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The map label for this gene is pyrH

Identifier: 119717465

GI number: 119717465

Start: 3443328

End: 3444041

Strand: Reverse

Name: pyrH

Synonym: Noca_3241

Alternate gene names: 119717465

Gene position: 3444041-3443328 (Counterclockwise)

Preceding gene: 119717466

Following gene: 119717464

Centisome position: 69.08

GC content: 67.65

Gene sequence:

>714_bases
GTGACCGGATACAAGCGCGTCCTGCTCAAGCTGTCGGGCGAGATGTTCGGCGGGGGCAAGGTCGGCGTCGACCCTGACGT
CGTCCAGACGGTGGCCCGCGAGATCGCCGCCGTCGTGAACGCCGGGGTGCAGATCGCGATCGTGACCGGCGGCGGCAACT
TCTTCCGCGGCGCGGAGCTCCAGCAGCGCGGCATGGACCGCGTCCGTGCGGACTACATGGGCATGCTCGGCATCGTGATG
AACTGCCTGGCCCTCCAGGACTTCCTGGAGAAGCTGGGTGTCGAGACTCGCGTGCAGACCGCCATCACCATGGGCCAGGT
CGCAGAGCCCTACATCCCACGGCGGGCGATCCGGCACATGGAGAAGGGTCGCGTCGTGATCTTCGGCGCCGGCATGGGCA
TGCCCTTCTTCTCCACCGACACGGTCGCGGTGCAGCGGGCGCTGGAGAGCCGGTGCGACGTCGTGCTCGTGGCCAAGAAC
GGGGTCGACGGCGTCTACACCGCCGACCCCCACAAGGACCCGACCGCGACCAAGTTCGACGACCTCACCTACGACGAGGC
CATCGCGCGGGGCTTGAGGATCATGGACCAGACCGCGTTCGCGCTCTGTGGGGAGAACAAGCTCCCGATGGTGGTGTTCG
GCATGGAGCCGGAGGGCAACATCCTGCGCGTCGTGCAGGGTGAGAGGATTGGCACGCTCGTGACCGCGGGCTGA

Upstream 100 bases:

>100_bases
ATAGGTTCTAGCCCAGACCAATCGAGGAGGCCGGTTCGATGACAGCGACCCTGATCATCGGACCGGCCTTCTCGCTTCCT
GCCCCACGAAGGAGCCGCCC

Downstream 100 bases:

>100_bases
TCGCCCGGTCCTGAGCACCTACCAGCGACGCTAGGAGTACCCGTGATCAACGACATCCTCAACGAGGCCGACGGCAAGAT
GGACAAGTCGGTCGAGGCGA

Product: uridylate kinase

Products: NA

Alternate protein names: UK; Uridine monophosphate kinase; UMP kinase; UMPK

Number of amino acids: Translated: 237; Mature: 236

Protein sequence:

>237_residues
MTGYKRVLLKLSGEMFGGGKVGVDPDVVQTVAREIAAVVNAGVQIAIVTGGGNFFRGAELQQRGMDRVRADYMGMLGIVM
NCLALQDFLEKLGVETRVQTAITMGQVAEPYIPRRAIRHMEKGRVVIFGAGMGMPFFSTDTVAVQRALESRCDVVLVAKN
GVDGVYTADPHKDPTATKFDDLTYDEAIARGLRIMDQTAFALCGENKLPMVVFGMEPEGNILRVVQGERIGTLVTAG

Sequences:

>Translated_237_residues
MTGYKRVLLKLSGEMFGGGKVGVDPDVVQTVAREIAAVVNAGVQIAIVTGGGNFFRGAELQQRGMDRVRADYMGMLGIVM
NCLALQDFLEKLGVETRVQTAITMGQVAEPYIPRRAIRHMEKGRVVIFGAGMGMPFFSTDTVAVQRALESRCDVVLVAKN
GVDGVYTADPHKDPTATKFDDLTYDEAIARGLRIMDQTAFALCGENKLPMVVFGMEPEGNILRVVQGERIGTLVTAG
>Mature_236_residues
TGYKRVLLKLSGEMFGGGKVGVDPDVVQTVAREIAAVVNAGVQIAIVTGGGNFFRGAELQQRGMDRVRADYMGMLGIVMN
CLALQDFLEKLGVETRVQTAITMGQVAEPYIPRRAIRHMEKGRVVIFGAGMGMPFFSTDTVAVQRALESRCDVVLVAKNG
VDGVYTADPHKDPTATKFDDLTYDEAIARGLRIMDQTAFALCGENKLPMVVFGMEPEGNILRVVQGERIGTLVTAG

Specific function: Catalyzes the reversible phosphorylation of UMP to UDP

COG id: COG0528

COG function: function code F; Uridylate kinase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UMP kinase family

Homologues:

Organism=Escherichia coli, GI1786367, Length=233, Percent_Identity=48.4978540772532, Blast_Score=215, Evalue=2e-57,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PYRH_NOCSJ (A1SLQ8)

Other databases:

- EMBL:   CP000509
- RefSeq:   YP_924430.1
- ProteinModelPortal:   A1SLQ8
- SMR:   A1SLQ8
- STRING:   A1SLQ8
- GeneID:   4599179
- GenomeReviews:   CP000509_GR
- KEGG:   nca:Noca_3241
- eggNOG:   COG0528
- HOGENOM:   HBG497552
- OMA:   RHMEKGR
- BioCyc:   NSP35761:NOCA_3241-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01220_B
- InterPro:   IPR001048
- InterPro:   IPR011817
- InterPro:   IPR015963
- Gene3D:   G3DSA:3.40.1160.10
- PIRSF:   PIRSF005650
- TIGRFAMs:   TIGR02075

Pfam domain/function: PF00696 AA_kinase; SSF53633 Aa_kinase

EC number: =2.7.4.22

Molecular weight: Translated: 25589; Mature: 25458

Theoretical pI: Translated: 6.53; Mature: 6.53

Prosite motif: NA

Important sites: BINDING 51-51 BINDING 52-52 BINDING 56-56 BINDING 71-71 BINDING 160-160 BINDING 166-166 BINDING 169-169

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
5.5 %Met     (Translated Protein)
6.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
5.1 %Met     (Mature Protein)
6.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGYKRVLLKLSGEMFGGGKVGVDPDVVQTVAREIAAVVNAGVQIAIVTGGGNFFRGAEL
CCHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCHH
QQRGMDRVRADYMGMLGIVMNCLALQDFLEKLGVETRVQTAITMGQVAEPYIPRRAIRHM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCHHHHHHHH
EKGRVVIFGAGMGMPFFSTDTVAVQRALESRCDVVLVAKNGVDGVYTADPHKDPTATKFD
HCCCEEEEECCCCCCCCCCHHHHHHHHHHHHCCEEEEECCCCCCCEECCCCCCCCCCCCC
DLTYDEAIARGLRIMDQTAFALCGENKLPMVVFGMEPEGNILRVVQGERIGTLVTAG
CCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCEEEEECCCCCCEEEECC
>Mature Secondary Structure 
TGYKRVLLKLSGEMFGGGKVGVDPDVVQTVAREIAAVVNAGVQIAIVTGGGNFFRGAEL
CHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCHH
QQRGMDRVRADYMGMLGIVMNCLALQDFLEKLGVETRVQTAITMGQVAEPYIPRRAIRHM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCHHHHHHHH
EKGRVVIFGAGMGMPFFSTDTVAVQRALESRCDVVLVAKNGVDGVYTADPHKDPTATKFD
HCCCEEEEECCCCCCCCCCHHHHHHHHHHHHCCEEEEECCCCCCCEECCCCCCCCCCCCC
DLTYDEAIARGLRIMDQTAFALCGENKLPMVVFGMEPEGNILRVVQGERIGTLVTAG
CCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCEEEEECCCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA