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The map label for this gene is degS [H]

Identifier: 119717166

GI number: 119717166

Start: 3123811

End: 3125268

Strand: Reverse

Name: degS [H]

Synonym: Noca_2942

Alternate gene names: 119717166

Gene position: 3125268-3123811 (Counterclockwise)

Preceding gene: 119717167

Following gene: 119717164

Centisome position: 62.68

GC content: 69.41

Gene sequence:

>1458_bases
ATGACCTCGCCCGCTGCCGACGGACCGCGCGGGATGCTCGGAGCCCTGGCCCAGGTCAGGCCGCCGGTGCGCGAACCACG
CTTCTGGGTGGTTCAGGCGGCGGTGCTGACCCTCGCCGGAGTTCACGACTTCGTGCTGGACAAGCTGCACGCCCACTACC
TCGCAGGGGTGCCCGCTCCTACAACGTCGGCACTGTTGCTCATCCCGGTCGTCTACGCCGCGCTGAACTTCGGTGTCCGC
GGGGCGGTGGGCACCTCGCTGTGGGCGACGGTCCTCATCGTCCCTCACTGGCTCATCTCGCCGCAGCTTCCGGATTCCCG
GATTCACTTCTGGATCGAGGTCGGATACCTCGTGGTGCTCAACGTCGTCGCCATCGTCGTGGGAGTGCGAGTCGAGGGCG
AGCGTCTGGCCCGGCGTCGTGCCGAGCACGCGCTCGAGGTTGCAGAGAACGCCGAGGCGCGCTATTACCGGCTCTTCGAG
GACCAACCCGCTCCCGTGATGATCGCAGACGCGGCGGGAGCCGTGACAGAAGCGAACACCGCGGCCACGGCGCTGTTTGG
ACGCGACACGGTCGGCCTGCGAGTCGATGAACTTCTCGGCGTTGGCATCGCCACGCTCCTCGACGGCCGACCCCGGTGCC
TCGACGTCAGGGACCGGGACGGTCGGACGTTGAGGCTCGTCCCCACCACCCATCGCGTGACCACCGCGGGCAACGCCGAG
CTCGCCCAGGTCGTGCTGACCGACGTGACTGAGCAGCACCGGCGTGAGGAGGAGGAACGGCTGTTCGCTGGTCGGCTGCT
GAAGGTGCAGGAGGACGAGCGCCGGGCCCTGGCTCGCGAACTGCACGACGACCCCTTGCAGAACCTCACCTACCTCAGCC
GCGCTCTCGACGACCTGGGACATCGGGCGGAGACGCCTCCCGAACTTGCGGGCCAGTTGGTCGATGCGAGCGCGGTTGCG
GAGGACGCCGCCGTGGCGCTGCGGAAGGTGATCCACGGCCTTCGACCTCCGGTGCTCGACGACCTCGGCCTCGTCGCGGC
CCTGCGCCAACTCGCCCAGGAGGTACGCCGACGGACCGGCCTGGCCGTCGAACTCCGGGTCAGGGGACACGAGGTGCGGC
TCCCGCCCGGTCTCGAGCTGGCCGCCTATCGCATCGCCCAAGAGGCCCTCAACAACGTCGTCCGGCACGCCAGAGCCAGC
CGTGTCGAGGTCTGCGTCTGCTTCGACCGGGAGCTCGAGCTCACCATCACCGACGACGGACTGGGGTGGTCCGAACCCGA
GCGCGGGGACGGGGCGAAAGCCAGCGGGCTAGGGCTGATCGGGATGCGGGAACGCGTGAACATGGCCGGTGGCACGTTGA
GCGTCACCCAGCGTTCCGGTCACGGCACCCGAGTGCGCGCCGTGGTGCCGGTCCCCAGCGTCGCGGTCAGCCCAGAGTCA
TCCTCGGCTCGCCGTTGA

Upstream 100 bases:

>100_bases
TACGGCAAGCTCGGCGTGACCTCTCGGACCGAGGCCGTCGTCCGAGCCATCTCCGCCAACCTGCTCGACGTCTCGGATGT
CGCGCGCTGAGGCCGCACCG

Downstream 100 bases:

>100_bases
GCAGGCCGGTGCCTGCGATCGAGCACTTTCCGCCCCGTGGGGCTCCGGCGTTCCAGGCCTGCCGCACGCAGGAACGGGTC
GCGAGCTGGGCCCAGTAGTT

Product: ATPase domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 485; Mature: 484

Protein sequence:

>485_residues
MTSPAADGPRGMLGALAQVRPPVREPRFWVVQAAVLTLAGVHDFVLDKLHAHYLAGVPAPTTSALLLIPVVYAALNFGVR
GAVGTSLWATVLIVPHWLISPQLPDSRIHFWIEVGYLVVLNVVAIVVGVRVEGERLARRRAEHALEVAENAEARYYRLFE
DQPAPVMIADAAGAVTEANTAATALFGRDTVGLRVDELLGVGIATLLDGRPRCLDVRDRDGRTLRLVPTTHRVTTAGNAE
LAQVVLTDVTEQHRREEEERLFAGRLLKVQEDERRALARELHDDPLQNLTYLSRALDDLGHRAETPPELAGQLVDASAVA
EDAAVALRKVIHGLRPPVLDDLGLVAALRQLAQEVRRRTGLAVELRVRGHEVRLPPGLELAAYRIAQEALNNVVRHARAS
RVEVCVCFDRELELTITDDGLGWSEPERGDGAKASGLGLIGMRERVNMAGGTLSVTQRSGHGTRVRAVVPVPSVAVSPES
SSARR

Sequences:

>Translated_485_residues
MTSPAADGPRGMLGALAQVRPPVREPRFWVVQAAVLTLAGVHDFVLDKLHAHYLAGVPAPTTSALLLIPVVYAALNFGVR
GAVGTSLWATVLIVPHWLISPQLPDSRIHFWIEVGYLVVLNVVAIVVGVRVEGERLARRRAEHALEVAENAEARYYRLFE
DQPAPVMIADAAGAVTEANTAATALFGRDTVGLRVDELLGVGIATLLDGRPRCLDVRDRDGRTLRLVPTTHRVTTAGNAE
LAQVVLTDVTEQHRREEEERLFAGRLLKVQEDERRALARELHDDPLQNLTYLSRALDDLGHRAETPPELAGQLVDASAVA
EDAAVALRKVIHGLRPPVLDDLGLVAALRQLAQEVRRRTGLAVELRVRGHEVRLPPGLELAAYRIAQEALNNVVRHARAS
RVEVCVCFDRELELTITDDGLGWSEPERGDGAKASGLGLIGMRERVNMAGGTLSVTQRSGHGTRVRAVVPVPSVAVSPES
SSARR
>Mature_484_residues
TSPAADGPRGMLGALAQVRPPVREPRFWVVQAAVLTLAGVHDFVLDKLHAHYLAGVPAPTTSALLLIPVVYAALNFGVRG
AVGTSLWATVLIVPHWLISPQLPDSRIHFWIEVGYLVVLNVVAIVVGVRVEGERLARRRAEHALEVAENAEARYYRLFED
QPAPVMIADAAGAVTEANTAATALFGRDTVGLRVDELLGVGIATLLDGRPRCLDVRDRDGRTLRLVPTTHRVTTAGNAEL
AQVVLTDVTEQHRREEEERLFAGRLLKVQEDERRALARELHDDPLQNLTYLSRALDDLGHRAETPPELAGQLVDASAVAE
DAAVALRKVIHGLRPPVLDDLGLVAALRQLAQEVRRRTGLAVELRVRGHEVRLPPGLELAAYRIAQEALNNVVRHARASR
VEVCVCFDRELELTITDDGLGWSEPERGDGAKASGLGLIGMRERVNMAGGTLSVTQRSGHGTRVRAVVPVPSVAVSPESS
SARR

Specific function: Involved in a sensory transduction pathway that affect the production of enzymes that degrade polymeric carbon and nitrogen sources. DegS probably acts as a kinase that phosphorylates degU [H]

COG id: COG4585

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI87082311, Length=213, Percent_Identity=37.0892018779343, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI1788812, Length=197, Percent_Identity=33.502538071066, Blast_Score=77, Evalue=4e-15,
Organism=Escherichia coli, GI1787474, Length=201, Percent_Identity=30.8457711442786, Blast_Score=71, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR008595
- InterPro:   IPR011712
- InterPro:   IPR005467
- InterPro:   IPR016381 [H]

Pfam domain/function: PF05384 DegS; PF02518 HATPase_c; PF07730 HisKA_3 [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 52652; Mature: 52521

Theoretical pI: Translated: 6.90; Mature: 6.90

Prosite motif: PS50112 PAS ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSPAADGPRGMLGALAQVRPPVREPRFWVVQAAVLTLAGVHDFVLDKLHAHYLAGVPAP
CCCCCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
TTSALLLIPVVYAALNFGVRGAVGTSLWATVLIVPHWLISPQLPDSRIHFWIEVGYLVVL
CCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEHHHHHHHH
NVVAIVVGVRVEGERLARRRAEHALEVAENAEARYYRLFEDQPAPVMIADAAGAVTEANT
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCEEEECCCCCCCCCCH
AATALFGRDTVGLRVDELLGVGIATLLDGRPRCLDVRDRDGRTLRLVPTTHRVTTAGNAE
HHHHEECCCCCCCCHHHHHHHHHHHHHCCCCCEECCCCCCCCEEEEEECCCEEEECCCHH
LAQVVLTDVTEQHRREEEERLFAGRLLKVQEDERRALARELHDDPLQNLTYLSRALDDLG
HHHHHHHHHHHHHHHHHHHHHHHHHHHEECCHHHHHHHHHHCCCHHHHHHHHHHHHHHHC
HRAETPPELAGQLVDASAVAEDAAVALRKVIHGLRPPVLDDLGLVAALRQLAQEVRRRTG
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCC
LAVELRVRGHEVRLPPGLELAAYRIAQEALNNVVRHARASRVEVCVCFDRELELTITDDG
CEEEEEECCCEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCEEEEEECCC
LGWSEPERGDGAKASGLGLIGMRERVNMAGGTLSVTQRSGHGTRVRAVVPVPSVAVSPES
CCCCCCCCCCCCCCCCCCEEEHHHHHHHCCCEEEEEEECCCCCEEEEEECCCCEEECCCC
SSARR
CCCCC
>Mature Secondary Structure 
TSPAADGPRGMLGALAQVRPPVREPRFWVVQAAVLTLAGVHDFVLDKLHAHYLAGVPAP
CCCCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
TTSALLLIPVVYAALNFGVRGAVGTSLWATVLIVPHWLISPQLPDSRIHFWIEVGYLVVL
CCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEHHHHHHHH
NVVAIVVGVRVEGERLARRRAEHALEVAENAEARYYRLFEDQPAPVMIADAAGAVTEANT
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCEEEECCCCCCCCCCH
AATALFGRDTVGLRVDELLGVGIATLLDGRPRCLDVRDRDGRTLRLVPTTHRVTTAGNAE
HHHHEECCCCCCCCHHHHHHHHHHHHHCCCCCEECCCCCCCCEEEEEECCCEEEECCCHH
LAQVVLTDVTEQHRREEEERLFAGRLLKVQEDERRALARELHDDPLQNLTYLSRALDDLG
HHHHHHHHHHHHHHHHHHHHHHHHHHHEECCHHHHHHHHHHCCCHHHHHHHHHHHHHHHC
HRAETPPELAGQLVDASAVAEDAAVALRKVIHGLRPPVLDDLGLVAALRQLAQEVRRRTG
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCC
LAVELRVRGHEVRLPPGLELAAYRIAQEALNNVVRHARASRVEVCVCFDRELELTITDDG
CEEEEEECCCEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCEEEEEECCC
LGWSEPERGDGAKASGLGLIGMRERVNMAGGTLSVTQRSGHGTRVRAVVPVPSVAVSPES
CCCCCCCCCCCCCCCCCCEEEHHHHHHHCCCEEEEEEECCCCCEEEEEECCCCEEECCCC
SSARR
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7765823 [H]