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The map label for this gene is rsmH

Identifier: 119717295

GI number: 119717295

Start: 3270719

End: 3271678

Strand: Reverse

Name: rsmH

Synonym: Noca_3071

Alternate gene names: 119717295

Gene position: 3271678-3270719 (Counterclockwise)

Preceding gene: 119717296

Following gene: 119717294

Centisome position: 65.62

GC content: 75.21

Gene sequence:

>960_bases
ATGAGCGGCCCCTCCCACGTCCCGGTCCTGCTCGACCGGGTCGTCGCCCTGCTGGCCCCGCCGCTCGAGCGGGAGGGCTC
CGTCCTGGTCGACGCCACCCTGGGCCTCGGCGGCCACACCGAGGCGGTGCTCACCCGCTTCGACCTGGCGCGCGTGGTCG
GCATCGACCGCGACCCGGAGGCGCTCGCGCTCGCGGGCCGGCGGCTGGCGCCGTTCGGGGACCGCTTCACCGGGGTGCAC
GCCGTGTACGACGAGCTCCCGGACGTGCTGGCCCGGCTCGGCCTGGACGCGGTGGACGCCGTGCTCTTCGACCTCGGCGT
CTCCTCGATGCAGCTCGACGTGCGCGAGCGCGGCTTCGCGTACGCCGAGGATGCCCCCCTCGACATGCGGATGGACGGCA
GCACCGGCCCGACGGCGGCCGACGTGCTCAACACCTACGCCGCCGCCGACCTGGCCCGGATCCTGCGGGAGTACGGCGAG
GAGCGGTTCGCCCGCAAGATCGCGGCCGCCGTGGTGCGCGAGCGGGCCAAGGAGCCGTTCACCCGGTCCGGTCGGCTGGT
CGAGCTCCTCTACGCGGAGATCCCAGCGCCGGCCCGGCGTACCGGCGGCCACCCCGCCAAGCGCACCTTCCAGGCGCTGC
GGATGGAGGTCAACGACGAGCTCGCCGTGCTGCGACGGGCGATCCCCGCCGCCATCGACGCCATCGGCGTGGGCGGCCGG
GTCGTCGTCGAGTCCTACCACTCGCTGGAGGACCGGCTGGTCAAGCAGGCGTTCGTGGCCGCCTCCCGGCTCGACGTCCC
CGAGGACCTGCCGTTCGTGCCCGCCGGCCACGAGCCGGCCCTGCGCCTGGTCACCCGGGGCGCCGAGAAGGCGGGCCCCG
AGGAGATCGCCCTGAACCCGCGCGCCGCCTCGGTCCGGCTGCGCGCGATCGAGCGCACGAGCAAGGGAGCAGCAGCATGA

Upstream 100 bases:

>100_bases
GCCCGCGACGCGGCGACCGTGATGGCGTTCTCCGCCGCGACCTCGCTCGGGGTGGCCCTCGCGTTCCTGCTCCTCGCACT
GCTGGCGCGTCAGGTCTGAC

Downstream 100 bases:

>100_bases
GCAGTCCGATGCCCCAGGCCCGCTCGCGGATGCCGCGGATCGCCGAGCGTGCCGTCGAGCGGGCCCGGCTCACCGTCGTC
CCACGCACCCGTGCGCAGGC

Product: S-adenosyl-methyltransferase MraW

Products: NA

Alternate protein names: 16S rRNA m(4)C1402 methyltransferase; rRNA (cytosine-N(4)-)-methyltransferase RsmH

Number of amino acids: Translated: 319; Mature: 318

Protein sequence:

>319_residues
MSGPSHVPVLLDRVVALLAPPLEREGSVLVDATLGLGGHTEAVLTRFDLARVVGIDRDPEALALAGRRLAPFGDRFTGVH
AVYDELPDVLARLGLDAVDAVLFDLGVSSMQLDVRERGFAYAEDAPLDMRMDGSTGPTAADVLNTYAAADLARILREYGE
ERFARKIAAAVVRERAKEPFTRSGRLVELLYAEIPAPARRTGGHPAKRTFQALRMEVNDELAVLRRAIPAAIDAIGVGGR
VVVESYHSLEDRLVKQAFVAASRLDVPEDLPFVPAGHEPALRLVTRGAEKAGPEEIALNPRAASVRLRAIERTSKGAAA

Sequences:

>Translated_319_residues
MSGPSHVPVLLDRVVALLAPPLEREGSVLVDATLGLGGHTEAVLTRFDLARVVGIDRDPEALALAGRRLAPFGDRFTGVH
AVYDELPDVLARLGLDAVDAVLFDLGVSSMQLDVRERGFAYAEDAPLDMRMDGSTGPTAADVLNTYAAADLARILREYGE
ERFARKIAAAVVRERAKEPFTRSGRLVELLYAEIPAPARRTGGHPAKRTFQALRMEVNDELAVLRRAIPAAIDAIGVGGR
VVVESYHSLEDRLVKQAFVAASRLDVPEDLPFVPAGHEPALRLVTRGAEKAGPEEIALNPRAASVRLRAIERTSKGAAA
>Mature_318_residues
SGPSHVPVLLDRVVALLAPPLEREGSVLVDATLGLGGHTEAVLTRFDLARVVGIDRDPEALALAGRRLAPFGDRFTGVHA
VYDELPDVLARLGLDAVDAVLFDLGVSSMQLDVRERGFAYAEDAPLDMRMDGSTGPTAADVLNTYAAADLARILREYGEE
RFARKIAAAVVRERAKEPFTRSGRLVELLYAEIPAPARRTGGHPAKRTFQALRMEVNDELAVLRRAIPAAIDAIGVGGRV
VVESYHSLEDRLVKQAFVAASRLDVPEDLPFVPAGHEPALRLVTRGAEKAGPEEIALNPRAASVRLRAIERTSKGAAA

Specific function: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA

COG id: COG0275

COG function: function code M; Predicted S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. RsmH family

Homologues:

Organism=Homo sapiens, GI165377209, Length=340, Percent_Identity=35.8823529411765, Blast_Score=189, Evalue=2e-48,
Organism=Homo sapiens, GI165377202, Length=203, Percent_Identity=41.3793103448276, Blast_Score=147, Evalue=2e-35,
Organism=Escherichia coli, GI1786270, Length=319, Percent_Identity=40.7523510971787, Blast_Score=207, Evalue=6e-55,
Organism=Drosophila melanogaster, GI62472493, Length=334, Percent_Identity=36.8263473053892, Blast_Score=167, Evalue=9e-42,
Organism=Drosophila melanogaster, GI28571637, Length=334, Percent_Identity=36.8263473053892, Blast_Score=167, Evalue=9e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RSMH_NOCSJ (A1SL88)

Other databases:

- EMBL:   CP000509
- RefSeq:   YP_924260.1
- ProteinModelPortal:   A1SL88
- STRING:   A1SL88
- GeneID:   4600188
- GenomeReviews:   CP000509_GR
- KEGG:   nca:Noca_3071
- eggNOG:   COG0275
- HOGENOM:   HBG302779
- OMA:   PQLDDPE
- PhylomeDB:   A1SL88
- BioCyc:   NSP35761:NOCA_3071-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01007
- InterPro:   IPR002903
- PANTHER:   PTHR11265
- PIRSF:   PIRSF004486
- TIGRFAMs:   TIGR00006

Pfam domain/function: PF01795 Methyltransf_5

EC number: NA

Molecular weight: Translated: 34284; Mature: 34152

Theoretical pI: Translated: 6.01; Mature: 6.01

Prosite motif: NA

Important sites: BINDING 56-56 BINDING 90-90 BINDING 104-104 BINDING 111-111

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGPSHVPVLLDRVVALLAPPLEREGSVLVDATLGLGGHTEAVLTRFDLARVVGIDRDPE
CCCCCCHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCH
ALALAGRRLAPFGDRFTGVHAVYDELPDVLARLGLDAVDAVLFDLGVSSMQLDVRERGFA
HHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCHHHHHHHHCCCE
YAEDAPLDMRMDGSTGPTAADVLNTYAAADLARILREYGEERFARKIAAAVVRERAKEPF
ECCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
TRSGRLVELLYAEIPAPARRTGGHPAKRTFQALRMEVNDELAVLRRAIPAAIDAIGVGGR
CCCCCHHHHHHHHCCCCHHHCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCH
VVVESYHSLEDRLVKQAFVAASRLDVPEDLPFVPAGHEPALRLVTRGAEKAGPEEIALNP
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHCHHHCCCCCEEECC
RAASVRLRAIERTSKGAAA
CHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
SGPSHVPVLLDRVVALLAPPLEREGSVLVDATLGLGGHTEAVLTRFDLARVVGIDRDPE
CCCCCHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCH
ALALAGRRLAPFGDRFTGVHAVYDELPDVLARLGLDAVDAVLFDLGVSSMQLDVRERGFA
HHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCHHHHHHHHCCCE
YAEDAPLDMRMDGSTGPTAADVLNTYAAADLARILREYGEERFARKIAAAVVRERAKEPF
ECCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
TRSGRLVELLYAEIPAPARRTGGHPAKRTFQALRMEVNDELAVLRRAIPAAIDAIGVGGR
CCCCCHHHHHHHHCCCCHHHCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCH
VVVESYHSLEDRLVKQAFVAASRLDVPEDLPFVPAGHEPALRLVTRGAEKAGPEEIALNP
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHCHHHCCCCCEEECC
RAASVRLRAIERTSKGAAA
CHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA