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The map label for this gene is gluQ

Identifier: 119773916

GI number: 119773916

Start: 961689

End: 962561

Strand: Reverse

Name: gluQ

Synonym: Sama_0779

Alternate gene names: 119773916

Gene position: 962561-961689 (Counterclockwise)

Preceding gene: 119773917

Following gene: 119773915

Centisome position: 22.35

GC content: 58.88

Gene sequence:

>873_bases
ATGTCTTATTCCCCCTACATTGGCCGTTTTGCCCCCTCCCCCTCTGGCTCACTGCATTTTGGCTCGCTGATTGCCGCCCT
GGGCAGCTTCCTGCGCGCCCGCAGTCAGGGTGGACAGTGGCTGGTGCGCATCGAAGACATAGACCCGCCGCGGGAAGTGC
CCGGCGCCGCCGACGACATCCTCCGCACTCTGGACGCCTTTGGATTGCACTGGGATGGCAAACTGATGTACCAAAGTCAG
CGCACCGAGGCCTATCAGGCCAAAATCGATGTGCTGCTGGCAAGCGGCGAGGCCTATTTTTGCCAATGCACTCGCAAGCA
AATTCAGGCCATAGGTGGGGTTTACGATGGTCGCTGCCGCCAACTTGGCCATCAAAGCGGTGCCATACGTATCGTTAATC
GTGCCCGGGTGAATCATTTTCACGATGGCCTGATGGGCGAGGTAGCAGTGCCAGACAGTTTTGCCGCCGAAGACTTTATC
ATCAAGCGCAGCGATGGCCTTTACGCCTACCAGCTTGCGGTGGTGATGGACGATGCCAAAACCGGCATTACCGAGGTGGT
GCGCGGCGCTGACCTGATTGAAGCCAGTTGCCGTCAGCTGAGCCTGTTCAACCAATTTGGCTATCAGGCACCTGCCTGGA
TGCACCTGCCGCTGGCGTGCGCCGAGGCAGGATTCAAGCTGTCGAAACAAAACCATGCCACACCAGTAGACAAGGCCAAT
CCCCTGCCGGCTCTCAAGGCTGCGCTGGCATTTTTGGGTCAGCCAATACCCGATGCCCACAGCGTCGAAAGCCTGCTGGC
ACAGGCAGTGGCGGACTTTTCTGTGGCCTCCATTCCACGGCGGCGGGAAATCCTCATTGACGGTGGTGGCTAA

Upstream 100 bases:

>100_bases
AGATCAAAGAAAGGCAGATGGCTGGTTAATCCCCATCCACTGCAATTCAAAAGCGGGGCTCAGGCCCCGCTTGGCATTTC
AGGAACCTGTTAACAGCGCC

Downstream 100 bases:

>100_bases
GGCGCCTGCACACTGTCAATTAACCCCATTTGGGGTTATCATACCCGCCAGATTTTTAACCCCTAGTTAAGCTCAAGAGG
TGTACCATTTTTCGCCGTAT

Product: glutamyl-tRNA synthetase domain-containing protein

Products: NA

Alternate protein names: Glu-Q-RSs

Number of amino acids: Translated: 290; Mature: 289

Protein sequence:

>290_residues
MSYSPYIGRFAPSPSGSLHFGSLIAALGSFLRARSQGGQWLVRIEDIDPPREVPGAADDILRTLDAFGLHWDGKLMYQSQ
RTEAYQAKIDVLLASGEAYFCQCTRKQIQAIGGVYDGRCRQLGHQSGAIRIVNRARVNHFHDGLMGEVAVPDSFAAEDFI
IKRSDGLYAYQLAVVMDDAKTGITEVVRGADLIEASCRQLSLFNQFGYQAPAWMHLPLACAEAGFKLSKQNHATPVDKAN
PLPALKAALAFLGQPIPDAHSVESLLAQAVADFSVASIPRRREILIDGGG

Sequences:

>Translated_290_residues
MSYSPYIGRFAPSPSGSLHFGSLIAALGSFLRARSQGGQWLVRIEDIDPPREVPGAADDILRTLDAFGLHWDGKLMYQSQ
RTEAYQAKIDVLLASGEAYFCQCTRKQIQAIGGVYDGRCRQLGHQSGAIRIVNRARVNHFHDGLMGEVAVPDSFAAEDFI
IKRSDGLYAYQLAVVMDDAKTGITEVVRGADLIEASCRQLSLFNQFGYQAPAWMHLPLACAEAGFKLSKQNHATPVDKAN
PLPALKAALAFLGQPIPDAHSVESLLAQAVADFSVASIPRRREILIDGGG
>Mature_289_residues
SYSPYIGRFAPSPSGSLHFGSLIAALGSFLRARSQGGQWLVRIEDIDPPREVPGAADDILRTLDAFGLHWDGKLMYQSQR
TEAYQAKIDVLLASGEAYFCQCTRKQIQAIGGVYDGRCRQLGHQSGAIRIVNRARVNHFHDGLMGEVAVPDSFAAEDFII
KRSDGLYAYQLAVVMDDAKTGITEVVRGADLIEASCRQLSLFNQFGYQAPAWMHLPLACAEAGFKLSKQNHATPVDKANP
LPALKAALAFLGQPIPDAHSVESLLAQAVADFSVASIPRRREILIDGGG

Specific function: Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble positi

COG id: COG0008

COG function: function code J; Glutamyl- and glutaminyl-tRNA synthetases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily

Homologues:

Organism=Homo sapiens, GI134288884, Length=250, Percent_Identity=33.6, Blast_Score=130, Evalue=1e-30,
Organism=Escherichia coli, GI226510925, Length=285, Percent_Identity=55.7894736842105, Blast_Score=316, Evalue=1e-87,
Organism=Escherichia coli, GI1788743, Length=244, Percent_Identity=35.2459016393443, Blast_Score=145, Evalue=3e-36,
Organism=Caenorhabditis elegans, GI71993394, Length=252, Percent_Identity=34.5238095238095, Blast_Score=122, Evalue=2e-28,
Organism=Saccharomyces cerevisiae, GI6324540, Length=252, Percent_Identity=32.9365079365079, Blast_Score=145, Evalue=5e-36,
Organism=Drosophila melanogaster, GI24665321, Length=249, Percent_Identity=36.5461847389558, Blast_Score=137, Evalue=7e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GLUQ_SHEAM (A1S3N0)

Other databases:

- EMBL:   CP000507
- RefSeq:   YP_926656.1
- ProteinModelPortal:   A1S3N0
- SMR:   A1S3N0
- STRING:   A1S3N0
- GeneID:   4603031
- GenomeReviews:   CP000507_GR
- KEGG:   saz:Sama_0779
- NMPDR:   fig|326297.7.peg.731
- eggNOG:   COG0008
- HOGENOM:   HBG628189
- OMA:   IIKRSDG
- PhylomeDB:   A1S3N0
- ProtClustDB:   PRK05710
- GO:   GO:0005737
- GO:   GO:0006412
- HAMAP:   MF_01428
- InterPro:   IPR022380
- InterPro:   IPR000924
- InterPro:   IPR020058
- InterPro:   IPR014729
- Gene3D:   G3DSA:3.40.50.620
- PANTHER:   PTHR10119
- PRINTS:   PR00987
- TIGRFAMs:   TIGR03838

Pfam domain/function: PF00749 tRNA-synt_1c

EC number: NA

Molecular weight: Translated: 31485; Mature: 31354

Theoretical pI: Translated: 6.94; Mature: 6.94

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: BINDING 45-45 BINDING 170-170 BINDING 188-188 BINDING 229-229

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSYSPYIGRFAPSPSGSLHFGSLIAALGSFLRARSQGGQWLVRIEDIDPPREVPGAADDI
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCHHHH
LRTLDAFGLHWDGKLMYQSQRTEAYQAKIDVLLASGEAYFCQCTRKQIQAIGGVYDGRCR
HHHHHHHCCCCCCEEEEECHHHHHHHHEEEEEEECCCEEEHHHHHHHHHHHCCCCCCHHH
QLGHQSGAIRIVNRARVNHFHDGLMGEVAVPDSFAAEDFIIKRSDGLYAYQLAVVMDDAK
HHCCCCCCEEEEHHHHHHHHHCCCCCCEECCCCCCCCCEEEECCCCCEEEEEEEEECCHH
TGITEVVRGADLIEASCRQLSLFNQFGYQAPAWMHLPLACAEAGFKLSKQNHATPVDKAN
HHHHHHHHCHHHHHHHHHHHHHHHHCCCCCCCEEECHHHHHHCCCEECCCCCCCCCCCCC
PLPALKAALAFLGQPIPDAHSVESLLAQAVADFSVASIPRRREILIDGGG
CCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCC
>Mature Secondary Structure 
SYSPYIGRFAPSPSGSLHFGSLIAALGSFLRARSQGGQWLVRIEDIDPPREVPGAADDI
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCHHHH
LRTLDAFGLHWDGKLMYQSQRTEAYQAKIDVLLASGEAYFCQCTRKQIQAIGGVYDGRCR
HHHHHHHCCCCCCEEEEECHHHHHHHHEEEEEEECCCEEEHHHHHHHHHHHCCCCCCHHH
QLGHQSGAIRIVNRARVNHFHDGLMGEVAVPDSFAAEDFIIKRSDGLYAYQLAVVMDDAK
HHCCCCCCEEEEHHHHHHHHHCCCCCCEECCCCCCCCCEEEECCCCCEEEEEEEEECCHH
TGITEVVRGADLIEASCRQLSLFNQFGYQAPAWMHLPLACAEAGFKLSKQNHATPVDKAN
HHHHHHHHCHHHHHHHHHHHHHHHHCCCCCCCEEECHHHHHHCCCEECCCCCCCCCCCCC
PLPALKAALAFLGQPIPDAHSVESLLAQAVADFSVASIPRRREILIDGGG
CCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA