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The map label for this gene is ftsW [H]

Identifier: 119773494

GI number: 119773494

Start: 423163

End: 424371

Strand: Direct

Name: ftsW [H]

Synonym: Sama_0353

Alternate gene names: 119773494

Gene position: 423163-424371 (Clockwise)

Preceding gene: 119773493

Following gene: 119773495

Centisome position: 9.83

GC content: 54.84

Gene sequence:

>1209_bases
ATGGCAACTGACAGCAAACAGCTCACCCTGTTTGAGCGTAGCGGCCATTTCTGGACCAGCTGGCTAAGCGGACGCAGTGC
GCCCGGCAACCAGCTGTATGACCGTGCGCTGCTGTCTGTTGTGTTGGGATTGATGGGATTTGGCTTTGTGATGGTGATGT
CGGCCTCCATGCCCGAAGCCCAGAGTTTGAAGGACGACCCCTTCCACTTTATGTACCGCCATGTGTTTTATCTGGTGGGT
TGTGTGGCGATTGCCACTGTGGTGCTGCGTATCCCCATGGCGAGCTGGCAAAAATACAGCCCCTTGTTATTGCTGGGGGT
CTTTGTGCTGCTTATCGCCGTGCTGGTGGTGGGCACTACCGTGAATGGTGCCAGGCGTTGGCTCAGCGTGGGCCCGATAC
GCATTCAGGTAGCCGAAATGGCCAAACTGGTATTTGCCATTTACCTGTCGGGCTACCTAGTGCGCAGGCTCCAGGAAGTG
CGTGAAAATGCCAAGGGGTTTTATAAGCCCATCGCCGTGTTTGCGCTTTATGCACTCTTGATCCTGGCCCAGCCGGATCT
GGGCACTGTGGTGGTGCTTTTTGTGGGCACAGTTGGCCTGCTGTTCCTGGCCGGCGCCAGGCTGCTCGACTTTTTTATGT
TGATTTTTGCCGGCGTGATGGCCTTCGTCGCTCTGGTTGTGCTCGAGCCTTACCGTGTTGCCCGGGTGACATCTTTCCTT
AATCCCTGGGAAGATCCCTTCGGCAGCGGTTACCAGCTCACTCAGTCACTGATGGCCTATGGTCGGGGTGACTGGCTGGG
GCAGGGACTGGGCAACAGTATTCAGAAACTGGAATATCTGCCTGAGGCCCATACCGACTTTATTTTTGCCGTAATCGGTG
AAGAGCTGGGATTTATCGGCATTGTAATGGTATTGCTGGCGTTGATGTTTGTGGCACTGCGCGCCATCCGGTTGGGTAAC
GAGTGTTTGGGGCTTGAGCGTGCCTTTGAAGGCTACCTCGCCTATGCCATCGGTATTTGGATTTGTTTCCAAACCGTGGT
GAATGTGGGGGCCAGTATCGGCATGTTGCCCACCAAGGGACTGACGCTGCCGTTTATCAGTTACGGCGGCTCCAGTTTGT
GGGTAATGACCTCGGCTGTGTGTATTTTGCTTCGCATCGATTATGAAAAACGCCTGAGTCAGATTCAGGCCGTACAGGGG
AGACTCTAA

Upstream 100 bases:

>100_bases
GGTGACATTGTGCTCTTGTCTCCAGCCTGCGCCAGCCTGGACATGTACACCAACTTTATGGCCCGAGGGGATGATTTCAG
GGCCAATGTGGAGCGGGTCT

Downstream 100 bases:

>100_bases
ATGGGCCCACAGACAGGCAAAAGACTCTTGGTGATGGCCGGTGGCACCGGTGGTCACGTCTTTCCTGCACTGGCGGTGGC
CCGACGTCTCGCCAGTGAAG

Product: cell division protein FtsW

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 402; Mature: 401

Protein sequence:

>402_residues
MATDSKQLTLFERSGHFWTSWLSGRSAPGNQLYDRALLSVVLGLMGFGFVMVMSASMPEAQSLKDDPFHFMYRHVFYLVG
CVAIATVVLRIPMASWQKYSPLLLLGVFVLLIAVLVVGTTVNGARRWLSVGPIRIQVAEMAKLVFAIYLSGYLVRRLQEV
RENAKGFYKPIAVFALYALLILAQPDLGTVVVLFVGTVGLLFLAGARLLDFFMLIFAGVMAFVALVVLEPYRVARVTSFL
NPWEDPFGSGYQLTQSLMAYGRGDWLGQGLGNSIQKLEYLPEAHTDFIFAVIGEELGFIGIVMVLLALMFVALRAIRLGN
ECLGLERAFEGYLAYAIGIWICFQTVVNVGASIGMLPTKGLTLPFISYGGSSLWVMTSAVCILLRIDYEKRLSQIQAVQG
RL

Sequences:

>Translated_402_residues
MATDSKQLTLFERSGHFWTSWLSGRSAPGNQLYDRALLSVVLGLMGFGFVMVMSASMPEAQSLKDDPFHFMYRHVFYLVG
CVAIATVVLRIPMASWQKYSPLLLLGVFVLLIAVLVVGTTVNGARRWLSVGPIRIQVAEMAKLVFAIYLSGYLVRRLQEV
RENAKGFYKPIAVFALYALLILAQPDLGTVVVLFVGTVGLLFLAGARLLDFFMLIFAGVMAFVALVVLEPYRVARVTSFL
NPWEDPFGSGYQLTQSLMAYGRGDWLGQGLGNSIQKLEYLPEAHTDFIFAVIGEELGFIGIVMVLLALMFVALRAIRLGN
ECLGLERAFEGYLAYAIGIWICFQTVVNVGASIGMLPTKGLTLPFISYGGSSLWVMTSAVCILLRIDYEKRLSQIQAVQG
RL
>Mature_401_residues
ATDSKQLTLFERSGHFWTSWLSGRSAPGNQLYDRALLSVVLGLMGFGFVMVMSASMPEAQSLKDDPFHFMYRHVFYLVGC
VAIATVVLRIPMASWQKYSPLLLLGVFVLLIAVLVVGTTVNGARRWLSVGPIRIQVAEMAKLVFAIYLSGYLVRRLQEVR
ENAKGFYKPIAVFALYALLILAQPDLGTVVVLFVGTVGLLFLAGARLLDFFMLIFAGVMAFVALVVLEPYRVARVTSFLN
PWEDPFGSGYQLTQSLMAYGRGDWLGQGLGNSIQKLEYLPEAHTDFIFAVIGEELGFIGIVMVLLALMFVALRAIRLGNE
CLGLERAFEGYLAYAIGIWICFQTVVNVGASIGMLPTKGLTLPFISYGGSSLWVMTSAVCILLRIDYEKRLSQIQAVQGR
L

Specific function: This is a septum-peptidoglycan biosynthetic protein, involved in cell wall formation. Plays a role in the stabilization of the ftsZ ring during cell division [H]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786277, Length=366, Percent_Identity=59.5628415300546, Blast_Score=435, Evalue=1e-123,
Organism=Escherichia coli, GI1786853, Length=325, Percent_Identity=31.0769230769231, Blast_Score=146, Evalue=2e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365
- InterPro:   IPR013437 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 44391; Mature: 44260

Theoretical pI: Translated: 8.99; Mature: 8.99

Prosite motif: PS00012 PHOSPHOPANTETHEINE ; PS00428 FTSW_RODA_SPOVE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCCCHHHCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCC
>Mature Secondary Structure 
ATDSKQLTLFERSGHFWTSWLSGRSAPGNQLYDRALLSVVLGLMGFGFVMVMSASMPEA
CCCCCCEEEEECCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCH
QSLKDDPFHFMYRHVFYLVGCVAIATVVLRIPMASWQKYSPLLLLGVFVLLIAVLVVGTT
HCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHCCCHHHHHHHHHHHHHHHHHCCC
VNGARRWLSVGPIRIQVAEMAKLVFAIYLSGYLVRRLQEVRENAKGFYKPIAVFALYALL
CHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ILAQPDLGTVVVLFVGTVGLLFLAGARLLDFFMLIFAGVMAFVALVVLEPYRVARVTSFL
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
NPWEDPFGSGYQLTQSLMAYGRGDWLGQGLGNSIQKLEYLPEAHTDFIFAVIGEELGFIG
CCCCCCCCCCHHHHHHHHHHCCCCHHHHHCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
IVMVLLALMFVALRAIRLGNECLGLERAFEGYLAYAIGIWICFQTVVNVGASIGMLPTKG
HHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
LTLPFISYGGSSLWVMTSAVCILLRIDYEKRLSQIQAVQGRL
CCCCHHHCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]