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The map label for this gene is hcp1 [H]

Identifier: 119773879

GI number: 119773879

Start: 908537

End: 909067

Strand: Reverse

Name: hcp1 [H]

Synonym: Sama_0741

Alternate gene names: 119773879

Gene position: 909067-908537 (Counterclockwise)

Preceding gene: 119773882

Following gene: 119773875

Centisome position: 21.11

GC content: 54.24

Gene sequence:

>531_bases
ATGAGAGTCAGTCAATGGAAGCGACTTGGTATGCTATCGGCCCTGGCACTGGGAATGACGGTGGGTTCGGCTCAGGGGGC
TGGTTATTTGAAAATTGGCGATATCAAGGGCGAAAGCCAAAACGATGCTCACCGGGAGGAAATCGAACTTCTCAGCTGGA
GCTGGGGCACCAACAGCAGCATGAATGGCTCGGGTAGCCTCTGCATCATGGATGTTGCTTTGGTCAAATATACCGACAGT
GCCACCGTGGATATTTTGATGGGGCAGATGATGGGCACCCAGTACCCCGATGCCGAAATTTCAATGACCCAAAGCGGCAG
CGTGCGCACTGAGGACTACTTCAAGATGCGCATGCGCAATGTCACGGTAACCAGTTATCAAACCGGTGGCAGTGGCTATG
AGCGCATGACTGAGAGTATCACTCTGCATTTCGATGAAGCGTCAATTGAGTACCGTCGTCCCGGGCCAGATGGCAGCCCA
GGCGCTCCCGAAGTCACCCGTATCAGCTCCAGCAGCCATAAGTGCCACTGA

Upstream 100 bases:

>100_bases
TGAGATTTAGTCACCCAAGCAGGAATAAGCGCTGGGACCTACACTTTAGTCCTGTGCCTGCATGGGCGGCACAGTTCTGC
AATCATAAGGAGAGATTCTG

Downstream 100 bases:

>100_bases
ATCAGGCTATGGGCACATTCATGGATGTGCCCAAGCCCAGGATTTTGCCAGAGCACATACCTAATCGAGGTCTTTCAGGG
TTGCCATCCCCAGCTGTCGC

Product: hemolysin-coregulated protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 176; Mature: 176

Protein sequence:

>176_residues
MRVSQWKRLGMLSALALGMTVGSAQGAGYLKIGDIKGESQNDAHREEIELLSWSWGTNSSMNGSGSLCIMDVALVKYTDS
ATVDILMGQMMGTQYPDAEISMTQSGSVRTEDYFKMRMRNVTVTSYQTGGSGYERMTESITLHFDEASIEYRRPGPDGSP
GAPEVTRISSSSHKCH

Sequences:

>Translated_176_residues
MRVSQWKRLGMLSALALGMTVGSAQGAGYLKIGDIKGESQNDAHREEIELLSWSWGTNSSMNGSGSLCIMDVALVKYTDS
ATVDILMGQMMGTQYPDAEISMTQSGSVRTEDYFKMRMRNVTVTSYQTGGSGYERMTESITLHFDEASIEYRRPGPDGSP
GAPEVTRISSSSHKCH
>Mature_176_residues
MRVSQWKRLGMLSALALGMTVGSAQGAGYLKIGDIKGESQNDAHREEIELLSWSWGTNSSMNGSGSLCIMDVALVKYTDS
ATVDILMGQMMGTQYPDAEISMTQSGSVRTEDYFKMRMRNVTVTSYQTGGSGYERMTESITLHFDEASIEYRRPGPDGSP
GAPEVTRISSSSHKCH

Specific function: Required for assembly of the protein secretion apparatus HSI-I. Actively secreted during chronic infection of cystic fibrosis patients [H]

COG id: COG3157

COG function: function code S; Hemolysin-coregulated protein (uncharacterized)

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hcp1 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017728
- InterPro:   IPR008514 [H]

Pfam domain/function: PF05638 DUF796 [H]

EC number: NA

Molecular weight: Translated: 19236; Mature: 19236

Theoretical pI: Translated: 5.63; Mature: 5.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
6.8 %Met     (Translated Protein)
8.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
6.8 %Met     (Mature Protein)
8.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVSQWKRLGMLSALALGMTVGSAQGAGYLKIGDIKGESQNDAHREEIELLSWSWGTNSS
CCCHHHHHHHHHHHHHHHHEECCCCCCCEEEEECCCCCCCCCCCHHHEEEEEECCCCCCC
MNGSGSLCIMDVALVKYTDSATVDILMGQMMGTQYPDAEISMTQSGSVRTEDYFKMRMRN
CCCCCCEEEEEEEEEEECCCCHHHHHHHHHHCCCCCCCEEEEECCCCCCCHHHHHHHHHE
VTVTSYQTGGSGYERMTESITLHFDEASIEYRRPGPDGSPGAPEVTRISSSSHKCH
EEEEEEECCCCHHHHHCEEEEEEEECCCEEEECCCCCCCCCCCCEEEECCCCCCCC
>Mature Secondary Structure
MRVSQWKRLGMLSALALGMTVGSAQGAGYLKIGDIKGESQNDAHREEIELLSWSWGTNSS
CCCHHHHHHHHHHHHHHHHEECCCCCCCEEEEECCCCCCCCCCCHHHEEEEEECCCCCCC
MNGSGSLCIMDVALVKYTDSATVDILMGQMMGTQYPDAEISMTQSGSVRTEDYFKMRMRN
CCCCCCEEEEEEEEEEECCCCHHHHHHHHHHCCCCCCCEEEEECCCCCCCHHHHHHHHHE
VTVTSYQTGGSGYERMTESITLHFDEASIEYRRPGPDGSPGAPEVTRISSSSHKCH
EEEEEEECCCCHHHHHCEEEEEEEECCCEEEECCCCCCCCCCCCEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]