQFDPNDFVPHNLKGEGPLGGAPVEIG
HDRLGPSKNRGILINLAEKVPPFAVHFGHFIDFVAGDEATKALARLRFRELRGLGIEPSTQDLATQPLNLV

Sequences:

>Translated_151_residues
MTQALFYVLPPSQMRDAAELLACRLAAFHYRRGAWVYIHCNDESQSFAIDEQLWQFDPNDFVPHNLKGEGPLGGAPVEIG
HDRLGPSKNRGILINLAEKVPPFAVHFGHFIDFVAGDEATKALARLRFRELRGLGIEPSTQDLATQPLNLV
>Mature_150_residues
TQALFYVLPPSQMRDAAELLACRLAAFHYRRGAWVYIHCNDESQSFAIDEQLWQFDPNDFVPHNLKGEGPLGGAPVEIGH
DRLGPSKNRGILINLAEKVPPFAVHFGHFIDFVAGDEATKALARLRFRELRGLGIEPSTQDLATQPLNLV

Specific function: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity [H]

COG id: COG2927

COG function: function code L; DNA polymerase III, chi subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1790709, Length=143, Percent_Identity=42.6573426573427, Blast_Score=110, Evalue=3e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007459 [H]

Pfam domain/function: PF04364 DNA_pol3_chi [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 16849; Mature: 16718

Theoretical pI: Translated: 6.23; Mature: 6.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQALFYVLPPSQMRDAAELLACRLAAFHYRRGAWVYIHCNDESQSFAIDEQLWQFDPND
CCCEEEEEECCHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCEEHHHHHHHCCCCC
FVPHNLKGEGPLGGAPVEIGHDRLGPSKNRGILINLAEKVPPFAVHFGHFIDFVAGDEAT
CCCCCCCCCCCCCCCCEEECCCCCCCCCCCCEEEEEHHHCCCCEEHHHHHHHHHCCCHHH
KALARLRFRELRGLGIEPSTQDLATQPLNLV
HHHHHHHHHHHHCCCCCCCCHHHHCCCCCCC
>Mature Secondary Structure 
TQALFYVLPPSQMRDAAELLACRLAAFHYRRGAWVYIHCNDESQSFAIDEQLWQFDPND
CCEEEEEECCHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCEEHHHHHHHCCCCC
FVPHNLKGEGPLGGAPVEIGHDRLGPSKNRGILINLAEKVPPFAVHFGHFIDFVAGDEAT
CCCCCCCCCCCCCCCCEEECCCCCCCCCCCCEEEEEHHHCCCCEEHHHHHHHHHCCCHHH
KALARLRFRELRGLGIEPSTQDLATQPLNLV
HHHHHHHHHHHHCCCCCCCCHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800; 7959067 [H]