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The map label for this gene is degU [H]

Identifier: 119717167

GI number: 119717167

Start: 3125279

End: 3125926

Strand: Reverse

Name: degU [H]

Synonym: Noca_2943

Alternate gene names: 119717167

Gene position: 3125926-3125279 (Counterclockwise)

Preceding gene: 119717169

Following gene: 119717166

Centisome position: 62.7

GC content: 67.44

Gene sequence:

>648_bases
GTGAAGGCGGCGAGGATCGCGGTCCTGGTGGTCGACGACCACACGCTCCATCGCGACGGCACCAGGCGCATCCTGGAGCA
GTACGACGACGTGGACGTCGTCGGTGACGCCGCGTCGGGTGAGGACGCGTTGGCGATGGTCAACCGGTTGCATCCCCGCG
TCGTCCTCATGGACATCCGCCTGCCAGGGATGAACGGCATCGAGGCGACCCGCAGGATCCGAGAGCGACACCCTGACACG
CGGGTGCTCATCGTGACCGCGTACGACGACGAGGAGTACGTCCGCGGGGCGTTCGACGTCGGGGCCGCTGGCTACCTCAG
CAAGACCGCCCCCGGCCGCGAACTGGTCGAGGCCGTCCGCGCTGTAGCCGGCGGCAACAGCGTGCTGCAGCCGACATTGA
TGGCTGCCCTGCTCGCCAAGCGCTCTAGTCCTGCCAACACGCTCACCGATAGGGAGAGGGCGGTGTTGCGACTACTGGCA
GAGGGGATGCACAACAAGCAGATCGCAAGCCGCCTCGGCATCAGCGCCCGCACCGTCGAACGGCATTGCGACAGGATCTA
CGGCAAGCTCGGCGTGACCTCTCGGACCGAGGCCGTCGTCCGAGCCATCTCCGCCAACCTGCTCGACGTCTCGGATGTCG
CGCGCTGA

Upstream 100 bases:

>100_bases
CGACAGGGCGATCACCGCCGTCCGCCGTAGCGGAATCGGGCCACTTGGTGTGGGTGATTTCCCCTATCTCCGAGCGCTCG
GCCGGCGTACCGTCGATCGT

Downstream 100 bases:

>100_bases
GGCCGCACCGATGACCTCGCCCGCTGCCGACGGACCGCGCGGGATGCTCGGAGCCCTGGCCCAGGTCAGGCCGCCGGTGC
GCGAACCACGCTTCTGGGTG

Product: two component LuxR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 215; Mature: 215

Protein sequence:

>215_residues
MKAARIAVLVVDDHTLHRDGTRRILEQYDDVDVVGDAASGEDALAMVNRLHPRVVLMDIRLPGMNGIEATRRIRERHPDT
RVLIVTAYDDEEYVRGAFDVGAAGYLSKTAPGRELVEAVRAVAGGNSVLQPTLMAALLAKRSSPANTLTDRERAVLRLLA
EGMHNKQIASRLGISARTVERHCDRIYGKLGVTSRTEAVVRAISANLLDVSDVAR

Sequences:

>Translated_215_residues
MKAARIAVLVVDDHTLHRDGTRRILEQYDDVDVVGDAASGEDALAMVNRLHPRVVLMDIRLPGMNGIEATRRIRERHPDT
RVLIVTAYDDEEYVRGAFDVGAAGYLSKTAPGRELVEAVRAVAGGNSVLQPTLMAALLAKRSSPANTLTDRERAVLRLLA
EGMHNKQIASRLGISARTVERHCDRIYGKLGVTSRTEAVVRAISANLLDVSDVAR
>Mature_215_residues
MKAARIAVLVVDDHTLHRDGTRRILEQYDDVDVVGDAASGEDALAMVNRLHPRVVLMDIRLPGMNGIEATRRIRERHPDT
RVLIVTAYDDEEYVRGAFDVGAAGYLSKTAPGRELVEAVRAVAGGNSVLQPTLMAALLAKRSSPANTLTDRERAVLRLLA
EGMHNKQIASRLGISARTVERHCDRIYGKLGVTSRTEAVVRAISANLLDVSDVAR

Specific function: Regulating factor for the production of extracellular proteases. The N-terminal region acts as an inhibitor, whereas the C-terminal region carries enhancing activity [H]

COG id: COG2197

COG function: function code TK; Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788222, Length=210, Percent_Identity=35.2380952380952, Blast_Score=125, Evalue=3e-30,
Organism=Escherichia coli, GI1788521, Length=204, Percent_Identity=36.7647058823529, Blast_Score=119, Evalue=1e-28,
Organism=Escherichia coli, GI1787473, Length=200, Percent_Identity=37, Blast_Score=115, Evalue=2e-27,
Organism=Escherichia coli, GI1790102, Length=192, Percent_Identity=34.8958333333333, Blast_Score=103, Evalue=7e-24,
Organism=Escherichia coli, GI1786747, Length=200, Percent_Identity=28, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI1788712, Length=188, Percent_Identity=28.1914893617021, Blast_Score=95, Evalue=3e-21,
Organism=Escherichia coli, GI1788546, Length=194, Percent_Identity=29.3814432989691, Blast_Score=78, Evalue=4e-16,
Organism=Escherichia coli, GI87082052, Length=103, Percent_Identity=33.0097087378641, Blast_Score=66, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 23484; Mature: 23484

Theoretical pI: Translated: 9.05; Mature: 9.05

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00622 HTH_LUXR_1 ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAARIAVLVVDDHTLHRDGTRRILEQYDDVDVVGDAASGEDALAMVNRLHPRVVLMDIR
CCCCEEEEEEECCCCCCCCHHHHHHHHCCCCCEECCCCCCHHHHHHHHHCCCEEEEEEEE
LPGMNGIEATRRIRERHPDTRVLIVTAYDDEEYVRGAFDVGAAGYLSKTAPGRELVEAVR
CCCCCCHHHHHHHHHHCCCCEEEEEEEECCHHHHHHHHHCCCCCHHCCCCCHHHHHHHHH
AVAGGNSVLQPTLMAALLAKRSSPANTLTDRERAVLRLLAEGMHNKQIASRLGISARTVE
HHHCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHCCHHHHHH
RHCDRIYGKLGVTSRTEAVVRAISANLLDVSDVAR
HHHHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHCC
>Mature Secondary Structure
MKAARIAVLVVDDHTLHRDGTRRILEQYDDVDVVGDAASGEDALAMVNRLHPRVVLMDIR
CCCCEEEEEEECCCCCCCCHHHHHHHHCCCCCEECCCCCCHHHHHHHHHCCCEEEEEEEE
LPGMNGIEATRRIRERHPDTRVLIVTAYDDEEYVRGAFDVGAAGYLSKTAPGRELVEAVR
CCCCCCHHHHHHHHHHCCCCEEEEEEEECCHHHHHHHHHCCCCCHHCCCCCHHHHHHHHH
AVAGGNSVLQPTLMAALLAKRSSPANTLTDRERAVLRLLAEGMHNKQIASRLGISARTVE
HHHCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHCCHHHHHH
RHCDRIYGKLGVTSRTEAVVRAISANLLDVSDVAR
HHHHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7765823 [H]