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The map label for this gene is frr

Identifier: 119717464

GI number: 119717464

Start: 3442728

End: 3443285

Strand: Reverse

Name: frr

Synonym: Noca_3240

Alternate gene names: 119717464

Gene position: 3443285-3442728 (Counterclockwise)

Preceding gene: 119717465

Following gene: 119717463

Centisome position: 69.06

GC content: 66.67

Gene sequence:

>558_bases
GTGATCAACGACATCCTCAACGAGGCCGACGGCAAGATGGACAAGTCGGTCGAGGCGACGCGCGAGGAGTTCGCGGCGAT
CCGCGCCGGCCGGGTCAACCCGAGCATGTTCAACAAGATCGTCGTCGACTACTACGGCTCGCCGACGCCGCTCCAGCAGC
TCGCCTCGTTCACCGCCCCTGAGGCGCGGATCATCCTGATCGCACCGTACGACCAGGGCGCGATGCACAACATCCTCAAG
GCGATCCGCGACTCCGACCTGGGCGTCAACCCGGCCGACGACGGCAAGGTGATCCGCTGCGTGTTCCCGGAGCTCACCGA
GGAGCGCCGCAAGGAGTACATCAAGATCTCCCGGCACAAGGCCGAGGAGGGCCGGGTGGCGGTCCGCAACCTGCGGCGTA
CCGCCAAGCAGCACCTCGAGCGCCTCGAGAAGGACGGCGAGGTCGGCCAGGACGACCTGACCGGGGCCGAGAAGCGCCTC
GACGGCCTGACCAAGAAGCACACCGACGCCATCGACGAGATGCTCAAGCACAAGGAGGCCGAGCTGCTCGAGGTCTGA

Upstream 100 bases:

>100_bases
CAACATCCTGCGCGTCGTGCAGGGTGAGAGGATTGGCACGCTCGTGACCGCGGGCTGATCGCCCGGTCCTGAGCACCTAC
CAGCGACGCTAGGAGTACCC

Downstream 100 bases:

>100_bases
GCACTCGACAAGCCATGTCCGACGCTCCGTCCGGGATGCCGCCGGCGACCCAGCCTCCCGTCCCCTCGTCCGTGCCGTCC
GGCTCGGGCCCGCCGCTGAA

Product: ribosome recycling factor

Products: NA

Alternate protein names: RRF; Ribosome-releasing factor

Number of amino acids: Translated: 185; Mature: 185

Protein sequence:

>185_residues
MINDILNEADGKMDKSVEATREEFAAIRAGRVNPSMFNKIVVDYYGSPTPLQQLASFTAPEARIILIAPYDQGAMHNILK
AIRDSDLGVNPADDGKVIRCVFPELTEERRKEYIKISRHKAEEGRVAVRNLRRTAKQHLERLEKDGEVGQDDLTGAEKRL
DGLTKKHTDAIDEMLKHKEAELLEV

Sequences:

>Translated_185_residues
MINDILNEADGKMDKSVEATREEFAAIRAGRVNPSMFNKIVVDYYGSPTPLQQLASFTAPEARIILIAPYDQGAMHNILK
AIRDSDLGVNPADDGKVIRCVFPELTEERRKEYIKISRHKAEEGRVAVRNLRRTAKQHLERLEKDGEVGQDDLTGAEKRL
DGLTKKHTDAIDEMLKHKEAELLEV
>Mature_185_residues
MINDILNEADGKMDKSVEATREEFAAIRAGRVNPSMFNKIVVDYYGSPTPLQQLASFTAPEARIILIAPYDQGAMHNILK
AIRDSDLGVNPADDGKVIRCVFPELTEERRKEYIKISRHKAEEGRVAVRNLRRTAKQHLERLEKDGEVGQDDLTGAEKRL
DGLTKKHTDAIDEMLKHKEAELLEV

Specific function: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another

COG id: COG0233

COG function: function code J; Ribosome recycling factor

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RRF family

Homologues:

Organism=Homo sapiens, GI20270317, Length=187, Percent_Identity=26.2032085561497, Blast_Score=67, Evalue=1e-11,
Organism=Escherichia coli, GI1786368, Length=184, Percent_Identity=45.6521739130435, Blast_Score=157, Evalue=6e-40,
Organism=Drosophila melanogaster, GI24661488, Length=176, Percent_Identity=26.1363636363636, Blast_Score=67, Evalue=9e-12,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): RRF_NOCSJ (A1SLQ7)

Other databases:

- EMBL:   CP000509
- RefSeq:   YP_924429.1
- ProteinModelPortal:   A1SLQ7
- SMR:   A1SLQ7
- STRING:   A1SLQ7
- GeneID:   4599178
- GenomeReviews:   CP000509_GR
- KEGG:   nca:Noca_3240
- eggNOG:   COG0233
- HOGENOM:   HBG533975
- OMA:   YYGAETP
- PhylomeDB:   A1SLQ7
- BioCyc:   NSP35761:NOCA_3240-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00040
- InterPro:   IPR002661
- InterPro:   IPR015998
- PANTHER:   PTHR20982
- PANTHER:   PTHR20982:SF3
- TIGRFAMs:   TIGR00496

Pfam domain/function: PF01765 RRF; SSF55194 Ribosome_recyc_fac

EC number: NA

Molecular weight: Translated: 20879; Mature: 20879

Theoretical pI: Translated: 6.05; Mature: 6.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MINDILNEADGKMDKSVEATREEFAAIRAGRVNPSMFNKIVVDYYGSPTPLQQLASFTAP
CCHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCHHHHHHHCCCC
EARIILIAPYDQGAMHNILKAIRDSDLGVNPADDGKVIRCVFPELTEERRKEYIKISRHK
CCEEEEEECCCCCHHHHHHHHHHHCCCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHC
AEEGRVAVRNLRRTAKQHLERLEKDGEVGQDDLTGAEKRLDGLTKKHTDAIDEMLKHKEA
CHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ELLEV
HHHCC
>Mature Secondary Structure
MINDILNEADGKMDKSVEATREEFAAIRAGRVNPSMFNKIVVDYYGSPTPLQQLASFTAP
CCHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCHHHHHHHCCCC
EARIILIAPYDQGAMHNILKAIRDSDLGVNPADDGKVIRCVFPELTEERRKEYIKISRHK
CCEEEEEECCCCCHHHHHHHHHHHCCCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHC
AEEGRVAVRNLRRTAKQHLERLEKDGEVGQDDLTGAEKRLDGLTKKHTDAIDEMLKHKEA
CHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ELLEV
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA