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The map label for this gene is lspA [H]

Identifier: 119717277

GI number: 119717277

Start: 3252101

End: 3252697

Strand: Reverse

Name: lspA [H]

Synonym: Noca_3053

Alternate gene names: 119717277

Gene position: 3252697-3252101 (Counterclockwise)

Preceding gene: 119717278

Following gene: 119717276

Centisome position: 65.24

GC content: 72.7

Gene sequence:

>597_bases
ATGCAAGCAGCGCGAGGAACGTCGCTGACCGGCGACCAGTCTGATCCGGCCCGGCCCCGACCGACCCGACCGCGACGGCA
CCGCCTGCTGGCCGTCTACGCCGCGGTCGCGCTCACGGCGTACGCCGTCGACGTCGGCTCGAAGATCCTCGCCGTCGACC
GGCTGAGCGGGCGCCCCGACGTCCAGCTCGTCGGTGACCTGTTCCAGCTCCACCTGGTGCGCAACCCCGGGGCGGCCTTC
AGCACCGGTACCGCCTACACCGAGGTCCTCAGCGTGGTCGCGATCATCGCGGTCCTGGTGCTGCTCTATCTCGCCCGCCG
GATCGGGACCGTCGGCTGGGCGGTCTCGCTGGGCCTGCTGCTCGCCGGGGTCGCCGGCAACCTCACCGACCGGCTGGTGC
GCTCGCCCGGCCCGCTGCGCGGGCACGTCATCGACTTCTTCATGCTGCCGCACTGGCCGGTGTTCAACGTGGCGGACATC
TGCATCGACGTGGCAGCGGTGCTCATCCTCGTGCAGGTCTACCGCGGCGTCCGGCTCGACGGCACCCGGACGGCCCGCGA
GAGCACGCGGCCGGAGGGGCCGGAGGCGCCGGAGTGA

Upstream 100 bases:

>100_bases
CGCGCATCGACGACGGCACGTACGGCGTGTGCGAGTCCTGCGGCAACCCGATCGGCAAGATGCGGCTCATGGCGTTCCCG
CGTGCCACACTGTGCATGAC

Downstream 100 bases:

>100_bases
GCCGCGACGCCGACCATCGGGTGCTCTCGGTGCCCGAGGGCCTCGCGGGGGAGCGGGTCGACGCGGCCCTGGCGCGGATG
TTCGGCCTCTCGCGCACCCG

Product: peptidase A8, signal peptidase II

Products: NA

Alternate protein names: Prolipoprotein signal peptidase; Signal peptidase II; SPase II [H]

Number of amino acids: Translated: 198; Mature: 198

Protein sequence:

>198_residues
MQAARGTSLTGDQSDPARPRPTRPRRHRLLAVYAAVALTAYAVDVGSKILAVDRLSGRPDVQLVGDLFQLHLVRNPGAAF
STGTAYTEVLSVVAIIAVLVLLYLARRIGTVGWAVSLGLLLAGVAGNLTDRLVRSPGPLRGHVIDFFMLPHWPVFNVADI
CIDVAAVLILVQVYRGVRLDGTRTARESTRPEGPEAPE

Sequences:

>Translated_198_residues
MQAARGTSLTGDQSDPARPRPTRPRRHRLLAVYAAVALTAYAVDVGSKILAVDRLSGRPDVQLVGDLFQLHLVRNPGAAF
STGTAYTEVLSVVAIIAVLVLLYLARRIGTVGWAVSLGLLLAGVAGNLTDRLVRSPGPLRGHVIDFFMLPHWPVFNVADI
CIDVAAVLILVQVYRGVRLDGTRTARESTRPEGPEAPE
>Mature_198_residues
MQAARGTSLTGDQSDPARPRPTRPRRHRLLAVYAAVALTAYAVDVGSKILAVDRLSGRPDVQLVGDLFQLHLVRNPGAAF
STGTAYTEVLSVVAIIAVLVLLYLARRIGTVGWAVSLGLLLAGVAGNLTDRLVRSPGPLRGHVIDFFMLPHWPVFNVADI
CIDVAAVLILVQVYRGVRLDGTRTARESTRPEGPEAPE

Specific function: This protein specifically catalyzes the removal of signal peptides from prolipoproteins [H]

COG id: COG0597

COG function: function code MU; Lipoprotein signal peptidase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase A8 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001872 [H]

Pfam domain/function: PF01252 Peptidase_A8 [H]

EC number: =3.4.23.36 [H]

Molecular weight: Translated: 21264; Mature: 21264

Theoretical pI: Translated: 10.19; Mature: 10.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQAARGTSLTGDQSDPARPRPTRPRRHRLLAVYAAVALTAYAVDVGSKILAVDRLSGRPD
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCC
VQLVGDLFQLHLVRNPGAAFSTGTAYTEVLSVVAIIAVLVLLYLARRIGTVGWAVSLGLL
HHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LAGVAGNLTDRLVRSPGPLRGHVIDFFMLPHWPVFNVADICIDVAAVLILVQVYRGVRLD
HHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCC
GTRTARESTRPEGPEAPE
CCCHHHHCCCCCCCCCCC
>Mature Secondary Structure
MQAARGTSLTGDQSDPARPRPTRPRRHRLLAVYAAVALTAYAVDVGSKILAVDRLSGRPD
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCC
VQLVGDLFQLHLVRNPGAAFSTGTAYTEVLSVVAIIAVLVLLYLARRIGTVGWAVSLGLL
HHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LAGVAGNLTDRLVRSPGPLRGHVIDFFMLPHWPVFNVADICIDVAAVLILVQVYRGVRLD
HHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCC
GTRTARESTRPEGPEAPE
CCCHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]