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The map label for this gene is argA [H]

Identifier: 119773471

GI number: 119773471

Start: 395962

End: 397284

Strand: Direct

Name: argA [H]

Synonym: Sama_0330

Alternate gene names: 119773471

Gene position: 395962-397284 (Clockwise)

Preceding gene: 119773470

Following gene: 119773472

Centisome position: 9.2

GC content: 55.48

Gene sequence:

>1323_bases
GTGCGAACTACCGAATTGGTTGACGGTTTTCGTCATTCCGCCCCCTATGTAAATGCTCACCGCGGCAAGACATTTGTTGT
CATGCTGGGCGGCGAAGCCATGGTACAACCCCAATTTCGCGCCATCATCAACGATGTGGCCTTGCTGCACAGCTTGGGGA
TCCGTATCGTGCTGGTGTACGGTGCCAGGCCGCAGATTGATGCGGCGCTTGAGCTGCATGGCATTGCGCCTGCCTACCAC
AACGGGGTACGCATCACCGATGAAGATACTCTGAAGGTGATCAAGCAGGTTGCCGGAGCGCTCCAATTCGACATTACTGC
ACGGCTTTCCATGAGTCTGTCCAATACTCCCATGCAGGGCACGCAGCTGAACGTTGTCAGCGGCAACTTTGTGATTGCCC
AGCCGCTGGGCGTGGAAGATGGGGTGGATTTTTGCCTGTCTGGCCGGGTGCGTCGTATCGACGTGAATGGGCTTAAGCAT
CAGCTCGACAGCCGCGGTATTGTGCTGATGGGGCCGATTGCTGCCTCGGTTACCGGTGAAAGTTTTAACCTGACGGCCGA
GGAAGTAGCCACTCAGGTGGCGGTGAAGCTCAAAGCCGATAAGATGATAGGGTTCAGCTCACAGAACGGTATTCTGGATC
GTAACGGCGAAGTGATTGCCGAGCTGATGCCAAACGATGCCCAGAAGATTTTCGCCAAGATGCAGGAAGGCGGTCAGGCC
TGCGTCGGTACCCTGGCGTTTTTGAAGGCGAGCATTGATGCCTGCCGCAATGGGGTACCACGTTGCCATCTGGTGAGCTA
TCTCGAAGATGGTGCCTTGCTGCAAGAGCTATTCTCCCGTGATGGCATAGGTACACAAATCGTGACCGAAAGCGCCGAGC
GTCTGCGCCGCGCATCGATTGCCGATATTGGTGGCATTCTTAACCTGATCCGCCCAATGGAAGAGCAGGGCATTCTGGTG
CGCCGTTCCCGCGAGCAGCTCGAGATGGAAATCGAGCAGTTTATGGTTATTGAACGGGACGGTCTGGTTATCGGCTGCGC
CGCGCTGTATCCCTTTGAAGAAGACAATGCCGGTGAGTTTGCCTGCCTGGTGGTGCATCCTGATTACCGCGATGCCGACC
GGGGGAGTTTGCTGCTCAAGAACATCATAGGCCAGGCAAGGGTGAGGGGCTATGCCCGCCTGTTTGCGCTTACCACCCGC
AGTATTCACTGGTTCCTGGAGCACGGCTTTGAGTTGGTGGAGGTAGAGGCCTTACCGACCAAGAAAAAGCAGCTTTACAA
CTATCAACGTCGCTCAAAAATTCTCGCATTGGATCTGCAATAA

Upstream 100 bases:

>100_bases
ATAAATGCTTTAAATGTGAATTTAAATTCACTAAAATTGCGCAAGAATTCAACTTGGCGCAGTGTGTGCTGCGTCGGAGA
CTGTGAGGACAAAACAGCCC

Downstream 100 bases:

>100_bases
TCCTTCCTGCCGAAACAACCAGCCACATGGCTGGTTGTTTGTTTATTGCAGCTGCTAATTTGTCATTTGAGGTCTAATGC
TCTTGACATATTATGTCTTT

Product: N-acetylglutamate synthase

Products: NA

Alternate protein names: N-acetylglutamate synthase; AGS; NAGS [H]

Number of amino acids: Translated: 440; Mature: 440

Protein sequence:

>440_residues
MRTTELVDGFRHSAPYVNAHRGKTFVVMLGGEAMVQPQFRAIINDVALLHSLGIRIVLVYGARPQIDAALELHGIAPAYH
NGVRITDEDTLKVIKQVAGALQFDITARLSMSLSNTPMQGTQLNVVSGNFVIAQPLGVEDGVDFCLSGRVRRIDVNGLKH
QLDSRGIVLMGPIAASVTGESFNLTAEEVATQVAVKLKADKMIGFSSQNGILDRNGEVIAELMPNDAQKIFAKMQEGGQA
CVGTLAFLKASIDACRNGVPRCHLVSYLEDGALLQELFSRDGIGTQIVTESAERLRRASIADIGGILNLIRPMEEQGILV
RRSREQLEMEIEQFMVIERDGLVIGCAALYPFEEDNAGEFACLVVHPDYRDADRGSLLLKNIIGQARVRGYARLFALTTR
SIHWFLEHGFELVEVEALPTKKKQLYNYQRRSKILALDLQ

Sequences:

>Translated_440_residues
MRTTELVDGFRHSAPYVNAHRGKTFVVMLGGEAMVQPQFRAIINDVALLHSLGIRIVLVYGARPQIDAALELHGIAPAYH
NGVRITDEDTLKVIKQVAGALQFDITARLSMSLSNTPMQGTQLNVVSGNFVIAQPLGVEDGVDFCLSGRVRRIDVNGLKH
QLDSRGIVLMGPIAASVTGESFNLTAEEVATQVAVKLKADKMIGFSSQNGILDRNGEVIAELMPNDAQKIFAKMQEGGQA
CVGTLAFLKASIDACRNGVPRCHLVSYLEDGALLQELFSRDGIGTQIVTESAERLRRASIADIGGILNLIRPMEEQGILV
RRSREQLEMEIEQFMVIERDGLVIGCAALYPFEEDNAGEFACLVVHPDYRDADRGSLLLKNIIGQARVRGYARLFALTTR
SIHWFLEHGFELVEVEALPTKKKQLYNYQRRSKILALDLQ
>Mature_440_residues
MRTTELVDGFRHSAPYVNAHRGKTFVVMLGGEAMVQPQFRAIINDVALLHSLGIRIVLVYGARPQIDAALELHGIAPAYH
NGVRITDEDTLKVIKQVAGALQFDITARLSMSLSNTPMQGTQLNVVSGNFVIAQPLGVEDGVDFCLSGRVRRIDVNGLKH
QLDSRGIVLMGPIAASVTGESFNLTAEEVATQVAVKLKADKMIGFSSQNGILDRNGEVIAELMPNDAQKIFAKMQEGGQA
CVGTLAFLKASIDACRNGVPRCHLVSYLEDGALLQELFSRDGIGTQIVTESAERLRRASIADIGGILNLIRPMEEQGILV
RRSREQLEMEIEQFMVIERDGLVIGCAALYPFEEDNAGEFACLVVHPDYRDADRGSLLLKNIIGQARVRGYARLFALTTR
SIHWFLEHGFELVEVEALPTKKKQLYNYQRRSKILALDLQ

Specific function: Arginine biosynthesis; first step. [C]

COG id: COG0548

COG function: function code E; Acetylglutamate kinase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 N-acetyltransferase domain [H]

Homologues:

Organism=Escherichia coli, GI1789181, Length=438, Percent_Identity=65.0684931506849, Blast_Score=618, Evalue=1e-178,
Organism=Saccharomyces cerevisiae, GI6320913, Length=291, Percent_Identity=23.0240549828179, Blast_Score=71, Evalue=4e-13,

Paralogues:

None

Copy number: 2,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000182
- InterPro:   IPR016181
- InterPro:   IPR001048
- InterPro:   IPR010167 [H]

Pfam domain/function: PF00696 AA_kinase; PF00583 Acetyltransf_1 [H]

EC number: =2.3.1.1 [H]

Molecular weight: Translated: 48452; Mature: 48452

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS00290 IG_MHC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRTTELVDGFRHSAPYVNAHRGKTFVVMLGGEAMVQPQFRAIINDVALLHSLGIRIVLVY
CCCHHHHHHHHHCCCCEECCCCCEEEEEECCCEEECHHHHHHHHHHHHHHHCCEEEEEEE
GARPQIDAALELHGIAPAYHNGVRITDEDTLKVIKQVAGALQFDITARLSMSLSNTPMQG
CCCCCCCCEEEEECCCHHHCCCEEECCHHHHHHHHHHHHHEEEEEEEEEEEEECCCCCCC
TQLNVVSGNFVIAQPLGVEDGVDFCLSGRVRRIDVNGLKHQLDSRGIVLMGPIAASVTGE
CEEEEEECCEEEEECCCCCCCCHHHHCCCEEEEECCHHHHHHCCCCEEEECCEEEEECCC
SFNLTAEEVATQVAVKLKADKMIGFSSQNGILDRNGEVIAELMPNDAQKIFAKMQEGGQA
CCCCCHHHHHHHHHEEEEHHHEECCCCCCCCCCCCCCEEEECCCCHHHHHHHHHHHCCHH
CVGTLAFLKASIDACRNGVPRCHLVSYLEDGALLQELFSRDGIGTQIVTESAERLRRASI
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
ADIGGILNLIRPMEEQGILVRRSREQLEMEIEQFMVIERDGLVIGCAALYPFEEDNAGEF
HHHHHHHHHHCCHHHCCEEEECCHHHHHHHHHHHEEEECCCEEEEEEEECCCCCCCCCCE
ACLVVHPDYRDADRGSLLLKNIIGQARVRGYARLFALTTRSIHWFLEHGFELVEVEALPT
EEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCC
KKKQLYNYQRRSKILALDLQ
HHHHHHHHHHHCEEEEEECC
>Mature Secondary Structure
MRTTELVDGFRHSAPYVNAHRGKTFVVMLGGEAMVQPQFRAIINDVALLHSLGIRIVLVY
CCCHHHHHHHHHCCCCEECCCCCEEEEEECCCEEECHHHHHHHHHHHHHHHCCEEEEEEE
GARPQIDAALELHGIAPAYHNGVRITDEDTLKVIKQVAGALQFDITARLSMSLSNTPMQG
CCCCCCCCEEEEECCCHHHCCCEEECCHHHHHHHHHHHHHEEEEEEEEEEEEECCCCCCC
TQLNVVSGNFVIAQPLGVEDGVDFCLSGRVRRIDVNGLKHQLDSRGIVLMGPIAASVTGE
CEEEEEECCEEEEECCCCCCCCHHHHCCCEEEEECCHHHHHHCCCCEEEECCEEEEECCC
SFNLTAEEVATQVAVKLKADKMIGFSSQNGILDRNGEVIAELMPNDAQKIFAKMQEGGQA
CCCCCHHHHHHHHHEEEEHHHEECCCCCCCCCCCCCCEEEECCCCHHHHHHHHHHHCCHH
CVGTLAFLKASIDACRNGVPRCHLVSYLEDGALLQELFSRDGIGTQIVTESAERLRRASI
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
ADIGGILNLIRPMEEQGILVRRSREQLEMEIEQFMVIERDGLVIGCAALYPFEEDNAGEF
HHHHHHHHHHCCHHHCCEEEECCHHHHHHHHHHHEEEECCCEEEEEEEECCCCCCCCCCE
ACLVVHPDYRDADRGSLLLKNIIGQARVRGYARLFALTTRSIHWFLEHGFELVEVEALPT
EEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCC
KKKQLYNYQRRSKILALDLQ
HHHHHHHHHHHCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12368813 [H]