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The map label for this gene is fadL [H]

Identifier: 119773480

GI number: 119773480

Start: 408539

End: 409897

Strand: Direct

Name: fadL [H]

Synonym: Sama_0339

Alternate gene names: 119773480

Gene position: 408539-409897 (Clockwise)

Preceding gene: 119773479

Following gene: 119773481

Centisome position: 9.49

GC content: 56.59

Gene sequence:

>1359_bases
ATGATAATGAAAAAGAGTGTACTGACTTTTGCCGTATCAGCGGCTCTTATGGGGATTACGACTCAGGTTAACGCTGCTGG
CTTCCAGCTGGCTGAATACTCTGCCACTGGTCTTGGCCGTGCTTTTGCCGGTGAAGCGGCCATGGCCGACAACGCCGCGG
CTCAAGCGCGTAACCCAGCCATGCTGGCATACCTGAGCGGTCGTCAGGTATCCGGCGGCGGTATCTACGTCGCTACCGAA
GTGGACGTGACCGGCGATGTGCACATTGCGTCTCCAGTGCTTGGTCCGCAGGGTGTGACGCTGAATGCCGACGCCTATGA
CGTTGCCGACAGTGCACTTATCCCAAACTTCTATTACTCAAGCCAAATCAATGACAACTGGACCTGGGGTCTGGCTGTTA
ACTCCAACTACGGCCTGGCCACCGAGCTGCCTGCCACTCACGCGGCCTCCTTGTTTGGCCATCACACCGAAATCACCACA
GTTGAGTTCAACCCCAACATCGCATATCGCCTGAACGATGCGGTGACTTTGGGTGCCGGTGTGCGCATTGTTTACGGTGA
CGGTAGCATTGGTGCAGCTACACCTTACTGGGTGGGCGCCATCAAGGCCAATCCAAACCTGCCAGCACAAATTGCCGCCC
GTCTGCCTGAGCCTGGCACTGTGCTCAAAACCATGGAAGGCGATGATGTAAGCTACGGCTGGCAAGTGGGCGGTAGCTGG
CAGCCTTCTGAAAACCACAGATTCGGCTTGGCTTATCACAGCGGTGTAGAGCTGGAGCTGTCCGGGAGCGCTGCTGGTCT
TGTCTACACTGGTGGCCAGAACCTGGATATTGAAGGTTATCTGCCACTGGAGCTGCCAGCTTTTGCCGAGTTGTCTTCTT
TCCATCAGCTGAGTGATGATGTGGCGCTGCACGCCAGCGTTAACTGGACCCAGTGGAGTGTGTTCGACCGTCTGGTGGCT
TACTTCCCCGGTGAAACCAAGCCAGTGGGTGGCATCGAGTCCGATCTGGTGAAAGAAGAGAACTTCAAGGACAGCTGGCG
CGTTGCCGTAGGTTCTACCTGGAACGTAAACAAAGACTGGACCGTACGCAGCGGCTTTGCGGTTGACCGCACTGCAGTGG
ATGATGAGTTCCGTACCACCACCATCCCCGACTCTGACCGCCTGTGGTTCAGTCTGGGTGCCGGTTACCGCGCCAGCGAA
AACCTGACCGTGGATATGGCCATCACCTATATTCGTGCCCACGGTTTCGCGCCTATCGATGAGCATCAGGATCTGGCCGG
TCTGGCTCAGGTCAGCTTTAACGGTGAAGCCGGTGGCAGCGTGTGGCTGGCCGGTGTGCAGTTAAGCTATAAGATGTAA

Upstream 100 bases:

>100_bases
GTTTTGGTTGCAAAGATATTCTGTATGAATACACTGCCATGCACTTGTTTCGAGTGAATGCTCTATTCGTCGAACGCAAA
ATCAATAACATCAGCAGAGA

Downstream 100 bases:

>100_bases
TTGCATGTTTGAAAAAAGCCCCGCCCATGCGGGGCTTTTGCTTGCGCCAATATCTTGTATAGTGTTGCTTTTGTGACAGT
GTGTTTACGCTGCCTACAGG

Product: aromatic hydrocarbon degradation membrane protein

Products: NA

Alternate protein names: Outer membrane fadL protein; Outer membrane flp protein [H]

Number of amino acids: Translated: 452; Mature: 452

Protein sequence:

>452_residues
MIMKKSVLTFAVSAALMGITTQVNAAGFQLAEYSATGLGRAFAGEAAMADNAAAQARNPAMLAYLSGRQVSGGGIYVATE
VDVTGDVHIASPVLGPQGVTLNADAYDVADSALIPNFYYSSQINDNWTWGLAVNSNYGLATELPATHAASLFGHHTEITT
VEFNPNIAYRLNDAVTLGAGVRIVYGDGSIGAATPYWVGAIKANPNLPAQIAARLPEPGTVLKTMEGDDVSYGWQVGGSW
QPSENHRFGLAYHSGVELELSGSAAGLVYTGGQNLDIEGYLPLELPAFAELSSFHQLSDDVALHASVNWTQWSVFDRLVA
YFPGETKPVGGIESDLVKEENFKDSWRVAVGSTWNVNKDWTVRSGFAVDRTAVDDEFRTTTIPDSDRLWFSLGAGYRASE
NLTVDMAITYIRAHGFAPIDEHQDLAGLAQVSFNGEAGGSVWLAGVQLSYKM

Sequences:

>Translated_452_residues
MIMKKSVLTFAVSAALMGITTQVNAAGFQLAEYSATGLGRAFAGEAAMADNAAAQARNPAMLAYLSGRQVSGGGIYVATE
VDVTGDVHIASPVLGPQGVTLNADAYDVADSALIPNFYYSSQINDNWTWGLAVNSNYGLATELPATHAASLFGHHTEITT
VEFNPNIAYRLNDAVTLGAGVRIVYGDGSIGAATPYWVGAIKANPNLPAQIAARLPEPGTVLKTMEGDDVSYGWQVGGSW
QPSENHRFGLAYHSGVELELSGSAAGLVYTGGQNLDIEGYLPLELPAFAELSSFHQLSDDVALHASVNWTQWSVFDRLVA
YFPGETKPVGGIESDLVKEENFKDSWRVAVGSTWNVNKDWTVRSGFAVDRTAVDDEFRTTTIPDSDRLWFSLGAGYRASE
NLTVDMAITYIRAHGFAPIDEHQDLAGLAQVSFNGEAGGSVWLAGVQLSYKM
>Mature_452_residues
MIMKKSVLTFAVSAALMGITTQVNAAGFQLAEYSATGLGRAFAGEAAMADNAAAQARNPAMLAYLSGRQVSGGGIYVATE
VDVTGDVHIASPVLGPQGVTLNADAYDVADSALIPNFYYSSQINDNWTWGLAVNSNYGLATELPATHAASLFGHHTEITT
VEFNPNIAYRLNDAVTLGAGVRIVYGDGSIGAATPYWVGAIKANPNLPAQIAARLPEPGTVLKTMEGDDVSYGWQVGGSW
QPSENHRFGLAYHSGVELELSGSAAGLVYTGGQNLDIEGYLPLELPAFAELSSFHQLSDDVALHASVNWTQWSVFDRLVA
YFPGETKPVGGIESDLVKEENFKDSWRVAVGSTWNVNKDWTVRSGFAVDRTAVDDEFRTTTIPDSDRLWFSLGAGYRASE
NLTVDMAITYIRAHGFAPIDEHQDLAGLAQVSFNGEAGGSVWLAGVQLSYKM

Specific function: Involved in translocation of long-chain fatty acids across the outer membrane. FadL may form a specific channel [H]

COG id: COG2067

COG function: function code I; Long-chain fatty acid transport protein

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ompP1/fadL family [H]

Homologues:

Organism=Escherichia coli, GI145693163, Length=471, Percent_Identity=31.2101910828025, Blast_Score=231, Evalue=6e-62,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011250
- InterPro:   IPR005017 [H]

Pfam domain/function: PF03349 Toluene_X [H]

EC number: NA

Molecular weight: Translated: 48249; Mature: 48249

Theoretical pI: Translated: 4.38; Mature: 4.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIMKKSVLTFAVSAALMGITTQVNAAGFQLAEYSATGLGRAFAGEAAMADNAAAQARNPA
CCCCHHHHHHHHHHHHHHEEEEECCCCEEEEECCCCCCCCHHCCCCHHCCCCHHHCCCCE
MLAYLSGRQVSGGGIYVATEVDVTGDVHIASPVLGPQGVTLNADAYDVADSALIPNFYYS
EEEEEECCEECCCEEEEEEEEECCCCEEEECCCCCCCCEEECCCHHHCCCCCCCCCEEEC
SQINDNWTWGLAVNSNYGLATELPATHAASLFGHHTEITTVEFNPNIAYRLNDAVTLGAG
CCCCCCEEEEEEEECCCCEEECCCCHHHHHHHCCCEEEEEEEECCCEEEEECCEEEECCC
VRIVYGDGSIGAATPYWVGAIKANPNLPAQIAARLPEPGTVLKTMEGDDVSYGWQVGGSW
EEEEECCCCCCCCCCEEEEEEECCCCCCHHHHHCCCCCCCEEEEECCCCCEECEEECCCC
QPSENHRFGLAYHSGVELELSGSAAGLVYTGGQNLDIEGYLPLELPAFAELSSFHQLSDD
CCCCCCEEEEEEECCEEEEECCCCEEEEEECCCCEEEEEEECCCCCCHHHHHHHHHCCCC
VALHASVNWTQWSVFDRLVAYFPGETKPVGGIESDLVKEENFKDSWRVAVGSTWNVNKDW
EEEEEECCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHCCCCCCCCEEEEECCEECCCCCE
TVRSGFAVDRTAVDDEFRTTTIPDSDRLWFSLGAGYRASENLTVDMAITYIRAHGFAPID
EEECCCEECCCCCCCCCEEEECCCCCCEEEEECCCCCCCCCEEEEEEEEEEECCCCCCCC
EHQDLAGLAQVSFNGEAGGSVWLAGVQLSYKM
CCCCCCEEEEEEECCCCCCEEEEEEEEEEECC
>Mature Secondary Structure
MIMKKSVLTFAVSAALMGITTQVNAAGFQLAEYSATGLGRAFAGEAAMADNAAAQARNPA
CCCCHHHHHHHHHHHHHHEEEEECCCCEEEEECCCCCCCCHHCCCCHHCCCCHHHCCCCE
MLAYLSGRQVSGGGIYVATEVDVTGDVHIASPVLGPQGVTLNADAYDVADSALIPNFYYS
EEEEEECCEECCCEEEEEEEEECCCCEEEECCCCCCCCEEECCCHHHCCCCCCCCCEEEC
SQINDNWTWGLAVNSNYGLATELPATHAASLFGHHTEITTVEFNPNIAYRLNDAVTLGAG
CCCCCCEEEEEEEECCCCEEECCCCHHHHHHHCCCEEEEEEEECCCEEEEECCEEEECCC
VRIVYGDGSIGAATPYWVGAIKANPNLPAQIAARLPEPGTVLKTMEGDDVSYGWQVGGSW
EEEEECCCCCCCCCCEEEEEEECCCCCCHHHHHCCCCCCCEEEEECCCCCEECEEECCCC
QPSENHRFGLAYHSGVELELSGSAAGLVYTGGQNLDIEGYLPLELPAFAELSSFHQLSDD
CCCCCCEEEEEEECCEEEEECCCCEEEEEECCCCEEEEEEECCCCCCHHHHHHHHHCCCC
VALHASVNWTQWSVFDRLVAYFPGETKPVGGIESDLVKEENFKDSWRVAVGSTWNVNKDW
EEEEEECCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHCCCCCCCCEEEEECCEECCCCCE
TVRSGFAVDRTAVDDEFRTTTIPDSDRLWFSLGAGYRASENLTVDMAITYIRAHGFAPID
EEECCCEECCCCCCCCCEEEECCCCCCEEEEECCCCCCCCCEEEEEEEEEEECCCCCCCC
EHQDLAGLAQVSFNGEAGGSVWLAGVQLSYKM
CCCCCCEEEEEEECCCCCCEEEEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]