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The map label for this gene is nusA [H]

Identifier: 119717416

GI number: 119717416

Start: 3391878

End: 3392861

Strand: Reverse

Name: nusA [H]

Synonym: Noca_3192

Alternate gene names: 119717416

Gene position: 3392861-3391878 (Counterclockwise)

Preceding gene: 119717417

Following gene: 119717415

Centisome position: 68.05

GC content: 70.33

Gene sequence:

>984_bases
ATGGACATCGACATGAGCATCCTGCGGATGCTCGAGCGGGAGAAGGAGATCTCCTTCGACGTGCTCGTCGAGGCGATCGA
GCAGGCCCTGCTCACGGCGTACCACAAGTCGCCGGGTGCGCACGAGCAGGCGCGCGTCGTGCTGGACCGCAAGAGCGGCC
ACGTGACCGTGCTCGCCTCGGAGGTCGACGAGGAGGGCAATGCCGTCGGCGAGTACGACGACACCCCGGCCGGGTTCGGC
CGGATCGCGGCGACGACGGCGAAGCAGATCATGCTCCAGCGGCTGCGCGACGCCGAGGACGACGTCCGGTTCGGTGAGTT
CTCCGGCAAGGAGGGCGACATCATCTCGGGGATCATCCAGCAGGGCCGCAACCCCGACGACGTGATGGTCGACCTCGGCA
AGCTCGAGGCGCTGCTGCCGGTCGGCGAGCGGGTGCCGGGGGAGCGCTACGACCACGGCACCCGGATCAAGTGCCTGGTC
GTGTCGGTCCGCAAGGGCATGCGCGGGCCGCAGATCACGCTGTCGCGCTCGCACCCGAACCTCGTCAAGAAGCTGTTCGC
GCTGGAGGTGCCCGAGATCGCCGACGGCACGGTCGAGATCGCCGCGATCGCCCGCGAGGCCGGGCACCGCACCAAGCTCG
CGGTCCGCTCGACCGTGCCCGGGGTGAACGCCAAGGGCGCCTGCATCGGCCCGATGGGCTCGCGCGTGCGTGCGGTGATG
TCCGAGCTGCACGGCGAGAAGATCGACATCGTCGACTGGTCCGAGGACCCCGCCGAGATGGTCGCGCACGCGCTCTCACC
GGCGCGGGTCACGTCCGTCGAGATCGTCGACGCGGCCGCGAAGTCCGCGCGCGTCGTGGTGCCGGACTTCCAGCTCTCCC
TCGCGATCGGCAAGGAGGGCCAGAACGCCCGCCTGGCCGCCCGCCTCACCGGCTGGCGCATCGATATCAGGAGCGACGAG
GCCGAAGCCGGCAGCGACGCCTGA

Upstream 100 bases:

>100_bases
AGGTGAAGAAGGCGCTGGTGCAGGTCGAGTTCAACCGGCCCACGGACGGGCCGGGCGATGACGGAGACGACGGCGGAGAC
GACGAGGCGGGGGAGGCCTG

Downstream 100 bases:

>100_bases
GGAGCGGCGGGATCGCGGCACCACGGGTCCCCGGTTCGATAAGGGTGGCCCGATCGCGGTAGGGTTGTCGCCAGTGGCGC
GTGAACACATCCCTTCTGCA

Product: transcription elongation factor NusA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 327; Mature: 327

Protein sequence:

>327_residues
MDIDMSILRMLEREKEISFDVLVEAIEQALLTAYHKSPGAHEQARVVLDRKSGHVTVLASEVDEEGNAVGEYDDTPAGFG
RIAATTAKQIMLQRLRDAEDDVRFGEFSGKEGDIISGIIQQGRNPDDVMVDLGKLEALLPVGERVPGERYDHGTRIKCLV
VSVRKGMRGPQITLSRSHPNLVKKLFALEVPEIADGTVEIAAIAREAGHRTKLAVRSTVPGVNAKGACIGPMGSRVRAVM
SELHGEKIDIVDWSEDPAEMVAHALSPARVTSVEIVDAAAKSARVVVPDFQLSLAIGKEGQNARLAARLTGWRIDIRSDE
AEAGSDA

Sequences:

>Translated_327_residues
MDIDMSILRMLEREKEISFDVLVEAIEQALLTAYHKSPGAHEQARVVLDRKSGHVTVLASEVDEEGNAVGEYDDTPAGFG
RIAATTAKQIMLQRLRDAEDDVRFGEFSGKEGDIISGIIQQGRNPDDVMVDLGKLEALLPVGERVPGERYDHGTRIKCLV
VSVRKGMRGPQITLSRSHPNLVKKLFALEVPEIADGTVEIAAIAREAGHRTKLAVRSTVPGVNAKGACIGPMGSRVRAVM
SELHGEKIDIVDWSEDPAEMVAHALSPARVTSVEIVDAAAKSARVVVPDFQLSLAIGKEGQNARLAARLTGWRIDIRSDE
AEAGSDA
>Mature_327_residues
MDIDMSILRMLEREKEISFDVLVEAIEQALLTAYHKSPGAHEQARVVLDRKSGHVTVLASEVDEEGNAVGEYDDTPAGFG
RIAATTAKQIMLQRLRDAEDDVRFGEFSGKEGDIISGIIQQGRNPDDVMVDLGKLEALLPVGERVPGERYDHGTRIKCLV
VSVRKGMRGPQITLSRSHPNLVKKLFALEVPEIADGTVEIAAIAREAGHRTKLAVRSTVPGVNAKGACIGPMGSRVRAVM
SELHGEKIDIVDWSEDPAEMVAHALSPARVTSVEIVDAAAKSARVVVPDFQLSLAIGKEGQNARLAARLTGWRIDIRSDE
AEAGSDA

Specific function: Participates in both the termination and antitermination of transcription. Interacts with RNA polymerase and binds RNA [H]

COG id: COG0195

COG function: function code K; Transcription elongation factor

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 S1 motif domain [H]

Homologues:

Organism=Escherichia coli, GI1789560, Length=337, Percent_Identity=35.0148367952522, Blast_Score=202, Evalue=2e-53,

Paralogues:

None

Copy number: 340 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1612 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 1,800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004087
- InterPro:   IPR015946
- InterPro:   IPR009019
- InterPro:   IPR004088
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR003029
- InterPro:   IPR022967
- InterPro:   IPR013735
- InterPro:   IPR010213 [H]

Pfam domain/function: PF08529 NusA_N [H]

EC number: NA

Molecular weight: Translated: 35339; Mature: 35339

Theoretical pI: Translated: 5.18; Mature: 5.18

Prosite motif: PS50084 KH_TYPE_1 ; PS50126 S1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDIDMSILRMLEREKEISFDVLVEAIEQALLTAYHKSPGAHEQARVVLDRKSGHVTVLAS
CCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCEEEEEE
EVDEEGNAVGEYDDTPAGFGRIAATTAKQIMLQRLRDAEDDVRFGEFSGKEGDIISGIIQ
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEECCCCCCCCHHHHHHHH
QGRNPDDVMVDLGKLEALLPVGERVPGERYDHGTRIKCLVVSVRKGMRGPQITLSRSHPN
CCCCCHHHHEEHHHHHHHHCCCCCCCCCCCCCCCEEEEEEEEHHCCCCCCEEEEECCCHH
LVKKLFALEVPEIADGTVEIAAIAREAGHRTKLAVRSTVPGVNAKGACIGPMGSRVRAVM
HHHHHHHHCCCCCCCCCCHHHHHHHHCCCCEEEEEECCCCCCCCCCCEECCCHHHHHHHH
SELHGEKIDIVDWSEDPAEMVAHALSPARVTSVEIVDAAAKSARVVVPDFQLSLAIGKEG
HHHCCCEEEEEECCCCHHHHHHHHCCCCCEEEEHHHHHHCCCCEEEECCCEEEEEECCCC
QNARLAARLTGWRIDIRSDEAEAGSDA
CCCEEEEEEECEEEEEECCCCCCCCCC
>Mature Secondary Structure
MDIDMSILRMLEREKEISFDVLVEAIEQALLTAYHKSPGAHEQARVVLDRKSGHVTVLAS
CCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCEEEEEE
EVDEEGNAVGEYDDTPAGFGRIAATTAKQIMLQRLRDAEDDVRFGEFSGKEGDIISGIIQ
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEECCCCCCCCHHHHHHHH
QGRNPDDVMVDLGKLEALLPVGERVPGERYDHGTRIKCLVVSVRKGMRGPQITLSRSHPN
CCCCCHHHHEEHHHHHHHHCCCCCCCCCCCCCCCEEEEEEEEHHCCCCCCEEEEECCCHH
LVKKLFALEVPEIADGTVEIAAIAREAGHRTKLAVRSTVPGVNAKGACIGPMGSRVRAVM
HHHHHHHHCCCCCCCCCCHHHHHHHHCCCCEEEEEECCCCCCCCCCCEECCCHHHHHHHH
SELHGEKIDIVDWSEDPAEMVAHALSPARVTSVEIVDAAAKSARVVVPDFQLSLAIGKEG
HHHCCCEEEEEECCCCHHHHHHHHCCCCCEEEEHHHHHHCCCCEEEECCCEEEEEECCCC
QNARLAARLTGWRIDIRSDEAEAGSDA
CCCEEEEEEECEEEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]