Click here to switch to the map view.

The map label for this gene is hisC3 [H]

Identifier: 119717268

GI number: 119717268

Start: 3240906

End: 3241994

Strand: Reverse

Name: hisC3 [H]

Synonym: Noca_3044

Alternate gene names: 119717268

Gene position: 3241994-3240906 (Counterclockwise)

Preceding gene: 119717269

Following gene: 119717267

Centisome position: 65.02

GC content: 72.45

Gene sequence:

>1089_bases
GTGACCTTCCCACCCCTGCGCGAGGAGCTGCGGGGCATCGAGCCCTACGGCGCGCCGCAGCTGGACGTTCCCGTCCAGCT
CAACGTCAACGAGAACCCCTACGGGCCATCGCCGGCCTGCGCCGCTGACATCGCGGCCGCGGTCGCGCTGGCCGCGGGCA
CGCTGAACCGCTACCCCGACCGCGAGTTCGTCGACCTGCGGATGGCACTGGCGTCGTACCTCGGCCACGGCGTCACCCAC
GAGCAGGTGTGGGCGGCGAACGGGTCCAACGAGGTGATGCTCCAGCTGCTCCAGGCGTTCGGCGGCCCGGGCCGGGTGGC
GCTGAGCTTCGCCCCGACGTACTCCATGTATCCCGAGTACGCCCGCGACACCGTCACCGAGTGGGTCGTCGGGCACCGCG
AGTCCGACTTCGCGCTCGATCTCGACCACGCGCACGACCTCGTCAAGGAGCGCCAGCCGAGCGTCGTGCTGCTCCCGAGC
CCGAACAACCCGACCGGCACCGCGCTGCCGCTCGACGCCGTCACCGCGCTGTGCGAGGCGGCGGCCGGGAACGAGCAGCC
CGGGGTCGTCGTGGTCGACGAGGCGTACGGCGAGTTCCGCCGGGCCGGCACGCCCAGCGCGCTGGAGCTGCTGCCGCGGC
ACCGCAACCTGGTGGTGACCCGCACGATGAGCAAGGCGTTCGCGCTGGCCGGTGCCCGGGTCGGCTACCTGGCGGCGGCG
CCGGAGATCTGCGACGCGATCCGGGTCGTGCGGCTGCCGTACCACCTGTCCGCGGTCACCCAGGCGACCGCGCTCGCGGC
GCTACGGCACGCGCCGGAGCTGCTCGGCAAGGTCGACGAGCTGCGGGCCGAGCGCGACCGCACGGTCGACTGGCTGCGCG
AGCAGGGCCTGACGGTCGCGGACACGGATGCGAACTTCGCGCTGTTCGGGACCTTCGCCGACCGGCATGCTGTGTGGCAG
GGGTTGCTGGGCCGGGGGGTGCTGATCCGGGAGACCGGCCCGGACGGCTGGCTGCGGGTCTCGATCGGCACCGCCGAGGA
GATGCAGGCATTCAAGGACGCACTGACCCAGGTCAGGAAGGAAATGTGA

Upstream 100 bases:

>100_bases
GGCGCTCGACGCCGTGGCCGGGCACGTCGTCACGCTGGCCGAGGCCGAGGACCTCCCCGGCCACGGCGCGGCCGTCCGGG
TGCGGTTCGGGGGCTGAGCG

Downstream 100 bases:

>100_bases
TGACGAGGACGGCACGCATCGAGCGGCAGACCAGCGAGTCCAAGGTGCTCGTCGAGGTCGACCTCGACGGCACCGGGCGC
CACGACGTCTCGACCGGCGT

Product: histidinol-phosphate aminotransferase

Products: NA

Alternate protein names: Imidazole acetol-phosphate transaminase 3 [H]

Number of amino acids: Translated: 362; Mature: 361

Protein sequence:

>362_residues
MTFPPLREELRGIEPYGAPQLDVPVQLNVNENPYGPSPACAADIAAAVALAAGTLNRYPDREFVDLRMALASYLGHGVTH
EQVWAANGSNEVMLQLLQAFGGPGRVALSFAPTYSMYPEYARDTVTEWVVGHRESDFALDLDHAHDLVKERQPSVVLLPS
PNNPTGTALPLDAVTALCEAAAGNEQPGVVVVDEAYGEFRRAGTPSALELLPRHRNLVVTRTMSKAFALAGARVGYLAAA
PEICDAIRVVRLPYHLSAVTQATALAALRHAPELLGKVDELRAERDRTVDWLREQGLTVADTDANFALFGTFADRHAVWQ
GLLGRGVLIRETGPDGWLRVSIGTAEEMQAFKDALTQVRKEM

Sequences:

>Translated_362_residues
MTFPPLREELRGIEPYGAPQLDVPVQLNVNENPYGPSPACAADIAAAVALAAGTLNRYPDREFVDLRMALASYLGHGVTH
EQVWAANGSNEVMLQLLQAFGGPGRVALSFAPTYSMYPEYARDTVTEWVVGHRESDFALDLDHAHDLVKERQPSVVLLPS
PNNPTGTALPLDAVTALCEAAAGNEQPGVVVVDEAYGEFRRAGTPSALELLPRHRNLVVTRTMSKAFALAGARVGYLAAA
PEICDAIRVVRLPYHLSAVTQATALAALRHAPELLGKVDELRAERDRTVDWLREQGLTVADTDANFALFGTFADRHAVWQ
GLLGRGVLIRETGPDGWLRVSIGTAEEMQAFKDALTQVRKEM
>Mature_361_residues
TFPPLREELRGIEPYGAPQLDVPVQLNVNENPYGPSPACAADIAAAVALAAGTLNRYPDREFVDLRMALASYLGHGVTHE
QVWAANGSNEVMLQLLQAFGGPGRVALSFAPTYSMYPEYARDTVTEWVVGHRESDFALDLDHAHDLVKERQPSVVLLPSP
NNPTGTALPLDAVTALCEAAAGNEQPGVVVVDEAYGEFRRAGTPSALELLPRHRNLVVTRTMSKAFALAGARVGYLAAAP
EICDAIRVVRLPYHLSAVTQATALAALRHAPELLGKVDELRAERDRTVDWLREQGLTVADTDANFALFGTFADRHAVWQG
LLGRGVLIRETGPDGWLRVSIGTAEEMQAFKDALTQVRKEM

Specific function: Histidine biosynthesis; seventh step. [C]

COG id: COG0079

COG function: function code E; Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788332, Length=363, Percent_Identity=32.7823691460055, Blast_Score=130, Evalue=1e-31,
Organism=Saccharomyces cerevisiae, GI6322075, Length=395, Percent_Identity=28.1012658227848, Blast_Score=127, Evalue=2e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR005861
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.9 [H]

Molecular weight: Translated: 39281; Mature: 39150

Theoretical pI: Translated: 5.00; Mature: 5.00

Prosite motif: PS00599 AA_TRANSFER_CLASS_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTFPPLREELRGIEPYGAPQLDVPVQLNVNENPYGPSPACAADIAAAVALAAGTLNRYPD
CCCCCHHHHHCCCCCCCCCCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCC
REFVDLRMALASYLGHGVTHEQVWAANGSNEVMLQLLQAFGGPGRVALSFAPTYSMYPEY
HHHHHHHHHHHHHHCCCCCHHHEEECCCCHHHHHHHHHHHCCCCEEEEEECCCHHCCHHH
ARDTVTEWVVGHRESDFALDLDHAHDLVKERQPSVVLLPSPNNPTGTALPLDAVTALCEA
HHHHHHHHHHCCCCCCCEEEHHHHHHHHHHCCCCEEEEECCCCCCCCCCCHHHHHHHHHH
AAGNEQPGVVVVDEAYGEFRRAGTPSALELLPRHRNLVVTRTMSKAFALAGARVGYLAAA
HCCCCCCCEEEEECCHHHHHHCCCCHHHHHHCCCCCEEEEEHHHHHHHHHCCHHHHHHCC
PEICDAIRVVRLPYHLSAVTQATALAALRHAPELLGKVDELRAERDRTVDWLREQGLTVA
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEE
DTDANFALFGTFADRHAVWQGLLGRGVLIRETGPDGWLRVSIGTAEEMQAFKDALTQVRK
ECCCCEEEEECHHHHHHHHHHHHCCCEEEEECCCCCEEEEEECCHHHHHHHHHHHHHHHH
EM
CC
>Mature Secondary Structure 
TFPPLREELRGIEPYGAPQLDVPVQLNVNENPYGPSPACAADIAAAVALAAGTLNRYPD
CCCCHHHHHCCCCCCCCCCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCC
REFVDLRMALASYLGHGVTHEQVWAANGSNEVMLQLLQAFGGPGRVALSFAPTYSMYPEY
HHHHHHHHHHHHHHCCCCCHHHEEECCCCHHHHHHHHHHHCCCCEEEEEECCCHHCCHHH
ARDTVTEWVVGHRESDFALDLDHAHDLVKERQPSVVLLPSPNNPTGTALPLDAVTALCEA
HHHHHHHHHHCCCCCCCEEEHHHHHHHHHHCCCCEEEEECCCCCCCCCCCHHHHHHHHHH
AAGNEQPGVVVVDEAYGEFRRAGTPSALELLPRHRNLVVTRTMSKAFALAGARVGYLAAA
HCCCCCCCEEEEECCHHHHHHCCCCHHHHHHCCCCCEEEEEHHHHHHHHHCCHHHHHHCC
PEICDAIRVVRLPYHLSAVTQATALAALRHAPELLGKVDELRAERDRTVDWLREQGLTVA
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEE
DTDANFALFGTFADRHAVWQGLLGRGVLIRETGPDGWLRVSIGTAEEMQAFKDALTQVRK
ECCCCEEEEECHHHHHHHHHHHHCCCEEEEECCCCCEEEEEECCHHHHHHHHHHHHHHHH
EM
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA