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The map label for this gene is recQ [H]

Identifier: 119773474

GI number: 119773474

Start: 399235

End: 401058

Strand: Direct

Name: recQ [H]

Synonym: Sama_0333

Alternate gene names: 119773474

Gene position: 399235-401058 (Clockwise)

Preceding gene: 119773472

Following gene: 119773476

Centisome position: 9.27

GC content: 54.61

Gene sequence:

>1824_bases
ATGGAACAACCAGCATCAGAACACACCCAGGATCCTCTGAGCCATTGCCTGCAACAGGTATTTGGTTATCGGGATTTCAG
GCCCGGCCAGCGGGAGGTGATGACGCGGGTGTGTCAGGGTGAAGATTGCCTGGTGATCATGCCCACCGGCGGCGGCAAGA
GCCTTTGTTATCAGGTGCCCGCATTGGTGTTACCCGGTGTAACACTGGTGGTATCGCCGCTGATTTCCCTGATGAAAGAT
CAGGTCGATAGCCTCATTCAGTCCGGTGTTGCTGCTGCGTATCTCAATTCCTCCCAGCCCCGCGAGCAGGCTATAGAGGT
GCTGCGCCAGCTCAGGTTCGGTGAACTTAAGCTGCTGTATGTGTCGCCAGAACGTTTATTGCAGGGGGATTTTTTAAGCC
GGCTTGATGAACTGCATATCAGCCTGTTTGCAGTGGATGAAGCCCACTGTATCAGTGAGTGGGGGCACGATTTCAGGCCC
GAATATGCTGCGCTGGGCCAGCTTAAGCAGCGCTTCCCCCATGTGCCTGTGATGGCACTTACTGCCACTGCAGATGAAGC
AACCCGCAGCAGTATCTGCGAACGTCTTGGCATACAGCCATTTCAGCATCTTGCCAGTTTCGACAGACCCAATATTCGCT
ACACAGTGGCCGAAAAGCTTAATGCAGCCAACCAATTGCGACAATTTATCCAGTCGCAAAAGGGCGCCAACGGCATTGTG
TACTGCAGCAGCCGTCGCCGGGTGGATGAGGTTGCCGAGCGGCTCAGACAGCAGGGATTCTATGCTGAGGGTTATCATGC
GGGCATGACTCAGGATGAACGGGCGAGCGTACAGGACAGGTTTCTGAAAGATCAAATCGATGTGGTGGTGGCCACAGTCG
CCTTTGGTATGGGGATTAACAAGTCCAACGTGCGCTTTGTGGTGCATTACGATATTCCCAAGAGCATTGAGTCCTATTAC
CAGGAAACCGGCAGAGCCGGTCGGGATGGTCTGGATGCCGAGGCTTTGCTGCTATTTGACCCCGCCGATATAGGCCGGGT
GCGGCATCTGATTGAACAGCAGGAGCCCGGGCCTCAGCAGCAGGTGGAGTTTCATAAGCTGTATTCCATGGCGGCCTTTG
CCGAGGCGCAAACCTGCCGCCGTCAGGTATTGCTGCACTACTTTGGTGAAGCGGCAAACGAACCCTGCGGCAACTGTGAC
ATCTGCATCGACCCACCCAAACGTTACAACGGTACCGAAGATGCACAAAAGGTGCTTTCGTGTATTTACAGGCTAAATCA
ACGTTTTGGGGTCAATCATCTCATTGAAGTCTTGCGGGGTTCCAAAGCCGCTTCCGTGGTAGACCGGGGGCACGACAAGC
TGTCAACATGGGGCATTGGCAAAGAGAAGAGCACAGAGTATTGGCTGAGTGTCACCCGTCAGCTTATTCACCTGGGACTC
GCCAGCCAGGATATTACCCGTGGCTCGTCGGTACGCCTGAACAGCGCAGCCAGACCCGTTTTGAAAGGGGAGGTGGCGCT
GATGCTTGCCGAGCCTCGCCTTAGCCTCAGTGATGTGCCGCGTAAGCGCACATCGAGTCGAACGCCGCAAAATTACGATC
GTAAGTTGTTTGCCAGGCTCAAAAATTTGAGGCGCACTATAGCCGAAGAGCAGGATGTGCCGCCCTATCTGGTGTTCAAT
GATGCCACACTCGCTGAAATGGCATGGATGCTGCCCAAATCAGAGGCTGAGCTGTTAGCCGTTAACGGTGTGGGTGAACG
TAAGCTGGCTCGGTTTGGTGGTGAGTTTCTCGACGAGATAGCCGCTTACATCAGTGGGGATTAG

Upstream 100 bases:

>100_bases
GACATTTGGGGGCTCCCCGCCGAGCGTTCGGACGATTGCGACAAGACACAGGCCGCTCCCTTGGTTAGAATGACCGCCTT
GTTTATCTTACGGCAGTTTC

Downstream 100 bases:

>100_bases
TCATCAGTGTGCTGCGGGTCATGCCTCGGGTGGTGGCACGTTTGAGCAGGGTTTCTGAGGTATCAAATTGGTGCATACTG
GCTTGGCCAAGAAGAATTTT

Product: ATP-dependent DNA helicase RecQ

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 607; Mature: 607

Protein sequence:

>607_residues
MEQPASEHTQDPLSHCLQQVFGYRDFRPGQREVMTRVCQGEDCLVIMPTGGGKSLCYQVPALVLPGVTLVVSPLISLMKD
QVDSLIQSGVAAAYLNSSQPREQAIEVLRQLRFGELKLLYVSPERLLQGDFLSRLDELHISLFAVDEAHCISEWGHDFRP
EYAALGQLKQRFPHVPVMALTATADEATRSSICERLGIQPFQHLASFDRPNIRYTVAEKLNAANQLRQFIQSQKGANGIV
YCSSRRRVDEVAERLRQQGFYAEGYHAGMTQDERASVQDRFLKDQIDVVVATVAFGMGINKSNVRFVVHYDIPKSIESYY
QETGRAGRDGLDAEALLLFDPADIGRVRHLIEQQEPGPQQQVEFHKLYSMAAFAEAQTCRRQVLLHYFGEAANEPCGNCD
ICIDPPKRYNGTEDAQKVLSCIYRLNQRFGVNHLIEVLRGSKAASVVDRGHDKLSTWGIGKEKSTEYWLSVTRQLIHLGL
ASQDITRGSSVRLNSAARPVLKGEVALMLAEPRLSLSDVPRKRTSSRTPQNYDRKLFARLKNLRRTIAEEQDVPPYLVFN
DATLAEMAWMLPKSEAELLAVNGVGERKLARFGGEFLDEIAAYISGD

Sequences:

>Translated_607_residues
MEQPASEHTQDPLSHCLQQVFGYRDFRPGQREVMTRVCQGEDCLVIMPTGGGKSLCYQVPALVLPGVTLVVSPLISLMKD
QVDSLIQSGVAAAYLNSSQPREQAIEVLRQLRFGELKLLYVSPERLLQGDFLSRLDELHISLFAVDEAHCISEWGHDFRP
EYAALGQLKQRFPHVPVMALTATADEATRSSICERLGIQPFQHLASFDRPNIRYTVAEKLNAANQLRQFIQSQKGANGIV
YCSSRRRVDEVAERLRQQGFYAEGYHAGMTQDERASVQDRFLKDQIDVVVATVAFGMGINKSNVRFVVHYDIPKSIESYY
QETGRAGRDGLDAEALLLFDPADIGRVRHLIEQQEPGPQQQVEFHKLYSMAAFAEAQTCRRQVLLHYFGEAANEPCGNCD
ICIDPPKRYNGTEDAQKVLSCIYRLNQRFGVNHLIEVLRGSKAASVVDRGHDKLSTWGIGKEKSTEYWLSVTRQLIHLGL
ASQDITRGSSVRLNSAARPVLKGEVALMLAEPRLSLSDVPRKRTSSRTPQNYDRKLFARLKNLRRTIAEEQDVPPYLVFN
DATLAEMAWMLPKSEAELLAVNGVGERKLARFGGEFLDEIAAYISGD
>Mature_607_residues
MEQPASEHTQDPLSHCLQQVFGYRDFRPGQREVMTRVCQGEDCLVIMPTGGGKSLCYQVPALVLPGVTLVVSPLISLMKD
QVDSLIQSGVAAAYLNSSQPREQAIEVLRQLRFGELKLLYVSPERLLQGDFLSRLDELHISLFAVDEAHCISEWGHDFRP
EYAALGQLKQRFPHVPVMALTATADEATRSSICERLGIQPFQHLASFDRPNIRYTVAEKLNAANQLRQFIQSQKGANGIV
YCSSRRRVDEVAERLRQQGFYAEGYHAGMTQDERASVQDRFLKDQIDVVVATVAFGMGINKSNVRFVVHYDIPKSIESYY
QETGRAGRDGLDAEALLLFDPADIGRVRHLIEQQEPGPQQQVEFHKLYSMAAFAEAQTCRRQVLLHYFGEAANEPCGNCD
ICIDPPKRYNGTEDAQKVLSCIYRLNQRFGVNHLIEVLRGSKAASVVDRGHDKLSTWGIGKEKSTEYWLSVTRQLIHLGL
ASQDITRGSSVRLNSAARPVLKGEVALMLAEPRLSLSDVPRKRTSSRTPQNYDRKLFARLKNLRRTIAEEQDVPPYLVFN
DATLAEMAWMLPKSEAELLAVNGVGERKLARFGGEFLDEIAAYISGD

Specific function: Involved in the recF recombination pathway; its gene expression is under the regulation of the SOS system. It is a DNA helicase [H]

COG id: COG0514

COG function: function code L; Superfamily II DNA helicase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HRDC domain [H]

Homologues:

Organism=Homo sapiens, GI4557365, Length=644, Percent_Identity=35.2484472049689, Blast_Score=356, Evalue=3e-98,
Organism=Homo sapiens, GI14591902, Length=453, Percent_Identity=40.1766004415011, Blast_Score=322, Evalue=6e-88,
Organism=Homo sapiens, GI14591904, Length=453, Percent_Identity=40.1766004415011, Blast_Score=322, Evalue=6e-88,
Organism=Homo sapiens, GI110735439, Length=495, Percent_Identity=37.5757575757576, Blast_Score=322, Evalue=8e-88,
Organism=Homo sapiens, GI169218196, Length=495, Percent_Identity=37.5757575757576, Blast_Score=322, Evalue=8e-88,
Organism=Homo sapiens, GI148612816, Length=438, Percent_Identity=37.4429223744292, Blast_Score=269, Evalue=5e-72,
Organism=Homo sapiens, GI51242947, Length=386, Percent_Identity=39.119170984456, Blast_Score=258, Evalue=1e-68,
Organism=Homo sapiens, GI51242943, Length=386, Percent_Identity=39.119170984456, Blast_Score=258, Evalue=2e-68,
Organism=Homo sapiens, GI284005309, Length=346, Percent_Identity=38.4393063583815, Blast_Score=217, Evalue=2e-56,
Organism=Homo sapiens, GI4758138, Length=340, Percent_Identity=26.4705882352941, Blast_Score=89, Evalue=9e-18,
Organism=Homo sapiens, GI148613856, Length=339, Percent_Identity=25.6637168141593, Blast_Score=86, Evalue=1e-16,
Organism=Homo sapiens, GI38201710, Length=339, Percent_Identity=25.6637168141593, Blast_Score=86, Evalue=1e-16,
Organism=Homo sapiens, GI222352149, Length=398, Percent_Identity=22.8643216080402, Blast_Score=77, Evalue=4e-14,
Organism=Homo sapiens, GI7661920, Length=118, Percent_Identity=29.6610169491525, Blast_Score=72, Evalue=2e-12,
Organism=Homo sapiens, GI13514831, Length=372, Percent_Identity=23.6559139784946, Blast_Score=71, Evalue=3e-12,
Organism=Escherichia coli, GI48994977, Length=592, Percent_Identity=59.1216216216216, Blast_Score=741, Evalue=0.0,
Organism=Escherichia coli, GI87082221, Length=340, Percent_Identity=26.1764705882353, Blast_Score=85, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI25145561, Length=653, Percent_Identity=32.4655436447167, Blast_Score=328, Evalue=3e-90,
Organism=Caenorhabditis elegans, GI71987997, Length=409, Percent_Identity=40.8312958435208, Blast_Score=303, Evalue=1e-82,
Organism=Caenorhabditis elegans, GI71987993, Length=409, Percent_Identity=40.8312958435208, Blast_Score=303, Evalue=1e-82,
Organism=Caenorhabditis elegans, GI32564293, Length=670, Percent_Identity=30.4477611940298, Blast_Score=303, Evalue=1e-82,
Organism=Caenorhabditis elegans, GI17552866, Length=429, Percent_Identity=35.4312354312354, Blast_Score=243, Evalue=2e-64,
Organism=Caenorhabditis elegans, GI17537549, Length=380, Percent_Identity=22.3684210526316, Blast_Score=82, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI32565321, Length=390, Percent_Identity=24.6153846153846, Blast_Score=79, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI115533224, Length=341, Percent_Identity=25.2199413489736, Blast_Score=79, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI71987143, Length=364, Percent_Identity=23.9010989010989, Blast_Score=73, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI71995724, Length=116, Percent_Identity=28.448275862069, Blast_Score=67, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17507121, Length=116, Percent_Identity=28.448275862069, Blast_Score=67, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17555296, Length=350, Percent_Identity=22, Blast_Score=66, Evalue=6e-11,
Organism=Saccharomyces cerevisiae, GI6323844, Length=527, Percent_Identity=36.4326375711575, Blast_Score=328, Evalue=1e-90,
Organism=Saccharomyces cerevisiae, GI6324217, Length=336, Percent_Identity=23.8095238095238, Blast_Score=83, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6320224, Length=112, Percent_Identity=31.25, Blast_Score=79, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6325138, Length=140, Percent_Identity=26.4285714285714, Blast_Score=68, Evalue=5e-12,
Organism=Saccharomyces cerevisiae, GI6324778, Length=416, Percent_Identity=21.3942307692308, Blast_Score=66, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6322427, Length=334, Percent_Identity=24.251497005988, Blast_Score=65, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24646066, Length=634, Percent_Identity=35.4889589905363, Blast_Score=369, Evalue=1e-102,
Organism=Drosophila melanogaster, GI24664226, Length=448, Percent_Identity=34.8214285714286, Blast_Score=266, Evalue=3e-71,
Organism=Drosophila melanogaster, GI62472181, Length=448, Percent_Identity=34.8214285714286, Blast_Score=263, Evalue=2e-70,
Organism=Drosophila melanogaster, GI24664230, Length=448, Percent_Identity=34.8214285714286, Blast_Score=263, Evalue=2e-70,
Organism=Drosophila melanogaster, GI21358123, Length=356, Percent_Identity=37.0786516853933, Blast_Score=221, Evalue=8e-58,
Organism=Drosophila melanogaster, GI28574962, Length=338, Percent_Identity=26.0355029585799, Blast_Score=86, Evalue=8e-17,
Organism=Drosophila melanogaster, GI18857967, Length=356, Percent_Identity=24.438202247191, Blast_Score=80, Evalue=5e-15,
Organism=Drosophila melanogaster, GI21355075, Length=396, Percent_Identity=20.7070707070707, Blast_Score=76, Evalue=7e-14,
Organism=Drosophila melanogaster, GI24645031, Length=118, Percent_Identity=31.3559322033898, Blast_Score=74, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24644479, Length=343, Percent_Identity=23.0320699708455, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24644487, Length=343, Percent_Identity=23.0320699708455, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI45551833, Length=343, Percent_Identity=23.0320699708455, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24644485, Length=343, Percent_Identity=23.0320699708455, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI281361218, Length=343, Percent_Identity=23.0320699708455, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24644481, Length=343, Percent_Identity=23.0320699708455, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24644483, Length=343, Percent_Identity=23.0320699708455, Blast_Score=72, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR011545
- InterPro:   IPR004589
- InterPro:   IPR006293
- InterPro:   IPR002121
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR010997
- InterPro:   IPR018982 [H]

Pfam domain/function: PF00270 DEAD; PF00271 Helicase_C; PF00570 HRDC; PF09382 RQC [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 68099; Mature: 68099

Theoretical pI: Translated: 6.91; Mature: 6.91

Prosite motif: PS50967 HRDC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEQPASEHTQDPLSHCLQQVFGYRDFRPGQREVMTRVCQGEDCLVIMPTGGGKSLCYQVP
CCCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCEEEEEECCCCCHHHHHHH
ALVLPGVTLVVSPLISLMKDQVDSLIQSGVAAAYLNSSQPREQAIEVLRQLRFGELKLLY
HHHHCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCHHHHHHHHHHHCCCCEEEEE
VSPERLLQGDFLSRLDELHISLFAVDEAHCISEWGHDFRPEYAALGQLKQRFPHVPVMAL
ECHHHHHHHHHHHHHHHHHHEEEEECHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCEEEE
TATADEATRSSICERLGIQPFQHLASFDRPNIRYTVAEKLNAANQLRQFIQSQKGANGIV
EECHHHHHHHHHHHHHCCCHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHCCCCCCEE
YCSSRRRVDEVAERLRQQGFYAEGYHAGMTQDERASVQDRFLKDQIDVVVATVAFGMGIN
EECCCCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
KSNVRFVVHYDIPKSIESYYQETGRAGRDGLDAEALLLFDPADIGRVRHLIEQQEPGPQQ
CCCCEEEEEECCHHHHHHHHHHHCCCCCCCCCCCEEEEECCHHHHHHHHHHHHCCCCCHH
QVEFHKLYSMAAFAEAQTCRRQVLLHYFGEAANEPCGNCDICIDPPKRYNGTEDAQKVLS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCCCCCCHHHHHHHH
CIYRLNQRFGVNHLIEVLRGSKAASVVDRGHDKLSTWGIGKEKSTEYWLSVTRQLIHLGL
HHHHHHHHCCHHHHHHHHHCCHHHHHHHCCCCHHHHCCCCCCCCHHHHHHHHHHHHHHCC
ASQDITRGSSVRLNSAARPVLKGEVALMLAEPRLSLSDVPRKRTSSRTPQNYDRKLFARL
CHHHCCCCCCEEECCCCCCHHCCCEEEEEECCCCCHHHCCCHHCCCCCCCHHHHHHHHHH
KNLRRTIAEEQDVPPYLVFNDATLAEMAWMLPKSEAELLAVNGVGERKLARFGGEFLDEI
HHHHHHHHHHCCCCCEEEECCCHHHHHHHHCCCCCCCEEEECCCCHHHHHHHHHHHHHHH
AAYISGD
HHHHCCC
>Mature Secondary Structure
MEQPASEHTQDPLSHCLQQVFGYRDFRPGQREVMTRVCQGEDCLVIMPTGGGKSLCYQVP
CCCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCEEEEEECCCCCHHHHHHH
ALVLPGVTLVVSPLISLMKDQVDSLIQSGVAAAYLNSSQPREQAIEVLRQLRFGELKLLY
HHHHCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCHHHHHHHHHHHCCCCEEEEE
VSPERLLQGDFLSRLDELHISLFAVDEAHCISEWGHDFRPEYAALGQLKQRFPHVPVMAL
ECHHHHHHHHHHHHHHHHHHEEEEECHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCEEEE
TATADEATRSSICERLGIQPFQHLASFDRPNIRYTVAEKLNAANQLRQFIQSQKGANGIV
EECHHHHHHHHHHHHHCCCHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHCCCCCCEE
YCSSRRRVDEVAERLRQQGFYAEGYHAGMTQDERASVQDRFLKDQIDVVVATVAFGMGIN
EECCCCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
KSNVRFVVHYDIPKSIESYYQETGRAGRDGLDAEALLLFDPADIGRVRHLIEQQEPGPQQ
CCCCEEEEEECCHHHHHHHHHHHCCCCCCCCCCCEEEEECCHHHHHHHHHHHHCCCCCHH
QVEFHKLYSMAAFAEAQTCRRQVLLHYFGEAANEPCGNCDICIDPPKRYNGTEDAQKVLS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCCCCCCHHHHHHHH
CIYRLNQRFGVNHLIEVLRGSKAASVVDRGHDKLSTWGIGKEKSTEYWLSVTRQLIHLGL
HHHHHHHHCCHHHHHHHHHCCHHHHHHHCCCCHHHHCCCCCCCCHHHHHHHHHHHHHHCC
ASQDITRGSSVRLNSAARPVLKGEVALMLAEPRLSLSDVPRKRTSSRTPQNYDRKLFARL
CHHHCCCCCCEEECCCCCCHHCCCEEEEEECCCCCHHHCCCHHCCCCCCCHHHHHHHHHH
KNLRRTIAEEQDVPPYLVFNDATLAEMAWMLPKSEAELLAVNGVGERKLARFGGEFLDEI
HHHHHHHHHHCCCCCEEEECCCHHHHHHHHCCCCCCCEEEECCCCHHHHHHHHHHHHHHH
AAYISGD
HHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3027506; 1379743; 9278503; 2164680 [H]