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The map label for this gene is csrD [H]

Identifier: 119773589

GI number: 119773589

Start: 554989

End: 556896

Strand: Direct

Name: csrD [H]

Synonym: Sama_0449

Alternate gene names: 119773589

Gene position: 554989-556896 (Clockwise)

Preceding gene: 119773588

Following gene: 119773590

Centisome position: 12.89

GC content: 52.99

Gene sequence:

>1908_bases
ATGCAACTGACTCGCATGCTGACCAAAAAACTCATCAGCTTCTGGATGATGTCGCTGGCGGCAGTCGCTTTTGTGTTTTT
GCTCAGCGCCCTGATGAGTTTTGTACAGCTGACCTACCGCTTTCAACAGCAAAAGGTCGCCGAGCTGGAAACCATGTTGG
TTAACCATTATCAGCACCAGAGCAGTTGGGAGCTGGATAGCTGGTTGCCGCCCATGCTGCTGGCCTATAACACAGTGAGT
TTCCGTTTAACCCGGGGAGATGAACTGGTATTTGAATATCAGGGCAATCTGGGTTCGGATCAGACTGTAGTTTACGAGCG
TGCCCTCTATGCCAATGATGCGCTCGAGATGCGACTGGAGCTTCCCCGTCCGTTTTCGGCCCACAGACTTGGTTGGCGTG
AGCTGATGATTCTGCTGGTAGGTATAGTGGCGGTAGCAGGGTTTGTTCGCTTCGGATTCCTGTGGTTTTCTGCCGAGCTT
GAAGGCATAGAGGCGCTGGCGCAGCGCAGTAAACTTATTCTCGATGGCAAGCTGGATGAGGCGGCCAAAACCCCGGGGAA
CGGTAAACCACGACTAATCAATCGTGCGCTCTCAAGACTGCTTGCTGAACTTGCCGATGCCCACAAAGAGCGGGCCCGCT
TCGATAAATTTATTCGCTCCAATACCTTTCTCGATCCCCAAACCCGGATAGGAAACAGGCTGTTTTTACAGAACCGTCTC
AACGCTCTCTCAAGCGACCAGGGAATGCTGGCACCCGGTGTCTTGTATCTGCTTGAAATGGAGGATCTGGATATTTTGCA
GCAGGAGGCTGGCGATGAAGTGGTGCTTGAGCTGCTCCACAGCACCATCAATGCCATAAACCTGGTGCTGCAAACCCAGG
CCAACAGTATTTTTGCCCGCCGCTCCCATAATCAGCTGGCTATCGTAGTGCCGCAAATCTCCCTGGTGGAGGCCGATGCC
CTTGCTGATAAATTGCTGAAAATTTGTCTGGCGCAGCCGCTGCCGAAAATTGAAGAAGCCGATAACTTTTTCCATCTGGG
GGGCGCTTACTTTAAAGAGGGCGACATGCCTGAACCCTTGCTGGACGAGGCTGACATGGCTCTGCGCGCTGCGCAGCTGC
AGGGTGCCAGTGGCTGGTTTATGTATGACAAGGGCGCTGTGGATCAAGAGTTTGCCAAGGGCTCAGTACGCTGGCGCTCT
TTTCTTGAAAATGCTCTGGTTAACCGAAATTTCGTTACTTTTGCCCAGCCTGTGTGCGAAGGCGATGGCAGTCATCATCA
CCATGAAATTTTTACCCGGGTGCGGGACCCCATGGGTAGCCTGGTCAGGGCGACTCTGTTTATCCCCATGGCGGTGAAAT
GTGGCCTGATGCCGCAAATCGAGCGGCAGGTGGTGGAGCGAACCCTGTTTGAGCTGATGTCAGATACCGGCACTGCCAAG
CGACATTACAGCATCAACCTGAGTGTGGATTCCCTTACCAGCCGTGCCTTTGTGCGCTGGCTGCAAACCACCTTGCTCGA
ATACCGTCATCTGGCATCCCGGCTGGTGTTTGAGGTTACCGAAGATATGGTGATGAAGCACCGAAGTCAGCTTGAGCCCA
AGCTTAATATGCTGCGTAAAATGGGCAGCCGTATCTGTGTGGACCATGTTGGGCAGCAGGTAGTCAGCACTCAGTATATC
CGTGAGTTGGGTTTTAACTTTATCAAGCTGCACCGCTCAGTGGTCCGTCAAATAGATTTACGCCCCGAGAATCAGCTGTT
TGTCCGCAGTCTAATCGGCAGTTTGTACCGCACCGATGTACAGGTGTTTGCCGAGGGGGTTGGTTCCTTTGAAGAGTGGC
AAACACTGCAAATTTTGGGGGTCAGTGCAGGACAGGGCACCTACTTTGGCGATCCACAGCAGATCTGA

Upstream 100 bases:

>100_bases
CCTTTTGTTATTGAGTACCTGATAATTTTTAACAATTTGCAGTGTCCCGCCGGGGCCTTGCCGGCACATAAGAACTAAAA
CATCAGGACGGCCTCATCTC

Downstream 100 bases:

>100_bases
GTGGCAATTTGTGCCAAAACCCTTGTGAAACACAGGCCCTCGGCCTATCTTATGGGGTAATATCTGCATAATACTTATTA
AAAATAACTAATTAGTACGC

Product: regulatory protein CsrD

Products: NA

Alternate protein names: Regulator of CsrB and CsrC decay CsrD [H]

Number of amino acids: Translated: 635; Mature: 635

Protein sequence:

>635_residues
MQLTRMLTKKLISFWMMSLAAVAFVFLLSALMSFVQLTYRFQQQKVAELETMLVNHYQHQSSWELDSWLPPMLLAYNTVS
FRLTRGDELVFEYQGNLGSDQTVVYERALYANDALEMRLELPRPFSAHRLGWRELMILLVGIVAVAGFVRFGFLWFSAEL
EGIEALAQRSKLILDGKLDEAAKTPGNGKPRLINRALSRLLAELADAHKERARFDKFIRSNTFLDPQTRIGNRLFLQNRL
NALSSDQGMLAPGVLYLLEMEDLDILQQEAGDEVVLELLHSTINAINLVLQTQANSIFARRSHNQLAIVVPQISLVEADA
LADKLLKICLAQPLPKIEEADNFFHLGGAYFKEGDMPEPLLDEADMALRAAQLQGASGWFMYDKGAVDQEFAKGSVRWRS
FLENALVNRNFVTFAQPVCEGDGSHHHHEIFTRVRDPMGSLVRATLFIPMAVKCGLMPQIERQVVERTLFELMSDTGTAK
RHYSINLSVDSLTSRAFVRWLQTTLLEYRHLASRLVFEVTEDMVMKHRSQLEPKLNMLRKMGSRICVDHVGQQVVSTQYI
RELGFNFIKLHRSVVRQIDLRPENQLFVRSLIGSLYRTDVQVFAEGVGSFEEWQTLQILGVSAGQGTYFGDPQQI

Sequences:

>Translated_635_residues
MQLTRMLTKKLISFWMMSLAAVAFVFLLSALMSFVQLTYRFQQQKVAELETMLVNHYQHQSSWELDSWLPPMLLAYNTVS
FRLTRGDELVFEYQGNLGSDQTVVYERALYANDALEMRLELPRPFSAHRLGWRELMILLVGIVAVAGFVRFGFLWFSAEL
EGIEALAQRSKLILDGKLDEAAKTPGNGKPRLINRALSRLLAELADAHKERARFDKFIRSNTFLDPQTRIGNRLFLQNRL
NALSSDQGMLAPGVLYLLEMEDLDILQQEAGDEVVLELLHSTINAINLVLQTQANSIFARRSHNQLAIVVPQISLVEADA
LADKLLKICLAQPLPKIEEADNFFHLGGAYFKEGDMPEPLLDEADMALRAAQLQGASGWFMYDKGAVDQEFAKGSVRWRS
FLENALVNRNFVTFAQPVCEGDGSHHHHEIFTRVRDPMGSLVRATLFIPMAVKCGLMPQIERQVVERTLFELMSDTGTAK
RHYSINLSVDSLTSRAFVRWLQTTLLEYRHLASRLVFEVTEDMVMKHRSQLEPKLNMLRKMGSRICVDHVGQQVVSTQYI
RELGFNFIKLHRSVVRQIDLRPENQLFVRSLIGSLYRTDVQVFAEGVGSFEEWQTLQILGVSAGQGTYFGDPQQI
>Mature_635_residues
MQLTRMLTKKLISFWMMSLAAVAFVFLLSALMSFVQLTYRFQQQKVAELETMLVNHYQHQSSWELDSWLPPMLLAYNTVS
FRLTRGDELVFEYQGNLGSDQTVVYERALYANDALEMRLELPRPFSAHRLGWRELMILLVGIVAVAGFVRFGFLWFSAEL
EGIEALAQRSKLILDGKLDEAAKTPGNGKPRLINRALSRLLAELADAHKERARFDKFIRSNTFLDPQTRIGNRLFLQNRL
NALSSDQGMLAPGVLYLLEMEDLDILQQEAGDEVVLELLHSTINAINLVLQTQANSIFARRSHNQLAIVVPQISLVEADA
LADKLLKICLAQPLPKIEEADNFFHLGGAYFKEGDMPEPLLDEADMALRAAQLQGASGWFMYDKGAVDQEFAKGSVRWRS
FLENALVNRNFVTFAQPVCEGDGSHHHHEIFTRVRDPMGSLVRATLFIPMAVKCGLMPQIERQVVERTLFELMSDTGTAK
RHYSINLSVDSLTSRAFVRWLQTTLLEYRHLASRLVFEVTEDMVMKHRSQLEPKLNMLRKMGSRICVDHVGQQVVSTQYI
RELGFNFIKLHRSVVRQIDLRPENQLFVRSLIGSLYRTDVQVFAEGVGSFEEWQTLQILGVSAGQGTYFGDPQQI

Specific function: Serves as a specificity factor required for RNase E- mediated decay of the small global regulatory RNAs CsrB and CsrC, it is probably not a nuclease. Nor does its activity involve c-di- GMP, despite its domain composition. Positively modulates motility ge

COG id: COG2200

COG function: function code T; FOG: EAL domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GGDEF domain [H]

Homologues:

Organism=Escherichia coli, GI1789650, Length=638, Percent_Identity=28.8401253918495, Blast_Score=254, Evalue=1e-68,
Organism=Escherichia coli, GI87081845, Length=253, Percent_Identity=26.8774703557312, Blast_Score=86, Evalue=9e-18,
Organism=Escherichia coli, GI1788849, Length=244, Percent_Identity=27.4590163934426, Blast_Score=83, Evalue=7e-17,
Organism=Escherichia coli, GI87081921, Length=449, Percent_Identity=23.8307349665924, Blast_Score=80, Evalue=6e-16,
Organism=Escherichia coli, GI1790496, Length=245, Percent_Identity=26.530612244898, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1787541, Length=452, Percent_Identity=23.0088495575221, Blast_Score=67, Evalue=4e-12,
Organism=Escherichia coli, GI87081743, Length=233, Percent_Identity=25.3218884120172, Blast_Score=66, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF [H]

EC number: NA

Molecular weight: Translated: 72264; Mature: 72264

Theoretical pI: Translated: 6.73; Mature: 6.73

Prosite motif: PS50883 EAL ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQLTRMLTKKLISFWMMSLAAVAFVFLLSALMSFVQLTYRFQQQKVAELETMLVNHYQHQ
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
SSWELDSWLPPMLLAYNTVSFRLTRGDELVFEYQGNLGSDQTVVYERALYANDALEMRLE
CCCCHHHCCCHHHHHHCCEEEEEECCCEEEEEECCCCCCCCHHHHHHHHHHCCHHHHHCC
LPRPFSAHRLGWRELMILLVGIVAVAGFVRFGFLWFSAELEGIEALAQRSKLILDGKLDE
CCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCHH
AAKTPGNGKPRLINRALSRLLAELADAHKERARFDKFIRSNTFLDPQTRIGNRLFLQNRL
HHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCHHHHHHH
NALSSDQGMLAPGVLYLLEMEDLDILQQEAGDEVVLELLHSTINAINLVLQTQANSIFAR
HHHCCCCCCCCCCCEEEEEHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RSHNQLAIVVPQISLVEADALADKLLKICLAQPLPKIEEADNFFHLGGAYFKEGDMPEPL
CCCCCEEEEECCHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCEEECCCHHHCCCCCCCHH
LDEADMALRAAQLQGASGWFMYDKGAVDQEFAKGSVRWRSFLENALVNRNFVTFAQPVCE
HHHHHHHHHHHHHCCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHC
GDGSHHHHEIFTRVRDPMGSLVRATLFIPMAVKCGLMPQIERQVVERTLFELMSDTGTAK
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCC
RHYSINLSVDSLTSRAFVRWLQTTLLEYRHLASRLVFEVTEDMVMKHRSQLEPKLNMLRK
EEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
MGSRICVDHVGQQVVSTQYIRELGFNFIKLHRSVVRQIDLRPENQLFVRSLIGSLYRTDV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
QVFAEGVGSFEEWQTLQILGVSAGQGTYFGDPQQI
HHHHHHCCCHHHCCEEEEEEEECCCCCCCCCCCCC
>Mature Secondary Structure
MQLTRMLTKKLISFWMMSLAAVAFVFLLSALMSFVQLTYRFQQQKVAELETMLVNHYQHQ
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
SSWELDSWLPPMLLAYNTVSFRLTRGDELVFEYQGNLGSDQTVVYERALYANDALEMRLE
CCCCHHHCCCHHHHHHCCEEEEEECCCEEEEEECCCCCCCCHHHHHHHHHHCCHHHHHCC
LPRPFSAHRLGWRELMILLVGIVAVAGFVRFGFLWFSAELEGIEALAQRSKLILDGKLDE
CCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCHH
AAKTPGNGKPRLINRALSRLLAELADAHKERARFDKFIRSNTFLDPQTRIGNRLFLQNRL
HHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCHHHHHHH
NALSSDQGMLAPGVLYLLEMEDLDILQQEAGDEVVLELLHSTINAINLVLQTQANSIFAR
HHHCCCCCCCCCCCEEEEEHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RSHNQLAIVVPQISLVEADALADKLLKICLAQPLPKIEEADNFFHLGGAYFKEGDMPEPL
CCCCCEEEEECCHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCEEECCCHHHCCCCCCCHH
LDEADMALRAAQLQGASGWFMYDKGAVDQEFAKGSVRWRSFLENALVNRNFVTFAQPVCE
HHHHHHHHHHHHHCCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHC
GDGSHHHHEIFTRVRDPMGSLVRATLFIPMAVKCGLMPQIERQVVERTLFELMSDTGTAK
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCC
RHYSINLSVDSLTSRAFVRWLQTTLLEYRHLASRLVFEVTEDMVMKHRSQLEPKLNMLRK
EEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
MGSRICVDHVGQQVVSTQYIRELGFNFIKLHRSVVRQIDLRPENQLFVRSLIGSLYRTDV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
QVFAEGVGSFEEWQTLQILGVSAGQGTYFGDPQQI
HHHHHHCCCHHHCCEEEEEEEECCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9278503; 3049542 [H]