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The map label for this gene is ubiA

Identifier: 119773560

GI number: 119773560

Start: 517977

End: 518849

Strand: Direct

Name: ubiA

Synonym: Sama_0420

Alternate gene names: 119773560

Gene position: 517977-518849 (Clockwise)

Preceding gene: 119773559

Following gene: 119773563

Centisome position: 12.03

GC content: 56.47

Gene sequence:

>873_bases
ATGAGCAAAATGGCGCAAAAATGGGATGCCTATTACCGATTGATGCGACTCGACAGACCCATAGGCACCATGCTGCTGCT
GTGGCCCTGCCTGATGGCACTGCTGCTGGCCGCTGACGGAATGCCCGACTTACGGGTGCTTATCATCTTCATCATTGGAG
TGGTGGTGATGCGCGCCTGTGGTTGCATCATCAACGACTACGCCGACCGCAAGCTCGATTCCCATGTGGCCCGTACCCGG
TCGCGGCCTCTGGCCAGCGGTGAGGTCACGGTTGCCGAGGCCCTCACCCTGTTTGTGGTGTTGGGGTTGTTCGCCTTTTC
GTTGGTGTTGTTGCTCAACCCTCTGGTGGTGCAGCTCTCGGTGGTGGGCATTATTCTGACCATCATTTATCCCTTTACCA
AACGCTGGACCAATATGCCGCAGATGTTTTTGGGGGTGGTGTGGAGCTGGTCCATTCCCATGGCCTATGCGGCACAAACC
GGTGAAGTGCCTGCCTCTGCCTGGTGGCTCTTTGCGGCCAACTGGTGCTGGACAGTGGCCTACGACACCATGTATGCCAT
GGTTGACCGGGATGACGACCTCAAGGTGGGGATTAAGTCCACCGCGATTTTATTTGGTCGCTTTGACCGTGAAATTATAG
GCGCGTTTCAGCTTGCGGCCCTGGGCTGCTTTATCGCGGCGGGCTGGAGTGGCGATCGCGGCCTGCTGTATGGTCTGGGT
GTGCTGACCTTTGTGGGCTTTTCTGCCTATCAACAACGGCTCATTTATGGCCGTGAACGGGGCGATTGTTTCAAGGCTTT
TTTAAACAACAACTGGGCCGGGCTCAGTCTGTTTTTGGCGCTTGGAGCTGACTACGCCTTTGCAGCGCTGTAG

Upstream 100 bases:

>100_bases
GCCAAGCTGGAATCCCTGTGAGCCCAAGGGCAAAGATGCCAGAGCAAAACACAAAAGATAACAACCGCGCGATGACCCCA
AATGGGGACAAGGAAAGACA

Downstream 100 bases:

>100_bases
CGCCGCCGATGGGGGAGAGATCCTGATGGATCATCCACTGATGTTCCGGCGGCAGTGTCAGACTTAAATCTGCCGCTGCC
AGATTTTCACTGGTCAGTAC

Product: 4-hydroxybenzoate octaprenyltransferase

Products: NA

Alternate protein names: 4-HB polyprenyltransferase

Number of amino acids: Translated: 290; Mature: 289

Protein sequence:

>290_residues
MSKMAQKWDAYYRLMRLDRPIGTMLLLWPCLMALLLAADGMPDLRVLIIFIIGVVVMRACGCIINDYADRKLDSHVARTR
SRPLASGEVTVAEALTLFVVLGLFAFSLVLLLNPLVVQLSVVGIILTIIYPFTKRWTNMPQMFLGVVWSWSIPMAYAAQT
GEVPASAWWLFAANWCWTVAYDTMYAMVDRDDDLKVGIKSTAILFGRFDREIIGAFQLAALGCFIAAGWSGDRGLLYGLG
VLTFVGFSAYQQRLIYGRERGDCFKAFLNNNWAGLSLFLALGADYAFAAL

Sequences:

>Translated_290_residues
MSKMAQKWDAYYRLMRLDRPIGTMLLLWPCLMALLLAADGMPDLRVLIIFIIGVVVMRACGCIINDYADRKLDSHVARTR
SRPLASGEVTVAEALTLFVVLGLFAFSLVLLLNPLVVQLSVVGIILTIIYPFTKRWTNMPQMFLGVVWSWSIPMAYAAQT
GEVPASAWWLFAANWCWTVAYDTMYAMVDRDDDLKVGIKSTAILFGRFDREIIGAFQLAALGCFIAAGWSGDRGLLYGLG
VLTFVGFSAYQQRLIYGRERGDCFKAFLNNNWAGLSLFLALGADYAFAAL
>Mature_289_residues
SKMAQKWDAYYRLMRLDRPIGTMLLLWPCLMALLLAADGMPDLRVLIIFIIGVVVMRACGCIINDYADRKLDSHVARTRS
RPLASGEVTVAEALTLFVVLGLFAFSLVLLLNPLVVQLSVVGIILTIIYPFTKRWTNMPQMFLGVVWSWSIPMAYAAQTG
EVPASAWWLFAANWCWTVAYDTMYAMVDRDDDLKVGIKSTAILFGRFDREIIGAFQLAALGCFIAAGWSGDRGLLYGLGV
LTFVGFSAYQQRLIYGRERGDCFKAFLNNNWAGLSLFLALGADYAFAAL

Specific function: Synthesis of 3-octaprenyl-4-hydroxybenzoate

COG id: COG0382

COG function: function code H; 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ubiA prenyltransferase family

Homologues:

Organism=Homo sapiens, GI260656052, Length=280, Percent_Identity=35.3571428571429, Blast_Score=152, Evalue=2e-37,
Organism=Escherichia coli, GI1790473, Length=276, Percent_Identity=54.3478260869565, Blast_Score=287, Evalue=6e-79,
Organism=Escherichia coli, GI1786631, Length=161, Percent_Identity=29.1925465838509, Blast_Score=65, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17553718, Length=271, Percent_Identity=34.6863468634686, Blast_Score=163, Evalue=1e-40,
Organism=Caenorhabditis elegans, GI32565247, Length=277, Percent_Identity=33.5740072202166, Blast_Score=147, Evalue=7e-36,
Organism=Caenorhabditis elegans, GI17553720, Length=185, Percent_Identity=37.2972972972973, Blast_Score=107, Evalue=9e-24,
Organism=Caenorhabditis elegans, GI32565245, Length=139, Percent_Identity=39.568345323741, Blast_Score=95, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI32565243, Length=136, Percent_Identity=39.7058823529412, Blast_Score=92, Evalue=3e-19,
Organism=Saccharomyces cerevisiae, GI6324370, Length=294, Percent_Identity=32.9931972789116, Blast_Score=146, Evalue=4e-36,
Organism=Drosophila melanogaster, GI21355567, Length=277, Percent_Identity=38.9891696750903, Blast_Score=181, Evalue=5e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): UBIA_SHEAM (A1S2M4)

Other databases:

- EMBL:   CP000507
- RefSeq:   YP_926300.1
- STRING:   A1S2M4
- GeneID:   4602675
- GenomeReviews:   CP000507_GR
- KEGG:   saz:Sama_0420
- NMPDR:   fig|326297.7.peg.398
- eggNOG:   COG0382
- HOGENOM:   HBG324383
- OMA:   YHYTLIR
- PhylomeDB:   A1S2M4
- ProtClustDB:   PRK12848
- HAMAP:   MF_01635
- InterPro:   IPR006370
- InterPro:   IPR000537
- TIGRFAMs:   TIGR01474

Pfam domain/function: PF01040 UbiA

EC number: 2.5.1.-

Molecular weight: Translated: 32306; Mature: 32174

Theoretical pI: Translated: 8.34; Mature: 8.34

Prosite motif: PS00943 UBIA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x10a06ebc)-; HASH(0x110afe94)-; HASH(0x119d84b8)-; HASH(0x10c2f7d0)-; HASH(0x11ad89b8)-; HASH(0x10d76794)-; HASH(0x1187783c)-; HASH(0x1001cf50)-;

Cys/Met content:

2.1 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCHHHHHHHHHCCCHHHHCH
>Mature Secondary Structure 
SKMAQKWDAYYRLMRLDRPIGTMLLLWPCLMALLLAADGMPDLRVLIIFIIGVVVMRAC
CHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
GCIINDYADRKLDSHVARTRSRPLASGEVTVAEALTLFVVLGLFAFSLVLLLNPLVVQLS
HHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VVGIILTIIYPFTKRWTNMPQMFLGVVWSWSIPMAYAAQTGEVPASAWWLFAANWCWTVA
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHCCCCCCCHHHHHHHHHHHHHHHH
YDTMYAMVDRDDDLKVGIKSTAILFGRFDREIIGAFQLAALGCFIAAGWSGDRGLLYGLG
HHHHHHHHCCCCCCEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHH
VLTFVGFSAYQQRLIYGRERGDCFKAFLNNNWAGLSLFLALGADYAFAAL
HHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCHHHHHHHHHCCCHHHHCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA