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The map label for this gene is tlpA [H]

Identifier: 119773392

GI number: 119773392

Start: 274865

End: 275446

Strand: Direct

Name: tlpA [H]

Synonym: Sama_0251

Alternate gene names: 119773392

Gene position: 274865-275446 (Clockwise)

Preceding gene: 119773391

Following gene: 119773393

Centisome position: 6.38

GC content: 51.89

Gene sequence:

>582_bases
ATGAAGCGCATAGTCTGCGCACTGATGTTGGCGGCCTCCGGGGCCGCCATTGCTTATCCGGGGATGCAACAGCAAATGGT
GCAGCCAGCATCCAGTGTGGATCTCATCCGCCAGTTGCCACATCCTTTCGCGATTGACGTTGTGCCCTTTGAAGATGCAA
ACGGTAAGGCCGTCGACTTCAGTCAGTATCAGGGCAAGGTTGTCATGGTGAATATGTGGGCTACCTGGTGTCCGCCGTGT
GTCAGGGAAATACCGGCATTGGAACGTCTTAAAGCAAAGATGGATCCAAAAGATTTTGCCTTCCTGCCCATCTCTATTGA
TGCGGGTGGTAAAGCAGAAGTGGATGCTTTCTTAAAGGCGAAGGGAATGGAGGACTTCGGTTCATTCTTCGATGCGCCGC
AAAACTTAAGGCAGGTGTTTCCCCTCGATACAATTCCAGCCACCTTTATTCTTAATAGAGAAGGGCAGCTGGTGGCCTTT
GTCAGAAGCTTTGTCGATTGGGATGACCCTAAGGCAGAAGCCCTGCTTAAAGGGATCATCGAAGCACCTTTAGCCGCCCC
CGCCGTAAAAGCGGCCAAATAG

Upstream 100 bases:

>100_bases
CAGCCGATGCTGCCGATTTGACCCCTGAGCAGCAGGCAGAACTCGATGCCTTGCTGAAAGGTAGCCAGCCCGAAGCCGAT
AACGGCAAGGGTAAAAAATC

Downstream 100 bases:

>100_bases
TCACTCGGTCCTGTCTCTGGATCCATGAAAGATCGCATACTGTCTAAAAGATCGACATGCGATCTTTTTCTTTTAAAAAG
GGCTTGCACTTCGAGCCAGC

Product: thioredoxin

Products: NA

Alternate protein names: Cytochrome c biogenesis protein tlpA [H]

Number of amino acids: Translated: 193; Mature: 193

Protein sequence:

>193_residues
MKRIVCALMLAASGAAIAYPGMQQQMVQPASSVDLIRQLPHPFAIDVVPFEDANGKAVDFSQYQGKVVMVNMWATWCPPC
VREIPALERLKAKMDPKDFAFLPISIDAGGKAEVDAFLKAKGMEDFGSFFDAPQNLRQVFPLDTIPATFILNREGQLVAF
VRSFVDWDDPKAEALLKGIIEAPLAAPAVKAAK

Sequences:

>Translated_193_residues
MKRIVCALMLAASGAAIAYPGMQQQMVQPASSVDLIRQLPHPFAIDVVPFEDANGKAVDFSQYQGKVVMVNMWATWCPPC
VREIPALERLKAKMDPKDFAFLPISIDAGGKAEVDAFLKAKGMEDFGSFFDAPQNLRQVFPLDTIPATFILNREGQLVAF
VRSFVDWDDPKAEALLKGIIEAPLAAPAVKAAK
>Mature_193_residues
MKRIVCALMLAASGAAIAYPGMQQQMVQPASSVDLIRQLPHPFAIDVVPFEDANGKAVDFSQYQGKVVMVNMWATWCPPC
VREIPALERLKAKMDPKDFAFLPISIDAGGKAEVDAFLKAKGMEDFGSFFDAPQNLRQVFPLDTIPATFILNREGQLVAF
VRSFVDWDDPKAEALLKGIIEAPLAAPAVKAAK

Specific function: Involved in cytochrome aa3 assembly [H]

COG id: COG0526

COG function: function code OC; Thiol-disulfide isomerase and thioredoxins

Gene ontology:

Cell location: Cell membrane; Single-pass type II membrane protein; Periplasmic side [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013740
- InterPro:   IPR005746
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR012335 [H]

Pfam domain/function: PF08534 Redoxin [H]

EC number: NA

Molecular weight: Translated: 21081; Mature: 21081

Theoretical pI: Translated: 5.29; Mature: 5.29

Prosite motif: PS00194 THIOREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRIVCALMLAASGAAIAYPGMQQQMVQPASSVDLIRQLPHPFAIDVVPFEDANGKAVDF
CHHHHHHHHHHHCCCEEECCCHHHHHHCCHHHHHHHHHCCCCEEEEEEECCCCCCCEEEH
SQYQGKVVMVNMWATWCPPCVREIPALERLKAKMDPKDFAFLPISIDAGGKAEVDAFLKA
HHHCCEEEEEECCCHHCCHHHHHCCHHHHHHHHCCCCCEEEEEEEECCCCCHHHHHHHHH
KGMEDFGSFFDAPQNLRQVFPLDTIPATFILNREGQLVAFVRSFVDWDDPKAEALLKGII
CCCHHHHHHHCCHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHCCCCHHHHHHHHHHH
EAPLAAPAVKAAK
HCCCCCCHHCCCC
>Mature Secondary Structure
MKRIVCALMLAASGAAIAYPGMQQQMVQPASSVDLIRQLPHPFAIDVVPFEDANGKAVDF
CHHHHHHHHHHHCCCEEECCCHHHHHHCCHHHHHHHHHCCCCEEEEEEECCCCCCCEEEH
SQYQGKVVMVNMWATWCPPCVREIPALERLKAKMDPKDFAFLPISIDAGGKAEVDAFLKA
HHHCCEEEEEECCCHHCCHHHHHCCHHHHHHHHCCCCCEEEEEEEECCCCCHHHHHHHHH
KGMEDFGSFFDAPQNLRQVFPLDTIPATFILNREGQLVAFVRSFVDWDDPKAEALLKGII
CCCHHHHHHHCCHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHCCCCHHHHHHHHHHH
EAPLAAPAVKAAK
HCCCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8253065; 12597275 [H]