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The map label for this gene is potC [H]

Identifier: 119717450

GI number: 119717450

Start: 3427386

End: 3428255

Strand: Reverse

Name: potC [H]

Synonym: Noca_3226

Alternate gene names: 119717450

Gene position: 3428255-3427386 (Counterclockwise)

Preceding gene: 119717451

Following gene: 119717448

Centisome position: 68.76

GC content: 67.47

Gene sequence:

>870_bases
ATGGCCACGAGCACGCAGCTGCCCGCCCCCAGCCGCACCAGGCGCAGCGGCCGCGACCGGCCGCCGGTCGGCCGCTGGCT
GGCCGATCACATGGTCCTGTTCATCGGGATCCTGGTGCTCGTCTACATGTTCGTACCGATCGGCTACATCTTCGCGCTGT
CGTTCAACCAACCCACCGGACGCTCCGCGACCGCGGAGTTCGAGTCGTTCACCTGGAGCAACTGGACCTCGATCTGCGAG
CCCGAGGGCCTGTGCGACTCACTCCAGCTGAGCATCGCCGTGAGCCTGACCGCCACCGTGCTGGCCACCGTGCTGGGCAC
GCTGATGGCGTTCGCCCTGGTGCGGCACTCCTTCCGGGGCCGGGCGGCGTCGAACCTCCTGATCTTCCTGCCGATGGCGA
CCCCGGAGGTCGTCATGGGGTCCTCGTTGCTGGCGATGTTCGTCTCGATCGGGATGGACGGCGCCCTCGGCTTCGCCACG
CTCGTGATCGCCCACGTGCTGTTCTGCCTGTCGTTCGTGGTCGTGACCGTCAAGGCGAGGCTCGTCGGCATGGACGCCCG
GTTGGAGCAGGCGGCGATGGACCTCTACGCGAACGAGTGGCAGACCTTCCGGCTGGTCACCCTGCCGCTGGCGATGCCGG
GCATCGTCGCGGCGGCGCTGCTGTCCTTCTCGCTGTCCTTCGACGACTTCATCGTCTCGAACTTCACGGCCGGCCAGTCG
GTCACCTTCCCGATCTTCGTCTACGGCAGCAAGCTGAAGGACTTCCCGCCGCAGCTGTTCGTCGTGGGGTCGATCATGTT
CCTGGTGTCGTTCGTCTTCGTGGTCGCCGGCGAGCTGTGGCGGCGCCGTCGGTCGGTCGGCCTGGGCTGA

Upstream 100 bases:

>100_bases
ACTACCCGCTGGCGGCCAGCCTGTCGCTGACCTTGATGGCGATCGTCGTCGTGATGGTCGTCGTCTATGTCCGGCGGGCC
GGCACCGAGGAGCTGGTCTG

Downstream 100 bases:

>100_bases
CCGACCGGCAGGCGCTGGACGCCGTCAGACCAGCGTGCCCGCCTTGTCGAGGACCACGCGCAGGATCTGCTCCATCTCGT
CGAAGTGCGACTGCTCGCAG

Product: binding-protein-dependent transport systems inner membrane component

Products: Phosphate; putrescine [Cytoplasm]; ADP; spermidine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 289; Mature: 288

Protein sequence:

>289_residues
MATSTQLPAPSRTRRSGRDRPPVGRWLADHMVLFIGILVLVYMFVPIGYIFALSFNQPTGRSATAEFESFTWSNWTSICE
PEGLCDSLQLSIAVSLTATVLATVLGTLMAFALVRHSFRGRAASNLLIFLPMATPEVVMGSSLLAMFVSIGMDGALGFAT
LVIAHVLFCLSFVVVTVKARLVGMDARLEQAAMDLYANEWQTFRLVTLPLAMPGIVAAALLSFSLSFDDFIVSNFTAGQS
VTFPIFVYGSKLKDFPPQLFVVGSIMFLVSFVFVVAGELWRRRRSVGLG

Sequences:

>Translated_289_residues
MATSTQLPAPSRTRRSGRDRPPVGRWLADHMVLFIGILVLVYMFVPIGYIFALSFNQPTGRSATAEFESFTWSNWTSICE
PEGLCDSLQLSIAVSLTATVLATVLGTLMAFALVRHSFRGRAASNLLIFLPMATPEVVMGSSLLAMFVSIGMDGALGFAT
LVIAHVLFCLSFVVVTVKARLVGMDARLEQAAMDLYANEWQTFRLVTLPLAMPGIVAAALLSFSLSFDDFIVSNFTAGQS
VTFPIFVYGSKLKDFPPQLFVVGSIMFLVSFVFVVAGELWRRRRSVGLG
>Mature_288_residues
ATSTQLPAPSRTRRSGRDRPPVGRWLADHMVLFIGILVLVYMFVPIGYIFALSFNQPTGRSATAEFESFTWSNWTSICEP
EGLCDSLQLSIAVSLTATVLATVLGTLMAFALVRHSFRGRAASNLLIFLPMATPEVVMGSSLLAMFVSIGMDGALGFATL
VIAHVLFCLSFVVVTVKARLVGMDARLEQAAMDLYANEWQTFRLVTLPLAMPGIVAAALLSFSLSFDDFIVSNFTAGQSV
TFPIFVYGSKLKDFPPQLFVVGSIMFLVSFVFVVAGELWRRRRSVGLG

Specific function: Required for the activity of the bacterial periplasmic transport system of putrescine and spermidine [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787368, Length=223, Percent_Identity=36.7713004484305, Blast_Score=146, Evalue=1e-36,
Organism=Escherichia coli, GI1787081, Length=207, Percent_Identity=32.8502415458937, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1787714, Length=221, Percent_Identity=38.0090497737557, Blast_Score=100, Evalue=8e-23,
Organism=Escherichia coli, GI1788764, Length=188, Percent_Identity=30.8510638297872, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1786980, Length=190, Percent_Identity=32.1052631578947, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 31530; Mature: 31398

Theoretical pI: Translated: 8.87; Mature: 8.87

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATSTQLPAPSRTRRSGRDRPPVGRWLADHMVLFIGILVLVYMFVPIGYIFALSFNQPTG
CCCCCCCCCCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCC
RSATAEFESFTWSNWTSICEPEGLCDSLQLSIAVSLTATVLATVLGTLMAFALVRHSFRG
CCCCHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
RAASNLLIFLPMATPEVVMGSSLLAMFVSIGMDGALGFATLVIAHVLFCLSFVVVTVKAR
CCCCCEEEEEECCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LVGMDARLEQAAMDLYANEWQTFRLVTLPLAMPGIVAAALLSFSLSFDDFIVSNFTAGQS
HHCCHHHHHHHHHHHHHCCCCEEEEEEECHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCC
VTFPIFVYGSKLKDFPPQLFVVGSIMFLVSFVFVVAGELWRRRRSVGLG
EEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
ATSTQLPAPSRTRRSGRDRPPVGRWLADHMVLFIGILVLVYMFVPIGYIFALSFNQPTG
CCCCCCCCCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCC
RSATAEFESFTWSNWTSICEPEGLCDSLQLSIAVSLTATVLATVLGTLMAFALVRHSFRG
CCCCHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
RAASNLLIFLPMATPEVVMGSSLLAMFVSIGMDGALGFATLVIAHVLFCLSFVVVTVKAR
CCCCCEEEEEECCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LVGMDARLEQAAMDLYANEWQTFRLVTLPLAMPGIVAAALLSFSLSFDDFIVSNFTAGQS
HHCCHHHHHHHHHHHHHCCCCEEEEEEECHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCC
VTFPIFVYGSKLKDFPPQLFVVGSIMFLVSFVFVVAGELWRRRRSVGLG
EEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Putrescine [Periplasm]; H2O; ATP; spermidine [Periplasm] [C]

Specific reaction: ATP + putrescine [Periplasm] + H2O = ADP + phosphate + putrescine [Cytoplasm] ATP + spermidine [Periplasm] + H2O = ADP + phosphate + spermidine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]