Click here to switch to the map view.

The map label for this gene is rstB [H]

Identifier: 119773578

GI number: 119773578

Start: 536704

End: 538971

Strand: Direct

Name: rstB [H]

Synonym: Sama_0438

Alternate gene names: 119773578

Gene position: 536704-538971 (Clockwise)

Preceding gene: 119773577

Following gene: 119773579

Centisome position: 12.46

GC content: 57.63

Gene sequence:

>2268_bases
ATGACGCAGTCATCGGCAGTACCCCACCCTGAAGGACGCCGCTCGCGGTTGGGTGGGATGCCATGGCTGTCGGCGCTCTC
GTCCTGCGTGCCGGCAATGATGCTGGCAATGATGATGGCCTTGTTCCTGTCTGGCTGTGGCGAAAATCAGGCCGGGGCAG
CTGCCAGCACTGAGATAAGCGGTGATGCGAGAGTGCAGGAGCTACTCACGCTCGCTGCCGCTTCCCGCAATGACGATCCC
CACAAAACCATCGACTACAGCAGCCAGGCATTAACGCTGCTGAAAGAAATACCCGAACCCGCCTCGGAAGTGATGGCGCT
CAGCAACCTCGCCTGGGCCAAGATGTTATTGGGAGACTTTACCGAAGCCGCGCAATACGGCGAGGCCGCATTAACGCTGG
CGGAGAATCAACACCAGCCCGAGATGCTGGTGGTGCCCCTCAATGTGACAGGCCTTATTTACTGGCGTCAGAGTCAGCTG
GACAAGGCGCTGACCTATTATCAGCGGGCACTGGAGGTGGCCAAAGGACTCAATAAGCGCTCGTTTGAGGCGACCACCTA
TAACAATATGGGGCTTATCCACAGCGATAAGGCGGAGTATCAACTGGCGCTGGAATGTTTTACCCGGGCGCGGGACATAC
ACCAGGGGCTGGGGGACGAGCGGCCTTTGGCAACGGCGCTGAACAATATTGCCGGTATTCATGCCACCCTCGGAGATTAT
GGTGAGGCGCTGGCCAATCAACAGGCATCGCTGCGGATCCGCGAAAAGTTGGATGATAAGCCCGGCGTTGCCGAGTTGCA
TCACAATATGGGCATTACCTATGAGCAGATAGGGGATTTGAAGGAGTCCATGCTTCAGCTGCAACAGGGGCTGAGAGGAT
TTGAGGCGCTGGGGGATAAAACCGGCATGGCGCAGGCCCTGACAGCCTTGGGTATGGTCAATCAGAAACTGAAAAATGAC
GTCGATGCCAGGATCTCCATGGAGCAGGCACTTGCCTACGGAGAAGAGCTTAATGATGGCAATATCACGGCCACAGCCCT
GATGAGCCTGGGTAAGCTGGCGTTGGCCATGGGGGATGCTCAGGGAGCAAGGCGCTATCTGGAGCGCGGGCTGGCCATTG
CCGATCGCCTGGGACTGGTCGCCTTGCAGGCTCAGGGGCGACTGCGACTTGCGGATTATTTTCTGGTCACCAGCGAGGTG
GATGTGGCGCGGGAGAGGGCGCTGCAGGCACAGCAATTGGCTCTGACCAGCGGCGATCGCAGTCTGCTGAGGGATACCTA
TGAGATCCTTTCTCAAATCTATGAGAGAAAAGGGGATTATCAACAGGCACTTGCCAGCCACAAAGAATTCAAAAGCATTA
ATGATGCCCTTTTCAATGCCAGTTCACAGGATCGCCTTGCCTGGCTTCGCAGCTCCTTTGAGGCAGAAAAACGCCAGCGT
CAGATAACCGAGCTCGAGAGCGAAAAAGCGTTGCAGGCGGAGGTGATAAAACAGCAGCGGGTGGCCCGTAACCTCTGGAT
TTTGGCGTTGATTGCGGTTGCAGCCATCATGCTGCTGCTCTACGGTCGGCACAGTCAGGCCCGGGTTAATCAGGCACTGC
AGCGCTCTATTCAGATGCAGCGGGACTTGATGCAGGCGGTGGCCCATGAATTCAGGGCACCGTTGGCGAGGGTACAACTG
GCTTTCGATATGCTGATGGAAGCCGATGCCAAAGAGCAGCCTCAGTTGGAAGACAGGGTGCTGCGTGGGCTCGAAGAGCT
GGACGAACTTATCCGCGAAATCGTCAAACTTATCAAAGCAGAAGGCAGCCCGCGCCGCGCGCCGAGTGAATCTCTGTCGT
TGGCGCCCCTGCTGCAAACCCTGGTAGCACGCCAGCATCAGCTGTTCCCCGAAAAGCATCTTGAATTGGCGGCAATCGAT
GAGGACTTACGGCTCACCGCCAGTAAGAAACATCTGGAGTGGGCCATCAATAATTTACTCTCCAACGCCCTGCGCTACAG
TCGGGAGCAGGTCCGGGTCAGCTGCCAGCGAGAATCGGAACACCTCTGCATCATTGTGGATGATGACGGGCCGGGTGTAC
CGGCATCTGAGCGGGAGCGTATTTTCGAGCCTTTTGTGCGCCTTGATCCCAGTCGTACCCGGGCCACCGGTGGTATTGGC
CTTGGGCTGGCGATTGCCCGCCGGTTGGCGGAAAACGCCCATGGCCATATCCGGGTTGGCGACAGCCCCCTGGGCGGCGC
CCGTTTCGAGCTTATCTGGCCCTACTGA

Upstream 100 bases:

>100_bases
AGGGTGTCGCACCTGCGCCGCAAAATGGGCGACGATCCCCGTGAGCCAGCACTCATCAAAACCATGCGTGGCCAGGGCTA
CGTACTGACCTTGAATTGAA

Downstream 100 bases:

>100_bases
CGCTTTTGCGCGTTAACCTGCCTGTAATCTTCTTTGTATTCGAAAAAATACACTTATCCCGAACCCCTTATATTTGCTGA
TAAAAAGCGCACTCCGACAG

Product: signal transduction histidine kinase-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 755; Mature: 754

Protein sequence:

>755_residues
MTQSSAVPHPEGRRSRLGGMPWLSALSSCVPAMMLAMMMALFLSGCGENQAGAAASTEISGDARVQELLTLAAASRNDDP
HKTIDYSSQALTLLKEIPEPASEVMALSNLAWAKMLLGDFTEAAQYGEAALTLAENQHQPEMLVVPLNVTGLIYWRQSQL
DKALTYYQRALEVAKGLNKRSFEATTYNNMGLIHSDKAEYQLALECFTRARDIHQGLGDERPLATALNNIAGIHATLGDY
GEALANQQASLRIREKLDDKPGVAELHHNMGITYEQIGDLKESMLQLQQGLRGFEALGDKTGMAQALTALGMVNQKLKND
VDARISMEQALAYGEELNDGNITATALMSLGKLALAMGDAQGARRYLERGLAIADRLGLVALQAQGRLRLADYFLVTSEV
DVARERALQAQQLALTSGDRSLLRDTYEILSQIYERKGDYQQALASHKEFKSINDALFNASSQDRLAWLRSSFEAEKRQR
QITELESEKALQAEVIKQQRVARNLWILALIAVAAIMLLLYGRHSQARVNQALQRSIQMQRDLMQAVAHEFRAPLARVQL
AFDMLMEADAKEQPQLEDRVLRGLEELDELIREIVKLIKAEGSPRRAPSESLSLAPLLQTLVARQHQLFPEKHLELAAID
EDLRLTASKKHLEWAINNLLSNALRYSREQVRVSCQRESEHLCIIVDDDGPGVPASERERIFEPFVRLDPSRTRATGGIG
LGLAIARRLAENAHGHIRVGDSPLGGARFELIWPY

Sequences:

>Translated_755_residues
MTQSSAVPHPEGRRSRLGGMPWLSALSSCVPAMMLAMMMALFLSGCGENQAGAAASTEISGDARVQELLTLAAASRNDDP
HKTIDYSSQALTLLKEIPEPASEVMALSNLAWAKMLLGDFTEAAQYGEAALTLAENQHQPEMLVVPLNVTGLIYWRQSQL
DKALTYYQRALEVAKGLNKRSFEATTYNNMGLIHSDKAEYQLALECFTRARDIHQGLGDERPLATALNNIAGIHATLGDY
GEALANQQASLRIREKLDDKPGVAELHHNMGITYEQIGDLKESMLQLQQGLRGFEALGDKTGMAQALTALGMVNQKLKND
VDARISMEQALAYGEELNDGNITATALMSLGKLALAMGDAQGARRYLERGLAIADRLGLVALQAQGRLRLADYFLVTSEV
DVARERALQAQQLALTSGDRSLLRDTYEILSQIYERKGDYQQALASHKEFKSINDALFNASSQDRLAWLRSSFEAEKRQR
QITELESEKALQAEVIKQQRVARNLWILALIAVAAIMLLLYGRHSQARVNQALQRSIQMQRDLMQAVAHEFRAPLARVQL
AFDMLMEADAKEQPQLEDRVLRGLEELDELIREIVKLIKAEGSPRRAPSESLSLAPLLQTLVARQHQLFPEKHLELAAID
EDLRLTASKKHLEWAINNLLSNALRYSREQVRVSCQRESEHLCIIVDDDGPGVPASERERIFEPFVRLDPSRTRATGGIG
LGLAIARRLAENAHGHIRVGDSPLGGARFELIWPY
>Mature_754_residues
TQSSAVPHPEGRRSRLGGMPWLSALSSCVPAMMLAMMMALFLSGCGENQAGAAASTEISGDARVQELLTLAAASRNDDPH
KTIDYSSQALTLLKEIPEPASEVMALSNLAWAKMLLGDFTEAAQYGEAALTLAENQHQPEMLVVPLNVTGLIYWRQSQLD
KALTYYQRALEVAKGLNKRSFEATTYNNMGLIHSDKAEYQLALECFTRARDIHQGLGDERPLATALNNIAGIHATLGDYG
EALANQQASLRIREKLDDKPGVAELHHNMGITYEQIGDLKESMLQLQQGLRGFEALGDKTGMAQALTALGMVNQKLKNDV
DARISMEQALAYGEELNDGNITATALMSLGKLALAMGDAQGARRYLERGLAIADRLGLVALQAQGRLRLADYFLVTSEVD
VARERALQAQQLALTSGDRSLLRDTYEILSQIYERKGDYQQALASHKEFKSINDALFNASSQDRLAWLRSSFEAEKRQRQ
ITELESEKALQAEVIKQQRVARNLWILALIAVAAIMLLLYGRHSQARVNQALQRSIQMQRDLMQAVAHEFRAPLARVQLA
FDMLMEADAKEQPQLEDRVLRGLEELDELIREIVKLIKAEGSPRRAPSESLSLAPLLQTLVARQHQLFPEKHLELAAIDE
DLRLTASKKHLEWAINNLLSNALRYSREQVRVSCQRESEHLCIIVDDDGPGVPASERERIFEPFVRLDPSRTRATGGIGL
GLAIARRLAENAHGHIRVGDSPLGGARFELIWPY

Specific function: Member of the two-component regulatory system rstB/rstA. RstB functions as a membrane-associated protein kinase that phosphorylates rstA (Potential) [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Homo sapiens, GI224028289, Length=398, Percent_Identity=27.8894472361809, Blast_Score=102, Evalue=1e-21,
Organism=Homo sapiens, GI164519122, Length=302, Percent_Identity=24.5033112582781, Blast_Score=68, Evalue=3e-11,
Organism=Escherichia coli, GI1787894, Length=223, Percent_Identity=36.322869955157, Blast_Score=130, Evalue=4e-31,
Organism=Escherichia coli, GI1790346, Length=227, Percent_Identity=34.3612334801762, Blast_Score=113, Evalue=4e-26,
Organism=Escherichia coli, GI1789808, Length=204, Percent_Identity=30.8823529411765, Blast_Score=105, Evalue=1e-23,
Organism=Escherichia coli, GI1787374, Length=141, Percent_Identity=37.5886524822695, Blast_Score=97, Evalue=3e-21,
Organism=Escherichia coli, GI1786600, Length=262, Percent_Identity=27.0992366412214, Blast_Score=96, Evalue=8e-21,
Organism=Escherichia coli, GI1788393, Length=229, Percent_Identity=29.2576419213974, Blast_Score=93, Evalue=6e-20,
Organism=Escherichia coli, GI145693157, Length=272, Percent_Identity=27.5735294117647, Blast_Score=88, Evalue=2e-18,
Organism=Escherichia coli, GI1786783, Length=242, Percent_Identity=27.6859504132231, Blast_Score=86, Evalue=1e-17,
Organism=Escherichia coli, GI1788549, Length=220, Percent_Identity=29.0909090909091, Blast_Score=79, Evalue=1e-15,
Organism=Escherichia coli, GI87081816, Length=241, Percent_Identity=29.045643153527, Blast_Score=75, Evalue=2e-14,
Organism=Escherichia coli, GI48994928, Length=253, Percent_Identity=27.6679841897233, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI87082128, Length=211, Percent_Identity=32.2274881516588, Blast_Score=67, Evalue=4e-12,
Organism=Escherichia coli, GI1786912, Length=280, Percent_Identity=27.1428571428571, Blast_Score=67, Evalue=4e-12,
Organism=Escherichia coli, GI1790861, Length=207, Percent_Identity=27.536231884058, Blast_Score=64, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24660950, Length=293, Percent_Identity=24.9146757679181, Blast_Score=75, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 83689; Mature: 83558

Theoretical pI: Translated: 6.10; Mature: 6.10

Prosite motif: PS50005 TPR L=RR ; PS50293 TPR_REGION ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQSSAVPHPEGRRSRLGGMPWLSALSSCVPAMMLAMMMALFLSGCGENQAGAAASTEIS
CCCCCCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
GDARVQELLTLAAASRNDDPHKTIDYSSQALTLLKEIPEPASEVMALSNLAWAKMLLGDF
CHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
TEAAQYGEAALTLAENQHQPEMLVVPLNVTGLIYWRQSQLDKALTYYQRALEVAKGLNKR
HHHHHHCCHHEEECCCCCCCCEEEEEECCEEEEEECHHHHHHHHHHHHHHHHHHHCCCCC
SFEATTYNNMGLIHSDKAEYQLALECFTRARDIHQGLGDERPLATALNNIAGIHATLGDY
CCCCCCCCCCCCEECCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHH
GEALANQQASLRIREKLDDKPGVAELHHNMGITYEQIGDLKESMLQLQQGLRGFEALGDK
HHHHHCCHHHHHHHHHCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCC
TGMAQALTALGMVNQKLKNDVDARISMEQALAYGEELNDGNITATALMSLGKLALAMGDA
CHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCH
QGARRYLERGLAIADRLGLVALQAQGRLRLADYFLVTSEVDVARERALQAQQLALTSGDR
HHHHHHHHHHHHHHHHHCEEEEECCCCEEEHHHHEEECHHHHHHHHHHHHHHHHHCCCCH
SLLRDTYEILSQIYERKGDYQQALASHKEFKSINDALFNASSQDRLAWLRSSFEAEKRQR
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
QITELESEKALQAEVIKQQRVARNLWILALIAVAAIMLLLYGRHSQARVNQALQRSIQMQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
RDLMQAVAHEFRAPLARVQLAFDMLMEADAKEQPQLEDRVLRGLEELDELIREIVKLIKA
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHC
EGSPRRAPSESLSLAPLLQTLVARQHQLFPEKHLELAAIDEDLRLTASKKHLEWAINNLL
CCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHCCCHHCCCCHHHHHHHHHHHHHHHHHHH
SNALRYSREQVRVSCQRESEHLCIIVDDDGPGVPASERERIFEPFVRLDPSRTRATGGIG
HHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHCCCCHHHCCCCCH
LGLAIARRLAENAHGHIRVGDSPLGGARFELIWPY
HHHHHHHHHHHCCCCEEEECCCCCCCCEEEEECCC
>Mature Secondary Structure 
TQSSAVPHPEGRRSRLGGMPWLSALSSCVPAMMLAMMMALFLSGCGENQAGAAASTEIS
CCCCCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
GDARVQELLTLAAASRNDDPHKTIDYSSQALTLLKEIPEPASEVMALSNLAWAKMLLGDF
CHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
TEAAQYGEAALTLAENQHQPEMLVVPLNVTGLIYWRQSQLDKALTYYQRALEVAKGLNKR
HHHHHHCCHHEEECCCCCCCCEEEEEECCEEEEEECHHHHHHHHHHHHHHHHHHHCCCCC
SFEATTYNNMGLIHSDKAEYQLALECFTRARDIHQGLGDERPLATALNNIAGIHATLGDY
CCCCCCCCCCCCEECCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHH
GEALANQQASLRIREKLDDKPGVAELHHNMGITYEQIGDLKESMLQLQQGLRGFEALGDK
HHHHHCCHHHHHHHHHCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCC
TGMAQALTALGMVNQKLKNDVDARISMEQALAYGEELNDGNITATALMSLGKLALAMGDA
CHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCH
QGARRYLERGLAIADRLGLVALQAQGRLRLADYFLVTSEVDVARERALQAQQLALTSGDR
HHHHHHHHHHHHHHHHHCEEEEECCCCEEEHHHHEEECHHHHHHHHHHHHHHHHHCCCCH
SLLRDTYEILSQIYERKGDYQQALASHKEFKSINDALFNASSQDRLAWLRSSFEAEKRQR
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
QITELESEKALQAEVIKQQRVARNLWILALIAVAAIMLLLYGRHSQARVNQALQRSIQMQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
RDLMQAVAHEFRAPLARVQLAFDMLMEADAKEQPQLEDRVLRGLEELDELIREIVKLIKA
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHC
EGSPRRAPSESLSLAPLLQTLVARQHQLFPEKHLELAAIDEDLRLTASKKHLEWAINNLL
CCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHCCCHHCCCCHHHHHHHHHHHHHHHHHHH
SNALRYSREQVRVSCQRESEHLCIIVDDDGPGVPASERERIFEPFVRLDPSRTRATGGIG
HHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHCCCCHHHCCCCCH
LGLAIARRLAENAHGHIRVGDSPLGGARFELIWPY
HHHHHHHHHHHCCCCEEEECCCCCCCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503; 2646639; 1925016; 1495392 [H]