Click here to switch to the map view.

The map label for this gene is paaE [H]

Identifier: 119717379

GI number: 119717379

Start: 3356096

End: 3357157

Strand: Reverse

Name: paaE [H]

Synonym: Noca_3155

Alternate gene names: 119717379

Gene position: 3357157-3356096 (Counterclockwise)

Preceding gene: 119717380

Following gene: 119717378

Centisome position: 67.33

GC content: 72.98

Gene sequence:

>1062_bases
GTGCCGGCCACCTTCCACTCGCTGCGGGTCGCGGCGATCGACGAGCTCACCGACGACGCGGTCGCGCTCACCTTCGACGT
CCCGACGCCGCTGGCCGCTGAGTTCACCTTCGCCCCGGGCCAGCACGTCTCCATCCGCGGGGGCGATGACGTGCGCCGGT
CCTACTCCATCTGCACCACGCCCTCCTCGGGGGTCCTGCGGATCGGCGTGAAGCGGCTGCCCGGCGGCGCGTTCAGCGAG
GGCGTCCTCGGGAGCCTGCGGGTGGGGGACGACCTGGAGGTGATGACCCCGGCGGGCCGGTTCACGGCCGCGGTCGACCC
CAGCGCTCGCCGTACCCACGTCGCGATCGCGGCCGGCTCCGGCATCACCCCGGTGCTCTCGATCGTCGCGGCGCTCCTCG
AGGAGGAGCCGCACTCCTCGGTGCTGCTGCTCTACGCCAACCGCACGCACCGGTCGGTGATGTTCCTCGACGAGGTCCAC
GACCTCAAGGACCTGTTCCCGACCCGCCTGCAGGTCGTGCACGTGCTCTCCCGGGAGCAGCAGGAGGTGGAGCTGCTCTC
CGGGCGCCTCGACGGCGATCGCCTACGACGGATCCTGGCCGCGCTGATGCCGGCCGAGGAGGTCGACCAGTGGTACCTGT
GCGGCCCGCAGCAGCTCGTGACCGAGCTGCGGGCGACCCTCACGACCCTCGGGGTGGACCCCGCGTCCGTGCACAGCGAG
CTCTTCCACGCCGACCCCGTGCAGCGGGCGCCGGTCTCGGTCCTCGACGGGTCACCCGAGGGCGCGGCGCGGGTGACCGT
CCGCCTCGACGGGCGCTCGTCCGACCTGGACCTGCGGCCCGACGGCGTGTCGGTCCTCGAGGCTGCGCTGCGGGTGCGCT
CGGACCTGCCGTTCGCCTGCAAGGGGGGAGTCTGCGGGACCTGCCGCGCCCGGCTGGTCGAGGGCACCGTCGCCATGGAC
GCCAACTACGCGCTCGAGCCGGACGAGATCGACCGGGGCTACGTGCTCACCTGTCAGTCCCACCCCACCTCCGAGCGGGT
GGTCCTCGACTACGACGGCTGA

Upstream 100 bases:

>100_bases
CGAGCCGCTTCGGGTCGACCGCCTGCAAGTCGCTGTGGGTGTGTCGCAGCTGCCGGGAGCCGTTCGACCACTTCAAGGCC
CTCTGATGGGGCGGATCTGA

Downstream 100 bases:

>100_bases
CCGCCGGGGTCCTAGGGTCGTCCTATGCAGACTCGCACCCTCGGCAGCAGTGGACTCAGGATCTCGGAGATCGCGTACGG
CAACTGGCTCACGCACGGAT

Product: phenylacetate-CoA oxygenase/reductase subunit PaaK

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 353; Mature: 352

Protein sequence:

>353_residues
MPATFHSLRVAAIDELTDDAVALTFDVPTPLAAEFTFAPGQHVSIRGGDDVRRSYSICTTPSSGVLRIGVKRLPGGAFSE
GVLGSLRVGDDLEVMTPAGRFTAAVDPSARRTHVAIAAGSGITPVLSIVAALLEEEPHSSVLLLYANRTHRSVMFLDEVH
DLKDLFPTRLQVVHVLSREQQEVELLSGRLDGDRLRRILAALMPAEEVDQWYLCGPQQLVTELRATLTTLGVDPASVHSE
LFHADPVQRAPVSVLDGSPEGAARVTVRLDGRSSDLDLRPDGVSVLEAALRVRSDLPFACKGGVCGTCRARLVEGTVAMD
ANYALEPDEIDRGYVLTCQSHPTSERVVLDYDG

Sequences:

>Translated_353_residues
MPATFHSLRVAAIDELTDDAVALTFDVPTPLAAEFTFAPGQHVSIRGGDDVRRSYSICTTPSSGVLRIGVKRLPGGAFSE
GVLGSLRVGDDLEVMTPAGRFTAAVDPSARRTHVAIAAGSGITPVLSIVAALLEEEPHSSVLLLYANRTHRSVMFLDEVH
DLKDLFPTRLQVVHVLSREQQEVELLSGRLDGDRLRRILAALMPAEEVDQWYLCGPQQLVTELRATLTTLGVDPASVHSE
LFHADPVQRAPVSVLDGSPEGAARVTVRLDGRSSDLDLRPDGVSVLEAALRVRSDLPFACKGGVCGTCRARLVEGTVAMD
ANYALEPDEIDRGYVLTCQSHPTSERVVLDYDG
>Mature_352_residues
PATFHSLRVAAIDELTDDAVALTFDVPTPLAAEFTFAPGQHVSIRGGDDVRRSYSICTTPSSGVLRIGVKRLPGGAFSEG
VLGSLRVGDDLEVMTPAGRFTAAVDPSARRTHVAIAAGSGITPVLSIVAALLEEEPHSSVLLLYANRTHRSVMFLDEVHD
LKDLFPTRLQVVHVLSREQQEVELLSGRLDGDRLRRILAALMPAEEVDQWYLCGPQQLVTELRATLTTLGVDPASVHSEL
FHADPVQRAPVSVLDGSPEGAARVTVRLDGRSSDLDLRPDGVSVLEAALRVRSDLPFACKGGVCGTCRARLVEGTVAMDA
NYALEPDEIDRGYVLTCQSHPTSERVVLDYDG

Specific function: May be part of a multicomponent oxygenase involved in phenylacetyl-CoA hydroxylation [H]

COG id: COG1018

COG function: function code C; Flavodoxin reductases (ferredoxin-NADPH reductases) family 1

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding FR-type domain [H]

Homologues:

Organism=Homo sapiens, GI284448553, Length=246, Percent_Identity=23.1707317073171, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI6552328, Length=246, Percent_Identity=23.1707317073171, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI193794826, Length=246, Percent_Identity=23.1707317073171, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI284448551, Length=246, Percent_Identity=23.1707317073171, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI4503327, Length=246, Percent_Identity=23.1707317073171, Blast_Score=69, Evalue=5e-12,
Organism=Escherichia coli, GI1787658, Length=354, Percent_Identity=43.7853107344633, Blast_Score=298, Evalue=5e-82,
Organism=Escherichia coli, GI1787098, Length=317, Percent_Identity=28.7066246056782, Blast_Score=105, Evalue=4e-24,
Organism=Escherichia coli, GI1788104, Length=358, Percent_Identity=27.9329608938547, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1788903, Length=194, Percent_Identity=30.9278350515464, Blast_Score=75, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI17563926, Length=213, Percent_Identity=27.6995305164319, Blast_Score=72, Evalue=5e-13,
Organism=Saccharomyces cerevisiae, GI6322146, Length=206, Percent_Identity=28.1553398058252, Blast_Score=72, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6323510, Length=220, Percent_Identity=27.7272727272727, Blast_Score=69, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006058
- InterPro:   IPR012675
- InterPro:   IPR017927
- InterPro:   IPR001041
- InterPro:   IPR001709
- InterPro:   IPR008333
- InterPro:   IPR001433
- InterPro:   IPR011884
- InterPro:   IPR001221
- InterPro:   IPR017938 [H]

Pfam domain/function: PF00970 FAD_binding_6; PF00111 Fer2; PF00175 NAD_binding_1 [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 37994; Mature: 37862

Theoretical pI: Translated: 4.84; Mature: 4.84

Prosite motif: PS00197 2FE2S_FER_1 ; PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPATFHSLRVAAIDELTDDAVALTFDVPTPLAAEFTFAPGQHVSIRGGDDVRRSYSICTT
CCCCHHHEEEHHHHHCCCCEEEEEEECCCCCCEEEEECCCCEEEEECCCHHHHCEEEEEC
PSSGVLRIGVKRLPGGAFSEGVLGSLRVGDDLEVMTPAGRFTAAVDPSARRTHVAIAAGS
CCCCEEEEEHHHCCCCCCCCCCEEEEECCCCCEEECCCCCEEEEECCCCCCEEEEEEECC
GITPVLSIVAALLEEEPHSSVLLLYANRTHRSVMFLDEVHDLKDLFPTRLQVVHVLSREQ
CCHHHHHHHHHHHCCCCCCCEEEEEECCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHCCH
QEVELLSGRLDGDRLRRILAALMPAEEVDQWYLCGPQQLVTELRATLTTLGVDPASVHSE
HHHHHHHCCCCHHHHHHHHHHHCCHHHCCCEEEECHHHHHHHHHHHHHHCCCCHHHHHHH
LFHADPVQRAPVSVLDGSPEGAARVTVRLDGRSSDLDLRPDGVSVLEAALRVRSDLPFAC
HHCCCCCCCCCEEEECCCCCCCEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHCCCCEEE
KGGVCGTCRARLVEGTVAMDANYALEPDEIDRGYVLTCQSHPTSERVVLDYDG
CCCCCHHHHHHHCCCEEEECCCCCCCCCCCCCCEEEEECCCCCCCEEEEEECC
>Mature Secondary Structure 
PATFHSLRVAAIDELTDDAVALTFDVPTPLAAEFTFAPGQHVSIRGGDDVRRSYSICTT
CCCHHHEEEHHHHHCCCCEEEEEEECCCCCCEEEEECCCCEEEEECCCHHHHCEEEEEC
PSSGVLRIGVKRLPGGAFSEGVLGSLRVGDDLEVMTPAGRFTAAVDPSARRTHVAIAAGS
CCCCEEEEEHHHCCCCCCCCCCEEEEECCCCCEEECCCCCEEEEECCCCCCEEEEEEECC
GITPVLSIVAALLEEEPHSSVLLLYANRTHRSVMFLDEVHDLKDLFPTRLQVVHVLSREQ
CCHHHHHHHHHHHCCCCCCCEEEEEECCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHCCH
QEVELLSGRLDGDRLRRILAALMPAEEVDQWYLCGPQQLVTELRATLTTLGVDPASVHSE
HHHHHHHCCCCHHHHHHHHHHHCCHHHCCCEEEECHHHHHHHHHHHHHHCCCCHHHHHHH
LFHADPVQRAPVSVLDGSPEGAARVTVRLDGRSSDLDLRPDGVSVLEAALRVRSDLPFAC
HHCCCCCCCCCEEEECCCCCCCEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHCCCCEEE
KGGVCGTCRARLVEGTVAMDANYALEPDEIDRGYVLTCQSHPTSERVVLDYDG
CCCCCHHHHHHHCCCEEEECCCCCCCCCCCCCCEEEEECCCCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: FAD [C]

Metal ions: Iron-Sulfur [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9748275; 9097039; 9278503; 10766858 [H]